• Journal of Ginseng Research
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• 제43권2호
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• pp.179-185
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• 2019

Background: Oxidative stress induces the production of reactive oxygen species (ROS), which play important causative roles in various pathological conditions. Black ginseng (BG), a type of steam-processed ginseng, has drawn significant attention due to its biological activity, and is more potent than white ginseng (WG) or red ginseng (RG). Methods: We evaluated the protective effects of BG extract (BGE) against oxidative stress-induced cellular damage, in comparison with WG extract (WGE) and RG extract (RGE) in a cell culture model. Ethanolic extracts of WG, RG, and BG were used to evaluate ginsenoside profiles, total polyphenols, flavonoid contents, and antioxidant activity. Using AML-12 cells treated with $H_2O_2$, the protective effects of WGE, RGE, and BGE on cellular redox status, DNA, protein, lipid damage, and apoptosis levels were investigated. Results: BGE exhibited significantly enhanced antioxidant potential, as well as total flavonoid and polyphenol contents. ATP levels were significantly higher in BGE-treated cells than in control; ROS generation and glutathione disulfide levels were lower but glutathione (GSH) and NADPH levels were higher in BGE-treated cells than in other groups. Pretreatment with BGE inhibited apoptosis and therefore protected cells from oxidative stress-induced cellular damage, probably through ROS scavenging. Conclusion: Collectively, our results demonstrate that BGE protects AML-12 cells from oxidative stress-induced cellular damages more effectively than WGE or RGE, through ROS scavenging, maintenance of redox status, and activation of the antioxidant defense system.

• 대한조선학회논문집
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• 제58권2호
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• pp.58-65
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• 2021

In order to study the self-propulsion test and analysis techniques for the submerged body in Large Cavitation Tunnel (LCT). DARPA Suboff, a submarine model publicly available was manufactured. The resistance results of DARPA Suboff was acquired from the LCT tests and compared with those of DTRC. After the wall blockage correction, the resistance results of LCT were in good agreement with those of DTRC. On the basis of the resistance results of LCT, the self-propulsion tests were conducted in LCT. The test objective was to get the full-scale propeller operating conditions for the propeller cavitation and noise tests. The test results of DARPA Suboff were analyzed in a way similar to the analysis techniques of those of the Towing Tank (TT). Another submerged body, for which self-propulsion tests were conducted in TT, was selected for results verification. The results of LCT were in good agreement with those of TT. On the basis of the present study, it is thought that the operating conditions for the full-scale submerged body can be drawn through LCT tests.

• Imaging Science in Dentistry
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• 제50권4호
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• pp.323-330
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• 2020

Purpose: The mastoid region is ideal for studying sexual dimorphism due to its anatomical position at the base of the skull. This study aimed to determine sex in the Iranian population based on measurements of the mastoid process using different data mining algorithms. Materials and Methods: This retrospective study was conducted on 190 3-dimensional cone-beam computed tomographic (CBCT) images of 105 women and 85 men between the ages of 18 and 70 years. On each CBCT scan, the following 9 landmarks were measured: the distance between the porion and the mastoidale; the mastoid length, height, and width; the distance between the mastoidale and the mastoid incision; the intermastoid distance (IMD); the distance between the lowest point of the mastoid triangle and the most prominent convex surface of the mastoid (MF); the distance between the most prominent convex mastoid point (IMSLD); and the intersecting angle drawn from the most prominent right and left mastoid point (MMCA). Several predictive models were constructed and their accuracy was compared using cross-validation. Results: The results of the t-test revealed a statistically significant difference between the sexes in all variables except MF and MMCA. The random forest model, with an accuracy of 97.0%, had the best performance in predicting sex. The IMSLD and IMD made the largest contributions to predicting sex, while the MMCA variable had the least significant role. Conclusion: These results show the possibility of developing an accurate tool using data mining algorithms for sex determination in the forensic framework.

• 산업노동연구
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• 제23권2호
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• pp.141-167
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• 2017

본 연구는 작업장혁신 프로그램들의 고용효과에 관한 실증분석이다. 본 연구의 이론 모형과 가설은 혁신 일반의 고용효과에 관한 기존의 연구결과들을 발전시켜서 개발하였다. 사용 자료는 노사발전재단의 "일터혁신지수" 2013-14년 자료이다. 사용 자료는 횡단면 자료이고 통계모형은 OLS 모형이다. 본 회귀모형의 종속변수는 고용증가율이고 주된 독립변수는 작업장혁신 지수이다. 작업장혁신 지수는 TQM/6시그마, 제안제도, 다기능훈련 등을 합성하여 작성하였는데, 그 관행들의 도입 여부와 활용 정도(표준화값) 등 2 가지로 된 측정치들로 구성하였다. 분석 결과 작업장혁신 프로그램들의 도입 여부는 고용증가율에 통계적으로 유의한 영향을 미치지 못하고, 작업장혁신 프로그램들의 활용 정도는 고용증가율에 약하게 통계적으로 유의한 양(+)의 영향을 미치고 있었다. 이상의 분석 결과들은 작업장혁신의 도입이 고용에 통계적으로 유의한 영향을 미치지 못하고 있음을 말해주고 있는데, 그것의 활용도를 높일 경우에는 약한 수준에서나 고용에 긍정적인 영향을 미칠 가능성이 있음을 시사하고 있다. 그 밖에 정부 지원의 조직혁신 컨설팅을 받은 사업체(+), 임금수준(-), 1인당 훈련시간(+), 전년도 근로자수(-) 등이 고용증가율에 통계적으로 유의한 영향을 미치고 있다. 마지막으로 본 연구의 실증결과들을 요약하고, 연구의 한계와 향후 연구의 방향을 논의하였다.

• 정보보호학회논문지
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• 제22권1호
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• pp.155-167
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• 2012

클라우드 컴퓨팅 서비스는 이용자 요구에 실시간으로 유연하게 컴퓨팅 자원을 제공하고 사용량만큼 과금하는 고효율의 차세대 IT 서비스이다. 그러나 이용자는 데이터를 '위탁'하고, 인프라, 플랫폼, 어플리케이션 서비스를 '제공'받는 '위탁/제공'의 서비스 구조와 적용기술, 자원공유, 데이터센터 위치 등으로부터 비롯된 많은 위협에 직면해 있다. 클라우드 서비스 도입의 가장 큰 걸림돌로 작용하는 보안과 신뢰성을 담보하기 위해서는 객관적인 평가 기준이 필요하다. 지금까지 정보보호관리체계는 조직의 보안관리 및 IT 운영의 보안 지표로 활용되어 왔다. 그러나 클라우드 컴퓨팅 서비스는 기존의 조직 내 IT 환경과는 다른 관점의 보안관리와 평가기준이 필요하다. 본 논문에서는 클라우드 특성에 맞는 정보보호관리체계를 설계하기 위하여 클라우드 서비스의 핵심요소를 위협관리영역으로부터 도출하고 기본적인 보안관리가 누락되지 않도록 기존 정보보호관리체계의 모든 통제영역을 포함하고 있다. 또 온라인 셀프환경에 따른 서비스 이용을 지원하고 서비스 계약, 제공자 사업현황을 포함하는 서비스 보안관리를 추가하여 설계한다.

• Steel and Composite Structures
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• 제38권2호
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• pp.223-239
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• 2021

This paper presents the analytical modeling and finite element (FE) analysis, using ABAQUS software, of the new types of steel reinforced lightweight aggregate concrete (SRLAC) columns with cross-shaped (+shaped and X-shaped) steel section, using proposed three analytical and two FE models in total. The stress-strain material models for different components in the columns, including the confined zones of the lightweight aggregate concrete (LWAC) using three and four concrete zones divisions approaches and with and without taking into account the stirrups reaction effect, are established first. The analytical models for determining the axial load-deformation behavior of the SRLAC columns are drawn based on the materials models. The analytical and FE models' results are compared with previously reported test results of the axially loaded SRLAC columns. The proposed analytical and FE models accurately predict the axial behavior and capacities of the new types of SRLAC columns with acceptable agreements for the load-displacement curves. The LWAC strength, steel section ratio, and steel section configuration affect the contact stress between the concrete and steel sections. The average ratios of the ultimate test load to the three analytical models and FEA model loads, Put /Pa1, Put /Pa2, Put /Pa3, and Put /PFE1, for the tested specimens are 0.96, 1.004, 1.016, and 1.019, respectively. Finally, the analytical parametric studies are also studied, in terms of the effects of confinement, LWAC strength, steel section ratio, and the reinforcement ratio on the axial capacity of the SRLAC column. When concrete strength, confinements, area of steel sections, or reinforcement bars ratio increased, the axial capacities increased.

• 대한예방한의학회지
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• 제26권3호
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• pp.1-16
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• 2022

Backgrounds : Doctor of Osteopathy (D.O.) in the United States have drawn attention as one of the future models of Korean Medicine doctors in Korea in that they have their own fields of care and therapies that distinguish them from medical doctor (M.D.), but are also able to carry out the treatment of general doctors. By analyzing D.O.'s specialization strategy, this study intends to preview points for establishing the future role of Korean Medicine doctors. Methods : We searched books, research papers, reports, conference presentations, and media articles, and chronologically classified and organized the collected data. In addition, the latest update information on related institutions' web pages and expert opinions released were also reviewed. Results : The D.O. emerged as a form of doctor in alternative medicine, however it rapidly turned to an M.D. substitute during the pandemic of the 1910s and World War II in the 1940s. Through the American Osteopathic Association (AOA)'s organizational activity, curriculum specialization, research development, and financial support, D.O. now has secured the status of M.D. in 50 states and federal law in the US. It has its own and exclusive full practice rights, capable of prescribing drugs and practicing surgery, as well as manual therapy. Beginning in July 2020, M.D.-D.O. achieved the full integration-unification of the professional training and residency program. Conclusions : In order to introduce the D.O. model to Korean Medicine system, it is necessary to strengthen biomedicine in the curriculum, and significantly expand the educational infrastructure and faculty manpower.

• Structural Engineering and Mechanics
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• 제86권3호
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• pp.337-348
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• 2023

The optimization of reinforced concrete (RC) cantilever retaining walls is a complex problem and requires the use of advanced techniques like metaheuristic algorithms. For this purpose, an optimization model must first be developed, which involves mathematical complications, multidisciplinary knowledge, and programming skills. This task has proven to be too arduous and has halted the mainstream acceptance of optimization. Therefore, it is necessary to unravel the complications of optimization into an easily applicable form. Currently, the most commonly used method for designing retaining walls is by following the proportioning limits provided by the ACI handbook. However, these limits, derived manually, are not verified by any optimization technique. There is a need to validate or modify these limits, using optimization algorithms to consider them as optimal limits. Therefore, this study aims to propose updated proportioning limits for the economical design of a RC cantilever retaining wall through a comprehensive parametric investigation using the genetic algorithm (GA). Multiple simulations are run to examine various design parameters, and trends are drawn to determine effective ranges. The optimal limits are derived for 5 geometric and 3 reinforcement variables and validated by comparison with their predecessor, ACI's preliminary proportioning limits. The results indicate close proximity between the optimized and code-provided ranges; however, the use of optimal limits can lead to additional cost optimization. Modifications to achieve further optimization are also discussed. Besides the geometric variables, other design parameters not covered by the ACI building code, like reinforcement ratios, bar diameters, and material strengths, and their effects on cost optimization, are also discussed. The findings of this investigation can be used by experienced engineers to refine their designs, without delving into the complexities of optimization.

• Journal of Korea Trade
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• 제27권3호
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• pp.199-216
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• 2023

Purpose - This study aims to identify the internal capabilities that export companies need to possess in order to utilize FTAs and to propose ways to expand their export performance through them. To achieve this goal, the study analyzed the internal factors that affect FTA utilization from a resource-based perspective, such as Origin Management Competency, Information Acquisition Competency, contract Management Competency, and Commitment to Export, based on prior research on corporate capabilities in the field of management and FTA-related research. The study ultimately aims to confirm whether a company's FTA utilization contributes to its export performance through the management and response to its internal factors for FTA utilization. Design/methodology - To achieve the research objective, this study conducted a literature review related to FTA utilization and identified the internal factors of companies that affect FTA by classifying them into Origin Management Competency, Information Acquisition Competency, contract Management Competency, and Commitment to Export Based on this, a final research model was developed, hypotheses were set through a preliminary study survey, and conclusions were drawn by analyzing the data of 312 companies. Findings - The empirical analysis results indicate that Origin Management Competency and Contract Management Competency have a positive impact on FTA utilization, while Information Acquisition Competency and Commitment to Export do not have a statistically significant impact on FTA utilization. Based on these findings, this study suggests measures for efficient FTA utilization for companies that want to utilize FTAs. Additionally, FTA utilization has a positive impact on export performance. In other words, the extent to which companies utilize the signed agreements has a positive impact on their performance. Based on these results, this study identifies the characteristics of companies that want to utilize FTAs and proposes measures for future efficient FTA utilization. Originality/value - This study has confirmed that in order for companies to utilize FTAs, they must meet the requirements of the FTA. To this end, the study has concluded that it is important to manage and address internal factors such as Origin Management Competency, Information Acquisition Competency, contract Management Competency, and Commitment to Export to increase FTA utilization. Based on these results, it can be confirmed that it is essential for companies to have an understanding and management of the internal factors that satisfy the requirements of the FTA in order to utilize the FTA.

• Journal of Korea Trade
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• 제27권1호
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• pp.42-59
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• 2023

Purpose - As a leading source of foreign exchange and investment, tourism has grown in importance as a component of international trade. Accordingly, in recent decades much attention has been directed toward attracting foreign tourists and, in turn, positively affecting the recommendation intentions of foreign tourists. Despite such interests, there remains a dearth of empirical research on this issue. Moreover, prior research has focused primarily on the simple main effect of a certain factor on recommendation intentions. Therefore, the present study aims to (1) investigate the effect of overall satisfaction on the recommendation intentions of foreign tourists, and (2) examine the potential moderating effects of personal factors (i.e., age and destination image) on the association between overall satisfaction and recommendation intention. Design/methodology - Using a moderated moderation analysis of the data drawn from the 2018 International Visitor Survey conducted by the Korea Tourism Organization, this study proposes the three-way interaction effects of overall satisfaction, age, and destination image on recommendation intention. Findings - The findings of the study indicate that overall satisfaction is positively associated with recommendation intention and this relationship becomes stronger among younger tourists. The findings further indicate that the moderating effect of age on the relationship between overall satisfaction and recommendation intention depends on changes in the image of the destination. Specifically, the destination image exerts a positive moderating impact on the influence of age that moderates the overall satisfaction and recommendation intention relationship. Originality/value - Considering that the tourism economy has been severely affected by the current COVID-19 pandemic, this study contributes to a more accurate understanding of the factors affecting the recommendation intention, especially in times of crisis.