• Proceedings of the Korea Institutes of Information Security and Cryptology Conference
• /
• 1995.11a
• /
• pp.341-364
• /
• 1995

본 고에서는 DAVIC 에서 권고 중인 VOD (video-on-demand) 시스템에 대한 액세스 제어 기법을 분석하고, 이를 바탕으로 국내 VOD 시스템에 적용 가능한 액세스 제어 기법을 제시한다. 이를 위하여 DAVIC 의 VOD 시스템에서의 보안 기법을 분석하고, 보안 시스템을 위한 참조 모델과 요구되는 서비스 및 보안 메카니즘을 분석한 후, 국내 VOD 시스템에 적용 가능한 액세스 제어 시스템 실현 방안과 정보보호 메카니즘을 제시한다. 그리고 방송용 서비스에 적용 가능한 ECM 채널을 DES, MD5, 그리고 RSA 알고리즘을 이용하여 C 언어로 구현하고 관련 동작을 시뮬레이션한다. 시뮬레이션 결과 ECM 채널이 정상 동작됨을 확인한다. 제시된 방안은 국내 VOD 시스템 실현시 유용하게 활용될 수 있다.

• Defense and Technology
• /
• no.11 s.47
• /
• pp.29-40
• /
• 1982

• The Journal of the Society of Korean Medicine Diagnostics
• /
• v.15 no.3
• /
• pp.261-270
• /
• 2011

Objectives: The purpose of our study is to know Temperament & Character of each Eight Constitutions (Hepatonia, Cholecystonia, Pancreotonia, Gastrotonia, Pulmotonia, Colonotonia, Renotonia, Vesicotonia) classified by the short form Eight-constitution medicine questionnaire (ECM-32) test. Methods: We analyzed the result of ECM-32 test and Temperament and Character Inventory (TCI) submitted by 32 patients who had visited the ${\triangle}{\triangle}$ oriental medicine clinic in Nowon-gu, Seoul between September and October at 2011. Results: -The participants were classified as one of Eight Constitutions (3 Hepatonia(9.4%), 7 Cholecystonia, (21.9%), 3 Pancreotonia(9.4%), 0 Gastrotonia(0%), 5 Pulmotonia(15.6%), 4 Colonotonia(12.5%), 6 Renotonia(18.8%), 4 Vesicotonia(12.5%)) by ECM-32. -The seven dimensions of TCI were compared between the different Eight Constitutions using Kruskal-Wallis test. There were significant differences between Hepatonia and Pulmotonia, Hepatonia and Colonotonia, Cholecystonia and Pulmotonia, Pulmotonia and Renotonia, Pulmotonia and Vesicotonia in the Reward Dependence of Temperament dimensions. -The Subsclaes of TCI were compared between the different Eight Constitutions using Kruskal-Wallis test. There were significant differences between Cholecystonia and Pulmotonia, Pulmotonia and Renotonia, Pulmotonia and Vesicotonia in the RD3. There were significant differences between Hepatonia and Cholecystonia, Hepatonia and Pancreotonia, Hepatonia and Pulmotonia, Hepatonia and Renotonia in the RD4. Conclusions: There is not a significant interrelationship between Feature of each Eight Constitutions and Temperament & Character in TCI. This study is meaningful because it is the first study to verify Temperament and Character of Eight Constitutions. Further studies with increased case and improved questionnaire are needed to supplement this research.

• The Korean Journal of Physiology and Pharmacology
• /
• v.14 no.6
• /
• pp.385-390
• /
• 2010

Excessive extracellular matrix (ECM) accumulation is the main feature of chronic renal disease including diabetic nephropathy. Plasminogen activator inhibitor (PAI)-1 is known to play an important role in renal ECM accumulation in part through suppression of plasmin generation and matrix metalloproteinase (MMP) activation. The present study examined the effect of PAI-1 antisense oligodeoxynucleotide (ODN) on fibronectin upregulation and plasmin/MMP suppression in primary mesangial cells cultured under high glucose (HG) or transforming growth factor (TGF)-${\beta}1$, major mediators of diabetic renal ECM accumulation. Growth arrested and synchronized rat primary mesangial cells were transfected with $1\;{\mu}M$ phosphorothioate-modified antisense or control mis-match ODN for 24 hours with cationic liposome and then stimulated with 30 mM D-glucose or 2 ng/ml TGF-${\beta}1$. PAl-1 or fibronectin protein was measured by Western blot analysis. Plasmin activity was determined using a synthetic fluorometric plasmin substrate and MMP-2 activity analyzed using zymography. HG and TGF-${\beta}1$ significantly increased PAI-1 and fibronectin protein expression as well as decreased plasmin and MMP-2 activity. Transient transfection of mesangial cells with PAI-1 antisense ODN, but not mis-match ODN, effectively reversed basal as well as HG- and TGF-${\beta}1$-induced suppression of plasmin and MMP-2 activity. Both basal and upregulated fibronectin secretion were also inhibited by PAI-1 antisense ODN. These data confirm that PAI-1 plays an important role in ECM accumulation in diabetic mesangium through suppression of protease activity and suggest that PAI-1 antisense ODN would be an effective therapeutic strategy for prevention of renal fibrosis including diabetic nephropathy.

• The Journal of Advanced Prosthodontics
• /
• v.6 no.5
• /
• pp.351-360
• /
• 2014

PURPOSE. The aim of present study was to identify characteristic and response of mouse bone marrow (BM) derived low-adherent bone marrow mesenchymal stem cells (BMMSCs) obtained by quantification of extracellular matrix (ECM). MATERIALS AND METHODS. Non-adherent cells acquired by ECM coated dishes were termed low-adherent BMMSCs and these cells were analyzed by in vitro and in vivo methods, including colony forming unit fibroblast (CFU-f), bromodeoxyuridine (BrdU), multi-potential differentiation, flow cytometry and transplantation into nude mouse to measure the bone formation ability of these low-adherent BMMSCs. Titanium (Ti) discs with machined and anodized surfaces were prepared. Adherent and low-adherent BMMSCs were cultured on the Ti discs for testing their proliferation. RESULTS. The amount of CFU-f cells was significantly higher when non-adherent cells were cultured on ECM coated dishes, which was made by 7 days culturing of adherent BMMSCs. Low-adherent BMMSCs had proliferation and differentiation potential as adherent BMMSCs in vitro. The mean amount bone formation of adherent and low-adherent BMMSCs was also investigated in vivo. There was higher cell proliferation appearance in adherent and low-adherent BMMSCs seeded on anodized Ti discs than machined Ti discs by time. CONCLUSION. Low-adherent BMMSCs acquired by ECM from non-adherent cell populations maintained potential characteristic similar to those of the adherent BMMSCs and therefore could be used effectively as adherent BMMSCs in clinic.

• KDI Journal of Economic Policy
• /
• v.29 no.2
• /
• pp.135-157
• /
• 2007

The goal of this paper is to examine the validity of nonlinear Taylor rules in Korea. To perform our tests, we utilize new IV ECM threshold cointegration tests that are invariant to nuisance parameters. The new tests have a standard chi-square distribution and the same critical values can be used throughout. This is in contrast to OLS ECM threshold cointegration tests, which depend on nuisance parameters and have nonstandard distributions. After finding significant support for nonlinear cointegration, we find that the Bank of Korea raises the call rate of interest only when inflation is above a threshold rate. We additionally find that the Bank of Korea increases the call rate of interest to possibly counter domestic currency deprecation only when the rate of currency deprecation exceeds a threshold.

• Toxicological Research
• /
• v.12 no.2
• /
• pp.213-221
• /
• 1996

In order to develop a suitable secondary renal disease model and diagnostic markers of renal disease in the rat, the change of PIIIP (aminoterminal procollagen III peptide) in serum and hydroxyproline levels in the renal tissue that reflect the synthesis of extracellular matrix (ECM) during development of experimental renal diseases were observed. Two types of experimental primary diseases, diabetes mellitus administrated by streptozotocin (STZ, 75 mg/kg, i.p.) and liver cirrhosis produced by bile duct ligation/scission (BDL/s) operation, were induced. The hydroxyproline level increased according to the high PIIIP and NCl(carboxyterminal procollagen IV peptide) in Western blot analysis as early as 1 week in the STZ treated-rat kidney. Increased renal ECM was observed at 15 weeks in STZ and BDL/s model under the microscopic examination. High PAS positive reaction was found in capillary basement membrane in STZ treated-rats and mesangium in BDL/s operated rats at this time, showing the histological characteristics of diabetic nephropathy and cirrhotic glomerulonephritis in human, respectively. Such secondary renal failure were supported by additional tests including urinalysis and renal function test. The serum PIIIP detected by ELISA was a useful parameter to estimate synthesis rate of renal ECM during development of renal disease without extrarenal fibrosis i.e. liver cirrhosis in rats. This study is proposed that STZ treatment or BDL/s operation may be a suitable experimental animal model for the induction and development of chronic secondary renal diseases. Morover, it was found that hydroxyproline level in renal tissues was a good parameter of the change of renal ECM at the early stage of the diseases without apparent histological changes. Especially, serum PIIIP could be a choice as a diagnostic or prognostic marker during the development of renal diseases in rats.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.31 no.2
• /
• pp.66-70
• /
• 2020

Background and Objectives Presbyphonia is characterized by hoarse, breathy, weak vocal intensity. Extracellular matrix (ECM) in lamina propria (LP) of the vocal folds play an important role in voice production, and change of ECM according to the aging leads to the presbyphonia. The aim of this study was to investigate the histologic analysis of aging vocal fold of rat. Materials and Method Six and twenty two months old Sprague-Dawley rats (n=8, each group) were used and classified into young (six months old rats) and old (twenty two months old rats) group. Histologic analysis and immunohistochemical staining for ECM of LP were performed. Results Overall cellular density was significantly decreased in old rat group. Elastin fibers of LP were significantly decreased in old rat group. Type I collagen was significantly increased in old rat group. Type III collagen did not show significant difference. Hyaluronic acids did not show significant difference in Alcian blue staining and immunohistochemical staining. Conclusion Decreased general cellular density and elastin fiber and increased type I collagen were observed in the LP of vocal folds of aging rats. These ECM changes might to contribute the aging voice.

• Journal of Ginseng Research
• /
• v.46 no.5
• /
• pp.646-656
• /
• 2022

Background: In addition to its use as a health food, ginseng is used in cosmetics and shampoo because of its extensive health benefits. The ginsenoside, Rh2, is a component of ginseng that inhibits tumor cell proliferation and differentiation, promotes insulin secretion, improves insulin sensitivity, and shows antioxidant effects. Methods: The effects of Rh2 on cell survival, extracellular matrix (ECM) protein expression, and cell differentiation were examined. The antioxidant effects of Rh2 in UV-irradiated normal human dermal fibroblast (NHDF) cells were also examined. The effects of Rh2 on mitochondrial function, morphology, and mitophagy were investigated in UV-irradiated NHDF cells. Results: Rh2 treatment promoted the proliferation of NHDF cells. Additionally, Rh2 increased the expression levels of ECM proteins and growth-associated immediate-early genes in ultraviolet (UV)-irradiated NHDF cells. Rh2 also affected antioxidant protein expression and increased total antioxidant capacity. Furthermore, treatment with Rh2 ameliorated the changes in mitochondrial morphology, induced the recovery of mitochondrial function, and inhibited the initiation of mitophagy in UV-irradiated NHDF cells. Conclusion: Rh2 inhibits mitophagy and reinstates mitochondrial ATP production and membrane potential in NHDF cells damaged by UV exposure, leading to the recovery of ECM, cell proliferation, and antioxidant capacity.

• The Korean Journal of Franchise Management
• /
• v.1 no.1
• /
• pp.105-131
• /
• 2010

This practical study is to propose a model for efficiently implementing franchise management by Franchise Enterprise in franchise industry. Franchise system is established and mutual relationship is also fulfilled based on bilateral contract between franchisor and franchisee. After contract and opening the franchisee store, franchisees are continually supervised and administered according to mutually agreed process and procedures. In this regard, franchisor should have well-managed system for supervising and assisting franchisee efficiently and effectively. The purpose of this study is to set-up the concept of enterprise contract management(ECM) in Franchise Enterprise and to promote the systemization of franchise management, and also to present and propose the development tool for franchise-specific IT program which is called " Franchise Contract Management'Supervising System".