• 제목/요약/키워드: Duct area

검색결과 233건 처리시간 0.026초

Comparison of Histopathological Changes on the Three Drugs of Carbon Tetrachloride, Dimethylnitrosamine, Thioacetamide, and Bile Duct Ligation used for Induction of Liver Fibrosis in Rat

  • Kim, Jung-Hun;Park, Mi-Jung;Kim, Yo-El;Kim, Jin-Yeong;Sin, Jin-Hee;Park, Su-Young;Jekal, Seung-Joo
    • 대한임상검사과학회지
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    • 제43권4호
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    • pp.194-204
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    • 2011
  • This study was carried out to compare the histopathological differences of liver lesions in carbon tetrachloride ($CCI_4$), dimethylnitrosamine (DMN), thioacetamide (TAA) and bile duct ligation (BDL)-induced rats. $CCl_4$, DMN and TAA were administered intraperitoneally and conducted bile duct ligation for 4 weeks to induce hepatic fibrosis. Indices of liver cell injury (steatosis, hydropic degeneration, bile duct hyperplasia, hemorrhage & hemosiderin deposition), the extent of liver fibrosis (fibrotic area) and the rate of regeneration (number of PCNA-positive cells) were investigated in each group. Liver tissues were stained with hematoxylin-eosin (HE), sirius red, prussian blue and immunostained with ${\alpha}$-smooth muscle actin (${\alpha}$-SMA), transforming growth factor-${\beta}1$ (TGF-${\beta}1$), proliferative cell nuclear antigen (PCNA), and quantified using a computerized image analysis system. Liver cell steatosis was significantly increased in $CCl_4$ and TAA groups, and hydropic degeneration and bile duct hyperplasia were significantly increased in TAA and BDL groups when compared with that in normal control, respectively. Fibrosis area was significantly increased in all four groups, especially in $CCl_4$ group. Correlation between ${\alpha}$-SMA and TGF-${\beta}1$ expressions in four groups was good. Hemorrhage area in liver parenchyma was significantly increased in DMN group only when compared with that in normal control, while hemosiderin deposition area was significantly increased in TAA and BDL groups as well as DMN group. The Number of PCNA-positive cells was significantly increased in all four groups, especially in TAA group. These results indicate that the duration and methods of hepatotoxic drug treatment are very important factors to make plans for animal experimentation on the induction of hepatic fibrogenesis in rats.

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산업용 연돌 발파해체에서 붕괴거동에 관한 수치해석적 연구 (Numerical Analysis of Collapse Behavior in Industrial Stack Explosive Demolition)

  • 전푸른;민경조;;박훈;석철기;송태협;장경필;조상호
    • 화약ㆍ발파
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    • 제41권3호
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    • pp.62-72
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    • 2023
  • 1970년대 산업화에 따른 플랜트 구조물이 노후화됨에 따라 구조적 기능을 상실해 발파 해체 공법을 활용한 해체 철거 수요가 증가하고 있다. 발파 해체공법은 기계식 해체공법에 비해 해체 공기가 짧아 환경공해 발생 노출 시간을 최소화할 수 있지만 잘못된 발파 설계 및 시공 계획에 따른 붕괴거동의 실패는 안전성에 매우 큰 위험을 유발한다. 따라서 붕괴거동 모사를 통해 최적의 발파 해체 조건과 이에 따른 영향을 고려하는 것이 중요하다. 본 연구에서는 Finite element method (FEM)와 Discrete element method (DEM)의 장점을 활용해 구축된 3-D Combined finite discrete element method (FDEM) 코드 기반 3-D DFPA 를 적용해 (구)서천화력발전소의 연돌 구조물에 대한 해체 모사를 수행하였으며 실제 구조물의 연돌 구조물 발파해체의 붕괴거동과 비교 분석하였다. 수치 모사 결과, 실제 구조물과 붕괴 거동 및 붕괴 완료 시간이 동일하게 나타났다. 또한, 발파구간 개구부 상부에 위치한 후드부의 크기가 연돌의 붕괴거동에 미치는 영향을 분석하기 위해 후드부의 면적을 조정하여 해체 모사를 수행하고 균열 발생 양상 및 z-방향 변위 곡선을 통해 비교 분석하였다. 분석 결과, 후드부의 면적이 증가함에 따라 하중을 지지하는 면적이 줄어들고 그에 따른 균열 발생 증가 및 전도 시간 감소를 확인하였다.

INLET S-DUCT 내부흐름의 전압력 편차에 대한 실험 연구 (Experimental study of total pressure distortion in inlet S-ducts)

  • 김무도;정상영;김요섭
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 1987년도 한국자동제어학술회의논문집; 한국과학기술대학, 충남; 16-17 Oct. 1987
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    • pp.541-546
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    • 1987
  • An experimental study has been conducted to investigate the suction performance of a designed inlet. Total pressure distortion in the inlet S-duct was measured and the effect of lip thickness and throat area was analyzed. The volume flow rate of air into the turbojet engine was controlled to observe the effect of engine RPM to the total pressure distortion. The pressure data from 36 air tubes were obtained using scanivalve, pressure transducer, and visicoder system.

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개에서 턱밑샘관 및 혀밑샘관의 결찰이 턱밑샘에 미치는 영향 (Effects of Ligature of Mandibular Gland and Sublingual Gland on the Mandibular Gland in Dogs)

  • 황학균;김명철
    • 한국임상수의학회지
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    • 제16권1호
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    • pp.57-64
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    • 1999
  • It was performed to evaulate the effects of occlusion of mandibular gland and sublingual gland on the mandibular gland in dogs. The occlusion of mandibular gland and sublingual gland was induced by ligature in clinically normal dogs, and ultrasonograpic appearance, hematological changes and histological changes of the mandibular gland were observed daily during 6 days. The results were as follows. 1. The length, width, circumference and area of the mandibular gland in clinically normal dogs were 25.1 mm, 8.4 mm, 56.4 mm and 163.0 $\textrm{mm}^2$ in the left, and 23.4 mm, 8.0 mm, 53.3 mm and 141.6 $\textrm{mm}^2$in the right. 2. The length, width, circumference and area of the mandibular gland were gradually increased after ligature of the salivary duct, and revealed maximum values, as 33.4 mm, 10.9 mm, 73.0 mm and 287.2 $\textrm{mm}^2$, respectively, at 24 hours after ligature, and returned to normal size at 3 days after ligature. 3. The size of the opposite mandibular gland without ligature was also gradually increased until 24 hours, and returned to normal size at 3 days, similar to the changes of the mandibular gland with ligature. 4. There were no significant changes after ligature of the salivary duct in hematological findings. 5. In histopathological findings, the major of glandular alveoli was enlarged at 24 hours after ligature of the salivary duct, and neutrophils and monocytes were infiltrated at 6 days after ligature.

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3투사렌즈방식 LCD 프로젝션 TV의 엔진 냉각에 관한 연구 (A study on the cooling method for LCD projection TV with 3 projection lens)

  • 김철환;조여욱
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2004년도 추계학술대회
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    • pp.1253-1257
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    • 2004
  • We have developed new rear LCD Projection TV engine with 3 projection lens. It has high brightness and contrast ratio, however poor cooling conditions. If optical components close to light source, optical components are damaged on high temperature, especially the blue among RGB colors is weakest by heat In this study, a new enhanced cooling method of LCD projection TV with 3 lens is shown: the best suited design of duct and relations between LCD panel and polarizer lifetime with changed area of duct.

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종횡비가 큰 사각 덕트내 난류 유동의 대류 열전달 증진 기술에 대한 연구 (TURBULENCE HEAT TRANSFER ENHANCEMENT TECHNIQUE FOR SQUARE DUCT WITH HIGH ASPECT RATIO)

  • 이찬용;신승원;정하승;박승호
    • 한국전산유체공학회:학술대회논문집
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    • 한국전산유체공학회 2010년 춘계학술대회논문집
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    • pp.305-307
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    • 2010
  • In this study, we develop a method to achieve heat transfer enhancement inside a square duct with high aspect ratio without changing any inner structures. Especially, a method to lower the possible maximum temperature is suggested if constant heat flux is provided to single surface of square duct. Knowing the fact that heat transfer rate is inversely proportional to flow area, we proposed tapered channel concept which uses narrower gap toward the flow exit where the maximum temperature is expected. To maintain equivalent power consumption, inlet section has been enlarged. To verify the proposed concept, experimental tests have been performed.

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취출구를 가진 덕트의 공기분배장치 설계 (Design Of Air-Distribution System in a Duct)

  • 강형선;조병기;고영하
    • Journal of Advanced Marine Engineering and Technology
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    • 제31권8호
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    • pp.954-960
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    • 2007
  • The purpose of this paper is to obtain design method of air-distribution system. Air-distribution system is composed of blower, duct, diffusers and measuring equipment. The air-flow rate from each diffuser is not equal. The air-flow rate is calculated with the combined equations which are Bernoulli's equation, continuity equation and minor loss equations. Inlet condition and outlet condition are adapted in each duct system. Then square difference between function of maximum air-flow rate and minimum air-flow rate is used as an object function. Area of diffuser and velocity are established as constraints. To minimize the object function, the optimization method is used. After optimization the design variables are selected under satisfaction of constraints. The air-distribution system is calculated again with the result of optimized design variable. It is shown that the air-distribution system has the equal air-flow rate from diffusers.

연소조건 변화에 따른 LP가스버너의 배기특성 (Emission Characteristics of LP Gas Burner for the Variation of Combustion Conditions)

  • 이병곤;오택흠
    • 한국안전학회지
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    • 제16권4호
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    • pp.1-6
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    • 2001
  • An experimental study was carried out to investigate the emission characteristics of LP gas burner for the Practical combustion conditions including fm voltage, inlet area, gas Pressure, emission resistance, duct length and height. The result shows that CO is almost remains constant for the emission fan voltage, but significantly increases with the reduction rate of air inlet, up to 3000ppm at 50% of reduction rate. Also, the variation of gas pressure has no effect to CO of gas boiler due to its governor which controls gas pressure secondly, but it gives an rapid increase of CO for the gas range. The emission resistance test shows that CO is suddenly increased with the reduction rate of emission duct above 70% and main burner is stopped at 90%. The reverse wind test shows that CO is suddenly increased with the air velocity above 7m/s and main burner is stopped at 9m/s. The more horizontal length of emission duct is long and the vertical height is low, CO is infinitesimally increased.

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A Case of Cavitated Uterine Mass from Müllerian duct in a Mixed Breed Dog

  • Park, Chul-Ho;Son, Chang-Ho
    • 한국임상수의학회지
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    • 제35권6호
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    • pp.279-281
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    • 2018
  • This report describes a case of newly recognized congenital $M{\ddot{u}}llerian$ duct anomaly in a bitch. A fourteen-year-old, mixed breed bitch was presented with mild hematuria and mammary gland tumor. Complementary examinations were performed and abdominal ultrasonography revealed distended uterine horns and uterine tumor-like mass around the right ovarian area. Macroscopic examination showed the mass to be on the level of insertion of the right round ligament. The mass was cystic in nature, and had no communication with the uterine cavity. Histopathologically, the mass was identified as an accessory cavity lined by functional endometrium, which confirmed the diagnosis of accessory and cavitated uterine mass.

소아의 제장간막관 기형의 임상적 고찰 (Clinical Analysis of Vitelline Duct Anomalies in Children)

  • 김성집;정재희;송영택
    • Advances in pediatric surgery
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    • 제13권1호
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    • pp.37-44
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    • 2007
  • A vitelline duct (VD) anomaly is a relatively common congenital abnormality of the umbilical area. The anomalies include patent vitelline duct (PVD), cyst, fistula or sinus. The incidence is approximately 2% of the populations, but development of symptoms is rare. Recently, we experienced two cases; PVD accompanied by a small omphalocele and intestinal volvulus due to mesenteric band between Meckel's diverticulum and the mesentery. Thereafter,we evaluated the data of vitelline duct anomalies for 27 years. From 1980 to 2006, 18 cases of VD anomalies were reviewed based on the hospital records retrospectively. There were 15 boys and 3 girls and age ranged from 2 days to 15 years. Among the 18 cases, 15 cases were symptomatic and consisted of Meckel's diverticulum (10 cases), PVD (4 cases) and umbilical polyp (1 case). Three asymptomatic cases of Meckel's diverticulum were found incidentally were and were observed without resection. Ten cases of Meckel's diverticulum were presented with intestinal bleedings (4 cases), intestinal obstructions (5 cases) and perforation (1 case). Wedge resections and segmental resections of ileum were performed in 8 patients and 2 patients, respectively. Postoperative complications were adhesive ileus (1 case) and wound seroma (1 case). Small omphaloceles were accompanied in two of 4 PVD patients. There was 1 small omphalocele case which was accompanied by a prolapse of ileum. In summary, VD anomalies were more common in male and more than half of them were found in patients less than 1 year of age. PVD was diagnosed most frequently in neonates. Meckel's diverticulum presented with intestinal obstruction more frequently than bleeding.

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