• 한국자기공명학회논문지
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• 제25권4호
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• pp.58-63
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• 2021

Apolipoprotein B-100 (apo B-100), the main protein component that makes up LDL (Low density lipoprotein), consists of 4,536 amino acids and serves to combine with the LDL receptor. The oxidized LDL peptides by malondialdehyde (MDA) or acetylation in vivo act as immunoglobulin (Ig) antigens and peptide groups were classified into 7 peptide groups with subsequent 20 amino acids (P1-P302). The biomimetic peptide P143 (IALDD AKINF NEKLS QLQTY) out of C-group peptides carrying the highest value of IgG antigens were selected for structural studies that may provide antigen specificity. Experimental results show that P143 has β-sheet in Ile[1]-Asn[9] and α-helice in Gln[16]-Tyr[20] structure. Homonuclear 2D-NMR (COSY, TOCSY, NOESY) experiments were carried out for NMR signal assignments and structure determination for P143. On the basis of these completely assigned NMR spectra and proton distance information, distance geometry (DG) and molecular dynamic (MD) were carried out to determine the structures of P143. The proposed structure was selected by comparisons between experimental NOE spectra and back-calculated 2D NOE results from determined structure showing acceptable agreement. The total Root-Mean-Square-Deviation (RMSD) value of P143 obtained upon superposition of all atoms were in the set range. The solution state P143 has a mixed structure of pseudo α-helix and β-turn(Phe[10] to Glu[12]). These results are well consistent with calculated structure from experimental data of NOE spectra. Structural studies based on NMR may contribute to the prevent oxidation studies of atherosclerosis and observed conformational characteristics of apo B-100 in LDL using monoclonal antibodies.

• Journal of Welding and Joining
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• 제30권1호
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• pp.59-63
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• 2012

The spacer grid is one of the main structural components in a fuel assembly. It supports fuel rods, guides cooling water and maintains geometry from external impact load and cyclic stress by the vibration of nuclear fuel rod, it is necessary to have sufficient strength against dynamic external load and fatigue strength. In this study, the mechanical properties and fatigue characteristics of laser beam welded zircaloy thin sheet are examined. The material used in this study is a zirconium alloy with 0.66 mm of thickness. The fatigue strength under cyclic load was evaluated at stress ratio R=0.1. S-N curves are presented with statistical testing method recommend by JSME- S002 and compared with S-N curves at R.T. and $315^{\circ}C$. As a result of the experimental approach, the design guide of fatigue strength is proposed and the results obtained from this study are expected to be useful data for spacer gird design.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1989년도 봄 학술발표회 논문집
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• pp.38-43
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• 1989

하중 재하속도의 영향을 고려한 철근 콘크리트 부재의 거동을 예측하기 위한 해석모델이 layer modeling 기법에 의하여 개발되었다. 철근 콘크리트 부재의 압축 및 휨거동 해석 과정에서 하중에 따른 변형율 속도를 변수로 사용한 개발된 모델을 이용하여 얻은 해석결과는 여러가지 다른 하중재하 속도하에서 실험된 실험결과와 비교되었으며, 그의 비교결과는 만족스러웠다. 본 연구에서는 개발된 모델을 사용하여 철관 콘크리트 보 및 기둥에서 다양하게 사용될 수 있는 기하학적 형태 및 사용재료 등의 변수변환이 하중재하 속도에 따른 부재의 강도 및 강성에의 민감성을 조사하였다. 본 논문에서는 또한 하중재하 속도의 영향을 고려할 수 있는 철근 콘크리트 단면의 휨 및 압축강도를 계산할 수 있는 두개의 설계 공식도 제안하였다.

• East Asian mathematical journal
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• 제30권2호
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• pp.149-172
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• 2014

The problems of optimization addressed in the high school curriculum are usually posed in real-life contexts. However, because of the instructional purposes, problems are artificially constructed to suit computation, rather than to reflect real-life problems. Those problems have thus limited use for teaching 'practicalities', which is one of the goals of mathematics education. This study, by utilizing 'GeoGebra', suggests the optimization problem solving related to the quadratic curve, using the contour-line method which contemplates the quadratic curve changes successively. By considering more realistic situations to supplement the limit which deals only with numerical and algebraic approach, this attempt will help students to be aware of the usefulness of mathematics, and to develop interests in mathematics, as well as foster students' integrated thinking abilities across units. And this allows students to experience a variety of math.

• International Journal of Naval Architecture and Ocean Engineering
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• 제10권3호
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• pp.348-359
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• 2018

A series of indoor simulation tests on a large-sized shaking table was performed, which was used to simulate the earthquake ground motion for the pipe-soil interaction system to be tested. The purpose of this study is to examine the dynamic characteristic and seismic response of a length of PVC pipeline lay on a clay seabed under seismic load. The pipeline was fully instrumented to provide strain and acceleration responses in both transverse and in-line. Dynamical modal tests show that corresponding mode shapes vertically and horizontally are basically the same. But the absolute values of the natural frequencies vertically are all higher than those corresponding values in transverse. It turned out that the geometry configuration of riser affects its stiffness. Seismic response of pipeline depends significantly on the waveform, and Peak Ground Acceleration (PGA). As the seismic loading progressed, the strain response was severe around both TDZ and catenary zone. Additionally, strain responses in top and bottom positions were more severe than the result in left or right side of the pipeline in the same section.

• Earthquakes and Structures
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• 제12권3호
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• pp.359-374
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• 2017

The seismic events in Northern Italy, May 2012, have revealed the seismic vulnerability of typical Italian precast industrial buildings. The aim of this paper is to present a seismic fragility model for Italian RC precast buildings, to be used in earthquake loss estimation and seismic risk assessment by comparing two building typologies and three different codes: D.M. 3-03-1975, D.M. 16-01-1996 and current Italian building code that has been released in 2008. Based on geometric characteristics and design procedure applied, ten different building classes were identified. A Monte Carlo simulation was performed for each building class in order to generate the building stock used for the development of fragility curves trough analytical method. The probabilistic distributions of geometry were mainly obtained from data collected from 650 field surveys, while the material properties were deduced from the code in place at the time of construction or from expert opinion. The structures were modelled in 2D frameworks; since the past seismic events have identified the beam-column connection as the weakest element of precast buildings, two different modelling solutions were adopted to develop fragility curves: a simple model with post processing required to detect connection collapse and an innovative modelling solution able to reproduce the real behaviour of the connection during the analysis. Fragility curves were derived using both nonlinear static and dynamic analysis.

• 대한전자공학회논문지SD
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• 제38권5호
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• pp.375-381
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• 2001

디바이스의 크기가 0.25㎛이하로 축소됨에 따라 DRAM(Dynamic Random Access Memory) 제조업체들은 칩 크기를 줄이고 지역적인 배선으로 사용하기 위해서 기존의 텅스텐-폴리사이드 비트-선에서 텅스텐 비트-선으로 대체하고 있다. 본 논문에서는 다양한 RTP 온도와 추가 이온주입을 사용하여 낮은 저항을 갖는 텅스텐 비트-선 제조 공정에 대해 다루었다. 그 결과 텅스텐 비트선 저항에 중요한 메계변수는 RTP Anneal 온도와 BF₂ 이온 주입 도펀트임을 알 수 있었다. 이러한 텅스텐 비트-선 공정은 고밀도 칩 구현에 중요한 기술이 된다.

• 한국수소및신에너지학회논문집
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• 제31권3호
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• pp.314-321
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• 2020

In this work, a preliminary design of an inlet guide vane and runner for developing a 2.5 kW hydraulic turbine was conducted by using computational fluid dynamic analysis. Three-dimensional Reynolds-averaged Navier-Stokes equations with shear stress transport turbulence model were used to analyze the fluid flow in the hydraulic turbine. The hexahedral grid system was used to construct computational domain, and the grid dependency test was performed to obtain the optimal grid system. Velocity triangle diagram considering the flow angles of the inlet guide vane and runner was analyzed to obtain a basic geometry of the inlet guide vane and runner. Through modification of the preliminary design, the hydraulic performances of the turbine have improved under overall drop conditions. Especially, the efficiency and power of the turbine increased by 0.95% and 1.45%, respectively, compared to those of the reference model.

• 대한기계학회논문집A
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• 제21권3호
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• pp.369-377
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• 1997

The torque converter, a major part of automatic transmissions, has many difficulties in analysis due to the factors such as power transmission through fluid flow, complex internal geometry, and various operating conditions. Because of such difficulties, the dynamic analysis and design of a torque converter are generally carried out by using equivalent performance model which is based on the concept of mean flow path. Since the design procedures of a torque converter are essential technology of automotive industry, the details of the procedures are rarely published. In this study, the basic design procedures of a torque converter are systemized and coded based on the equivalent performance model. The mathematical methods to deal with mean flow path determination and the core-shape are developed. And by using this model, the method of determination of performance parameters satisfying the requested performance is proposed. Finally, to embody the three-dimensional shape, the intermediate blade angles which maximize the tractive performance are determined and laid out.

• 한국자동차공학회논문집
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• 제15권6호
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• pp.151-158
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• 2007

The static and dynamic behaviour of VGT and EGR systems has a significant impact on overall engine performance, fuel economy and exhaust emissions. This is because they define the state and composition of the air charge entering the engine. This work focused on the effect of the aperture ratio of VGT and EGR on the emission and flow characteristics under partial loads conditions. The investigation carried out using 2 liter PCCI 4 cylinder diesel engine with VGT and EGR. The result of this study shows that smoke increases with increasing EGR rate and NOx decreases with increasing EGR rate. It was also found that the residual gas contents greatly impact on soot emission under partial load condition. Finally, it can be concluded that VGT and EGR aperture ratio can greatly impact not only on soot and NOx but also air charging.