• Journal of Radiopharmaceuticals and Molecular Probes
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• v.1 no.1
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• pp.62-73
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• 2015

We developed an evans blue-indocyanine green-$^{99m}Tc$-human serum albumin conjugate for sentinel lymph node mapping and we describe its unique potential usage for clinical implications. This conjugate has combined the strengths of visible blue dye, near-infrared fluorescence and radioisotope into one single conjugate without any additional weakness/disadvantage. All the components of evans blue-indocyanine green-$^{99m}Tc$-human serum albumin are safe and of low cost, and they have already been clinically used. This conjugate was stable in the serum, it showed a long retention time in the lymphatic system and the lymph nodes showed a much higher signal-to-noise ratio after the conjugate was injected intradermally into the paw of mice. Both the single-photon emission computed tomography and near-infrared fluorescent images of the mice were successfully obtained at the same time as the excised sentinel lymph nodes showed blue color. The visual color, near-infrared fluorescence and gamma ray from this agent could be complementary for each other in all the steps of sentinel lymph node sampling: exploring and planning sentinel lymph node before excision with visualization of the exact sentinel lymph node location during an operation. Therefore, the triple modal agent will possibly be very ideal for sentinel lymph node mapping because of the high signal-to-noise ratio for non-invasive imaging and its complementary multimodal nature, easy preparation and safety. It is promising for clinical applications and it may have great advantages over the traditional single modal methods.

• Archives of Plastic Surgery
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• v.37 no.1
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• pp.99-103
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• 2010

Purpose: Blow-out fractures are reduced through transcutaneous or transconjunctival incisions. But the field of orbital surgery is difficult due to lack of visualization of fracture site, blind dissection of orbital floor, susceptibility of injury of orbital structures. In these situations, the former technique of using an antral balloon catheter has advantages over other methods for reconstruction because of its rapidity, simplicity, and inexpensiveness. Furthermore, the antral balloon catheter allows not only elevation of the orbital bone fragment but also expansion of the maxillary sinus in cases where there is a fracture of its walls. But postoperative follow-up method using computed tomography is expensive. Hence, we report a simple and inexpensive follow-up method using radiopaque dye inflation. Methods: We performed endoscopic transantral approach in 5 cases of blow-out fracture under general anesthesia. To accomplish this technique, a rigid 4 mm, 0 or 30 degree angled endoscopy was inserted into the maxillary sinus. Inflation of the catheter started gradually, with 10 to 15 mL of saline mixed radiopaque dye (saline: dye, 5 : 1) by syringe and while observing the elevation of the fracture site with endoscope until a proper contour was reached. For the maintain of the position of fractured site, 12 French urinary balloon foley catheter were used in fracture site for 7 - 10 days. Results: Postoperative assessment was performed by means of clinical and simple radiographic examination to secure the catheter under the inferior orbital wall and in the maxillary sinus. No specific complications occurred related to this procedure. Results of the surgery and follow-up in all cases were satisfactory. Conclusion: It may be a better alternative to the conventional follow-up method, with less cost and effectiveness of the catheter patency. The advantages of using the urinary balloon foley catheter with the radiopaque dye include the following : it is safe, efficacy, simple, and especially low cost. On drawback of this method is the discomfort to the patient caused by the catheter during the treatment.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2005.11a
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• pp.134-142
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• 2005

The experimental setups for flow visualization and processes identification in laboratory scale (so cal led Flow Lab.) has developed to get ideas and answer fundamental questions of flow and migration in geologic media. The setup was made of a granite block of $50{\times}50cm$ scale and a transparent acrylate plate. The tracers used in this experiments were tritiated water, anions, and sorbing cations as well as an organic dye, eosine, to visualize migration paths. The migration plumes were taken with a digital camera as a function of time and stored as digital images. A migration model was also developed to describe and identify the transport processes. Computer simulation was carried out not only for the hydraulic behavior such as distributions of pressure and flow vectors in the fracture but also for the migration plume and the elution curves.

• 제어로봇시스템학회:학술대회논문집
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• 2004.08a
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• pp.68-71
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• 2004

Recently, a great deal of research and development of a fuel cell have been carried out to solve problems on the drain of fossil fuel, air pollution and global warning. In order to improve the efficiency of a fuel cell, it is necessary to clarify the flow in separator. In this study, distributions of velocity flow rate and pressure, and streamlines are examined in detail from numerical analysis with CFD code. In the experiment the distribution of flow rate is measured and flow in the each grooves of the separator is visualized by dye method changing Reynolds number. Furthermore, effects of size of the inlet and outlet manifolds and shape of ribs near the inlet outlet on the distributions of flow and pressure are examined.

• Journal of Advanced Marine Engineering and Technology
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• v.29 no.8
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• pp.899-906
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• 2005

It is known that an oscillating airfoil can Produce a driving force through the generation of a reversed $K\'{a}rm\'{a}n$ vortex street, and this can be expected to be a new highly effective propulsion system. The wake formation behind the heaving airfoil was visualized and was measured using PIV systems We have been examined various conditions such as frequency number, amplitude in NACA 0010. As Strouhal number is greater than 0.08. wake profile with velocity deficit can be transformed into the wake with velocity excess After evaluating vortex center flow patterns in the wake investigated using tracking trajectories in temporal evaluation of the shedding vortices. We also Presented the experimental results on the unsteady vortices structure of the heaving airfoil at various parameters.

• Proceedings of the Korean Society of Marine Engineers Conference
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• 2005.11a
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• pp.31-32
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• 2005

It is known that an oscillating airfoil can produce a driving force through the generation of a reversed $K\acute{a}rm\acute{a}n$ vortex street, and this can be expected to be a new highly effective propulsion system. We have been examined various conditions such as frequency number, amplitude in NACA 0010. As Strouhal number is greater than 0.08, wake profile with velocity deficit can be transformed into the wake with velocity excess. We also presented the experimental results on the unsteady vortices structure of the heaving airfoil at various parameters.

• Journal of Mechanical Science and Technology
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• v.15 no.12
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• pp.1853-1859
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• 2001

An experimental study is presented for a flow field in a two dimensional wavy channels by PIV. This flow has two major applications such as a blood flow simulation and the enhancement of heat transfer in a heat exchanger. While the numerical flow visualization results have been limited to the fully developed cases, existing experimental results of this flow were simple qualitative ones by smoke or dye streak test. Therefore, the main purpose of this study is to produce quantitative flow data for fully developed and developing flow regimes by the Correlation Based Correction PIV (CBC PIV) and to conjecture the analogy between flow characteristics and heat transfer enhancement with low pumping power. Another purpose of this paper is to examine the onset position of the transition and the global mixing, which results in transfer enhancement. PIV results on the Fully developed and developing flow in a wavy channel at Re=500, 1000 and 2000 are obtained. for the case Reynolds Number equals 500, the PIV results are compared with the finite difference numerical solution.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.16 no.4
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• pp.368-373
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• 2004

A flow field in a passage with periodically converging-diverging cross-section is investigated experimentally by PIV measurement. A tube with a sinusoidally wavy cross section is one of several devices employed for enhancing the heat and mass transfer efficiency due to turbulence promotion and unsteady vortical motion. While the numerical flow visualization results have been limited to the fully developed cases, existing experimental results of this flow were simple qualitative ones by smoke or dye streak test. Therefore, the main purpose of this study is to produce quantitative flow data for fully developed and transient flow regime by the Correlation Based Correction PIV (CBC PIV) and to conjecture the analogy between flow characteristics and heat transfer enhancement with low pumping power. Another purpose of this paper is to examine the onset position of the transition and the global mixing, which results in transfer enhancement. At Re=2000, evidences of the global mixing are captured at 2.5 wavy module through the variation of RMS values and instantaneous velocity plot.

• Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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• 1998.10a
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• pp.166-174
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• 1998

The distribution of oil film thickness in piston were measured by induced fluorescence method. A Xe lamp was used as light source. Coumarine-6 was mixed with oil as the fluorescent dye. Fluorescent signal which is proportional to the oil film thickness was acquired by CCD camera and transmitted to the personal computer as video signal. In order to solve the problem of measurement system, irregular distribution and unstability of light intensity, as well as to know the relationship between the oil film thickness and output signal, three different calibration techniques were used. Motoring and firing tests were performed in a single cylinder research engine with transparent liner. By analyzing the oil film thickness converted from the photographed image, it was observed that each of three piston rings scrapes the oil both upward and downward and oil film thickness is not uniform horizontally at a given piston land. The amount of oil in each land was considerably affected by the engine load. It is thought that the blow-by gas blows the oil down to the crankcase.

• The KSFM Journal of Fluid Machinery
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• v.8 no.6 s.33
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• pp.47-54
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• 2005

An oscillating foil can produce a driving force through the generation of a reversed $K\'{a}rm\'{a}n$ vortex street, and it can be expected to be a new highly effective propulsion system. A simple pitching foil model was made and it was operated within a water channel. The wake formation behind a pitching foil was visualized and unsteady fluid forces were measured using a 6-axis force sensor based on force and moment detectors. We have been examined various conditions such as reduced frequency, amplitude and pivot point in NACA 0010. The results showed that thrust coefficients increased with a reduced frequency. We also presented the experimental results on the characteristics of a pitching foil at various parameters.