• Proceedings of the KIEE Conference
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• 2000.07b
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• pp.726-728
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• 2000

In this paper, after considering the standard data that are obtained by the study of the dynamic and mechanical characteristics (such as the torque characteristics and the force distribution analysis of the wobble motor), we design the prototype of the magnetostatic wobble motor. It can be applied to the high-precision medical instruments such as the ultrasonic catheter for the diagnosis and treatment of vascular disease.

• Smart Structures and Systems
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• v.13 no.5
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• pp.775-796
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• 2014

This study presents a vibration-based health monitoring strategy for short span bridges utilizing an inspection vehicle. How to screen the health condition of short span bridges in terms of a drive-by bridge inspection is described. Feasibility of the drive-by bridge inspection is investigated through a scaled laboratory moving vehicle experiment. The feasibility of using an instrumented vehicle to detect the natural frequency and changes in structural damping of a model bridge was observed. Observations also demonstrated the possibility of diagnosis of bridges by comparing patterns of identified bridge dynamic parameters through periodical monitoring. It was confirmed that the moving vehicle method identifies the damage location and severity well.

• Proceedings of the Korean Society of Computer Information Conference
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• 2018.01a
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• pp.85-86
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• 2018

본 논문에서는 사이버공격의 주요 대상인 웹 애플리케이션의 보안을 위하여 취약점진단 및 제거, 이행점검의 웹 통합보안관리 플랫폼을 제안한다. 이 플랫폼은 동적진단엔진, 취약점제거보안모듈, UI를 제공하는 통합관리시스템, 진단 결과를 저장하는 결과 및 통계 DB, 와 진단을 위한 관련 정보를 저장하는 진단 및 보안정보 DB로 구성되며, 동적진단결과에 대한 상관관계분석 기능과 취약점 개선 활동 시 스마트 보안모듈을 통해 빠르고 손쉬운 취약점 제거수정, 완화할 수 있는 통합플랫폼 연구를 통하여 웹 애플리케이션보안을 효율적으로 할 수 있다.

• Journal of Information Processing Systems
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• v.4 no.3
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• pp.103-112
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• 2008

This paper proposes a policy adjuster-driven Grid workflow management system for collaborative healthcare platform, which supports collaborative heart disease diagnosis applications. To select policies according to service level agreement of users and dynamic resource status, we devised a policy adjuster to handle workflow management polices and resource management policies using policy decision scheme. We implemented this new architecture with workflow management functions based on policy quorum based resource management system for providing poincare geometrycharacterized ECG analysis and virtual heart simulation service. To evaluate our proposed system, we executed a heart disease identification application in our system and compared the performance to that of the general workflow system and PQRM system under different types of SLA.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.08a
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• pp.87-87
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• 2013

The interface between nanomaterials and biosystems is emerging as one of the broadest and most dynamic areas of science and technology, bringing together biology, chemistry, physics and many areas of engineering, biomedicine. The combination of these diverse areas of research promised to yield revolutionary advances in healthcare, medicine, and life science. For example, the creation of new and powerful nanosensors that enable direct, sensitive, and rapid analysis of biological and chemical species can advance the diagnosis and treatment of disease, discovery and screening of new drug molecules. Nanowire based sensors are emerging as a powerful and general platform for ultrasensitive and multiplex detection of biological and chemical species. Here, we present the studies about noble metal nanowire sensors that can be used for sensitive detection of a wide-range of biological and chemical species including nucleic acids, proteins, and toxic metal ions. Moreover, the optical and electrochemical applications of noble metal nanowires are introduced. Noble metal nanowires are successfully used as plasmonic antennas and nanoelectrodes, thereby provide a pathway for a single molecule sensor, in vivo neural recording, and molecular injection and detection in a single living cell.

• Journal of Biomedical Engineering Research
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• v.20 no.5
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• pp.545-557
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• 1999

본 논문에서는 호흡 연동 장치와 EBT로부터 획득한 폐실질 영상에 대하여 동적 윤곽선 모델 방법과 영역 성장법을 이용하여 폐실질 영역을 검출하였다. 그런 다음 , 검출된 폐실질 영역내에서의 각종 정량적 요소들을 도출하여 농도 분포 곡선에대한 분석을 하였다. 동적 윤곽선 모델방법에서 페실질 영역의 낮은 휘도 준위와 폐의 윤곽선 벡터 방향을 고려한 에너지 함수를 제안하였다. 그리고 폐실질 영역 성장법에서는 폐실질 영역내의 분포한 공기 성분에 대한 화소를 확장시켜 효과적으로 폐실질 영역을 검출하였다. 추출된 폐실질 영역내의 빈도 분포 곡선을 분석하여 정상군과 비교한 결과 만성 폐쇄성 폐질환자에서는 정상인에 비하여 평균 농도,최대 빈도 농도, 최대 상승 기울기 농도가 낮았으며, 농도 분포곡선은 더 낮은 쪽으로 이동하였음을 알 수 있었다. 또한, 특발성 폐섬유증 환자에서는 평균 농도, 최대 빈도 농도, 최대 상승 기울기 농도가 모두 증가되었고 농도 분포 곡선은 더 높은쪽으로 이동하였다. 폐실질 영역을 추출하여 히스토그램 분포에 대한 정량적 분석을 함으로써 정상인으로부터 만성 폐쇄성 질환자의 폐섬유증 환자를 구분할 수 있었다.

• Smart Structures and Systems
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• v.22 no.6
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• pp.711-725
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• 2018

Most of the practical engineering structures exhibit nonlinearity due to nonlinear dynamic characteristics of structural joints, nonlinear boundary conditions and nonlinear material properties. Hence, it is highly desirable to detect and characterize the nonlinearity present in the system in order to assess the true behaviour of the structural system. Further, these identified nonlinear features can be effectively used for damage diagnosis during structural health monitoring. In this paper, we focus on the detection of the nonlinearity present in the system by confining our discussion to only a few selective time-frequency analysis and multivariate analysis based techniques. Both damage induced nonlinearity and inherent structural nonlinearity in healthy systems are considered. The strengths and weakness of various techniques for nonlinear detection are investigated through numerically simulated two different classes of nonlinear problems. These numerical results are complemented with the experimental data to demonstrate its suitability to the practical problems.

• BMB Reports
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• v.52 no.2
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• pp.113-118
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• 2019

The small ubiquitin-related modification molecule (SUMO), one of the post-translational modification molecules, is involved in a variety of cellular functions where it regulates protein activity and stability, transcription, and cell cycling. Modulation of protein SUMOylation or deSUMOylation modification has been associated with regulation of carcinogenesis in breast cancer. In the dynamic processes of SUMOylation and deSUMOylation in a variety of cancers, SUMO proteases (SENPs), reverse SUMOylation by isopeptidase activity and SENPs are mostly elevated, and are related to poor patient prognosis. Although underlying mechanisms have been suggested for how SENPs participate in breast cancer tumorigenesis, such as through regulation of target protein transactivation, cancer cell survival, cell cycle, or other post-translational modification-related machinery recruitment, the effect of SENP isoform-specific inhibitors on the progression of breast cancer have not been well evaluated. This review will introduce the functions of SENP1 and SENP2 and the underlying signaling pathways in breast cancer for use in discovery of new biomarkers for diagnosis or therapeutic targets for treatment.

• Clinical Pain
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• v.19 no.2
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• pp.64-69
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• 2020

Ultrasound (US) imaging is an efficient, easy to use, rapid, dynamic, noninvasive, with rare side-effects and inexpensive tool allowing for facilitated diagnosis and management of the painful shoulder. It also has advantages over other imaging modalities in the evaluation of the postoperative shoulder for rotator cuff integrity and correct anchor and suture placement, as well as rotator cuff analysis following repair surgery. Early postoperative tendons frequently had a hypo- echoic echo texture and the absence of a fibrillar pattern, which might be misinterpreted as recurrent tears. however, these features often normalized into tendons with an increased echo texture and the reappearance of a fibrillar pattern at 6 months. Based on these sequential findings, the US findings within 3 months after surgery should be interpreted with caution to accurately understand and monitor the repaired tendon status.

• Journal of information and communication convergence engineering
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• v.20 no.3
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• pp.153-159
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• 2022

Plain radiographic analysis is the initial imaging modality for suspected small bowel obstruction. Among the many features that affect the diagnosis of small bowel obstruction (SBO), the presence of gas-filled or fluid-filled small bowel loops is the most salient feature that can be automatized by computer vision algorithms. In this study, we compare three frequently applied pixel-clustering algorithms for extracting gas-filled areas without human intervention. In a comparison involving 40 suspected SBO cases, the Possibilistic C-Means and Fuzzy C-Means algorithms exhibited initialization-sensitivity problems and difficulties coping with low intensity contrast, achieving low 72.5% and 85% success rates in extraction. The Adaptive Resonance Theory 2 algorithm is the most suitable algorithm for gas-filled region detection, achieving a 100% success rate on 40 tested images, largely owing to its dynamic control of the number of clusters.