• YAKHAK HOEJI
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• v.44 no.3
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• pp.205-212
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• 2000

The effect of BRL 34915, a $K^{+}$ channe$Na^{+}$l opener, on renal function was investigated in anesthetized dog. BRL 34915, when given into the vein, elicited the decrease of urine volume accompanied with the reduction of renal plasma flow (RPF), osmolar clearance ($C_{osm}$) and amounts of sodium excreted into urine ($E_{na}$), whereas reabsorption rate of sodium in renal tubules ($R_{na}$), ratio of $K^{+}$ against $Na^{+}$ in urine ($K^{+}$ /$Na^{+}$) were elevated significantly with a partial fall of mean arterial pressure (MAP). BRL 34915 injected into a renal artery produced the diuretic action along with the increase in RPF $C_{osm}$, $E_{na}$ and amounts of potassium excreted in urine ($E_{k}$), and the decrease in $R_{na}$, reabsorption rate of potassium in renal tubules ($R_{k}$), free water clearance ($C_{H20}$) and $K^{+}/Na^{+}$ ratio in only ipsilateral kidney, however changes of the renal function were not observed in control kidney. BRL 34915 given into carotid artery exhibited the same aspect as changes of renal function induced by intravenous BRL 34915. These results suggest that BRL 34915 has dual effects, renally acting diuretic and centrally acting antidiuretic action.n.

• Journal of the Korean Ceramic Society
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• v.45 no.7
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• pp.395-400
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• 2008

This paper indicates the investigation about the development of ET (Environmental Technology) industrial geopolymeric materials from mixture silica mine waste, coal fly ash and alkali activator solution (sodium silicate) by the geopolymer technique at ambient temperature. The results showed that higher compressive strength of geopolymeric mortar increased with a reduce of L/S ratio and increased along with an increase of coal fly ash content. The compressive strengths of geopolymer mortar on low silica of C Silica Mine and K Silica Mine are 18.7 MPa, 20.4 MPa, respectively. Compressive strength of geopolymeric mortar depends on L/S ratio and coal fly ash content added.. Additionally, scanning electron microscope (SEM) techniques are used to characterize the microstructure of the geopolymeric mortars. SEM observation shows that it is possible to have amorphous aluminosilicate gel within mortar. XRD patterns indicate the fact that geopolymeric mortar is composed of amorphous aluminosilicate phase, calcite and quartz.

• Geotechnical Engineering
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• v.10 no.1
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• pp.27-46
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• 1994

It has been demonstrated in plane strain compression tests performed on dense Toyoura sand and Silver Leighton Buzzard sand, that the newly developed instrumentation for small strain measurements was capable of measuring the altering stiffness of sands for a wide range of shear strain from ($10^{-6}$to $10^{-2}$. It was found that for the range of shear strain($\gamma$) from $10^{-5}$ to those at peak, the Rowe's stressiilatancy relation seemed to be a good approximation for Toyoura sand and Silver Leighton Buzzard sand. However, the value of K and Poisson's ratio(at elastic range:${\nu}_{psc}^e$) varied with sand types. It was also found that the value of ${\nu}_{psc}^e$ and stress -dilatancy relation was irrespective of overconsolidation ratio(OCR).

• Phonetics and Speech Sciences
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• v.6 no.2
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• pp.141-151
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• 2014

This study reports anti-hierarchical initial-syllable lengthening of an utterance-internal phrase in Korean. That is, the phrase-initial syllable (e.g., /a/ of "apa-do" or /ma/ of "mapa-do") starting with a voiced phoneme (i.e., vowels or voiced consonants) manifests itself as significantly longer when it is preceded by another phrase without a pause than when it leads an utterance or follows a pause utterance-internally. The phenomenon was examined with regard to two other factors: (1) tempo and (2) tenseness of the consonant (/p, $p^{\prime}$, $p^h$/) following the target syllable /a/. First, the effect of tempo on initial lengthening was not significant. Apart from the statistical significance, however, a tendency was observed, i.e., the slower the tempo is, the greater the lengthening. By contrast, the faster the tempo is, the higher the ratio (%) of lengthening. Second, contrary to our expectations, initial-syllable lengthening was even greater before tense stops /$p^{\prime}$, $p^h$/ than before lax stop /p/ regardless of tempo, and it was remarkable when it comes to the ratio (%), which means that initial lengthening is free of the pre-consonantal vowel shortening effect. Final-syllable lengthening is a pre-boundary marker, while the initial-syllable lengthening is regarded as a post-boundary marker of a phrase.

• Preventive Nutrition and Food Science
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• v.20 no.3
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• pp.176-182
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• 2015

Abalone protein was hydrolyzed by enzymatic hydrolysis and the optimal enzyme/substrate (E/S) ratios were determined. Abalone protein hydrolysates (APH) produced by Protamex at E/S ratio of 1:100 showed angiotensin I converting enzyme inhibitory activity with $IC_{50}$ of 0.46 mg/mL, and APH obtained by Flavourzyme at E/S ratio of 1:100 possessed the oxygen radical absorbance capacity value of $457.6{\mu}M$ trolox equivalent/mg sample. Flavourzyme abalone protein hydrolysates (FAPH) also exhibited $H_2O_2$ scavenging activity with $IC_{50}$ of 0.48 mg/mL and $Fe^{2+}$+ chelating activity with $IC_{50}$ of 2.26 mg/mL as well as high reducing power. FAPH significantly (P<0.05) protected $H_2O_2$-induced hepatic cell damage in cultured hepatocytes, and the cell viability was restored to 90.27% in the presence of FAPH. FAPH exhibited 46.20% intracellular ROS scavenging activity and 57.89% lipid peroxidation inhibition activity in cultured hepatocytes. Overall, APH may be useful as an ingredient for functional foods.

• Journal of Environmental Health Sciences
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• v.31 no.2 s.83
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• pp.172-178
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• 2005

A laboratory experiment was performed to investigate simultaneous removal of phosphorus and nitrogen from raw sewage by intermittently aerated activated sludge process packed with aluminum and silver plate. Two continuous experimental process, i.e. an intermittently aerated activated sludge process, and an intermittently aerated activated sludge process with an aluminum and silver plate packed into the reactor were compared. The pitting corrosion of aluminum does not affect the performance of the biological treatment. The amounts of Al eluted from aluminum plate 17 mg to 60.6 mg in this experimental conditions, and Al/P mole ratio were from 3.31 to 11.25. The total nitrogen removal efficiency in Run E were $60.6\%$ at the HRT of 12 hours. The effluent $PO_4-P$ concentration as low as $1.0\;mg/\iota$ could have been obtained during the continuous experiment in Run E at HRT of 12 hours.

• Transactions of the Korean Society of Automotive Engineers
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• v.22 no.7
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• pp.84-89
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• 2014

Not only the emission regulation of on-road vehicle engine, but also emission regulation of off-road engine have been reinforced. It is the reason of wide application of emission reduction technology for off-road engines. In this study, optimization of engine parameters (Injector hole number, Injection timing and EGR rate) for reduction of NOx and smoke emissions were conducted by using the analysis of sensitivity and S/N ratio of Taguchi method(DOE). As results, this paper shows optimum value of the parameters for NOx and smoke emission reduction. From the result of reproducibility verification, it is final that the prediction value of NOx and smoke has the error of below 10%. Consequently, the method and results of this study will be used for quantitative reference to EGR control mapping in next study.

• The Journal of Society for e-Business Studies
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• v.9 no.2
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• pp.109-121
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• 2004

In this paper, we propose a system that generates a new customizing information for customer with classification and analysis in detail and provides customized information to individual customers automatically. A proposed system generate preference information and preference e-mail format as analysis and calculate that e-mail open rate and mouse event information. Using generated interesting information and preference e-mail format, individual customer's interest information according to e-mail standard and format that customer prefers through agent automatically recompose and push to customer. From experiment, the designed and implemented system showed high e-mail open ratio and user's satisfaction in performance assessment.

• Biomolecules & Therapeutics
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• v.14 no.4
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• pp.189-193
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• 2006

This study was designed to assess the distribution of cytochrome P450 2E1 (CYP2E1) polymorphism among Korean patients on warfarin therapy. CYP2E1 polymorphism was analyzed at 5' flanking region of CYP2E1 gene using restriction fragment length polymorphism method. Patient characteristics including the measured internal normalized ratio (INR) were also evaluated. Based on the warfarin dose and the bleeding cases, the patients were grouped as the regular dose control, the regular dose bleeding, the low dose control, and the low dose bleeding. Total 96 patients were evaluated for both Pst I and Rsa I loci of the CYP2E1 gene and the results showed that both loci were tightly linked. Thirty-three patients(34.4%) were heterozygotes and 4 patients(4.2%) were homozygote. There was no significant difference in patient characteristics in the dose and bleeding case groups. CYP2E1 polymorphism showed a little difference among the groups but was not statistically significant, however, lower INR value was observed in homozygote genotype groups. It was also revealed that genotype allele frequencies of CYP2E1 in Korean was close to other Asian groups but was significantly different from other Caucasian and African-American populations.

• The Journal of Korean Academy of Prosthodontics
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• v.26 no.1
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• pp.31-49
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• 1988

This study was performed to investigate the sound distortion following the alternation of the palatal plate thickness, for this study, 3 subjects who were born in Seoul and spoke Seoul dialect were recruited from K university male student population. First, their sounds of /아(a)/, 어(e)/, 오(o)/, 우(u)/, 으($\.{+}$), 이(i)/,에(e)/ without inserting plate were recorded , and then the sounds with palatal plates of different thickness were recorded, respectively. The palatal plates was constructed to cover the alveolar & palatal surfaces of the maxilla with an approximate thickness of 1.0mm, 2.5mm, and thickness of 2.5mm over the alveolar ridge & 1.0mm elsewhere and, named B, C, D-type, in succession. Series of analysis were administered through Computer (16 bit IBM PC/AT) at analyze the sound distortions. These experiments were analyzed by the LPC, Log Area Ratio. The findings led to the following conclusions: 1. Sound distortions were relatively minute in each condition and informations, however, /이(i)/ was the most distorted vowel in all conditions. 2. By and large, sound distortion was large in C, D-types. However, there was no correlation of the distortion rate on the 3 informants, and all tested vowels. 3. It was similar to LPC, Log Area Ratio distortion rates. 4. It was found that the sound distortion wit]1 plate inserted was verified to the numeric value with LPC and Log Area Ratio method.