• 한국공작기계학회논문집
• /
• 제13권1호
• /
• pp.22-27
• /
• 2004

A new method that estimates the sensing ability of HH smart sensor is proposed. The new signal processing method have been developed that can distinguish among different materials relatively. The HH smart sensor was developed far recognition of materials. The HH smart sensor was made for experiment. Then, it was estimated the ability to recognize objects according to acceleration value. The sensing ability of HH smart sensor has been estimated with the $R_{SAI}$ method. Experiments and analysis were executed to estimate the ability to recognize objects according to acceleration value changing. Dynamic characteristics of HH smart sensor were evaluated relatively through a new $R_{SAI}$ method that uses the power spectrum density. Applications of this method are for finding abnormal conditions of objects (auto-manufacturing), feeling of objects (medical product), robotics, safety diagnosis of structure, etc.

• 대한정형외과 초음파학회지
• /
• 제6권1호
• /
• pp.28-37
• /
• 2013

초음파는 슬관절의 초기 검사에 이용할 수 있고 다양한 슬관절 병변을 평가하는 유용한 진단 장비이다. 슬관절의 초음파 검사는 비침습적이며 쉽게 이용할 수 있고 비교적 저렴하여 환자의 검사에 대한 저항감이 적고 동적 검사가 가능한 기술적인 장점이 있다. 검사의 한계는 신뢰도가 주로 검사자의 숙련 정도에 좌우되고 심부 구조는 볼 수 없다는 점이다. 유럽 근골격계 방사선학회에서 제시한 초음파 검사의 기본 술기 지침과 함께 여러 슬관절 병변에 대한 소견들을 소개하고자 한다.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 2000년도 하계학술대회 논문집 B
• /
• pp.726-728
• /
• 2000

In this paper, after considering the standard data that are obtained by the study of the dynamic and mechanical characteristics (such as the torque characteristics and the force distribution analysis of the wobble motor), we design the prototype of the magnetostatic wobble motor. It can be applied to the high-precision medical instruments such as the ultrasonic catheter for the diagnosis and treatment of vascular disease.

• Smart Structures and Systems
• /
• 제13권5호
• /
• pp.775-796
• /
• 2014

This study presents a vibration-based health monitoring strategy for short span bridges utilizing an inspection vehicle. How to screen the health condition of short span bridges in terms of a drive-by bridge inspection is described. Feasibility of the drive-by bridge inspection is investigated through a scaled laboratory moving vehicle experiment. The feasibility of using an instrumented vehicle to detect the natural frequency and changes in structural damping of a model bridge was observed. Observations also demonstrated the possibility of diagnosis of bridges by comparing patterns of identified bridge dynamic parameters through periodical monitoring. It was confirmed that the moving vehicle method identifies the damage location and severity well.

• 한국컴퓨터정보학회:학술대회논문집
• /
• 한국컴퓨터정보학회 2018년도 제57차 동계학술대회논문집 26권1호
• /
• pp.85-86
• /
• 2018

본 논문에서는 사이버공격의 주요 대상인 웹 애플리케이션의 보안을 위하여 취약점진단 및 제거, 이행점검의 웹 통합보안관리 플랫폼을 제안한다. 이 플랫폼은 동적진단엔진, 취약점제거보안모듈, UI를 제공하는 통합관리시스템, 진단 결과를 저장하는 결과 및 통계 DB, 와 진단을 위한 관련 정보를 저장하는 진단 및 보안정보 DB로 구성되며, 동적진단결과에 대한 상관관계분석 기능과 취약점 개선 활동 시 스마트 보안모듈을 통해 빠르고 손쉬운 취약점 제거수정, 완화할 수 있는 통합플랫폼 연구를 통하여 웹 애플리케이션보안을 효율적으로 할 수 있다.

• Journal of Information Processing Systems
• /
• 제4권3호
• /
• pp.103-112
• /
• 2008

This paper proposes a policy adjuster-driven Grid workflow management system for collaborative healthcare platform, which supports collaborative heart disease diagnosis applications. To select policies according to service level agreement of users and dynamic resource status, we devised a policy adjuster to handle workflow management polices and resource management policies using policy decision scheme. We implemented this new architecture with workflow management functions based on policy quorum based resource management system for providing poincare geometrycharacterized ECG analysis and virtual heart simulation service. To evaluate our proposed system, we executed a heart disease identification application in our system and compared the performance to that of the general workflow system and PQRM system under different types of SLA.

• 한국진공학회:학술대회논문집
• /
• 한국진공학회 2013년도 제45회 하계 정기학술대회 초록집
• /
• pp.87-87
• /
• 2013

The interface between nanomaterials and biosystems is emerging as one of the broadest and most dynamic areas of science and technology, bringing together biology, chemistry, physics and many areas of engineering, biomedicine. The combination of these diverse areas of research promised to yield revolutionary advances in healthcare, medicine, and life science. For example, the creation of new and powerful nanosensors that enable direct, sensitive, and rapid analysis of biological and chemical species can advance the diagnosis and treatment of disease, discovery and screening of new drug molecules. Nanowire based sensors are emerging as a powerful and general platform for ultrasensitive and multiplex detection of biological and chemical species. Here, we present the studies about noble metal nanowire sensors that can be used for sensitive detection of a wide-range of biological and chemical species including nucleic acids, proteins, and toxic metal ions. Moreover, the optical and electrochemical applications of noble metal nanowires are introduced. Noble metal nanowires are successfully used as plasmonic antennas and nanoelectrodes, thereby provide a pathway for a single molecule sensor, in vivo neural recording, and molecular injection and detection in a single living cell.

• 대한의용생체공학회:의공학회지
• /
• 제20권5호
• /
• pp.545-557
• /
• 1999

본 논문에서는 호흡 연동 장치와 EBT로부터 획득한 폐실질 영상에 대하여 동적 윤곽선 모델 방법과 영역 성장법을 이용하여 폐실질 영역을 검출하였다. 그런 다음 , 검출된 폐실질 영역내에서의 각종 정량적 요소들을 도출하여 농도 분포 곡선에대한 분석을 하였다. 동적 윤곽선 모델방법에서 페실질 영역의 낮은 휘도 준위와 폐의 윤곽선 벡터 방향을 고려한 에너지 함수를 제안하였다. 그리고 폐실질 영역 성장법에서는 폐실질 영역내의 분포한 공기 성분에 대한 화소를 확장시켜 효과적으로 폐실질 영역을 검출하였다. 추출된 폐실질 영역내의 빈도 분포 곡선을 분석하여 정상군과 비교한 결과 만성 폐쇄성 폐질환자에서는 정상인에 비하여 평균 농도,최대 빈도 농도, 최대 상승 기울기 농도가 낮았으며, 농도 분포곡선은 더 낮은 쪽으로 이동하였음을 알 수 있었다. 또한, 특발성 폐섬유증 환자에서는 평균 농도, 최대 빈도 농도, 최대 상승 기울기 농도가 모두 증가되었고 농도 분포 곡선은 더 높은쪽으로 이동하였다. 폐실질 영역을 추출하여 히스토그램 분포에 대한 정량적 분석을 함으로써 정상인으로부터 만성 폐쇄성 질환자의 폐섬유증 환자를 구분할 수 있었다.

• Smart Structures and Systems
• /
• 제22권6호
• /
• pp.711-725
• /
• 2018

Most of the practical engineering structures exhibit nonlinearity due to nonlinear dynamic characteristics of structural joints, nonlinear boundary conditions and nonlinear material properties. Hence, it is highly desirable to detect and characterize the nonlinearity present in the system in order to assess the true behaviour of the structural system. Further, these identified nonlinear features can be effectively used for damage diagnosis during structural health monitoring. In this paper, we focus on the detection of the nonlinearity present in the system by confining our discussion to only a few selective time-frequency analysis and multivariate analysis based techniques. Both damage induced nonlinearity and inherent structural nonlinearity in healthy systems are considered. The strengths and weakness of various techniques for nonlinear detection are investigated through numerically simulated two different classes of nonlinear problems. These numerical results are complemented with the experimental data to demonstrate its suitability to the practical problems.

• BMB Reports
• /
• 제52권2호
• /
• pp.113-118
• /
• 2019

The small ubiquitin-related modification molecule (SUMO), one of the post-translational modification molecules, is involved in a variety of cellular functions where it regulates protein activity and stability, transcription, and cell cycling. Modulation of protein SUMOylation or deSUMOylation modification has been associated with regulation of carcinogenesis in breast cancer. In the dynamic processes of SUMOylation and deSUMOylation in a variety of cancers, SUMO proteases (SENPs), reverse SUMOylation by isopeptidase activity and SENPs are mostly elevated, and are related to poor patient prognosis. Although underlying mechanisms have been suggested for how SENPs participate in breast cancer tumorigenesis, such as through regulation of target protein transactivation, cancer cell survival, cell cycle, or other post-translational modification-related machinery recruitment, the effect of SENP isoform-specific inhibitors on the progression of breast cancer have not been well evaluated. This review will introduce the functions of SENP1 and SENP2 and the underlying signaling pathways in breast cancer for use in discovery of new biomarkers for diagnosis or therapeutic targets for treatment.