• Title/Summary/Keyword: EC Strategy

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Implications of Liver-Directed Therapy for Postoperative Hepatic Metastasis from Esophageal Cancer

  • Urabe, Masayuki;Yagi, Koichi;Shiomi, Shinichiro;Toriumi, Tetsuro;Okumura, Yasuhiro;Setoa, Yasuyuki
    • Journal of Chest Surgery
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    • v.55 no.5
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    • pp.397-404
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    • 2022
  • Background: Distant recurrence of esophageal cancer (EC), even after radical resection, is common, and the most frequent site of EC metastasis is the liver. However, a multidisciplinary treatment strategy for postoperative liver metastasis (LM) from EC has yet to be established; in particular, the role of liver-directed therapy (LDT) remains uncertain. We investigated the clinicopathological features and outcomes of patients undergoing post-esophagectomy LM with versus without LDT to explore its therapeutic implications. Methods: Among 624 consecutive patients undergoing R0/R1 esophagectomy for EC, 30 were identified in whom LM had developed as the initial recurrence. Their characteristics were retrospectively reviewed. Results: Six of the 30 subjects underwent LDT for metachronous LM. Five of those 6 also received systemic chemotherapy. A comparison between the 6 LDT and 24 non-LDT cases revealed no significant differences in major clinicopathological and operative factors, except for concurrent metastasis to extrahepatic organs (1/6 vs. 15/24, p=0.044). Twenty-nine of the 30 patients died during the study period, whereas 1 who had received multimodal treatment with LDT remained alive more than 200 months after multiple LM had been detected. Kaplan-Meier analysis for survival after LM demonstrated significantly prolonged survival in LDT cases compared to non-LDT cases treated with systemic chemotherapy alone (p=0.014). Even when the analysis was limited to patients without extrahepatic metastasis, this significant prognostic advantage of LDT was maintained (p=0.047). Conclusion: Multimodal treatment combined with LDT might be beneficial for patients with metachronous LM from EC and should therefore be considered a potential treatment option.

Technology Development Trends of Self-Powered Next Generation Smart Windows (PV 일체형 차세대 스마트 윈도우 기술개발 동향)

  • Pyun, Sun Ho
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.28 no.12
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    • pp.753-764
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    • 2015
  • Among several types of energy saving smart window technologies, the leader, the dynamic EC (electrochromic) window one needs integrated PV (photovoltaics), to minimize expensive electrical wiring as well as to obviate the need for external energy. Self-powered smart windows were reviewed according to PV types used. DSSCs (dye sensitized solar cells) were found to be compatible with EC cells, to have several categories of next generation smart windows such as PECCs (photoelectrochromic cells), PVCCs (photovoltachromic cells), EC polymer PECCs. In addition silicon solar cells and third generation solar cells were investigated. They are summarized in a table showing their advantages and disadvantages respectively for a fast comparison. The strategy to expedite the commercialization of these next generation smart windows includes developing retrofit smart window coverings for use on flexible polymer substrates adhered to the inside surface of a window and easily replaced after use for upto 10 years.

Factors That Enable Reintermediation

  • Kwon, Sun-Ok;Lee, Hong-Kyu
    • 한국경영정보학회:학술대회논문집
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    • 2007.06a
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    • pp.378-381
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    • 2007
  • Traditional intermediaries refer to service providers such as travel agents, real estate brokers, job agencies and insurance agents which matching services for buyers and suppliers in a traditional market. The introduction of Electronic commerce resulted in the automation of many tasks provided by intermediaries and seemed to eliminate the role of many traditional intermediaries, which is called disintermediation. However, depending on their market power, traditional intermediaries either will be disintermediated or fill new roles by providing added value and assistance, which is called reintermediation. According to the research of Alina M. Chircu et al. there are three conditions for reintermediation for traditional intermediaries. Three conditions are weak appropriability of EC innovations, ownership of co-specialized assets for both market intermediation and EC innovations and economies of scale. Besides these three reintermediation conditions, we hypothesize that leveraging BPO can be a suitable strategy for traditional intermediaries to be transformed into reintermediaries. Business Process Outsourcing (BPO) is the leveraging of technology or specialist process vendors to provide and manage an organization's critical and/or non-critical enterprise processes and applications. This paper will investigate the relationship between above reintermediation conditions including BPO and reintermediation.

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A New Latent Class Model for Analysis of Purchasing and Browsing Histories on EC Sites

  • Goto, Masayuki;Mikawa, Kenta;Hirasawa, Shigeichi;Kobayashi, Manabu;Suko, Tota;Horii, Shunsuke
    • Industrial Engineering and Management Systems
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    • v.14 no.4
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    • pp.335-346
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    • 2015
  • The electronic commerce site (EC site) has become an important marketing channel where consumers can purchase many kinds of products; their access logs, including purchase records and browsing histories, are saved in the EC sites' databases. These log data can be utilized for the purpose of web marketing. The customers who purchase many product items are good customers, whereas the other customers, who do not purchase many items, must not be good customers even if they browse many items. If the attributes of good customers and those of other customers are clarified, such information is valuable as input for making a new marketing strategy. Regarding the product items, the characteristics of good items that are bought by many users are valuable information. It is necessary to construct a method to efficiently analyze such characteristics. This paper proposes a new latent class model to analyze both purchasing and browsing histories to make latent item and user clusters. By applying the proposal, an example of data analysis on an EC site is demonstrated. Through the clusters obtained by the proposed latent class model and the classification rule by the decision tree model, new findings are extracted from the data of purchasing and browsing histories.

Evaluation of Susceptibility to 10 kinds of Acaricides Against Two-Spotted Spider Mites (Tetranychus urticae) in Hooker Chives (삼채에 발생하는 점박이응애에 대한 10종의 살비제 감수성 평가)

  • Kang, Juwan;Kim, Chihyun;Shin, Hocheol;Lee, Gunsik;Kim, Taehwa;Park, Jung-Joon
    • Korean journal of applied entomology
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    • v.59 no.4
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    • pp.399-405
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    • 2020
  • The susceptibility and control efficacy evaluated for 10 kinds of commercialized acaricides, to obtain basic data for the chemical control strategy of Two-spotted spider mite (Tetranychus urticae) in Hooker chives. The susceptibility evaluation of T. urticae female adults, Abamectin EC, Pyflubumide SC, Cyenopyrafen SC, and Acequinocyl SC showed 100% mortality, and Pyflubumide SC, Acequinocyl SC, and Etoxazole SC showed zero hatching rate, i.e. 100% mortality of eggs. As a result of evaluating the field test for Abamectin EC, Pyflubumide SC, Cyenopyrafen SC, Cyflumetofen SC, and Acequinocyl SC, which had excellent mortality in the laboratory conditions, all treatment plots showed more than 90.3% control efficiency on after 7 days.

Disparity-based Error Concealment for Stereoscopic Images with Superpixel Segmentation

  • Zhang, Yizhang;Tang, Guijin;Liu, Xiaohua;Sun, Changming
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.12 no.9
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    • pp.4375-4388
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    • 2018
  • To solve the problem of transmission errors in stereoscopic images, this paper proposes a novel error concealment (EC) method using superpixel segmentation and adaptive disparity selection (SSADS). Our algorithm consists of two steps. The first step is disparity estimation for each pixel in a reference image. In this step, the numbers of superpixel segmentation labels of stereoscopic images are used as a new constraint for disparity matching to reduce the effect of mismatching. The second step is disparity selection for a lost block. In this step, a strategy based on boundary smoothness is proposed to adaptively select the optimal disparity which is used for error concealment. Experimental results demonstrate that compared with other methods, the proposed method has significant advantages in both objective and subjective quality assessment.

Optimum Sewage Discharge Strategy for Coastal Waters

  • Kang, Yun-Ho;Lee, Moon-Ock
    • Environmental Sciences Bulletin of The Korean Environmental Sciences Society
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    • v.10 no.S_3
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    • pp.97-106
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    • 2001
  • To improve the water quality, particularly for sea bathers, the behaviour of wastewater from sewage outfalls in water adjacent to Swansea, UK, was studied using a mathematical model. The water quality in the sewage receiving basin was determined using factors like the outfall diffuser location(distance from land boundary), sewage treatment scheme, discharge time, and bacteria decay rate, etc. With respect to these factors, an optimal strategy for sewage discharge was then investigated to minimize bacteria levels along the bathing beaches. As water quality criteria, predicted faecal coliform levels were monitored along the coast adjacent to the outfall locations. The resultant values were compared with EC Mandatory(<2000, 95 % of 20 samples) and Guideline Standards(< 100, 80 % of 20 samples). For the advective-diffusion equation, the non linear advective terms were represented using the ULTIMATE algorithm and the third-order accurate QUICKEST scheme to avoid numerical diffusion. Details of the simulation results are then presented as an optimal policy for sewage discharge in the region.

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Establishment of Discriminating Concentration based Assessment for Insecticide Resistance Monitoring of Palm thrips (오이총채벌레의 약제 저항성 진단을 위한 판별농도 기반 생물검정법 확립)

  • Jeon, Sung-Wook;Park, Bueyong;Park, Se-Keun;Lee, Sang-Ku;Ryu, Hyun-Ju;Lee, Sang-Bum;Jeong, In-Hong
    • Korean Journal of Environmental Biology
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    • v.35 no.4
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    • pp.557-565
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    • 2017
  • For our survey of insecticidal resistance of Palm thrips (Thrips palmi Karny), we established the discriminating time (DT) and concentration (DC) of nine insecticides, and we conducted a bioassay about seven local populations via leaf-dipping methods. The discriminating times of the recommended concentration (RC) were 24 h at emamectin benzoate EC and spinetoram SC, 48 h at chlorfenapyr EC, 72 h at spinosad SC, cyantraniliprole EC, acetamiprid WP, dinotefuran WG, imidacloprid WP and thiacloprid SC after treatment. The DC estimated the concentration which showed the difference within the mortalities of these local populations. The DCs were emamectin benzoate EC $0.013mg\;L^{-1}$ (RC, $10.8mg\;L^{-1}$), spinetoram SC $0.125mg\;L^{-1}$ (RC, $25.0mg\;L^{-1}$), chlorfenapyr EC $0.25mg\;L^{-1}$ (RC, $50.0mg\;L^{-1}$), spinosad SC $0.083mg\;L^{-1}$ (RC, $50.0mg\;L^{-1}$) and cyantraniliprole EC $5.0mg\;L^{-1}$ (RC, $50.0mg\;L^{-1}$), and DCs of neonicotinoids were their RCs, that is, acetamiprid WP (RC, $40.0mg\;L^{-1}$), dinotefuran WG (RC, $20.0mg\;L^{-1}$), imidacloprid WP(RC, $50.0mg\;L^{-1}$) and thiacloprid SC (RC, $50.0mg\;L^{-1}$). From our investigation into the resistance of the local populations with DT and DC application, the neonicotinoid insecticides have shown a high resistant level for all the local populations, and the other insecticides have demonstrated low or non-resistance. In the use of neonicotinoid insecticides to control Palm thrips, one must take caution. As a result, the establishment of DT and DC in the single dose bioassay method was helpful for surveying the insecticide response dynamics and the development of an insecticide resistance management strategy.

A Study on the EU Regulation for Reducing CO2 from New Passenger Cars to Prevent Climate Change (지구기후변화 방지를 위한 유럽연합(EU) "신규 승용차 이산화탄소 배출 감축 규칙"에 대한 고찰)

  • Park, Myong Sop;Han, Nak Hyun;Kim, Sang Man
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.63
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    • pp.159-184
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    • 2014
  • Climate change is one of the biggest dangers facing all living creatures in the earth. It has been understood that emissions of greenhouse gases from human activity is the cause of climate change. Cars are responsible for around 12% of total EU emissions of CO2, the main greenhouse gas. The United Nations Framework Convention on Climate Change (UNFCCC or FCCC) is an international environmental treaty adopted at the United Nations Conference on Environment and Development (UNCED) on 9 May, 1992, which entered into force on 21 March 1994. The European Commission first adopted a Community Strategy to reduce CO2 emissions from cars in 1995. On 19 December 2007, the European Commission proposed "Proposal for Setting emission performance standards for new passenger cars to reduce CO2 emissions", which was adopted on 23 April 2009 as "Regulation (EC) No 443/2009". Prior to submitting the Proposal, the European Commission performed impact assessment and prepared impact assessment report which was reviewed by the Impact Assessment Board. The objective of this Regulation is to set emission performance standards for new passenger cars registered in the Community, which forms part of the Community's integrated approach to reducing CO2 emissions from light-duty vehicles while ensuring the proper functioning of the internal market. In the event that a manufacturer fails to meet its target, it will be required to pay an excess emissions premium in respect of each calendar year from 2012 onwards. On 11 March 2014, Regulation (EC) No 333/2014 amending Regulation (EC) No 443/2009 was adopted. Regulation (EC) No 333/2014 amends Regulation (EC) No 443/2009 to implement the modalities of meeting the 95g CO2/km target for new passenger cars to be reached in 2020. As industry benefits from indications of the regulatory regime that would apply beyond 2020, the Regulation includes a further review to take place by, at the latest, 31 December 2014.

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A Field Study on Electrokinetic Removal of Salts from Greenhouse Soil (전기동력학 기술을 이용한 시설재배지 토양 염류제거 실증 연구)

  • Lee, You-Jin;Choi, Jeong-Hee;Sim, Seong-Ju;Ha, Tae-Hyun;Lee, Hyun-Goo
    • Korean Chemical Engineering Research
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    • v.52 no.1
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    • pp.126-132
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    • 2014
  • A pilot-scale electrokinetic (EK) separation field test ($2{\times}3{\times}0.2m^3$, $W{\times}L{\times}D$) was performed in a greenhouse to remove salts from saline soil. Initially, the greenhouse soil had high electrical conductivity (EC), about 9 dS/m, and contained mainly $Ca^{2+}$, $Cl^-$ and $SO_4^{2-}$ ions. After 2 weeks of EK treatment, the soil EC was reduced to 52% compared with its initial value. The EC reduction was mostly achieved within the first week (47%) due to removal of $Na^+$ and $Cl^-$ ions, but ions with a high adsorption capacity such as $Ca^{2+}$ and $SO_4^{2-}$ ions were difficult to be removed. During the EK test, the soil temperature increased and it reached around $50^{\circ}C$ at some regions. For in situ application to soils in cultivation, the current should be controlled to limit increases in temperature, especially near the cathodes. In conclusion, the in situ EK technique is feasible for the restoration of saline greenhouse soils in or no cultivation and an appropriate strategy is necessary for more effective remediation.