• Proceedings of the Korean Reliability Society Conference
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• 2000.04a
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• pp.115-121
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• 2000

영광1,2,3,4호기 비상디젤발전기(EDG)의 신뢰도 수준을 파악하기 위하여 시험관리대장과 운전불능관리대장, 그리고 발전과장일지를 조사하여 신뢰도 및 이용불능도를 분석하였다. 신뢰도는 EDG의 유효시험 데이터를 이용하여 계산하는 유효 신뢰도와 무효시험까지 포함하여 계산하는 전체 신뢰도로 구분하였으며, 이용불능도는 EDG를 정비모드로 전환시키고 작업함으로서 이용불능을 유발하였던 정비 이용불능도, 그리고 유효시험 실패로 인하여 정비모드를 유발하는 경우에 잠재적 고장 시간까지 포함한 종합 이용불능도로 구분하였다. 분석 결과로서 영광1호기 EDG의 유효 신뢰도는 0.995, 2호기는 1.0으로 매우 높은 수준을 유지하고 있었으며, 이용불능도의 역인 이용가능도는 1호기 A계열 EDG는 0.978, B계열은 0.979, 2호기 A는 0.991, B는 0.976으로 높은 수준이었다. 3,4호기 EDG의 유효 신뢰도는 1,2호기와 마찬가지로 높은 수준이었으나, 전체 신뢰도는 텐덤형 디젤엔진이 갖는 근본적 부하불균형 문제 때문에 낮은 수준이었다. 따라서, 영광3,4호기 EDG의 신뢰도를 높이기 위해 많은 노력을 기울였으며, 이를 통해 EDG 신뢰도 개선에 도움이 된 것으로 분석되었다.

• Food Science of Animal Resources
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• v.32 no.6
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• pp.776-782
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• 2012

Marbling (intramuscular fat) is the most economically important meat quality trait in Hanwoo (Korean cattle). The endothelial differentiation G-protein coupled receptor 1 (EDG1) gene, involved in blood vessel formation, is located within the genomic region of a quantitative trait locus (QTL) for marbling on bovine chromosome 3. Thus, the EDG1 gene can be considered as a positional and functional candidate gene for meat quality in beef cattle. This study aimed to identify single nucleotide polymorphisms (SNPs) in the EDG1 gene and to evaluate their associations with carcass traits in Hanwoo population. We have sequenced a fragment of 5'-UTR of the EDG1 gene and identified one SNP. Genotyping of the g.166A>G SNP marker was carried out using PCR-RFLP analysis in 309 Hanwoo steers in order to evaluate their association with carcass traits. The g.166A>G SNP marker showed a significant effect on the marbling score. Animals with the GG genotype had higher marbling score compared with AA and AG genotypes (p<0.05). This SNP marker also showed a significant additive effects for the marbling score (p<0.05). These results suggest that the EDG1 gene can be used as a molecular marker for DNA marker-assisted selection in order to increase the levels of the marbling score in Hanwoo.

• Korean Journal of Agricultural Science
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• v.39 no.3
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• pp.349-355
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• 2012

Thyroglobulin (TG) gene was known to be regulated fat cell growth and differentiation and the endothelial differentiation sphingolipid G-protein-coupled receptor 1 (EDG1) gene involves blood vessel formation and known to be affecting carcass traits in beef cattle. The aim of this study was to identify the single nucleotide polymorphisms (SNPs) in both TG and EDG1 genes and to analyze the association with carcass traits in Korean cattle (Hanwoo). The T354C SNP in TG gene located at the 3' flanking region and c.-312A>G SNP located at 3'-UTR of EDG1 gene were used for genotyping the animals using PCR-RFLP method. Three genotypes were identified in T354C SNP in TG gene and only two AA and AG genotypes were observed for the c.-312A>G SNP in EDG1 gene. The results indicated that T354C SNP in TG gene was not significantly associated with carcass traits. However, the c.-312A>G SNP in EDG1 gene had significant effects on backfat thickness (BF) and yield index (YI). These results may provide valuable information for further candidate gene studies affecting carcass traits in Korean cattle and may use as marker assisted selection for improving the quality of meat in Hanwoo.

• Biomolecules & Therapeutics
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• v.19 no.4
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• pp.419-424
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• 2011

Galla Rhois and its components are known to possess anti-infl ammatory properties. In the present study, we prepared equilibrium mixture of ethyl m-digallate and ethyl p-digallate isomers (EDG) from Galla Rhois and examined its effect on nitric oxide (NO) production in murine macrophage cell line. Treatment of RAW264.7 macrophages with EDG signifi cantly inhibited NO production and inducible nitric oxide synthase (iNOS) expression stimulated by LPS, as assessed by Western blot and quantitative RT-PCR analyses. We also demonstrated that EDG treatment led to an increase in heme oxygenase-1 (HO-1) mRNA and protein expression. EDG treatment also enhanced expression level of nuclear factor-erythroid 2-related factor 2 (Nrf2) in nucleus, which is critical for transcriptional induction of HO-1. Treatment with SnPP (tin protoporphyrin IX), a selective HO-1 inhibitor, reversed EDG-mediated inhibition of nitrite production, suggesting that HO-1 plays an important role in the suppression of NO production by EDG. Taken together, these results indicate that EDG isolated from Galla Rhois suppresses LPS-stimulated NO production in RAW 264.7 macrophages via HO-1 induction.

• Proceedings of the KIEE Conference
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• 2015.07a
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• pp.689-690
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• 2015

국내 최초 원전인 고리1호기는 지난 2007년 30년의 운전수명을 마친 뒤 정부의 안전점검을 거쳐 10년간 연장운전에 들어갔다. 이 과정에서 원전의 비상 전원 계통 신뢰성 확보를 위해 설계수명을 초과한 35년 된 노후 비상디젤발전기(Emergency Diesel Generator, 이하 EDG)를 지난 2013년 4월부터 9월까지 약 6개월에 걸쳐 교체하게 되었으며, 국내 원전 EDG 총 42대 중 18대가 20년 넘게 운영되고 있고, 2025년까지 고리 1호기를 후속으로 월성1호기, 고리2호기, 고리3호기, 고리4호기, 한빛1호기 순으로 40년 승인된 운전 인허가 기간이 만료된다.[1]. 본 연구에서, Class 1E EDG 교체 시 신규 EDG 설계기준, 용량결정, 해석 및 평가에 대한 기술적 방법들을 고리1호기의 사례를 통해 고찰하였다.

• Transactions of the Korean Society of Pressure Vessels and Piping
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• v.5 no.1
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• pp.32-37
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• 2009

The emergency diesel generator (EDG) in a nuclear power plant (NPP) shall start within 10 secondss and supply electrical power to engineered safety features within one minute and less if a loss of offsite power (LOOP), A design-basis event, or their combination occur. Each NPP has an EDG set consisting of two diesel generators for redundancy. In addition to the EDG set, an alternate Alternating Current Diesel Generator (AAC DG) is installed and shared by several units to cope with a station black out (SBO), i.e., loss of the offsite power concurrent with reactor trip and unavailability of the EDG set. The objective of this study is to analyze the failure data of emergency diesel generators reported in overseas nuclear power plants.

• Journal of the Korean Society of Safety
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• v.25 no.3
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• pp.118-122
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• 2010

In order to provide the necessary operation flexibility during the Nuclear power operation, the extension of existing allowed outage time(AOT) is needed. The extension of AOT affects the Nuclear power plant safety. The validity of changed technical specification requirements should be proved by the safety assessments. In this paper, we evaluated the extension of emergency diesel generator AOT for a single inoperable emergency diesel generator(EDG) from 3days to 7days, 10days and 14days. Finally, the AOT extension contributes the NPP performances through decreasing the unexpected plant trips, reinforcing maintenance and avoiding risks due to unnecessary operation mode changes when the NPP is under the surveillance tests or maintenance.

• Bulletin of the Korean Chemical Society
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• v.35 no.2
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• pp.436-440
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• 2014

The ${\alpha}$-Effect; Ground state; Transition state; Intramolecular H-bonding; Yukawa-Tsuno plot; Second-order rate constants for aminolysis of 2-chloro-4-nitrophenyl X-substituted-benzoates (1a-h) have been measured spectrophotometrically in 80 mol % $H_2O/20$ mol % DMSO at $25.0^{\circ}C$. The Br${\emptyset}$nsted-type plot for the reactions of 2-chloro-4-nitrophenyl benzoate (1d) with a series of primary amines curves downward, which has been taken as evidence for a stepwise mechanism with a change in rate-determining step (RDS). The Hammett plots for the reactions of 1a-h with hydrazine and glycylglycine are nonlinear while the Yukawa-Tsuno plots exhibit excellent linearity with ${\rho}_X=1.22-1.35$ and ${\gamma}= 0.57-0.59$, indicating that the nonlinear Hammett plots are not due to a change in RDS but are caused by stabilization of substrates possessing an electron-donating group (EDG) through resonance interactions between the EDG and C=O bond of the substrates. The ${\alpha}$-effect exhibited by hydrazine increases as the substituent X changes from a strong EDG to a strong electron-withdrawing group (EWG). It has been concluded that destabilization of hydrazine through the electronic repulsion between the adjacent nonbonding electrons is not solely responsible for the substituent dependent ${\alpha}$-effect but stabilization of the transition state is also a plausible origin of the ${\alpha}$-effect.

• Bulletin of the Korean Chemical Society
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• v.35 no.1
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• pp.93-97
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• 2014

A kinetic study is reported on nucleophilic substitution reactions of 4-nitrophenyl X-substituted-2-methylbenzoates (5a-e) with a series of cyclic secondary amines in MeCN at $25.0{\pm}0.1^{\circ}C$. The Hammett plots for the aminolysis of 5a-e are nonlinear, e.g., substrates possessing an electron-donating group (EDG) in the benzoyl moiety deviate negatively from the linear line composed of substrates bearing no EDG. In contrast, the Yukawa-Tsuno plots for the same reactions exhibit excellent linear correlations with ${\rho}_X$ = 0.30-0.59 and r = 0.90-1.15, indicating that the nonlinear Hammett plots are caused by stabilization of the substrates possessing an EDG through resonance interactions but are not due to a change in the rate-determining step (RDS). The Br${\phi}$nsted-type plots are linear with ${\beta}_{nuc}$ = 0.66-0.82. Thus, the aminolysis of 5a-e has been suggested to proceed through a stepwise mechanism in which departure of the leaving group occurs at the RDS. The ${\rho}_X$ and ${\beta}_{nuc}$ values for the aminolysis of 5a-e increase as the reactivity of the substrates and amines increases, indicating that the reactivity-selectivity principle is not applicable to the current reactions.

• Bulletin of the Korean Chemical Society
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• v.32 no.6
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• pp.1907-1911
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• 2011

A kinetic study is reported for nucleophilic substitution reactions of 4-pyridyl X-substituted benzoates 7a-e with a series of alicyclic secondary amines in H2O. The Br${\o}$nsted-type plot for the reactions of 4-pyridyl benzoate 7c is linear with ${\beta}_{nuc}$ = 0.71. The corresponding reactions of 2-pyridyl benzoate 6, which is less reactive than 7c, resulted in also a linear Br${\o}$nsted-type plot with ${\beta}_{nuc}$ = 0.77. The fact that the more reactive 7c results in a smaller ${\beta}_{nuc}$ value appears to be in accord with the reactivity-selectivity principle. The aminolysis of 7c has been suggested to proceed through a stepwise mechanism in which breakdown of the intermediate is the rate-determining step (RDS). The Hammett plot for the reactions of 7a-e with piperidine consists of two intersecting straight lines, i.e., ${\rho}_X$ = 1.47 for substrates possessing an electron-donating group (EDG) and ${\rho}_X$ = 0.91 for those possessing an electron-withdrawing group (EWG). In contrast, the corresponding Yukawa-Tsuno plot exhibits excellent linear correlation with ${\rho}_X$ = 0.79 and r = 0.56. Thus, it has been concluded that the nonlinear Hammett plot is not due to a change in the RDS but is caused by stabilization of the ground state of the substrates possessing an EDG through resonance interaction between the EDG and the C=O bond of the substrates.