• BMB Reports
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• v.49 no.8
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• pp.431-436
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• 2016

Human papillomavirus (HPV) is the major cause of cervical cancer, a deadly threat to millions of females. The early oncogene product (E7) of the high-risk HPV16 is the primary agent associated with HPV-related cervical cancers. In order to understand how E7 contributes to the transforming activity, we investigated the structural features of the flexible N-terminal region (46 residues) of E7 by carrying out N-15 heteronuclear NMR experiments and replica exchange molecular dynamics simulations. Several NMR parameters as well as simulation ensemble structures indicate that this intrinsically disordered region of E7 contains two transient (10-20% populated) helical pre-structured motifs that overlap with important target binding moieties such as an E2F-mimic motif and a pRb-binding LXCXE segment. Presence of such target-binding motifs in HPV16 E7 provides a reasonable explanation for its promiscuous target-binding behavior associated with its transforming activity.

• Proceedings of the Korea Association of Information Systems Conference
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• 2005.05a
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• pp.409-424
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• 2005

Today, many universities are confronted with the changing education paradigm such as e-Learning, Distance Education, Virtual University. This IT-based learning paradigm shift is certainly a new opportunity or a threat to our universities. The Local University Community e-Learning Centers that support the demand of e-Learning for their community are recommended. Tn order to operate these centers efficiently, the strategic roles of the e-Learning center should first be defined. To define the strategic roles, We classified the strategic roles of the e-Learning center into four dimensions, (1) to improve management efficiency, (2) to enhance educational service, (3) to acquire competitive advantages, (4) to build new education infrastructure, and each dimension has S or 6 measurement items. As result, to enhance the educational service was considered as the most significant factor among the four dimensions of strategic roles, and the infrastructure building was the next. Through the strategic roles definition and analysis of expected role ratings, we could have recommended the direction and operation policies of the e-Learning centers.

• 대한생식의학회:학술대회논문집
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• 2003.12a
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• pp.123-124
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• 2003

• The Journal of Asian Finance, Economics and Business
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• v.8 no.10
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• pp.129-138
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• 2021

Several studies have revealed that information on borrower characteristics plays an important factor in approving their credit requests. Though the extent to which such characteritics are also applicable to the case of fintech lending remain uncertain. The aim of this study is, thus, to investigate the determinant factors that influence MSEs in obtaining credit through fintech lending. Here, we emphasize virtual trust in fintech lending encompasing the dimension of social network, economic attributes, and risk perception based on several indicators that are used as proxies. Primary data used in the study was gathered from an online survey to the respondents of MSEs in Java. The result of the study indicates that determinants of MSEs in obtaining credit from lender through fintech lending are statistically influenced by internet usage activities, borrowing history, loan utilization, annuity payment system, completeness of credit requirement documents and compatibility of loan size with the business need. These factors have a significant effect on credit approval because they can generate virtual trust of fintech lender to MSEs as potential borrowers. It concludes that the probability of obtaining fintech loans in accordance with their expectations are influenced by the dimensions of social network, economic attributes and risk perception.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.2 no.1
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• pp.65-82
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• 2007

This aim of study is to offer three way(the E-commerce operations site, electronic catalog site, the E- commerce function improvement, the off-line E-biz revitalization) for E-commerce revitalization of business incubator center's resident enterprise through interview with business incubator center's resident enterprise, business incubator center's manager and the operation company of the COBIAN as E-commerce site of business incubator center. Solutions presented by business incubator center are considered from various angles to improve law perception in the COBIAN and to exchange contact information among BI companies in the COBIAN. And The solution emphasize an efficiency as well as an absolute investment to present the solutions that are able to do better important function as business incubator center than any other. furthermore, a business incubator center presents solutions for solving problems with small and medium enterprises as well as the COBIAN, which is doing E-commerce operation.

• 한국생물공학회:학술대회논문집
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• 2005.04a
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• pp.563-563
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• 2005

• Journal of Korea Foundry Society
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• v.27 no.2
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• pp.65-71
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• 2007

• Polymer Science and Technology
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• v.6 no.4
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• pp.314-325
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• 1995

• 한국정보디스플레이학회:학술대회논문집
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• 2009.10a
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• pp.356-359
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• 2009

In recent years, flexible e-paper displays based on electrophorectic materials continue to attract enormous interest from technologists and are expected to be in the market soon. To realize a flexible e-paper, several key technologies for TFT backplane have been developed, while it still lacks good color reproduction and requires input function for use in its various applications. Thus, the technical issues for implementing color and touch functions in a flexible e-paper are discussed, and then our development status along with technology trend of it is described.

• Biotechnology and Bioprocess Engineering:BBE
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• v.4 no.1
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• pp.63-65
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• 1999

Although many pharmaceutically useful proteins are produced in E. coli expression system, it is very are rare for the system to be used in the production of diagnostic antigen due to a major problem, i.e., false-positive reaction of e. coli host-derived proteins contaminating purified diagnostic antigen with human sera. The N (nucleocapsid) protein of Seoul virus causing haemorrhagic fever with renal syndrome (HFRS) was produced in E. coli BL21 (DE3), and used for the detection of N protein-specific antibodies in human sera. Using the N protein as a diagnostic antigen of HFRS, the false-positive reaction was cleared by merely mixing the test sera with the extract of E. coli host strain not harboring expression plasmid.