• 대한방사성의약품학회지
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• 제1권1호
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• pp.62-73
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• 2015

We developed an evans blue-indocyanine green-$^{99m}Tc$-human serum albumin conjugate for sentinel lymph node mapping and we describe its unique potential usage for clinical implications. This conjugate has combined the strengths of visible blue dye, near-infrared fluorescence and radioisotope into one single conjugate without any additional weakness/disadvantage. All the components of evans blue-indocyanine green-$^{99m}Tc$-human serum albumin are safe and of low cost, and they have already been clinically used. This conjugate was stable in the serum, it showed a long retention time in the lymphatic system and the lymph nodes showed a much higher signal-to-noise ratio after the conjugate was injected intradermally into the paw of mice. Both the single-photon emission computed tomography and near-infrared fluorescent images of the mice were successfully obtained at the same time as the excised sentinel lymph nodes showed blue color. The visual color, near-infrared fluorescence and gamma ray from this agent could be complementary for each other in all the steps of sentinel lymph node sampling: exploring and planning sentinel lymph node before excision with visualization of the exact sentinel lymph node location during an operation. Therefore, the triple modal agent will possibly be very ideal for sentinel lymph node mapping because of the high signal-to-noise ratio for non-invasive imaging and its complementary multimodal nature, easy preparation and safety. It is promising for clinical applications and it may have great advantages over the traditional single modal methods.

• Archives of Plastic Surgery
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• 제37권1호
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• pp.99-103
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• 2010

Purpose: Blow-out fractures are reduced through transcutaneous or transconjunctival incisions. But the field of orbital surgery is difficult due to lack of visualization of fracture site, blind dissection of orbital floor, susceptibility of injury of orbital structures. In these situations, the former technique of using an antral balloon catheter has advantages over other methods for reconstruction because of its rapidity, simplicity, and inexpensiveness. Furthermore, the antral balloon catheter allows not only elevation of the orbital bone fragment but also expansion of the maxillary sinus in cases where there is a fracture of its walls. But postoperative follow-up method using computed tomography is expensive. Hence, we report a simple and inexpensive follow-up method using radiopaque dye inflation. Methods: We performed endoscopic transantral approach in 5 cases of blow-out fracture under general anesthesia. To accomplish this technique, a rigid 4 mm, 0 or 30 degree angled endoscopy was inserted into the maxillary sinus. Inflation of the catheter started gradually, with 10 to 15 mL of saline mixed radiopaque dye (saline: dye, 5 : 1) by syringe and while observing the elevation of the fracture site with endoscope until a proper contour was reached. For the maintain of the position of fractured site, 12 French urinary balloon foley catheter were used in fracture site for 7 - 10 days. Results: Postoperative assessment was performed by means of clinical and simple radiographic examination to secure the catheter under the inferior orbital wall and in the maxillary sinus. No specific complications occurred related to this procedure. Results of the surgery and follow-up in all cases were satisfactory. Conclusion: It may be a better alternative to the conventional follow-up method, with less cost and effectiveness of the catheter patency. The advantages of using the urinary balloon foley catheter with the radiopaque dye include the following : it is safe, efficacy, simple, and especially low cost. On drawback of this method is the discomfort to the patient caused by the catheter during the treatment.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2005년도 추계 학술대회 논문집
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• pp.134-142
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• 2005

지하매질에서 핵종이동현상을 가시적으로 관찰할 수 있는 실험실규모 실험장치를 개발하여 이동실험을 수행하였다. 이 실험장치는 $50{\times}50cm$ 규모 화강암과 아크릴상층부로 구성되어있다. 실험에는 삼중수소, 음이온, 수착성양이온 뿐만 아니라 이동경로를 관찰할 수 있는 유기염료도 포함하였다. 시간에 따른 물질이동양태를 사진을 찍어 컴퓨터에 저장하였다. 또. 이동과정을 모사하고 단위공정별로 분석해 볼 수 잇는 이동모델도 개발하였다. 컴퓨터모사를 통해 균열내 흐름장에서 압력과 유속분포를 계산하고, 균열내 이동양태와 유출곡선을 계산해 실험결과와 비교 평가하였다.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2004년도 ICCAS
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• pp.68-71
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• 2004

Recently, a great deal of research and development of a fuel cell have been carried out to solve problems on the drain of fossil fuel, air pollution and global warning. In order to improve the efficiency of a fuel cell, it is necessary to clarify the flow in separator. In this study, distributions of velocity flow rate and pressure, and streamlines are examined in detail from numerical analysis with CFD code. In the experiment the distribution of flow rate is measured and flow in the each grooves of the separator is visualized by dye method changing Reynolds number. Furthermore, effects of size of the inlet and outlet manifolds and shape of ribs near the inlet outlet on the distributions of flow and pressure are examined.

• Journal of Advanced Marine Engineering and Technology
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• 제29권8호
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• pp.899-906
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• 2005

It is known that an oscillating airfoil can Produce a driving force through the generation of a reversed $K\'{a}rm\'{a}n$ vortex street, and this can be expected to be a new highly effective propulsion system. The wake formation behind the heaving airfoil was visualized and was measured using PIV systems We have been examined various conditions such as frequency number, amplitude in NACA 0010. As Strouhal number is greater than 0.08. wake profile with velocity deficit can be transformed into the wake with velocity excess After evaluating vortex center flow patterns in the wake investigated using tracking trajectories in temporal evaluation of the shedding vortices. We also Presented the experimental results on the unsteady vortices structure of the heaving airfoil at various parameters.

• 한국마린엔지니어링학회:학술대회논문집
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• 한국마린엔지니어링학회 2005년도 후기학술대회논문집
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• pp.31-32
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• 2005

It is known that an oscillating airfoil can produce a driving force through the generation of a reversed $K\acute{a}rm\acute{a}n$ vortex street, and this can be expected to be a new highly effective propulsion system. We have been examined various conditions such as frequency number, amplitude in NACA 0010. As Strouhal number is greater than 0.08, wake profile with velocity deficit can be transformed into the wake with velocity excess. We also presented the experimental results on the unsteady vortices structure of the heaving airfoil at various parameters.

• Journal of Mechanical Science and Technology
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• 제15권12호
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• pp.1853-1859
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• 2001

An experimental study is presented for a flow field in a two dimensional wavy channels by PIV. This flow has two major applications such as a blood flow simulation and the enhancement of heat transfer in a heat exchanger. While the numerical flow visualization results have been limited to the fully developed cases, existing experimental results of this flow were simple qualitative ones by smoke or dye streak test. Therefore, the main purpose of this study is to produce quantitative flow data for fully developed and developing flow regimes by the Correlation Based Correction PIV (CBC PIV) and to conjecture the analogy between flow characteristics and heat transfer enhancement with low pumping power. Another purpose of this paper is to examine the onset position of the transition and the global mixing, which results in transfer enhancement. PIV results on the Fully developed and developing flow in a wavy channel at Re=500, 1000 and 2000 are obtained. for the case Reynolds Number equals 500, the PIV results are compared with the finite difference numerical solution.

• 설비공학논문집
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• 제16권4호
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• pp.368-373
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• 2004

A flow field in a passage with periodically converging-diverging cross-section is investigated experimentally by PIV measurement. A tube with a sinusoidally wavy cross section is one of several devices employed for enhancing the heat and mass transfer efficiency due to turbulence promotion and unsteady vortical motion. While the numerical flow visualization results have been limited to the fully developed cases, existing experimental results of this flow were simple qualitative ones by smoke or dye streak test. Therefore, the main purpose of this study is to produce quantitative flow data for fully developed and transient flow regime by the Correlation Based Correction PIV (CBC PIV) and to conjecture the analogy between flow characteristics and heat transfer enhancement with low pumping power. Another purpose of this paper is to examine the onset position of the transition and the global mixing, which results in transfer enhancement. At Re=2000, evidences of the global mixing are captured at 2.5 wavy module through the variation of RMS values and instantaneous velocity plot.

• 한국윤활학회:학술대회논문집
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• 한국윤활학회 1998년도 제28회 추계학술대회
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• pp.166-174
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• 1998

The distribution of oil film thickness in piston were measured by induced fluorescence method. A Xe lamp was used as light source. Coumarine-6 was mixed with oil as the fluorescent dye. Fluorescent signal which is proportional to the oil film thickness was acquired by CCD camera and transmitted to the personal computer as video signal. In order to solve the problem of measurement system, irregular distribution and unstability of light intensity, as well as to know the relationship between the oil film thickness and output signal, three different calibration techniques were used. Motoring and firing tests were performed in a single cylinder research engine with transparent liner. By analyzing the oil film thickness converted from the photographed image, it was observed that each of three piston rings scrapes the oil both upward and downward and oil film thickness is not uniform horizontally at a given piston land. The amount of oil in each land was considerably affected by the engine load. It is thought that the blow-by gas blows the oil down to the crankcase.

• 한국유체기계학회 논문집
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• 제8권6호
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• pp.47-54
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• 2005

An oscillating foil can produce a driving force through the generation of a reversed $K\'{a}rm\'{a}n$ vortex street, and it can be expected to be a new highly effective propulsion system. A simple pitching foil model was made and it was operated within a water channel. The wake formation behind a pitching foil was visualized and unsteady fluid forces were measured using a 6-axis force sensor based on force and moment detectors. We have been examined various conditions such as reduced frequency, amplitude and pivot point in NACA 0010. The results showed that thrust coefficients increased with a reduced frequency. We also presented the experimental results on the characteristics of a pitching foil at various parameters.