• Journal of the Korean Electrochemical Society
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• v.19 no.4
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• pp.134-140
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• 2016

An aptamer-based biosensor using a new redox indicator has been examined for the electrochemical detection of thrombin. The aptamer modified primary aliphatic amine was covalently immobilized onto poly-(5,2':5',2"-terthiophene-3'-carboxylic acid) (polyTTCA) layer. Tetrabromophenolphthalein ethyl ester (KTBPE) was interacted to aptamer and used as an electrochemical indicator. Prior to the detection, the oxidation reaction of KTBPE onto aptamer modified layer was also investigated using differential pulse voltammetry. The characterization of the final sensor (KTBPE/aptamer -polyTTCA) was performed by voltammetry, QCM, and ESCA. After binding of thrombin onto KTBPE/aptamer based sensor, the peak signal of KTBPE was gradually decreased. The sensor exhibited a dynamic range between 10.0 and 100.0 nM with the detection limit of $1.0{\pm}0.2nM$.

• Journal of the Korean Society of Hazard Mitigation
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• v.9 no.4
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• pp.21-28
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• 2009

Most of domestic shipyards are located at coastal regions which are affected by typhoons nearly every year. For effectiveness of shipbuilding, shipyards contain many facilities which are light-weighted and affected dominantly by wind. In the present paper, we analyze various wind fields over a shipyard including surrounding topology and structures to evaluate the structural safety of the facilities posed in the strong wind. Extreme wind speed for a study region was estimated by typhoon Monte Carlo simulation and then used for inlet wind speed for CFD analysis for wind load on the facilities. Considering geometrical wind effects, we assess the surface pressure of the elements as the pressure factor, the ratio of surface pressure to dynamic pressure. The results show that the simulated wind speed is greater than the design wind speed for the some facilities because of the shipyard's geometry. It also shows that surrounding topography in coastal area is needed to be considered and adjustment for design wind speed at wind load standard application is necessary for mooring ship and industry facilities.

• Journal of Korean Society of Steel Construction
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• v.25 no.6
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• pp.649-658
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• 2013

Recently, an urgent issue of the global environment in the 21st century is the well-established paradigm of a sustainable and circulatory system. In the field of construction, it is important to approach sustainablity issues from a structural engineering point of view. The reusable steel structural system, which can adapt to changes in socio-economic conditions and varied demands, realized that the consumption of natural resources was minimized, the environmental load was reduced as much as possible. In order to reuse and recombinant the structural members, removable PC slab connection was introduced. This paper investigates the structural performance and serviceability by the dynamic characteristics of the steel beam to concrete slab connection.

• International Journal of Vascular Biomedical Engineering
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• v.2 no.1
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• pp.17-24
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• 2004

Tumor angiogenesis was simulated using a two-dimensional computational model. The equation that governed angiogenesis comprised a tumor angiogenesis factor (TAF) conservation equation in time and space, which was solved numerically using the Galerkin finite element method. The time derivative in the equation was approximated by a forward Euler scheme. A stochastic process model was used to simulate vessel formation and vessel elongation towards a paracrine site, i.e., tumor-secreted basic fibroblast growth factor (bFGF). In this study, we assumed a two-dimensional model that represented a thin (1.0 mm) slice of the tumor. The growth of the tumor over time was modeled according to the dynamic value of bFGF secreted within the tumor. The data used for the model were based on a previously reported model of a brain tumor in which four distinct stages (namely multicellular spherical, first detectable lesion, diagnosis, and death of the virtual patient) were modeled. In our study, computation was not continued beyond the 'diagnosis' time point to avoid the computational complexity of analyzing numerous vascular branches. The numerical solutions revealed that no bFGF remained within the region in which vessels developed, owing to the uptake of bFGF by endothelial cells. Consequently, a sharp, declining gradient of bFGF existed near the surface of the tumor. The vascular architecture developed numerous branches close to the tumor surface (the brush-border effect). Asymmetrical tumor growth was associated with a greater degree of branching at the tumor surface.

• Environmental and Resource Economics Review
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• v.18 no.1
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• pp.75-103
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• 2009

The hypothesis suggested by Porter and van der Linde claims that innovating firms operate in a dynamic competitive situation which allows global diffusion of environmental-friendly technologies. Therefore, countries that are subjects to more stringent environmental regulations may become net exporters of environmental technologies. In the context of Porter hypothesis, this study investigates the impact of importing countries' environmental regulation on Korea and Japan's export flows of technologies for renewable energies and energy efficiency by estimating the gravity equation. The estimation result shows that : (1) our results are consistent with the Porter hypothesis where environmental regulation represents a significant source of comparative advantages, (2) Korea's export flows of technologies for renewable energies and energy efficiency with respect to the importing countries' environmental regulation are more sensitive than Japan's, and (3) the adverse relationship between export flows and importers' environmental stringency in developing countries does not hold in the renewable energies and energy efficiency related sector.

• Journal of the Korean Society of Industry Convergence
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• v.20 no.1
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• pp.34-48
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• 2017

This study proposes a new approach to control a trajectory control of vertical type articulated robot arm with six revolution joints by computed torque method for manufacturing process automation. The proposed control scheme takes advantage of the properties of the fuzzy controllers. The proposed method is suitable to control of the trajectory and path control in cartesian space for vertical type articulated robot manipulator for forging manufacturing process automation. The results is illustrated that the proposed fuzzy computed torque controller is more stable and robust than the conventional computed torque controller. This study is included with an analytical methodology of inverse kinematic computation for 6 DOF manipulators. And an intelligent PID based on feed forward fuzzy control structure is applied to control the working path control with disturbances caused by uncertainty parameters of the manipulator dynamic model. Lastly, the validity of proposed is verified by simulations and experiments.

• Applied Chemistry for Engineering
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• v.5 no.6
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• pp.981-989
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• 1994

For the development of new material used bentonite in ceramic/organic material composite, ABS(acrylonitrile-butadiene-styrene) material was used as a matrix polymer and a series of bentonite was blended together. This bentonite, filler like talc or mica for plastic material, was used since natural bentonite(Ca type) is easily obtainable in Korea, Na-bentonite changed from natural bentonite by $Na_2CO_3$ based on the specified compositions, changes in the static and dynamic mechanical properties. It was discovered that the increased content of natural and Na- bentonite results in higher modulus with reduced impact strength. And Rockwell hardness was constant. And Na- bentonite filled polymer showed improvement in impact strength and lower in modulus as the natural bentonite filled polymer. The storage modulus(E') of Na- bentonite filled ABS resin was higher than that of Ca- bentonite filled ABS resin, while higher temperature, storage modulus(E') decreased. At higher frequency, tan ${\delta}$ peak was shifted at high temperature.

• Journal of the Korean Vacuum Society
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• v.21 no.2
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• pp.86-92
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• 2012

We have studied the effect of speed of deposited atom on morphology evolution during Glancing Angle Deposition (GLAD). Using Kinetic Monte Carlo simulation that incorporate molecular dynamics simulations, we have shown that the rough surface morphology became smoother as the speed of deposited atom is increased. The growth exponent ${\beta}$ change from 0.97 to 0.67 as the speed increase from ${\upsilon}_0$ to $10{\upsilon}_0$ in the case of GLAD. We also examined the effect of speed of deposited atom for the case of chemical vapor deposition (CVD) simulation. Compared to GLAD, the variation in scaling exponent ${\beta}$ is small but the speed of deposited atom also have considerable effect on growth morpholgy in the case of CVD.

• Journal of Korea Foresty Energy
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• v.25 no.2
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• pp.49-54
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• 2006

This study was carried out to provide basic data for using domestic structural softwood lumber efficiently and ensuring structural safety of timber structures. The ratios (k-factor) between static and dynamic MOE measured by ultrasonic device for $2{\times}6$ domestic softwood structural lumber are 1.0602 for Korean red pine, 1.0013 for Korean white pine and 1.2320 for Japanese larch. In machine grade using nondestructive method, 76% of Korean red pine was classified into higher than E9 grade, 85% of Korean white pine was sorted into higher than E7 grade and 68% of Japanese larch was classified into higher than E11 grade. Correlation between MOE and MOR by static bending with k-factor from nondestructive method provide a possibility to predict bending strength and allowable stress of domestic softwood structural lumber.

• Journal of Korean Society of Steel Construction
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• v.23 no.3
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• pp.317-326
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• 2011

Today there is a growing range of applications for Concrete-Filled Steel Tube (CFT) member because of its superior performance. Ductility estimation test of concrete-filled seismic resistant steel tubular columns, subjected to axial and cyclic lateral load, was carried out in this study. Seismic resistant steel tubes are manufactured using SN400B plates by a two-seam welding at center of the column width for cold press-formed shape plates of two pieces. A total of eight specimens were manufactured and tested with the parameters of width-thickness ratio of steel tubular column, axial load ratio, and loading conditions to act axial and cyclic lateral load two dynamic actuators were used. From test results, flexural strength, deformation capacity, energy dissipation capacity, and ductility behavior of columns were analyzed.