• Title/Summary/Keyword: Drug contents

Search Result 664, Processing Time 0.026 seconds

Fabrication and Characterization of Flurbiprofen loaded Chitosan Beads for Periodontal Regeneration (치주조직 재생용 플루르비프로펜 함유 키토산 비드의 제조 및 용출특성)

  • Rhee, Su-Jin;Park, Yoon-Jeong;Lee, Seung-Jin;Chung, Chong-Pyoung
    • Journal of Pharmaceutical Investigation
    • /
    • v.27 no.1
    • /
    • pp.71-77
    • /
    • 1997
  • With the aim of improving periodontal regeneration efficacy, as a biodegradable local drug delivery device, drug releasing chitosan beads were prepared. Chitosan beads were prepared through the formation of intermolecular or intramolecular ionic interaction bewteen chitosan and sodium tripolyphosphate and were loaded with flurbiprofen. The mean diameter of the beads was $250\;{\mu}m$. Drug loading efficiency was improved by regulating the pH of tripolyphosphate solution. The drug release kinetics mainly depended upon the hydrophobic properties of the flurbiprofen, that is, the release of flurbiprofen showed initial burst with rapid release for the first day followed by a levelling off of the release rate. However, the release rate could be controlled by the formulation factor including the pH, concentration of the tripolyphosphate solution, gelation time, drug contents. From these results, flurbiprofen loaded chitosan beads were anticipated as biodegradable local drug delivery devices for periodontal regeneneration.

  • PDF

Comparison of Colorimetric Methods for the Determination of Flavonoid in Propolis Extract Products (프로폴리스추출물 제품의 플라보노이드 함량분석을 위한 비색법의 비교)

  • Kim, Eun-Jeong;Lee, Hwa-Jung;Kim, Hye-Jeong;Nam, Hye-Seon;Lee, Mi-Keong;Kim, Hae-Young;Lee, Jin-Ha;Kang, Yun-Sook;Lee, Jong-Ok;Kim, Hee-Yun
    • Korean Journal of Food Science and Technology
    • /
    • v.37 no.6
    • /
    • pp.918-921
    • /
    • 2005
  • Quantitative analysis of flavonoids in commercial propolis extract products were compared by three colorimetric methods; aluminum chloride method, dinitrophenylhydrazine method and aluminum nitrate method, Aluminum nitrate method in Korea Health Supplement Food Code was proved to be specific only for flavones and flavonols same as aluminum chloride method, while dinitrophenylhydrazine method was specific for flavanones and dihydroflavonols. Therefore, the sum of flavonoid contents determined by 2,4-Dinitrophenylhydrazine method and aluminum nitrate method may represent the real content of total flavonoids. As for the 25 commercial propolis extract products examined, the contents of flavonoid varied from 2.15% to 9.53% except for one product.

A Study On Subjective Experience Of Drug Abuse Adolescent (약물남용 청소년의 주관적 경험에 관한 연구)

  • 김미희
    • Journal of Korean Academy of Nursing
    • /
    • v.30 no.1
    • /
    • pp.7-17
    • /
    • 2000
  • The purpose of this study is to affect health improvement of adolescent, to understand behavioral causes follow adolescent's drug abuse, to understand recovery and rehabilitaton process of adolescent drug abuser. The data are collected through open questionnaire and interview of 25 adolescents from the experienced drug abuse 16 students(male 8, female 8) in two vocational high schools and admissing adolescents 9 person in Alcohol-Drug Addiction Care Centre in Seoul from June 28th to August 31st, 1994. The collected data are arranged and explained through categorizing method stated contents about motives, causes, experiences and effected behaviors for using the drugs of drug abuser adolescents. DRUG USING MOTIVATION They are almost first son and daughter in their family. In their conversation person, male converses to their mother well, but female does not converse to their parents include family. Both groups respond positively to companionship and attitude to other, but negatively to self-confidence and actualizing attitude. They hope always peace of family and want to do their best for their life. In school group, hard and difficult things are school life and family problems, also using the drugs for resolving the them. About drug using behaviors, male responds to bad habbit and shamfull, but female is unconcerned with drug using attitude. The first background of drug using, male gets to use because of curiosity and to be induced from friends or seniors, but female gets to use for feminine beauty(thin body) and escape from reality. Used the drugs, male uses frequently Bond, Butane-Gas among inhalation materials and also marijuana, but female uses various diuretics. The times of drug using, both groups repond to use during the chaging of emotion or filling with stress. The place of drug using, both groups take drugs in vacant houses or in the mountain. The frequency of drug using, they use almost once in a day and they use mostly alone or drug user in friends. Experienced mental changing after drug using, which is fantasy, ecstasy, anxiety and suicidal feeling, and experienced physical changing after drug using, which is elevating sense, headach, abdominal pain, dyspnea and chaging of skin colour and reddish. They coincide with inconvenience feeling due to drug using. RECOVERY AND REHABILITATION PROCESS OF DRUG USING ADOLESCENTS The reason for reforming drug using behavior and attitude, both groups respond to reforming for oneself and social life. The difficult things during the stop to using drugs, all of them responed to family problems, friends problems and temptation and impulse. As for stop to using drug, they need good advise, understandable attitude and family love. But they do not need to be stigmatized, scolding, over protect and ridicule of friends. Also they entreat continuous understanding, advise, concern and the method for resolving stress. For the friends to want to use the drug, they will talk about the stories of their personal experiences and for the friends to stop to using the drug, they will consider for them how to stop. From the theses results, drug users understand personal problems due to drug using, and consider about why to stop and how to stop. Also drug users need to resolve the family problems, personal problems, stress and temptations or impulses. Accordingly this paper suggests that drug users in adolescents need understandable and acceptable atitudes, loving and tenderness, continuous advice and concern, and hopes for life.

  • PDF

Monitoring Heavy Metals in Meat and Meat Products (식육 및 그 가공품의 중금속 모니터링)

  • Hwang, Tae-Ik;Ahn, Tae-Hyun;Kim, Eun-Jung;Lee, Jung-Ah;Kang, Myoung-Hee;Jang, Young-Mi;Kim, Mee-Hye
    • Korean Journal of Food Science and Technology
    • /
    • v.43 no.5
    • /
    • pp.525-531
    • /
    • 2011
  • This study was conducted to examine the contents of lead (Pb), cadmium (Cd), arsenic (As), and mercury (Hg) in meat and meat products in Korea. The contents of Pb, Cd, As, and Hg in 466 samples of beef, pork, chicken, duck, ham, and sausage were measured using inductively coupled plasma mass spectrometry or a mercury analyzer. Wet ashing and microwave method were compared, and the recovery and reproducibility of the microwave method were better than those of wet ashing for meat and meat products. The recovery of the microwave method was 98.1% for Pb, 104.6% for Cd, and 103.4% for As, respectively. The best result was obtained through digestion using an acid mixture ($HNO_3$/$H_2O_2$, 6:2). Hg content was measured using a mercury analyzer. As a result, the contents of Hg and Cd in samples were lower than those of Pb and As. The average contents of Pb were 0.009 mg/kg in beef, 0.010 mg/kg in pork, 0.006 mg/kg in chicken, 0.007 mg/kg in duck, 0.005 mg/kg in ham, and 0.009 mg/kg in sausage. The average Cd contents were 0.0004 mg/kg in beef, 0.0004 mg/kg in pork, 0.0005 mg/kg in chicken, 0.0012 mg/kg in duck, 0.0015 mg/kg in ham, and 0.0019 mg/kg in sausage. The average As contents were 0.016 mg/kg in beef, 0.004 mg/kg in pork, 0.021 mg/kg in chicken, 0.010 mg/kg in duck, 0.014 mg/kg in ham, and 0.018 mg/kg in sausage. The average Hg contents were 0.713 ${\mu}g/kg$ in beef, 0.902 ${\mu}g/kg$ in pork, 0.710 ${\mu}g/kg$ in chicken, 0.796 ${\mu}g/kg$ in duck, 1.141 ${\mu}g/kg$ in ham, and 1.052 ${\mu}g/kg$ in sausage. Based on the results of the National Health and Nutrition Survey 2005, the levels of dietary exposure to heavy metal contaminants in meat and meat products were compared with the provisional tolerable weekly intake(PTWI) established by the Joint FAO/WHO Expert Committee on Food Additives. The average dietary exposure of the general population from meat and meat products was 0.03-0.2% of PTWI for Pb, Cd, As, and Hg, which indicates a safe level for public health at present.

Monitoring of Total Sugar Contents in Processed Foods and Noncommercial Foodservice Foods (국내 유통 가공식품과 단체급식 메뉴의 당 함량 실태조사)

  • Choi, Mi-Hee;Kwon, Kwang-Il;Kim, Jee-Young;Lee, Jee-Sun;Kim, Jong-Wook;Park, Hye-Kyung;Kim, Myung-Chul;Kim, Gun-Hee
    • Korean Journal of Food Science and Technology
    • /
    • v.40 no.3
    • /
    • pp.337-342
    • /
    • 2008
  • In this study, HPLC was used to determine the total sugar contents of processed foods as well as main and side dishes that were acquired from noncommercial foodservices. The total sugar content was identified as the total amount of both mono- and di-saccharides according to the nutritional information standard defined by the Korea Food and Drug Administration. The results for the processed foods were as follows: $25.3{\pm}9.5%$ for biscuits, $11.7{\pm}10.6%$ for snacks, $29.9{\pm}17.7%$ for chocolate, $35.5{\pm}9.3%$ for processed chocolate products, $11.0{\pm}2.7%$ for fruit juice, $10.0{\pm}3.6%$ for carbonated beverages, $23.0{\pm}3.2%$ for ice cream, $24.5{\pm}3.2%$ for ice milk, and $11.4{\pm}2.6%$ for stirred yogurt. Overall, candy items had relatively higher total sugar contents ($71.1{\pm}19.3%$ ) than any other items. Foods in the school zone had $52.3{\pm}24.4%$ total sugars. The noncommercial foodservice foods were classified into 5 main dish categories and 12 side dish categories. The total sugar contents of the main dishes were $2.6{\pm}1.9%$ for cooked rice with seasoning, and $4.7{\pm}0.1%$ for spaghetti. Among the side dishes, hard boiled foods and stir-fried foods contained the highest amounts of sugar, which were dependent on the main ingredients in the foods. Other side dishes with high sugar contents included seasoned vegetables/dried fish/seaweed ($5.5{\pm}5.3%$), salads ($5.6{\pm}3.1%$), and kimchies ($5.7{\pm}4.1%$). The total sugar contents of the side dishes ranged widely, and were significantly different according to main ingredients, cooking method, and amount of spice.

The Study on Heavy Metal Contents in Various Foods (여러 가지 식품 중 중금속 함량에 관한 연구)

  • Kim, Mee-Hye;Kim, Jung-Soo;Sho, You-Sub;Chung, So-Young;Lee, Jong-Ok
    • Korean Journal of Food Science and Technology
    • /
    • v.35 no.4
    • /
    • pp.561-567
    • /
    • 2003
  • This study was conducted to estimate the heavy metal contents in various foods (n=696). The contents of lead (Pb), cadmium (Cd) and tin (Sn) were determined using and ICP (inductively coupled plasma spectrometer). The content of mercury (Hg) was determined using a mercury analyzer. The values of heavy metals in canned foods were as follows [minimum-maximum (mean), mg/kg]; Pb 0.001${\sim}$0.36 (0.10), Cd 0.001${\sim}$0.10 (0.04), Sn 0.01${\sim}$24.75 (2.60). The mean values of Pb and Cd in animal foods were 0.40 mg/kg and 0.03 mg/kg. Also, the mean values of heavy metals in vegetables and potatoes were 0.03 mg/kg for Pb, 0.02 mg/kg for Cd, 0.001 mg/kg for Hg, respectively. The mean values of Hg in fishes and canned fishes were 0.08 mg/kg and 0.04 mg/kg. Our results showed that heavy metal contents in various foods available on markets were similar to those reported in other countries.

Illegal and Harmful Information Detection Technique Using Combination of Search Words (단어 조합 검색을 이용한 불법·유해정보 탐지 기법)

  • Han, Byeong Woo;Yoon, Ji Won
    • Journal of the Korea Institute of Information Security & Cryptology
    • /
    • v.26 no.2
    • /
    • pp.397-404
    • /
    • 2016
  • Illegal and harmful contents on the Internet has been an issue and been increased in Korea. They are often posted on the billboard and website of small enterprise and government office. Those illegal and harmful contents can relate to crime and suspicious activity, so, we need a detection system. However, to date the detection itself has been conducted manually by a person. In this paper, we develop an automated URL detection scheme for detecting a drug trafficking by using Google. This system works by analyzing the frequently used keywords in a drug trafficking and generate a keyword dictionary to store words for future search. The suspected drug trafficking URL are automatically collected based on the keyword dictionary by using Google search engine. The suspicious URL can be detected by classifying and numbering each domain from the collection of the suspected URL. This proposed automated URL detection can be an effective solution for detecting a drug trafficking, also reducing time and effort consumed by human-based URL detection.

Examination of Validity of Motivation Activation Tendency as a Target Group in Delivering Anti-drug Advertisements (마약퇴치 광고의 표적 집단 활용을 위한 동기 활성화의 타당도 조사)

  • Lee, Seungjo
    • The Journal of the Korea Contents Association
    • /
    • v.17 no.8
    • /
    • pp.301-311
    • /
    • 2017
  • The current study investigated whether individual variation in motivational activation would predict the drug-use and interacts with discrete emotions to influence the responses to anti-drug advertisements. Motivational activation tendency indicates an individual's level to approach life-sustaining elements and defend life-threatening stimuli. Discrete emotion represents joy, sadness, and fear elicited by the advertisements. The experiment proceeded using both self-reports and physiological responses with 80 subjects. Results showed that approach motivation activation can be a target for anti-drug advertisements and in order to target individuals higher in approach activation, it is necessary to use the appeal type to elicit positive emotions such as joy.