• BMB Reports
• /
• 제43권4호
• /
• pp.257-262
• /
• 2010

The aim of work was to investigate changes of 7-ketocholesterol synthesis in alveolar macrophages in the dynamic of lung mechanical ventilation with injurious parameters. The goal of in vitro part of work was to observe influence of 7-ketocholesterol on iNOS and MIP1 $\beta$ production in bronchoalveolar lavage fluid (BALF) cells. We used 17 healthy domestic pigs randomly assigned into two treatment groups: group I with mechanical ventilation with physiological parameters; group II underwent injurious ventilation with high volume tidal (VT) and low positive end expiratory pressure (PEEP). Cells were analyzed for CYP27A1 protein and gene expression levels, 7-ketocholesterol production. In alveolar macrophages of group II, we obtained increase of production of CYP27A1 protein and 7-ketocholesterol, as well as the expression of the CYP27A1 gene at the 2nd hour of ventilation. In the in vitro experiments we show dose-dependent increase of MIP1 $\beta$ and decrease of CYP27A1, iNOS protein production after 7-ketocholesterol treatment.

• 한국전산유체공학회지
• /
• 제20권3호
• /
• pp.87-93
• /
• 2015

In this study, a numerical analysis was performed to simulate the thermal-hydraulic response of the secondary side of a steam generator(SG) model equipped with an orifice-type SG outlet flow restrictor to a main steam line break(MSLB) at a pressurized water reactor(PWR) plant. The SG analysis model includes the SG upper steam space and the part of the main steam pipe between the SG outlet and the broken pipe end. By comparing the numerical calculation results for the present SG model to those obtained for a simple SG model having no flow restrictor, the effects of the flow restrictor on the thermal-hydraulic response of SG to the MSLB were investigated.

• 대한기계학회:학술대회논문집
• /
• 대한기계학회 2004년도 추계학술대회
• /
• pp.1016-1021
• /
• 2004

The need for developing a mathematical model for pad-pivot friction in tilting pad proceeding bearings has been well-recognized, since previous experimental work about the performances of the bearings hypothesized that the friction in the bearings is closely related to their performances. Especially, the sliding friction between pad and pivot in the ball and socket type of the bearings can influence the performance of the bearing. We propose a mathematical model for pad-pivot friction in the ball and socket type, which considers the geometrics of the pad and pivot of the bearings, by assuming the sliding friction in the ball and socket bearing as Coulomb friction. By utilizing the proposed model for pad-pivot friction, we show the analysis of Reynolds equation and energy equation, which explain the thermo-hydrodynamic characteristics of tilting pad proceeding bearings, by taking into account the turbulence and inlet pressure building as well. The results of the study show that the performance of titling-pad proceeding bearings can be greatly influenced by the pad-pivot friction. In particular, we have shown that the analysis of the pad-pivot friction is useful to explain the static proceeding loci and the dynamic characteristics of the ball and socket type of the bearings. Furthermore, for a given operating condition, we can obtain various equilibrium states which satisfy the static equilibrium conditions, by considering the pad-pivot friction.

• 대한기계학회논문집
• /
• 제11권6호
• /
• pp.982-990
• /
• 1987

본 연구에서는 참고문헌(12)에서 배제된 머플러와 플래퍼밸브의 운동을 추가 시킴으로써 앞의 모델보다 실제장치에 근접시켜 보다 정확한 열적 및 동적거동을 예측 하고, 또한 컴퓨터 시뮬레이션의 수행시 계산시간을 줄여 정상운전상태의 결과를 얻고 자 한다.

• 대한기계학회논문집A
• /
• 제29권5호
• /
• pp.655-662
• /
• 2005

This paper investigates the improvement of accuracy and fatigue life of the developed counter pressurized microcellular gears of polyacetal. It is shown that the fatigue life and operational characteristics of the counter pressurized microcellular gears are more improved than conventional injection molded plastic gears by the dynamic gear durability test. For the cases of test sea.5. conventional injection molded sea.5(SGea.) and counter pressurized microcellular gears(CGear) are manufactured. Durability test is performed on both conventional lnjection molded gears and counter pressurized microcellular gears. Accuracy variation and operational characteristics on fatigue life, wear and tooth surface temperature of CGear and Scear are compared and represented. Operational characteristics of the proposed counter pressurized microcellular gears show a good result in this research. The durability limit of counter pressurized microcellular gears is also obtained, and represented by a function of unit load as well as by a function off-factor.

• 한국항공우주학회지
• /
• 제39권1호
• /
• pp.33-41
• /
• 2011

내삽형 부스터의 분리 운동 수학모델을 소개하였다. 부스터 분리 운동을 시뮬레이션 하기 위하여 3자유도 2물체 운동모델을 정립하였다. 유도탄과 공기중에 노출되는 부스터 영역의 공력모델을 개발하였다. 그리고, 부스터를 밀어내는 가스발생기도 모델링하였다. 이 모델을 시뮬레이션하기 위하여 유도탄이 부스터 분리과정에서 계속 1g 수평비행 조건을 유지한다는 가정을 세우고, 이를 기반으로 유도탄과 부스터간의 작용력을 분리 단계별로 정의 할 수 있었다. 단계 0: 초기, 단계 1: 선형이동, 단계 2: 자유운동. 이 시뮬레이션을 통하여 부스터를 안전하게 분리할 수 있는 유도탄의 마하수 및 고도의 범위를 제안할 수 있었다.

• 대한기계학회논문집A
• /
• 제27권5호
• /
• pp.657-665
• /
• 2003

Several interesting results were obtained from the flow visualization experiment in the accompanying paper, Part I. in the present study, Part II, a numerical study has been carried out to explain the detailed flow phenomena in micro-channel filling process. Hele-Shaw flow approximation was applied to the micro-channel geometry based on the small characteristic length. And surface tension effect has been introduced on the flow front as the boundary condition with the help of a dynamic contact angle concept between the melt front and the wall. A dimensional analysis for numerical results was carried out and a strong relationship between dimensionless pressure and Capillary number is obtained. The numerical analysis results are compared with the flow visualization experimental observations. And the numerical system developed in the present study seems to be able to predict the interesting micro-channel filling flow characteristics observed from experiments.

• 동력기계공학회지
• /
• 제20권1호
• /
• pp.50-56
• /
• 2016

This paper handled an investigation on the turbulent flow characteristics of three-dimensional small-size axial fan(SSAF) according to operating loads. Also, it was carried out by unsteady-state, incompressible and three-dimensional large eddy simulation(LES). The downstream flow type of SSAF is changed from axial flow to radial flow around the beginning of stall region at the aerodynamic performance curve. Axial mean velocity component largely grows around blade tip at the operating point of A to D, but transverse and vertical mean velocity components as well as Reynolds shear stresses highly develop around blade tip at the operating point of E to H. On the other hand, the peak value of turbulent kinetic energy developed around blade tip shows the highest at the operating point of E.

• International Journal of Quality Innovation
• /
• 제6권1호
• /
• pp.24-34
• /
• 2005

This research topic evaluates the effectiveness and importance of environmental protection in the 21st century in light of the increasing demand on the earth's natural resources and the pressures on economic and industrial development to provide dynamic power. As the world and our fellow citizens become more conscious of environmental protection, companies are under greater pressure whilst pursuing economic growth. Therefore, domestic manufacturers have been devoting efforts to promote environmental management. This research conducts survey using questionnaires on the operational performance of the manufacturers who have ISO 14000 series accreditation and certification. The survey considers five dimensions/functions within a manufacturer, financial management, human resources management, production management, and marketing management. A total of 35 indices are used for analysis of the effects that the location, history, industry, number of employees, amount of capital, and revenue may have on the performance. This research targets the manufacturers approved of ISO 14000 series certification by Environment Administration Association. The statistical methods deployed are descriptive statistics, T-test, and single factor analysis of variance used for analysis. The conclusions reveal that a certain level of performance has been achieved in every dimension. After T-test, all the indices have reached a significant level. The indications are that ISO 14001 benefits all manufacturers the level of benefits however varies from company to company.

• 한국도로학회논문집
• /
• 제7권1호
• /
• pp.39-47
• /
• 2005

최근 들어 섬유혼합토가 도로 및 철도의 성토노반, 기층재료로 활용되기 시작하여 섬유혼합토의 변형특성에 대한 연구가 필요하게 되었다. 본 논문에서는 공진주시험을 통하여 섬유혼합토의 거동특성과 보강효과를 평가하였다. 여러 가지 입도의 사질토에 폴리프로필렌(polypropylene) 재질의 단섬유(staple fiber)를 중량비 0.3%로 혼합하여 시료를 성형하였다. 섬유혼합토의 최대전단변형계수는 양입도일수록 증가해, 비혼합토에 비해 최대 30%까지 증가하였다. 양입도의 전단변형계수는 빈입도보다 모든 전단변형률 범위에서 구속압에 관계없이 더 커, 양입도일수록 보강효과가 좋은 것으로 평가되었다.