• Journal of Digestive Cancer Research
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• 제11권2호
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• pp.104-107
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• 2023

The Ministry of Health and Welfare of Korea has implemented various social security programs to ensure a basic standard of living and raise overall quality of life for all citizens. The Korean social security system provides social insurance, public assistance, and social welfare services. To achieve adequate drug benefits, the Drug Management Department of Health Insurance Review and Assessment Service (HIRA) implement drug management duties including drug listing, upper price limit setting, scope of benefits, and post-factum management. When a manufacturer or an importer wants to apply for National Health Insurance (NHI) coverage of the drug that has obtained safety and efficacy approval, the pharmaceutical benefit assessment committee of HIRA evaluates the drug's clinical efficacy and cost-effectiveness to determine whether or not to include the drug into the benefit package. The benefit standards for a listed drug (ingredient) are set either for the whole permitted range or a part of range with conditions. To increase the coverage rate for new drugs, the listed drugs are regularly reviewed for their value. The status of listed drugs can be adjusted or eliminated from the benefit package if the clinical efficacy turns out to be insignificant. Therefore, through these pharmaceutical management procedures, high-quality drugs are provided at reasonable prices, which save healthcare expenditure by price determination and selective coverage in consideration of economic evaluation.

• 한국전기전자재료학회논문지
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• 제31권2호
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• pp.122-127
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• 2018

In an attempt to estimate the life projection of LED packages, IESNA published a paper regarding an LED package measurement test method in 2008, and a life projection technical document in 2011, to be used for LED life estimation. IESNA's publications regarding LED package measurement methods were functional, but they were not internationally standardized before 2017. In order to develop a standardized method, the International Standard chose to use the LM-80 as a measurement method for LED life projection in their publication in 2017. Many projection methods have been discussed by the IEC Technical Committee 34 working group, including the method using an exponential function, which reflects lumen degradation characteristics well. This study is designed to explore alternative LED package life estimation methods using an exponential function with statistical analysis, other than the one suggested by the International Standard.

• 환경위생공학
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• 제20권2호
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• pp.39-46
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• 2005

This study was Performed to survey and evaluate the contents of Plasticizers such as DEP(diethyl phthalate), DPrP(di-n-Phthalate), DBP(di-n-butyl Phthalate), DPP(di-n-pentyl Phthalate), DCHP(dicyclohexyl phthalate), BBP (butylbenzyl phthalate), DEHP(di-(2-ethylhexyl) phthalate) and DEHA(di-(2-ethylheryl) adipate), which are suspected as endocrine disruptors, in food and drug PVC packaging. Tested samples were 5 food wraps, 35 food containers, 40 food and drug packages(type of tablet and capsule) in Gyeonggi-Do area. The contents of DEHA in wrap were 188.9g/kg, 203.1g/kg, 238.4g/kg, 290.9g/kg and 308.3g/kg, respectively, while the other plasticizers were not detected. DEHP was used in 4 samples of food containers and DEHP contents were 4.7g/kg, 30.7g/kg, 35.8g/kg and 53.4g/kg, respectively. In food and drug packaging materials(type of tablet and capsule), the plasticizers were not detected.

• 대한예방한의학회지
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• 제17권3호
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• pp.143-153
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• 2013

Objective : This study was done to define the treatment protocol of Traditional Korean Medicine for persistent allergic rhinitis, which might be necessary for conducting PRCT study. Methods : Data were collected by questionnaire from Korean Medicine doctors participated in the Conference of The Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology Society in October 2012. We investigated their treatment procedures for persistent allergic rhinitis in ordinary clinical settings. Their treatment patterns including annual treatment period, frequencies and treatment times were also investigated. Finally, we combined the national insurance covered or out-of-pocket treatments as treatment packages according to the response rates of each contents, and displayed them as treatment protocols for PRCT study. Results : 50 Korean medicine doctors described the informed consent and questionnaire. Response rates of each treatment procedure were listed in Table 2 to Table 5. Treatment periods, frequencies and treatment time of each visit were listed in Table 6. Finally, treatment packages which would be defined for PRCT were listed in Table 7 as treatment package 1(response rates were over 50%), package 2(response rates were over 25%), package 3(response rates were over10%). Conclusion : These results provide the rational background and preliminary sources of defining treatment packages for developing PRCT protocols.

• 약학회지
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• 제56권5호
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• pp.333-345
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• 2012

A product labelling is one of key tools in ensuring that a patient uses drugs safely and effectively in self-care without professional support. This study aimed to explore the readability and comprehensibility of the information contained on two package inserts of medicines. Two package inserts were tested with first year college students. Fifty-one potential consumers underlined words they could not understand and answered 10 scenario questions. Any differences among groups with different characteristics were statistically tested. Secondly, the readability of two package inserts was assessed with comparison to the level of the 6th grade Korean textbooks. As results, more than 80% of participants properly replied to straightforward questions concerning indication, dosage, duplication, use in pregnancy and contraindication, and 73% about formulation. Less than half answered correctly in multiple choice questions about pediatric use (41%) and side effects (35%). Little discrepancy was observed in the comprehensibility between participants' characteristics. Drug inserts contained about 20% more professional-level words than 6th grade textbooks. In conclusion, Korean consumers may face challenges to understand drug information due to professional terminology and outdated expressions in the current package inserts. To secure safe and effective use of over-the-counter agents, greater efforts should be made to develop more consumer friendly labels. In the other hand, educational supports are required to prepare consumers in a proper level of knowledge for the safe use of drugs.

• 디자인융복합연구
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• 제15권4호
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• pp.17-29
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• 2016

편의점에서 판매되고 있는 안전상비의약품은 약사법에 따라 의약품의 용기나 포장 또는 첨부문서 기재사항을 정함으로써 의약품의 투약과실을 예방하고 알기 쉽고 정확한 의약품 정보를 제공하고 있다. 하지만 제한된 포장면적으로 인해 정보의 가독성이 떨어져 소비자들이 구매하기에는 어려움이 따른다. 본 연구에서 알약 형태인 8개 품목을 중심으로 규정에 따른 포장 분석을 실시하고 외국인 10명과 내국인 20명의 소비자들을 대상으로 설문 및 심층 인터뷰를 통하여 사용자 의식 조사를 진행하였다. 그 결과, 가장 많이 구매하는 품목은 해열제라는 것과 구매 전 의약품 포장에서 찾는 정보는 효능·효과, 용량·용법, 사용상의 주의사항의 순이라는 것을 알 수 있었다. 포장정보에 대한 이해도는 내국인의 경우 이해에 큰 문제가 없었던 반면, 포장의 모든 표기가 한글로만 되어있어 외국인의 40%이상에서 이해하지 못한다고 응답하였다. 디자인 개선안으로 픽토그램과 영어표기를 적용해 효능·효과와 용량·용법, 연령 총 세 가지로 각 포장의 윗면 오른쪽에 위치하여 한 눈에 어떤 약인지 구별할 수 있게 하자는 제안하고자 한다. 이를 통해 소비자들이 구매함에 있어 이해도와 편의성을 높일 수 있길 기대한다.

• 한국임상약학회지
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• 제23권4호
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• pp.334-343
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• 2013

Purpose: This study aims to investigate consumers' demand of and perspective on drug information domestically available and uncover hurdles that they faced while utilizing information. Methods: We conducted a survey of 101 consumers, face-to-face after obtaining informed consent. Chi-squared, or Fisher's exact tests, and multivariate logistic models were used to investigate the association between participants' perceptions and characteristics. Results: As results, participants showed the highest demand for "Adverse effects >90%"; "Drug interactions/Dosage/Drug-food interactions/Indication >80%", and utilized package inserts (52%), doctors (41%) and pharmacists (36%) most often as information sources. Generally, the most common difficulty consumers suffered with was that "it is hard to understand (51%)". With public sources of drug information, sixty one percent of participants were "unaware of the provision of information", resulting in strikingly low usage rates (5~11%). Subgroup analyses indicated that the older (${\geq}50$ years) and the disadvantaged might have been placed in the blind spot of information mostly developed online (p<0.05).Conclusion: In conclusion, public sources of drug information that have been developed online might fail to meet consumers' demand. Greater efforts should be made to balance the development of the information sources between online and offline, and to increase accessibility of the established information sources.

• 한국포장학회지
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• 제23권3호
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• pp.173-181
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• 2017

본 연구에서는 한국의 가공식품 포장 특징(재질, 형태 등)을 분석하기 위해 다소비 식품에서 가공식품만을 대상으로 하여 품목별 소매점 매출액 순위에 따라 구성하였고, 이를 품목별 포장 형태, 품목별 포장 재질, 포장 형태별 포장 재질로 나누어 분석하였다. 또한, 품목별, 포장 형태별, 포장 재질별 접촉 비율과 두께를 측정하고 분석하였다. 국내 유통 중인 가공식품의 포장 재질별 사용 실태 조사 결과, 폴리에틸렌(PE, 43.61%), 폴리프로필렌(PP, 17.75%), 폴리에틸렌 테레프탈레이트(PET, 12.05%), 알루미늄(9.08%) 순으로 사용 빈도가 높아, 합성수지제를 가장 많이 사용하나 전반적으로 다양한 포장 재질을 사용하고 있는 것으로 조사되었다. 가공식품의 포장 형태별 사용 실태를 조사한 결과, EU 기준에 따른 포장 형태 총 21가지로 분류되었고, 가장 많이 쓰이는 포장 형태는 유연 포장재/봉투/파우치(38.96%)로 조사되었다. 본 연구는 가공식품 포장 재질, 포장 형태, 포장재 두께, 포장재와 식품의 접촉 비율 등의 구체적이고 방대한 양의 정보를 정리하여 국내의 가공식품 포장 현황을 반영한 조사로써, 향후 국내 식품포장 현황 분석 연구에 있어 기초 자료를 제공하는 데에 도움이 될 것으로 기대된다.

• 한국임상약학회지
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• 제32권3호
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• pp.226-237
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• 2022

Background: Monoclonal antibodies for the treatment of patients with different types of cancer, such as cetuximab, have been widely used for the past 10 years in oncology. Although drug information package insert contains some representative adverse events which were observed in the clinical trials for drug approval, the overall adverse event patterns on the real-world cetuximab use were less investigated. Also, there have been no published papers that deal with the full spectrums of adverse drug events of cetuximab using national-wide drug safety surveillance systems. Methods: In this study, we detected new adverse event signals of cetuximab in the Korea Adverse Event Reporting System (KAERS) by utilizing proportional reporting ratios, reporting odds ratios, and information components indices. Results: The KAERS database included 869,819 spontaneous adverse event reports, among which 2,116 reports contained cetuximab. We compared the labels of cetuximab among the United States, European Union, Australia, Japan, and Korea to compare the current labeling information and newly detected signals of our study. Some of the signals including hyperkeratosis, tenesmus, folliculitis, esophagitis, neuralgia, disseminated intravascular coagulopathy, and skin/throat tightness were not labeled in the five countries. Conclusion: We identified new signals that were not known at the time of market approval.

• 한국가정과교육학회지
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• 제10권2호
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• pp.145-161
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• 1998

The purpose of this study was to survey the actual condition of the Middle School Students on a Drug. In this study, 500 middle school students in Seoul response to a questionnaire which is composed to analyse two categories, i.e. general facts, the actual condition of drug use (the frequency of drug use, the degree of perception on drugs, the people using a drug surrounding the degree of purchase on drugs). And the students are classified by satisfactory degree on their home backgrounds, satisfactory degree on their school life, and school record. The data is analysed by means of frequency, percentage, chi-square test and Pearson's correlation using the $SPSS-PC^+$ package program. The results of this study were as follow : The frequency of drug use except a alcohol and the degree of perception on a drug among female students are higher than among male. The female students are more permissive on the drug use and they are also tend to think more easily the purchase of a drug. The frequency of drug use and the degree of perception on drugs are higher in the group of the lower satisfactory degree on their home background. Especially, there are many people using drugs surrounding the students in the lower group. The frequency of drug use and the degree of perception on drugs are higher in the group that has the lower satisfactory degree on school life. The students in the group having low school record have more dangerous thought about the use of drugs than the students of high record. The degree of perception on a drug is higher in a higher group, and the students in a higher group also think more easily the purchase of drugs. The percentage of students using drugs are not high, but the high percentage of students are interested in the drugs and they have permissive attitudes on drugs. Thus, the preventive education for drug abuse must be done rapidly.