• Title/Summary/Keyword: Duct area

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Comparison of Histopathological Changes on the Three Drugs of Carbon Tetrachloride, Dimethylnitrosamine, Thioacetamide, and Bile Duct Ligation used for Induction of Liver Fibrosis in Rat

  • Kim, Jung-Hun;Park, Mi-Jung;Kim, Yo-El;Kim, Jin-Yeong;Sin, Jin-Hee;Park, Su-Young;Jekal, Seung-Joo
    • Korean Journal of Clinical Laboratory Science
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    • v.43 no.4
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    • pp.194-204
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    • 2011
  • This study was carried out to compare the histopathological differences of liver lesions in carbon tetrachloride ($CCI_4$), dimethylnitrosamine (DMN), thioacetamide (TAA) and bile duct ligation (BDL)-induced rats. $CCl_4$, DMN and TAA were administered intraperitoneally and conducted bile duct ligation for 4 weeks to induce hepatic fibrosis. Indices of liver cell injury (steatosis, hydropic degeneration, bile duct hyperplasia, hemorrhage & hemosiderin deposition), the extent of liver fibrosis (fibrotic area) and the rate of regeneration (number of PCNA-positive cells) were investigated in each group. Liver tissues were stained with hematoxylin-eosin (HE), sirius red, prussian blue and immunostained with ${\alpha}$-smooth muscle actin (${\alpha}$-SMA), transforming growth factor-${\beta}1$ (TGF-${\beta}1$), proliferative cell nuclear antigen (PCNA), and quantified using a computerized image analysis system. Liver cell steatosis was significantly increased in $CCl_4$ and TAA groups, and hydropic degeneration and bile duct hyperplasia were significantly increased in TAA and BDL groups when compared with that in normal control, respectively. Fibrosis area was significantly increased in all four groups, especially in $CCl_4$ group. Correlation between ${\alpha}$-SMA and TGF-${\beta}1$ expressions in four groups was good. Hemorrhage area in liver parenchyma was significantly increased in DMN group only when compared with that in normal control, while hemosiderin deposition area was significantly increased in TAA and BDL groups as well as DMN group. The Number of PCNA-positive cells was significantly increased in all four groups, especially in TAA group. These results indicate that the duration and methods of hepatotoxic drug treatment are very important factors to make plans for animal experimentation on the induction of hepatic fibrogenesis in rats.

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Numerical Analysis of Collapse Behavior in Industrial Stack Explosive Demolition (산업용 연돌 발파해체에서 붕괴거동에 관한 수치해석적 연구)

  • Pu-Reun Jeon;Gyeong-Jo Min;Daisuke Fukuda;Hoon Park;Chul-Gi Suk;Tae-Hyeob Song;Kyong-Pil Jang;Sang-Ho Cho
    • Explosives and Blasting
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    • v.41 no.3
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    • pp.62-72
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    • 2023
  • The aging of plant structures due to industrialization in the 1970s has increased the demand for blast demolition. While blasting can reduce exposure to environmental pollution by shortening the demolition period, improper blasting design and construction plans pose significant safety risks. Thus, it is vital to consider optimal blasting demolition conditions and other factors through collapse behavior simulation. This study utilizes a 3-D combined finite-discrete element method (FDEM) code-based 3-D DFPA to simulate the collapse of a chimney structure in a thermal power plant in Seocheon, South Korea. The collapse behavior from the numerical simulation is compared to the actual structure collapse, and the numerical simulation result presents good agreement with the actual building demolition. Additionally, various numerical simulations have been conducted on the chimney models to analyze the impact of the duct size in the pre-weakening area. The no-duct, duct, and double-area duct models were compared in terms of crack pattern and history of Z-axis displacement. The findings show that the elapse-time for demolition decreases as the area of the duct increases, causing collapse to occur quickly by increasing the load-bearing area.

Experimental study of total pressure distortion in inlet S-ducts (INLET S-DUCT 내부흐름의 전압력 편차에 대한 실험 연구)

  • 김무도;정상영;김요섭
    • 제어로봇시스템학회:학술대회논문집
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    • 1987.10b
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    • pp.541-546
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    • 1987
  • An experimental study has been conducted to investigate the suction performance of a designed inlet. Total pressure distortion in the inlet S-duct was measured and the effect of lip thickness and throat area was analyzed. The volume flow rate of air into the turbojet engine was controlled to observe the effect of engine RPM to the total pressure distortion. The pressure data from 36 air tubes were obtained using scanivalve, pressure transducer, and visicoder system.

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Effects of Ligature of Mandibular Gland and Sublingual Gland on the Mandibular Gland in Dogs (개에서 턱밑샘관 및 혀밑샘관의 결찰이 턱밑샘에 미치는 영향)

  • 황학균;김명철
    • Journal of Veterinary Clinics
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    • v.16 no.1
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    • pp.57-64
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    • 1999
  • It was performed to evaulate the effects of occlusion of mandibular gland and sublingual gland on the mandibular gland in dogs. The occlusion of mandibular gland and sublingual gland was induced by ligature in clinically normal dogs, and ultrasonograpic appearance, hematological changes and histological changes of the mandibular gland were observed daily during 6 days. The results were as follows. 1. The length, width, circumference and area of the mandibular gland in clinically normal dogs were 25.1 mm, 8.4 mm, 56.4 mm and 163.0 $\textrm{mm}^2$ in the left, and 23.4 mm, 8.0 mm, 53.3 mm and 141.6 $\textrm{mm}^2$in the right. 2. The length, width, circumference and area of the mandibular gland were gradually increased after ligature of the salivary duct, and revealed maximum values, as 33.4 mm, 10.9 mm, 73.0 mm and 287.2 $\textrm{mm}^2$, respectively, at 24 hours after ligature, and returned to normal size at 3 days after ligature. 3. The size of the opposite mandibular gland without ligature was also gradually increased until 24 hours, and returned to normal size at 3 days, similar to the changes of the mandibular gland with ligature. 4. There were no significant changes after ligature of the salivary duct in hematological findings. 5. In histopathological findings, the major of glandular alveoli was enlarged at 24 hours after ligature of the salivary duct, and neutrophils and monocytes were infiltrated at 6 days after ligature.

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A study on the cooling method for LCD projection TV with 3 projection lens (3투사렌즈방식 LCD 프로젝션 TV의 엔진 냉각에 관한 연구)

  • Kim, Chul-Hwan;Joe, Yeo-Uk
    • Proceedings of the KSME Conference
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    • 2004.11a
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    • pp.1253-1257
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    • 2004
  • We have developed new rear LCD Projection TV engine with 3 projection lens. It has high brightness and contrast ratio, however poor cooling conditions. If optical components close to light source, optical components are damaged on high temperature, especially the blue among RGB colors is weakest by heat In this study, a new enhanced cooling method of LCD projection TV with 3 lens is shown: the best suited design of duct and relations between LCD panel and polarizer lifetime with changed area of duct.

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TURBULENCE HEAT TRANSFER ENHANCEMENT TECHNIQUE FOR SQUARE DUCT WITH HIGH ASPECT RATIO (종횡비가 큰 사각 덕트내 난류 유동의 대류 열전달 증진 기술에 대한 연구)

  • Lee, Chan-Yong;Shin, Seung-Won;Chung, Ha-Seung;Park, Seung-Ho
    • 한국전산유체공학회:학술대회논문집
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    • 2010.05a
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    • pp.305-307
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    • 2010
  • In this study, we develop a method to achieve heat transfer enhancement inside a square duct with high aspect ratio without changing any inner structures. Especially, a method to lower the possible maximum temperature is suggested if constant heat flux is provided to single surface of square duct. Knowing the fact that heat transfer rate is inversely proportional to flow area, we proposed tapered channel concept which uses narrower gap toward the flow exit where the maximum temperature is expected. To maintain equivalent power consumption, inlet section has been enlarged. To verify the proposed concept, experimental tests have been performed.

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Design Of Air-Distribution System in a Duct (취출구를 가진 덕트의 공기분배장치 설계)

  • Kang, Hyung-Seon;Cho, Byung-Ki;Koh, Young-Ha
    • Journal of Advanced Marine Engineering and Technology
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    • v.31 no.8
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    • pp.954-960
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    • 2007
  • The purpose of this paper is to obtain design method of air-distribution system. Air-distribution system is composed of blower, duct, diffusers and measuring equipment. The air-flow rate from each diffuser is not equal. The air-flow rate is calculated with the combined equations which are Bernoulli's equation, continuity equation and minor loss equations. Inlet condition and outlet condition are adapted in each duct system. Then square difference between function of maximum air-flow rate and minimum air-flow rate is used as an object function. Area of diffuser and velocity are established as constraints. To minimize the object function, the optimization method is used. After optimization the design variables are selected under satisfaction of constraints. The air-distribution system is calculated again with the result of optimized design variable. It is shown that the air-distribution system has the equal air-flow rate from diffusers.

Emission Characteristics of LP Gas Burner for the Variation of Combustion Conditions (연소조건 변화에 따른 LP가스버너의 배기특성)

  • 이병곤;오택흠
    • Journal of the Korean Society of Safety
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    • v.16 no.4
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    • pp.1-6
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    • 2001
  • An experimental study was carried out to investigate the emission characteristics of LP gas burner for the Practical combustion conditions including fm voltage, inlet area, gas Pressure, emission resistance, duct length and height. The result shows that CO is almost remains constant for the emission fan voltage, but significantly increases with the reduction rate of air inlet, up to 3000ppm at 50% of reduction rate. Also, the variation of gas pressure has no effect to CO of gas boiler due to its governor which controls gas pressure secondly, but it gives an rapid increase of CO for the gas range. The emission resistance test shows that CO is suddenly increased with the reduction rate of emission duct above 70% and main burner is stopped at 90%. The reverse wind test shows that CO is suddenly increased with the air velocity above 7m/s and main burner is stopped at 9m/s. The more horizontal length of emission duct is long and the vertical height is low, CO is infinitesimally increased.

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A Case of Cavitated Uterine Mass from Müllerian duct in a Mixed Breed Dog

  • Park, Chul-Ho;Son, Chang-Ho
    • Journal of Veterinary Clinics
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    • v.35 no.6
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    • pp.279-281
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    • 2018
  • This report describes a case of newly recognized congenital $M{\ddot{u}}llerian$ duct anomaly in a bitch. A fourteen-year-old, mixed breed bitch was presented with mild hematuria and mammary gland tumor. Complementary examinations were performed and abdominal ultrasonography revealed distended uterine horns and uterine tumor-like mass around the right ovarian area. Macroscopic examination showed the mass to be on the level of insertion of the right round ligament. The mass was cystic in nature, and had no communication with the uterine cavity. Histopathologically, the mass was identified as an accessory cavity lined by functional endometrium, which confirmed the diagnosis of accessory and cavitated uterine mass.

Clinical Analysis of Vitelline Duct Anomalies in Children (소아의 제장간막관 기형의 임상적 고찰)

  • Kim, Seong-Jip;Chung, Jae-Hee;Song, Young-Tack
    • Advances in pediatric surgery
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    • v.13 no.1
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    • pp.37-44
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    • 2007
  • A vitelline duct (VD) anomaly is a relatively common congenital abnormality of the umbilical area. The anomalies include patent vitelline duct (PVD), cyst, fistula or sinus. The incidence is approximately 2% of the populations, but development of symptoms is rare. Recently, we experienced two cases; PVD accompanied by a small omphalocele and intestinal volvulus due to mesenteric band between Meckel's diverticulum and the mesentery. Thereafter,we evaluated the data of vitelline duct anomalies for 27 years. From 1980 to 2006, 18 cases of VD anomalies were reviewed based on the hospital records retrospectively. There were 15 boys and 3 girls and age ranged from 2 days to 15 years. Among the 18 cases, 15 cases were symptomatic and consisted of Meckel's diverticulum (10 cases), PVD (4 cases) and umbilical polyp (1 case). Three asymptomatic cases of Meckel's diverticulum were found incidentally were and were observed without resection. Ten cases of Meckel's diverticulum were presented with intestinal bleedings (4 cases), intestinal obstructions (5 cases) and perforation (1 case). Wedge resections and segmental resections of ileum were performed in 8 patients and 2 patients, respectively. Postoperative complications were adhesive ileus (1 case) and wound seroma (1 case). Small omphaloceles were accompanied in two of 4 PVD patients. There was 1 small omphalocele case which was accompanied by a prolapse of ileum. In summary, VD anomalies were more common in male and more than half of them were found in patients less than 1 year of age. PVD was diagnosed most frequently in neonates. Meckel's diverticulum presented with intestinal obstruction more frequently than bleeding.

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