• 대한전자공학회논문지
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• 제26권1호
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• pp.38-47
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• 1989

GaInAs/InP 이종접합(heterojunction)에서의 부밴드 구조(subband structure)를 self-consistent 방법으로구하였다. GaInAs내의 background impurity와 장벽높이 (barrier height 또는 밴드 불연속: band discontinuity)가 에너지 준위(energy level), 페르미 준위(Fermi level)와 점유율(population)등에 미치는 영향을 살펴보기 위하여, background impurity 농도의 경우 $1.0{\times}10^{14},\;1.0{\times}10^{15},\;1.0{\times}10^{16}\;[cm^{-3}]$, 장벽높이는 0.3, 0.53[eV]에 대하여 각각 살펴 보았다. Background impurity 농도가 증가함에 따라 에너지 값이 증가하며 페르미 준위 역시 증가한다. 아울러 첫번째와 두번째 에너지 준위의 차도 증가한다. 에너지 준위에 대한 전자의 점유율은 background impurity의 증가와 함께 큰 값을 나타내지만 두번째 에너지 준위에 대한 점유율은 거의 변하지 않는다. 장벽 높이가 커지면, 에너지 준위와 페르미 준위는 각각 증가하나 에너지 준위차는 거의 변화가 없다. 그런데, 장벽높이가 큰 경우 첫번째 에너지 준위에 대한 전자의 점유율은 ㄱ마소하는 반면 두번째 준위에 대한 점유율이 다소 증가한다.

• BMB Reports
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• 제38권5호
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• pp.624-631
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• 2005

Tuberculosis, caused by Mycobacterium tuberculosis, continues to be one of the main diseases to mankind. It is urgent to discover novel drug targets for appropriate antimicrobial agents against this human pathogen. The shikimate pathway is onsidered as an attractive target for the discovery of novel antibiotics for its essentiality in bacteria and absence in mammalian cells. The Mycobacterium tuberculosis aroE-encoded shikimate dehydrogenase was cloned, expressed and purified. Sequence alignment analysis shows that shikimate dehydrogenase of Mycobacterium tuberculosis exhibit the pattern of G-X-(N/S)-V-(T/S)-X-PX-K, which is highly conserved within the shikimate dehydrogenase family. The recombinant shikimate dehydrogenase spectrum determined by CD spectroscopy showed that the percentages for $\alpha$-helix, $\beta$-sheet, $\beta$-turn, and random coil were 29.2%, 9.3%, 32.7%, and 28.8%, respectively. The enzymatic characterization demonstrates that it appears to be fully active at pH from 9.0 to 12, and temperature $63^{\circ}C$. The apparent Michaelis constant for shikimic acid and $NADP^+$ were calculated to be about $29.5\;{\mu}M$ and $63\;{\mu}M$. The recombinant shikimate dehydrogenase catalyzes the substrate in the presence of $NADP^+$ with an enzyme turnover number of $399\;s^{-1}$. Zymological studies suggest that the cloned shikimate dehydrogenase from M. tuberculosis has a pretty activity, and the work should help in the discovery of enzyme inhibitors and further of possible antimicrobial agents against Mycobacterium tuberculosis.

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1605-1610
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• 2012

Gelam and Nenas monofloral honeys were investigated in this study for their chemopreventive effects against HT 29 colon cancer cells. MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolim) assays showed more effective inhibition of colon cancer cells proliferation by Gelam honey with $IC_{50}$ values of 39.0 mg/ml and 85.5 mg/ml respectively after 24 hours of treatment. Alkali comet assays revealed both honeys increased DNA damage significantly in a dose dependent manner. In addition, annexin V-FITC/PI flow cytometry demonstrated that at $IC_{50}$ concentrations and above, both Gelam and Nenas honeys induced apoptosis significantlyat values higher than for necrosis (p<0.05). Measurement of prostaglandin $E_2$ ($PGE_2$) confirmed that Gelam and Nenas honeys reduced its production in $H_2O_2$ inflammation-induced colon cancer cells. In conclusion, our study indicated and confirmed that both Gelam and Nenas honeys are capable of suppressing the growth of HT 29 colon cancer cells by inducing apoptosis and suppressing inflammation.

• 대한수의학회지
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• 제28권2호
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• pp.261-270
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• 1988

This study was performed to investigate the effect of gestation on the histological and histochemical changes of the uterine cervix of the native Korean cattle. A total of 110 cows obtained from the Chonhuk abattoir were divided into six groups. The 1st group was of 9 non-pregnant cows and 101 singleton pregnant cows were grouped into 5 groups from pregnant I to pregnant V according to gestation periods by means of crown rump length measures. For light microscopy the tissues were fixed in 10% neutral formalin and processed routinely for paraffin sections The $6{\mu}m$ sections were taken and stained with H-E, Alcian blue pH 1.0, Alcian blue pH 2.5, Alcian blue pH 2.5/PAS, PAS reaction, toluidin blue, and trichrome. The results obtained were as follows: 1. The cervical lengths and widths were increased in relation to advancing gestation. 2. The cervical folds of the pregnant groups were increased and complicated with many branches, and the cervical muscosal epithelia were increased in according to advancing gestation. 3. As advancing gestation, the tunics muscularis of cervix was increased following moderate distribution of fibroblast and vascularity, meanwhile decreased mast cells were found. 4. The cervical mucosubstance was composed of mixed mucopolysaccharides; the acid mucus was increased from the early pregnant state but the neutral mucus was found after pregnant IV, and the mucus was stained deeply in each staining in the fold cavity in according to gestation state.

• 한국물환경학회지
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• 제32권6호
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• pp.528-536
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• 2016

The purpose of Total Pollution Load Control at Tributary is to obtain maximum improvement effect of water quality through finding the most impaired section of water-body and establishing the proper control measure of pollutant load. This study was implemented to determine the optimal management of reach, period, condition, watershed, and pollution source and propose appropriate reduction practices using the Load duration curve (LDC) and field monitoring data. With the data of measurement, LDC analysis shows that the most impaired condition is reach V (G4~G5), E group (flow exceedance percentile 90~100%) and winter season. For this reason, winter season and low flow condition should be preferentially considered to restore water quality. The result of pollution analysis for the priority reach and period shows that agricultural nonpoint source loads from onion and garlic culture are most polluting. Therefore, it is concluded that agricultural reuse of surface effluent (storm-water runoff with non-point sources) and low impact farming that includes reducing fertilization and controlling the height of drainage outlet are efficient water quality management for this study watershed.

• Asian-Australasian Journal of Animal Sciences
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• 제30권5호
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• pp.603-621
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• 2017

The current review focuses on characterization and conservation efforts vital for the development of breeding programmes for indigenous beef cattle genetic resources in Southern Africa. Indigenous African cattle breeds were identified and characterized using information from refereed journals, conference papers and research reports. Results of this current review reviewed that smallholder beef cattle production in Southern Africa is extensive and dominated by indigenous beef cattle strains adaptable to the local environment. The breeds include Nguni, Mashona, Tuli, Malawi Zebu, Bovino de Tete, Angoni, Landim, Barotse, Twsana and Ankole. These breeds have important functions ranging from provision of food and income to socio-economic, cultural and ecological roles. They also have adaptive traits ranging from drought tolerant, resistance to ticks and tick borne diseases, heat tolerance and resistance to trypanosomosis. Stakeholders in the conservation of beef cattle were also identified and they included farmers, national government, research institutes and universities as well as breeding companies and societies in Southern Africa. Research efforts made to evaluate threats and opportunities of indigenous beef cattle production systems, assess the contribution of indigenous cattle to household food security and income, genetically and phenotypically characterize and conserve indigenous breeds, and develop breeding programs for smallholder beef production are highlighted. Although smallholder beef cattle production in the smallholder farming systems contributes substantially to household food security and income, their productivity is hindered by several constraints that include high prevalence of diseases and parasites, limited feed availability and poor marketing. The majority of the African cattle populations remain largely uncharacterized although most of the indigenous cattle breeds have been identified.

• 한국대기환경학회지
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• 제32권1호
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• pp.82-99
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• 2016

This study was carried out to understand the regional contribution of Particulate Matter (PM) emissions from East Asia ($82^{\circ}{\sim}149^{\circ}E$, $18^{\circ}{\sim}53^{\circ}N$) to Seoul during high concentration period in February 2014. The Community Multi-scale Air Quality (CMAQ) version 5.0.2 with Decoupled Direct Method (DDM) was used to analyze levels of contributions over Seoul. In order to validate model performance of the CMAQ, predicted PM and its chemical species concentrations were compared to observations in China and Seoul. Model predictions could depict the daily and hourly variations of observed PM. The calculated PM concentrations, however, had a tendency of underestimation. The discrepancies are due to uncertainties of meteorological data, emission inventories and CMAQ model itself. The high PM concentration in Seoul was induced by stationary anticyclone over the West Coast of Korea during 24 to 27 February. The DDM in CMAQ was used to analyze the contributions of emissions from East Asia on Seoul during this PM episode. $PM_{10}$ concentration in Seoul is contributed by 39.77%~53.19% from China industrial and urban region, 15.37%~37.10% from South Korea, and 9.03%~18.05% North Korea. These indicate that $PM_{10}$ concentrations in Seoul during the episode period are dominated by long-range transport from China region as well as domestic sources. It was also found that the largest contribution region in China were Shandong peninsula during the PM event period.

• 한국음향학회지
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• 제13권1호
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• pp.71-83
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• 1994

본 논문은 한국어 문어면환(TTS : Text-to-Speech) 시스템내에서의 음성합성시 음질 및 자연성 개선을 위한 연구 결과이다. 합성방법으로는 단음절단위의 파형을 시간영역에서 분석(표1)하여 규칙합성에 필요한 매개변수(표2)를 추출하여 규칙합성시켰다. 실험에 사용된 음절은 한국어 발음 대사전의 빈도순위에 따라 V형 19개, CV형 80개, VC형 30개, CVC형 100개등 총 229음절을 선정하여 규칙합성시켰다. 규칙합성음의 평가방법으로는 229개의 규칙합성음중 음절 유형별로 15개씩 무작위로 추출한 합성음을 사전지식이 없는 임의의 그룹을 선정하여 이해도, 명료도, 잡음감, 자연성등 4가지 항목에 대하여 주관적인 오피니온 평가를 수행하였다. 실험결과, 합성음의 음질은 대단히 명료한 수준이었으며, 운율요소의 제어결과는 지속시간(장단)과 악센트(강약)의 제어(그림 9, 그림 10)가 가능하였으며, 피치주기(억양)의 제어도 Lagrange 보간법을 사용함으로써 가능하였다(그림 11, 그림 12).

• 통상정보연구
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• 제10권2호
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• pp.325-348
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• 2008

The purpose of this study is to find out the relationship between job fitness, organizational justice(distributive, procedural, interactional), job satisfaction, organizational trust, organizational commitment, and voluntary turnover intention in private organization such as in small fire in Korea. To identify the these relationships, the secondary data or past studies that were related with job fitness, organizational justice, job satisfaction, organizational trust, organizational commitment, voluntary turnover intention was collected and theoretically arranged. I made the theoretical proposed model to explain these relationships between the constructs, identify the operational definitions and 18 hypotheses was established, there was executed the survey of 262 in employees. Using the collected data, previous performances to confirm the construct validity and internal consistency by EFA(Exploratory Factor Analysis); i.e. factor analysis by SPSS, reliability by cronbach's a, and by the CFA(Confirmative Factor Analysis) and structural equations modelling the proposed model was tested by LISREL v. 8.52. The research came to the conclusions as follows: First, three perceived justice had the positive effect to the job satisfaction empirically. Second, procedural justice in three perceived justice only had the positive effect to the organizational trust empirically. Third, distributive justice in three perceived justice only had the positive effect to the organizational commitment empirically. Forth, job fitness had the positive effect to the organizational commitment, organizational trust, job satisfaction empirically in perspective. Fifth, I found the relationship between job satisfaction and organizational commitment, between job satisfaction and organizational trust was positive, between organizational commitment and trust. Finally, job satisfaction, organizational trust had not the positive effect directly, but indirect effect via organizational commitment was identified in voluntary turnover intention by empirical test.

• 한국재료학회:학술대회논문집
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• 한국재료학회 2010년도 춘계학술발표대회
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• pp.54.2-54.2
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• 2010

최근까지는 주로 비정질 실리콘이 디스플레이의 채널층으로 상용화 되어왔다. 비정질 실리콘 기반의 박막 트랜지스터는 제작의 경제성 및 균일성을 가지고 있어서 널리 상용화되고 있다. 하지만 비정질 실리콘의 구조적인 문제인 낮은 전자 이동도(< $1\;cm^2/Vs$)로 인하여 디스플레이의 대면적화에 부적합하며, 광학적으로 불투명한 특성을 갖기 때문에 차세대 디스플레이의 응용에 불리한 점이 있다. 이런 문제점의 대안으로 현재 국내외 여러 연구 그룹에서 산화물 기반의 반도체를 박막 트랜지스터의 채널층으로 사용하려는 연구가 진행중이다. 산화물 기반의 반도체는 밴드갭이 넓어서 광학적으로 투명하고, 상온에서 증착이 가능하며, 비정질 실리콘에 비해 월등히 우수한 이동도를 가짐으로 디스플레이의 대면적화에 유리하다. 특히 Zinc Oxide의 경우, band gap이 3.4eV로써, transparent conductors, varistors, surface acoustic waves, gas sensors, piezoelectric transducers 그리고 UV detectors 등의 많은 응용에 쓰이고 있다. 또한, a-Si TFTs에 비해 ZnO-based TFTs의 경우 우수한 소자 성능과 신뢰성을 나타내며, 대면적 제조시 우수한 균일성 및 낮은 생산비용이 장점이다. 그러나 ZnO-baesd TFTs의 경우 일정한 bias 아래에서 threshold voltage가 이동하는 문제점이 displays의 소자로 적용하는데 매우 중요하고 문제점으로 여겨진다. 특히 gate insulator와 channel layer사이의 interface에서의 defect에 의한 charge trapping이 이러한 문제점들을 야기한다고 보고되어진다. 본 연구에서는 Zinc Oxide 기반의 박막 트랜지스터를 DC magnetron sputtering을 이용하여 상온에서 제작을 하였다. 또한, $Si_3N_4$ 기판 위에 electron cyclotron resonance (ECR) $O_2$ plasma 처리와 plasma-enhanced chemical vapor deposition (PECVD)를 통하여 $SiO_2$ 를 10nm 증착을 하여 interface의 개선을 시도하였다. 그리고 TFTs 소자의 출력 특성 및 전이 특성을 평가를 하였고, 소자의 field effect mobility의 값이 향상을 하였다. 또한 Temperature, Bias Temperature stability의 조건에서 안정성을 평가를 하였다. 이러한 interface treatment는 안정성의 향상을 시킴으로써 대면적 디스플레의 적용에 비정질 실리콘을 대체할 유력한 물질이라고 생각된다.