• Title/Summary/Keyword: EA-INDEX

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Discoloration and the Effect of Antioxidants on Thermo-Oxidative Degradation of Polyamide 6 (폴리아미드 6의 열 산화반응에 의한 황변 현상과 산화방지제의 효과)

  • ;;;T. Mori
    • Polymer(Korea)
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    • v.26 no.4
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    • pp.452-461
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    • 2002
  • In this study, the effect of various concentrations of antioxidants on thermo-oxidative degradation of polyamide 6 was investigated. Unstabilized and stabilized polyamides 6 were subjected to long-term oven aging in ambient atmosphere at 70~$160^{\circ}C$. All of specimens were discolored within 100 hr at temperature range of 70~$160^{\circ}C$. Optimum antioxidant concentration was determined from the data of mechanical properties, yellowness index and relative viscosity. The synergistic effect of each primary and secondary antioxidant concentrations was not observed. Yellowing phenomenon was explained by using NMR, IR and EA. Different carbonyl groups were detected by $^{13}C$/NMR. During thermooxidative degradation, oxygen consumptions were determined by EA. The lifetime after long-term aging was predicted using Arrhenius equation.

Influence of Transcutaneous Electrical Nerve Stimulation and Electroacupuncture on C-fos Expression in Spinal Cord and Functional Recovery After Rat Sciatic Nerve Crush Injury (경피신경전기자극과 전침자극이 흰쥐 좌골신경 압좌손상 후 척수내 c-fos 발현과 기능회복에 미치는 영향)

  • Lee, Hyun-Min
    • The Journal of the Korea Contents Association
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    • v.9 no.6
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    • pp.187-195
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    • 2009
  • The purpose of this study was to identify the effect of transcutaneous electrical nerve stimulation(TENS) and electroacupuncture(EA) after sciatic nerve crush injury in rats. Subjects were classified TENS group with TENS application, EA group with EA application and Control group which is not applicated electrical stimulation. TENS and EA stimulations were applied post-injury day(PD) 1 to 14 after sciatic nerve injury. This study observed c-fos expression in rat lumbar spinal cord. In addition, the paw withdrawal latency(PWL) and sciatic function index(SFI) were measured. The results were as follows: At PD 1, control group had higher c-fos immunoreactivity than experimental groups. At PD 7 and 14, control group had higher c-fos immunoreactivity than experimental groups. The PWL of experimental groups were significantly lower than control group. The SFI had not significant difference in all groups. But the average of experimental groups were higher than control group. These results suggest that TENS and EA applications increasing sensory and motor nerve recovery while decreasing c-fos immunoreactivity after sciatic nerve crush injury.

ea­-RED++: Adding Prediction Algorithm for ea­-RED Router Buffer Management Algorithm (ea-­RED++ : 예측 알고리즘을 적용한 ea-­RED 알고리즘)

  • Lee, Jong-Hyun;Lim, Hye-Young;Hwang, Jun;Kim, Young-Chan
    • Proceedings of the Korean Information Science Society Conference
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    • 2003.10c
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    • pp.298-300
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    • 2003
  • ea­RED(Efficient Adaptive RED)[1][2]는 다수의 TCP 커넥션이 경쟁하는 병목구간에서 인터넷 라우터 버퍼를 능동적으로 관리하는 다양한 AQM(Active Queue Management) 알고리즘 중의 하나로 RED 라우터 버퍼 관리 알고리즘의 성능을 개선한 라우터 버퍼 관리 알고리즘이다. RED 라우터가 TD 라우터와 같은 네트워크 퍼포먼스를 유지하면서 TCP 커넥션 간 페어니스를 향상시키기 위해서는 link bandwidth. active 커넥션 수. congestion level 등에 대한 네트워크 상태를 고려하여 파라미터에 적절한 값을 설정해야만 한다. 문제는 다이내믹하게 변하는 네트워크 상황에 적합한 파라미터 값을 초기에 설정해주는 것이 매우 어렵다는 점이다. [3]. ea­RED는 max threshold와 min threshold 값을 네트워크 상황에 따라 동적으로 조절함으로써 이런 문제를 해결했고, 기존 RED에 비해 라우터 버퍼는 50% 정도만 사용하면서도, 페어니스 인덱스(Fairness Index)[4]가 최대 41.42% 개선되었다. [1] [2] 그러나 송신 TCP 커넥션의 수가 늘어날수록 성능향상에 대한 효과가 감소되었고, 드롭 패킷수가 TD나 RED 라우터 버퍼관리 알고리즘에 비해 많았기 때문에 라우터의 출력(output) 총 패킷 용량이 최대 약 2.3% 정도 TD나 RED 라우터 버퍼관리 알고리즘에 비해 적었다. 이 부분을 개선하기 위해 기존 ea­RED 알고리즘에 LR_Lines 예측 알고리즘을 적용한 ea­RED++ 알고리즘을 구현하였고, 실험 결과 페어니스 인덱스는 기존 ea­RED에 비해 최대 약 30% 정도 향상되었고, 총 output 패킷 용량의 손실률은 최대 50%정도 감소하여 기존 ea­RED에 비해 향상된 성능을 보여주었다.웍스 네트워크상의 다양한 디바이스들간의 네트워크 다양화와 분산화 기능을 얻을 수 있었고, 기존의 고가의 해외 솔루션인 Echelon사의 LonMaker 소프트웨어를 사용하지 않고도 국내의 순수 솔루션인 리눅스 기반의 LonWare 3.0 다중 바인딩 기능을 통해 저 비용으로 홈 네트워크 구성 관리 서버 시스템 개발에 대한 비용을 줄일 수 있다. 기대된다.e 함량이 대체로 높게 나타났다. 점미가 수가용성분에서 goucose대비 용출함량이 고르게 나타나는 경향을 보였고 흑미는 알칼리가용분에서 glucose가 상당량(0.68%) 포함되고 있음을 보여주었고 arabinose(0.68%), xylose(0.05%)도 다른 종류에 비해서 다량 함유한 것으로 나타났다. 흑미는 총식이섬유 함량이 높고 pectic substances, hemicellulose, uronic acid 함량이 높아서 콜레스테롤 저하 등의 효과가 기대되며 고섬유식품으로서 조리 특성 연구가 필요한 것으로 사료된다.리하였다. 얻어진 소견(所見)은 다음과 같았다. 1. 모년령(母年齡), 임신회수(姙娠回數), 임신기간(姙娠其間), 출산시체중등(出産時體重等)의 제요인(諸要因)은 주산기사망(周産基死亡)에 대(對)하여 통계적(統計的)으로 유의(有意)한 영향을 미치고 있어 $25{\sim}29$세(歲)의 연령군에서, 2번째 임신과 2번째의 출산에서 그리고 만삭의 임신 기간에, 출산시체중(出産時體重) $3.50{\sim}3.99kg$사이의 아이에서 그 주산기사망률(周産基死亡率)이 각각 가장 낮았다. 2. 사산(死産)과 초생아사망(初生兒死亡)을 구분(區分)하여 고려해 볼때 사산(死産)은 모성(母性)의 임신력(姙娠歷)과 매우 밀접한 관련이 있는 것으로 사료(思料)되었고 초생아사망(初生兒死亡)은 미숙아(未熟兒)와 이에 관련된 병

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Comparison of the Dose Distributions with Beam Arrangements in the Stereotactic Body Radiotherapy (SBRT) for Primary Lung Cancer (원발성 폐암에서 정위적 체부 방사선치료의 빔 배열에 따른 선량분포의 비교)

  • Yea, Ji Woon
    • Progress in Medical Physics
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    • v.25 no.2
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    • pp.110-115
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    • 2014
  • To compare 2 beam arrangements, circumferential equally angles (EA) beams or partially angles (PA) beams for stereotactic body radiation therapy (SBRT) of primary lung cancer for intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) delivery techniques with respect to target, ipsilateral lung, contralateral lung, and organs-at-risk (OAR) dose-volume metrics, as well as treatment delivery efficiency. Data from 12 patients, four treatment plans were generated per data sets ($IMRT_{EA}$, $IMRT_{PA}$, $VMAT_{EA}$, $VMAT_{PA}$). The prescribed dose (PD) was 60 Gy in 4 fractions to 95% of the planning target volume (PTV) for a 6-MV photon beam. When compared with the IMRT and VMAT treatment plan for 2 beams, conformity index, homogeneity index, high dose spillage, D2 cm (Dmax at a distance ${\geq}2cm$ beyond the PTV), R50 (ratio of volume circumscribed by the 50% isodose line and the PTV), resulted in similar. But Dmax of the Organ at risk (OAR), spinal cord, trachea, resulted in differ between four treatment plans. Especially $HDS_{location}$ showed big difference in 21.63% vs. 26.46%.

Antimicrobial Activity of Elfvingia applanata Extract Alone and in Combination with Naringenin (Elfvingia applanata 엑스의 항균력 및 Naringenin과의 병용효과)

  • Cheon, Jun-Hee;Lee, Sun-Ok;Rym, Kyo-Hwan;Eo, Seong-Kug;Lee, Chong-Kil;Han, Seong-Sun
    • The Korean Journal of Mycology
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    • v.23 no.2 s.73
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    • pp.153-160
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    • 1995
  • As part of our search for less toxic antimicrobial agents from natural resources, the antimicrobial activity of Elfvingia applanata $(P_{ers.})\;K_{arst.}$ extract was examined alone and in combination with naringenin. EA, the aqueous extract from the carpophores of E. applanata, was lyophilized and a dark brownish powder was obtained. Antimicrobial activity of EA was tested in vitro against nineteen strains of bacteria and eleven strains of fungi by serial broth dilution method, and expressed by minimal inhibitory concentration (MIC). Among nineteen strains of bacteria tested, the antimicrobial activity of EA was the most potent against Proteus vulgaris showing MIC of 1.125 mg/ml. EA also inhibited the growth of the selected fungi at higher concentrations ranging from 7.5 mg/ml to 15.0 mg/ml. To investigate the effect of antimicrobial combinations of EA with naringenin, the fractional inhibitory concentration index (FICI) was determined by checkerboard assay for each strain. The antimicrobial combinations of EA with naringenin resulted in partial synergism against Staphylococcus aureus only, and showed additive effect in two strains including Klebsiella pneumoniae and Salmonella typhi. Antagonism was not found.

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A Study on the Effects of the Electro-Acupuncture(EA) Stimulation after Global Ischemia(GI) on Changes in Bax and Caspase-3 Expression among Forebrain Apoptosis (뇌허혈 유발 후 전침자극이 전뇌세포사 중 Bax와 Caspase-3 발현 변화에 미치는 영향 연구)

  • Choi, Jung-Hyun;Min, Kyoung-Ok;Kim, Soon-Hee;Kim, Dong-Il;Lee, Sang-Bin;An, Ho-Jung;Kim, Ji-Sung;Choi, Wan-Suk;Kim, Bo-Kyoung;Song, Chi-Won
    • Journal of Oriental Neuropsychiatry
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    • v.21 no.1
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    • pp.59-69
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    • 2010
  • Objectives: The study aims to look into how the application of EA(Electro-acupuncture) in the initial step of ischemic brain injury affects the changes in Bax and Caspase-3 expression among forebrain apoptosis. Methods: It caused GI by using common carotid artery occlusion and conducted the test by dividing into the no applied EA group after 6 hours and 12 hours, the LI 4 EA group that applied EA to LI4, and GV 20 EA group that was applied to GV 20. After that, the following results were obtained by comparing Bax and Caspase-3 expression, which were apoptosis-related factors, with its application time through immunohistochemical staining after extracting brain of each group. Results: According to each group's Bax expression by the application time, the order of expression increase after 6 hours is shown to be the no applied EA group, LI 4 group, and GV 20 group. The stimulation after 12 hours was most lowly expressed in the GV 20 group, and the no applied EA group and LI 4 group showed similar level. Conclusions: EA stimulation in the initial step after ischemia seems to affect positively Bax and Caspase-3 expression that are index of forebrain apoptosis.

$\alpha_2$-Adrenoceptors are Implicated in the Electroacupuncture-induced Analgesia of Experimental Chronic Pain (전침자극이 만성통증을 억제하는 아드레날린성 기전에 대한 연구)

  • Shin Hong-Kee;Lee Kyung-Hee;Park Dong-Suk
    • The Journal of Korean Medicine
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    • v.25 no.3
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    • pp.67-77
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    • 2004
  • Objectives : Many studies have reported that acupuncture analgesia was mediated through the activation of peripheral and central opioid receptors. However, there has been little electrophysiological study on the adrenergic mechanism of acupuncture analgesia in chronic inflammatory and neuropathic pain. The present study was undertaken to elucidate the role of adrenoceptors in the production of acupuncture analgesia in the chronic pain model. Methods : In the rat with chronic inflammation and nerve injury, dorsal horn cell (DHC) responses to afferent C fiber stimulation were used as a pain index and changes in electroacupuncture (EA) analgesia were recorded before and after intravenous administration of selective adrenoceptor antagonists. EA stimulations (2Hz, 0.5msec, 3mA) were applied to the contralateral Zusanli point for 30 min. Results : EA stimulation induced long-lasting inhibition of DHC responses in the rat with chronic inflammation and nerve injury. In both models of inflammation and neuropathic pain, α-adrenoceptor antagonist (phentolamine) significantly attenuated an inhibitory effect of EA on DHC responses. Selective α2-adrenoceptor antagonist (yohimbine) also had a similar suppressive action on DHC responses to that of phentolamine. However, β-adrenoceptor antagonist (propranolol) did not have any inhibitory effect on DHC responses in either model of chronic pain. Conclusions : These experimental findings suggest that in rats with chronic pain, EA stimulation with low frequency and high intensity produced an analgesic effect which was mediated through an activation of α2-adrenoceptors.

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Mother-Child Emotional Availability Mediating the Effects of Maternal Psychological Well-being and Child's Cognitive Competence on Child Behavior Problems

  • Kang, Min-Ju
    • International Journal of Human Ecology
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    • v.12 no.2
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    • pp.95-107
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    • 2011
  • Recent intervention studies document that mother-child dyads with higher levels of Emotional Availability (EA) report fewer child behavior problems than dyads with lower EA. This study examines possible mechanisms that lead to this result by looking at the parent-child micro-system as a whole, with multi-dimensional relationships that include individual differences in the child's cognitive level, parental stress and parent-child interaction. A total 67 children ($1{\frac{1}{2}}$ to $5\;{\frac{1}{2}}$ years of age) and their mothers were videotaped during 30-min play interactions. Interactions were coded using the Emotional Availability (EA) Scales (Biringen, Robinson, & Emde, 1998). Mothers completed Parenting Stress Index-Short Form, Child Behavior Checklist/$1\;{\frac{1}{2}}$ - 5, and the Ages Stages Questionnaire. The findings showed that mothers with higher levels of parenting stress were more likely to be intrusive, hostile, insensitive, and had a tendency to do less structuring in play. The children of stressed and depressed mothers demonstrated less involvement and responsiveness towards their mothers. Children who have higher dyadic EA scores experienced fewer externalizing and internalizing problems. SEM analyses results showed a mediation effect of EA on the association between maternal psychological well-being and child behavior problems. Fewer deficits in child communication skills and problem solving skills that were related with lower parenting stress and depression were associated with higher maternal non-intrusiveness. Higher non-intrusiveness was related to less internalizing and externalizing problems that indicated the indirect effect of child cognitive competence. Possible interpretations and implications of the study findings are discussed.

Attenuation of Brain Injury by Water Extract of Goat's-beard (Aruncus dioicus) and Its Ethyl Acetate Fraction in a Rat Model of Ischemia-Reperfusion

  • Han, Hyung-Soo;Lee, Jong-Won
    • Preventive Nutrition and Food Science
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    • v.16 no.3
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    • pp.217-223
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    • 2011
  • Ischemic stroke constitutes about 80% of all stroke incidences. It is characterized by brain cell death in a region where cerebral arteries supplying blood are occluded. Under these ischemic conditions, apoptosis is responsible for the cell death, at least in part. Goat's-beard (Aruncus dioicus var. kamtschaticus) is a perennial plant that grows naturally in the alpine regions of Korea. In the present study, we first determined whether water extract of goat's-beard (HY1646) and some of its fractions prepared by partitioning with organic solvents could improve the viability of human hepatocellular carcinoma cells (HepG2) cultured under hypoxic condition by blocking apoptotic pathways. Based on the in vitro findings, we subsequently investigated whether HY1646 and the ethyl acetate fraction (EA) selected from cell culture-based screening could attenuate brain injury in a rat middle cerebral artery occlusion (MCAO) model of ischemia (2 hr), followed by 22 hours of reperfusion. The cell number was sustained close to that initially plated in the presence of HY1646 even after 24 hr of cell culture under hypoxic condition (3% $O_2$), at which time the cell number reached almost zero in the absence of HY1646. This improvement in cell viability was attributed to the delay in apoptosis, identified by the formation of DNA ladder in gel electrophoresis. Of fractions soluble in hexane, ethyl acetate (EA) and butanol, EA was chosen for the animal experiments because EA demonstrated the best cell viability at the lowest concentration (10 ${\mu}g$/mL). HY1646 (200 mg/kg) and EA (10 and 20 mg/kg) significantly reduced infarct size, an index of brain injury, by 16.6, 40.0 and 61.0%, respectively, as assessed by 2,3,5-triphenyl tetrazolium chloride staining. The findings suggest that prophylactic intake of goat's beard might be beneficial for preventing ischemic stroke.

Comparative study on the effects of 2 Hz electroacupuncture stimulation at left and right GB34's in $CCl_4$-intoxicated rats ($CCl_4$로 유도된 흰쥐의 간기능 손상에 대한 좌우 양릉천(陽陵泉) 전침 효과 비교 연구)

  • Yi, Ji-Young;Yang, Gi-Young;Lee, Byung-Ryul;Yim, Yun-Kyung
    • Korean Journal of Acupuncture
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    • v.25 no.4
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    • pp.119-132
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    • 2008
  • Objectives : To compare the effects of low-frequency electro-acupuncture (EA) stimulation at left and right GB34s on hepatotoxicity in $CCl_4$-intoxicated rats. Methods : Rats were injected with $CCl_4$ and treated with 2 Hz electro-acupuncture (EA) at left and right GB34s for 15 minutes 3 times per week, for 10 weeks. Holder group, injected with $CCl_4$ and strained in a cylinder for same period as the EA group, was established to compare the hepatotoxicity against the two electroacupuncture groups. To estimate the effects of EA on hepatotoxicity in rats, body weight, liver weight and liver index were measured. Biochemical assays for serum ALT, AST, ALP and total cholesterol ; hematological analysis for RBC, WBC, PLT, hemoglobin, lymphocytes, neutrophils and monocytes ; and histology analysis of liver tissue were also performed. Results : Lymphocyte level in blood was significantly decreased by $CCl_4$-intoxication, and increased by low-frequency electroacupuncture applied on both left and right GB34s. Low-frequency EA applied on right and left GB34s significantly reduced serum ALT and AST, both of which had been increased by $CCl_4$-intoxication. Conclusion : Low-frequency electroacupunctures at both left and right GB34s have hepatoprotective effects on $CCl_4$-induced liver damage in rats. However, no significant differences were found between the effects of EAs at left and right GB34s.

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