• Restorative Dentistry and Endodontics
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• 제23권1호
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• pp.443-460
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• 1998

The purpose of this study was to estimate the changes of tensile bond strength according to the difference in lining materials and lining area. Seventy non-carious extracted human molars were used in the present study, and they were randomly assigned into 2 experimental groups according to the difference in lining materials. Each experimental group was subdivided into 3 groups according to the difference in lining area. Circular cavities were prepared on the dentin surface to a diameter of 1.5mm, 2.0mm, 2.5mm and the prepared cavities were filled with Fuji II LC( Glass Ionomer Cement : GIC) or Dycal. Dentin specimens without circular cavity were used as control group. The primer and bonding agent of All-Bond 2 and composite resin (Z-100, 3M Dental Products, U. S. A.) were applied to the exposed dentin surface with or without lining. Tensile bond strengths for the experimental specimens were then measured. To examine the interface between dentin and liner & between liner and composite resin, two specimens from each group were fabricated and observed under the SEM. The results were as follows. 1. Tensile bond strength for the specimens lined with GIC was higher than that for specimens lined with Dycal. However, there was no significant difference between two groups(p>0.05). 2. Tensile bond strength for the specimens lined with GIC in a diameter of 1.5mm(GIC-1.5mm lining group) was statistically higher than that for the GIC-2.0mm lining group and GIC-2.5mm lining group(p<0.05). 3. Tensile bond strength for the specimens lined with Dycal in a diameter of 2.5mm (Dycal-2.5mm lining group)was statistically lower than that for Dycal-1.5mm lining group and Dycal-2.0mm lining group(p<0.05). 4. It was possible to observe the good adhesion of the resin composite to the GIC and the presence of a fissure between GIC and dentin all along the interface. Interfacial gaps of 7.2-$72.2{\mu}m$ between GIC and dentin were observed. The interfacial gap between GIC and dentin at the cavity base was greater. However, the gap was gradually decreased toward the occlusal portion. 5. It was possible to observe the poor adhesion of the resin composite to the Dycal. The detachment of Dycal was occurred all along the composite resin-Dycal interface, and the gaps of 2.0-$30.1{\mu}m$ were formed. In all the specimens, polymerization shrinkage of resin composite caused the detachment of Dycal from the body of Dycal. At a Dycal-dentin interface. it was possible to observe the good adhesion. but poor adhesion with interfacial gap of 2.9-$26.8{\mu}m$ was observed partially.

• Restorative Dentistry and Endodontics
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• 제10권1호
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• pp.93-101
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• 1984

The experimental study was made to investigate the effect of the "Heliosit" composite resin on the dental pulp. The 36 class V cavities were prepared on the healthy permanent teeth of 3 days, and were divided into 5 groups and filled with the experimental filling materials. Control group: Zinc Oxide-Eugenol cement filling Experimental groups: Group 1: Dentin Adhesit application & Heliosit filling with or without dycal base Group 2: Heliosit filling with or without dycal base Group 3: Durafill filling with dycal base Group 4: Hipol filling with dycal base Animals were sacrificed after 1 weeks, 2 weeks, and 4 weeks following operation. The teeth were decalcified, sectioned and stained with hematoxylin and eosin. The results obtained form this study were as follows: 1. All experimental group showed slight pulp response. 2. Dentin Adhesit group showed minimal pulp response in both dycal bases and no base cases. 3. In group 2, mild pulp response was found in early stage and repairing process was found as the time elapsed. In no base cases, healing process was delayed slightly. 4. There was little difference in the result among Heliosit group, Durafill group and Hipol group.

• Restorative Dentistry and Endodontics
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• 제36권5호
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• pp.397-408
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• 2011

연구목적: 이 연구에서는 mineral trioxide aggregate 제재인 white ProRoot MTA (wMTA)와 수산화칼슘 제재인 Dycal을 인간치수세포에 적용한 후 치수세포의 분화와 증식, 석회화, 신생혈관형성(angiogenesis) 그리고 염증에 관여하는 유전자들의 발현 변화를 비교하였다. 연구 재료 및 방법: 실험군은 wMTA와 Dycal을 테플론 튜브(내경 10 mm, 길이 1 mm)에 담아 4시간 경화시킨 후 일차세포배양한 인간치수세포에 적용하였고, 대조군은 빈 튜브만을 적용하였다. 3시간, 6시간, 9시간, 24시간 후 total RNA를 추출하고 oligonucleotide microarray 방법을 통하여 유전자 발현 양상을 분석하였다. 위의 결과를 역전사 중합효소 연쇄반응(reverse transcriptase polymerase chain reaction)으로 재확인하였다. 결과: wMTA를 적용한 실험군에서 24,546개의 유전자 중 43개 유전자의 발현이 2배 이상 증가하였으며(예. BMP2, FOSB, THBS1, EDN1, IL11, COL10A1, TUFT1, HMOX1) 25개 유전자의 발현이 50% 이하로 감소하였다(예. SMAD6, TIMP2, DCN, SOCS2, CEBPD, KIAA1199). Dycal을 적용한 실험군에서 239개 유전자의 발현이 2배 이상 증가하였으며(예. BMP2, BMP6, SMAD6, IL11, FOS, VEGFA, PlGF, HMOX1, SOCS2, CEBPD, KIAA1199) 358개 유전자의 발현이 50% 이하로 감소하였다(예. EDN1, FGF). 결론: wMTA를 적용한 치수세포에서는 분화와 증식 그리고 석회화에 관여하는 유전자들의 변화가 관찰되었다. Dycal을 적용한 치수세포에서는 분화와 증식 그리고 신생혈관형성에 관여하는 유전자들의 변화가 관찰되었다. 또 Dycal이 염증에 관여하는 유전자들을 더 많이 발현시키는 양상을 보였다.

• Restorative Dentistry and Endodontics
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• 제34권3호
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• pp.192-198
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• 2009

이번 연구는 치근 천공의 치료 재료인 white mineral trioxide aggregate (MTA)를 흔히 사용되는 calcium hydroxide liner ($Dycal^{(R)}$), glass ionomer cement (GIC), 그리고 MTA와 유사한 성분을 가진 Portland cement와 세포독성 실험으로 생체 친화성을 평가하는 것이다. 세포독성의 정도는 MG-63 세포를 이용해 주사전자 현미경적 관찰과 수용성 tetrazolium salt를 이용한 흡광도를 측정 (XTT assay)하여 평가하였다. SEM 관찰에서, 1일과 3일째 모두에서 GIC와 MTA, Portland cement 표면에서는 잘 부착된 세포를 보여주었다. 반면에, Dycal 표면의 세포들은 둥글고 부착되지 않은 양상을 보여 주었다. XTT assay에서는 Dycal을 제외한 모든 재료에서 유사하게 높은 세포 활성도를 보여주었으며, 이는 SEM 관찰 소견과 일치하였다. 이번 연구는 MTA가 생체친화적인 재료라는 견해를 뒷받침한다. 또한 Portland cement와 GIC에서도 MTA와 유사한 세포반응을 보여주었다.

• Restorative Dentistry and Endodontics
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• 제4권1호
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• pp.11-16
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• 1978

This experimental study was made to investigate the effect of the "Hi-Pol" composite resin on the human dental pulp. 38 cavities of healthy permanent teeth were divided into 5 groups which were used as experimental materials. Group 1: Zinc Oxide-Euginol paste was applied to the cavities as controls $\cdots\;\cdots8$ cases Group 2: "Hi-Pol"*filling with Dycal** base $\cdots\;\cdots9$ cases Group 3: "Hi-Pol" filling without Dycal base $\cdots\;\cdots9$ cases Groud 4: Adaptic*** filling with Dycal base $\cdots\;\cdots6$ cases Group 5: Adaptic filling without Dycal base $\cdots\;\cdots6$ cases The treated teeth were extracted after 1 week, 2 weeks, 3 weeks and 4 weeks and processed for histological study. The results obtained from this experimental study were as follows; 1. The controls applied zinc oxide-eugenol showed the minimal pulp response and group 3 and group 5 showed the most severe pulp response. 2. In group 3 and group 5, the severity of pulp response increased in intensity according to the time elapsed. 3. In group 2 and group 4, the mild pulp response was found in earlier stage and the repairing process could be observed in later stage. * Boo-Pyung Co., Korea ** L. D. Caulk Co., Milford, Del. 19963 *** Johnson and Johnson Co., New Brunswick, NJ 08903.

• Restorative Dentistry and Endodontics
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• 제14권2호
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• pp.77-97
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• 1989

The purpose of this study was to observe the effect of ${\beta}GP$ in the remaining dental pulp tissue after pulpotomy in the dogs' teeth. For vital pulpotomy, 72 dogs' teeth were used and class V cavities were prepared and the pulps were amputated. ZOE and Dycal (Caulk Co., USA) were placed over the amputated tissue and cavities were sealed with ZOE cement in the control group. In the experimental group, ${\beta}GP$, ${\beta}GP$-ZOE, ${\beta}GP$-Dycal were placed over the exposed pulp tissues respectively. Dogs were sacrificed after 1, 2 and 4 weeks following the operations and the teeth were decalcified in the nitric acid, sectioned and stained with HE for light microscopic examination. For electron microscopic examination, specimens were made after 2 and 4 weeks following the operation. A comparative microscopic examination revealed as follows. 1. The dentin bridge was formed continuously due to osteodentin in the ${\beta}GP$-Dycal group at the 2nd week, the dentin bridge composed of osteodentin and tubular dentin was observed at the 4th week. 2. Osteodentin formation was vigorously in the ${\beta}GP$-Dycal than in the Dycal group. 3. In the surface of osteodentin the osteodentinoblasts showing vivid synthetic activity were observed and the matrix vesicles were presented during calcification of osteoid dentin matrix. 4. The dentin bridge formation was not observed in ${\beta}GP$ group and ${\beta}GP$-ZOE group.

• 대한치과의사협회지
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• 제11권11호
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• pp.711-715
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• 1973

The author studied histopathologically on the pulpal response of Blendant, Blendant lined with Dycal, silicate cement and direct resin in dog's teeth. The results were as follows ; 1. Blendant induced pulpal irritations but the intensity of irritations were less severe than Silicate cement and Orient. 2. At the postoperative interval of 4 weeks, Silicate cement produced severe pulpal response but the severe response caused by Orient was subsided. 3. Blendant lined with Dycal showed only slight or moderate pulpal response.

• 대한치과의사협회지
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• 제22권9호통권184호
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• pp.803-811
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• 1984

The purpose of this study was to research how temporary cementation effected on the bond strength of permanent cementation. Zinc phosphate, polycarboxylate and EBA ZOE cements were used as permanent cements, and as temporary cements Nogenol, Tempak and Dycal were used. The ninety six (96) specimens were prepared to measure the bond strength of permanent cements after treated with temporary cements for one week. The tensile stregths were measured with an Instron Universal Test Machine. The results of this study were obtained as follows: 1. With zinc phosphate cement, there was a tendency that the bond strengths of the group of temporarily cemented with Nogenol were increased, meanwhile they were decreased a little in the groups of Dycal and Tempak than those of the control group. 2. With polycarboxylate cement, there was a tendency that the bond strengths of the Control group were higher than those of experimental groups and they were decreased in order of Tempak, Noginol, and Dycal. 3. With EBA ZOE cement, there was a tendency that the bond strengths of the group of temporarily cemented with Tempak were increased a little, meanwhile they were decreased a little in the groups of Nogenol and Dycal than those of the Control group. 4. Among the permanent cements, the bond strengths of polycarbosylate cement were the highest and were followed in order of zinc phosphate cement and EBA ZOE cement.

• Restorative Dentistry and Endodontics
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• 제45권1호
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• pp.10.1-10.8
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• 2020

Objectives: This study aimed to compare the shear bond strength (SBS) of a self-adhering flowable composite (Dyad Flow) and a bulk-fill flowable composite (Smart Dentin Replacement [SDR]) to several pulp-capping materials, including MTA Plus, Dycal, Biodentine, and TheraCal. Materials and Methods: Eighty acrylic blocks with 2-mm-deep central holes that were 4 mm in diameter were prepared and divided into 2 groups (n = 40 each) according to the composite used (Dyad Flow or SDR). They were further divided into 4 sub-groups (n = 10 each) according to the pulp-capping agent used. SBS was tested using a universal testing machine at a crosshead speed of 1 mm/min. Data were analyzed using 2-way analysis of variance. A p value of < 0.05 was considered to indicate statistical significance. Results: A statistically significant difference (p = 0.040) was found between Dyad Flow and SDR in terms of bond strength to MTA Plus, Dycal, Biodentine, and TheraCal. Conclusions: Among the 8 sub-groups, the combination of TheraCal and SDR exhibited the highest SBS.

• Restorative Dentistry and Endodontics
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• 제7권1호
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• pp.107-115
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• 1981

The purpose of this investigation was to study histopathological chronology and differences of the proprietary pulpcapping agents. One hundred eighty molars from thrity rats (Srague-Dawley species), weighing about 130gm, were divided into six groups. Cavities were prepared in their maxillary molars under intraperitoneal anesthesia with Secobarbital. The cavities in the right first and second molars were filled with Dycal$^{(R)}$ and the left ones were with Cavitec$^{(R)}$. Each group of rats were sacrificed at the intervals of 1, 3, 5, 7, 14 and 21 days following operation. The rats were decapituated, and the jaws were fixed in 10% neutral buffered formalin. Then the specimens were decalcified, embedded in paraffin or celloid, and sectioned at 6-8 ${\mu}$ in thickness through the cavities included and pulp mesiodistally. They were stained with Hematoxylin-Eosin and examined by lightmicroscope. The results were as follow: 1. The pattern of pulp healing was dependent upon the presence and character of the pulpcapping agents above. 2. Dentin bridge formation as a sign of pulp healing occurred in the 14 days after operation. 3. Dycal$^{(R)}$ reparation appeared to favor pulp bealing rather than Cavitec$^{(R)}$ preparation. 4. In the odontoblastic layer and pulp tissue specific vaculoes were showed at the 3, 5 and 7 days of the Dycal filling.