• 한국전자파학회논문지
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• 제13권8호
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• pp.834-842
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• 2002

임의 모양의 완전도체의 전자파 산란을 해석하기 위하여 모멘트 방법을 이용하였다. GID(Graphic Interface Design)툴을 이용하여 설계된 금속 도체의 표면은 서로 다른 모양의 삼각패치로 모델링 되었다. 도체 표면전류는 삼각패치의 벡터 기저함수로 확장되었다. 관측점과 전원점이 동일 삼각패치에 위치할 때, 삼각패치의 특이점 적분은 Duffy 방법을 이용하여 특이점이 없는 적분으로 변환이 가능하였고, 변환된 특이점 항들은 1차원의 가우시안 구적법을 이용하여 간단하게 계산되어질 수 있었다. 특이점을 제외한 적분들은 2차원 가우시안 구적법으로 계산되었다.

• Parasites, Hosts and Diseases
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• 제39권2호
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• pp.143-150
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• 2001

The present study was designed to investigate polymorphism in Duffy binding protein (DBP) gene of Plasmodium vivax isolates of Korea. Thirty samples were obtained from P. vivax patients in Yonchon-gun, Kyonggi-do in 1998. The PCR products of the samples were subjected to sequencing and hybridization analyses of the regions II and IV of P. vivax DBP gene. Two genotypes, SK-1 and SK-2, were identified on the basis of amino acid substitution and deletion. The genotype of 10 isolates was SK-1 and that of 20 isolates was SK-2. Most of the predicted amino acids in the region ll of DBP gene were conserved between the Korean isolates and Belem strain except for 4-5 amino acid substitutions. In the region W of DBP, a 6-bp insert that was shown in the Sal-1 allele type was found in SK-1, and a 27-bp insert that was shown in the Papua New Guinea allele type was found in SK-2. In conclusion, the present findings suggest that two genotypes of P. vivax coexist in the endemic area of Korea.

• 대한임상검사과학회지
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• 제50권3호
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• pp.354-358
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• 2018

수혈 준비 시 비예기 항체 선별검사를 통한 항체의 유무와 그 종류를 아는 것은 매우 중요하다. DiaMed-ID시스템을 이용하여 대전지역 일개 대학병원에 2016년 1월부터 2017년 12월까지 2년 동안 의뢰된 비예기 항체 선별검사 양성자 중에서 항체동정은 55명에서만 되었고 주로 여성에서 자주 동정되었다. Rh 36예(65.5%), Lewis 7예(12.7%), Kidd 4예(7.3%), Duffy 4예(7.3%), MNSs 3예(5.5%), Rh+Kidd 복합 1예(1.8%)가 동정되었는데, Rh 계열은 Anti-E 19예(34.5%), Anti-E/-c 4예(7.3%), Anti-C/-e 4예(7.3%), $Anti-E/-c/-Jk^b$ 1예(1.8%)가, Lewis 계열은 $Anti-Le^a$ 3예(5.5%), $Anti-Le^b$ 3예(5.5%), Kidd 계열은 $Anti-Jk^a$ 1예(1.8%), $Anti-Jk^b$ 3예(5.5%)가 동정되었다. Duffy와 MNSs 계열은 각각 $Anti-Fy^a$ 1예(1.8%), $Anti-Fy^b$ 3예(5.5%), Anti-M 2예(3.6%), Anti-S 1예(1.8%)가 동정되었다. 최근 대전의 비예기 항체 빈도와 분포가 반영된 이 연구는 효율적인 수혈준비에 도움이 될 것이다.

• Journal of Microbiology and Biotechnology
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• 제17권10호
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• pp.1670-1674
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• 2007

Duffy binding protein (DBP) plays a critical role in Plasmodium vivax invasion of human red blood cells. We previously reported a single-chain antibody fragment (scFv) that was specific to P. vivax DBP (PvDBP). However, the stabilization and the half-life of scFvs have not been studied. Here, we investigated the effect of PEGylated scFvs on their biological activity and stability in vitro. SDS-PAGE analysis showed that three clones (SFDBII-12, -58, and -92) were formed as monomers (about 70 kDa) with PEGylation. Clone SFDBII-58 gave the highest yield of PEGylated scFv. Binding analysis using BIAcore between DBP and scFv showed that both SFDBII-12 and -58 were decreased approximately by two folds at the level of binding affinity to DBP after PEGylation. However, the SFDBII-92 clone still showed a relatively high level of binding affinity ($K_D=1.02{\times}10^{-7}\;M$). Binding inhibition assay showed that PEGylated scFv was still able to competitively bind the PvDBP and playa critical role in inhibiting the interactions between PvDBP protein expressed on the surface of Cos-7 cells and Duffy receptor on the surface of erythrocytes. When both scFvs and their PEGylated counterparts were exposed to trypsin, scFv was completely degraded only after 24 h, whereas 35% of PEGylated scFvs remained intact, maintaining their stability against the proteolytic attack of trypsin until 72 h. Taken together, these results suggest that the PEGylated scFvs retain their stability against proteolytic enzymes in vivo, with no significant loss in their binding affinity to target antigen, DBP.

• Communications for Statistical Applications and Methods
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• 제4권1호
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• pp.161-165
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• 1997

양적속성의 추정을 위한 확률화응답기법은 Greenberg et al.(1971)로부터 시작된다. 이후 새로운 방법에 대한 제시(Dalenius와 Vitale(1974)) 및 분포함수에 대한 추정(Duffy와 Waterton(1984))등이 연구되어 오고 있다. 본 연구에서는 2단계 확률화응답기법을 이용하여 양적속성을 추정하는 방법을 제시하고 이의 효율성 비교를 행해 보고자 한다.

• 한국결정성장학회지
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• 제5권2호
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• pp.181-188
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• 1995

3차 비선형광학 재료를 설계하기 위해 단성분 산화물에서의 산소의 평균 전자분극률과 광학 염기도를 굴절율, 에너지 갭의 각기 다른 물성을 통해 산출하였다. Lorentz-Lornez식과 Duffy 의 반실험식을 도입하여 산소의 평균 전자분극율과 광학 염기도를 두가지 다른 물성으로부터 계산하여 비교하였다. 처음으로 독립적인 초기값에서 계산한 각각의 산소의 평균 전자분극률과 광학 염기도 사이에 좋은 상응관계가 있음을 확인하였다.

• International Journal of Naval Architecture and Ocean Engineering
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• 제12권1호
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• pp.644-644
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• 2020

• International Journal of Naval Architecture and Ocean Engineering
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• 제11권2호
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• pp.750-764
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• 2019

• 한국실내디자인학회:학술대회논문집
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• 한국실내디자인학회 2004년도 추계학술발표대회 논문집
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• pp.46-49
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• 2004

A contemporary office space is changed by the transformation to an information-oriented society from an industrial society. A contemporary office space is recognized as an interactional space which is more of a mental and psychological space than a physical space. I studied the basic concept of an office space and the relationship of a social change and an office space on this study. I also studied the concept of an ubiquitous computing and the relationship of an ubiquitous computing and an office space. Through this study, we can establish the new concept of an office space to be applied to an ubiquitous concept. The ubiquitous concept of an office space will be brought into a new prototype of an office space, and then there is no more important to a physical place and time. The office space must be redesigned by an ubiquitous space nowadays.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2002년도 하계종합학술대회 논문집(1)
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• pp.191-194
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• 2002

We analyzed radiation characteristics of dipole antenna in a lossy 9round with conducting object located above ground. Electric field integral equation is used to solve the problem. In this integral equation, GPOF(Generalized Pencil of Function) method is applied to derive the closed form of the electric field due to a current source. Surface current on a conductor is expanded with a well-known vector triangle basis function. The singular integration of a triangle patch is transformed to the non-singular integration by Duffy's method. This transformed non-singular integration is easily calculated by using one-dimensional Gaussian quadrature rule, instead of usual closed form evaluation.