• 한국항공우주학회지
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• 제35권9호
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• pp.799-804
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• 2007

액체추진제 추력기 연소실의 인젝터로부터 발생하는 분무 거동을 파악하기 위하여 광학계측 기법을 사용한다. 실험에 사용된 인젝터는 지름이 0.406 mm이며 중심축으로부터 30 의 경사각을 이루는 8 개의 노즐 구멍으로 구성된다. 분무생성의 초기조건과 분무발달에 따른 미립화 과정을 분석하기 위해, 이중모드 위상도플러속도계(DPDA)로 측정된 액적의 속도 및 입경 등의 변이 거동을 제시하고 Nd:Yag 레이저평면광에 의해 획득된 순간평면이미지와 함께 고찰한다. 분무액적의 초기 분사속도에 근거한 Re 수와 We 수 등의 무차원 변수를 도출하여 인젝터 발생 분무의 미립화 및 난류성질 등에 대한 분무유동 양식의 범주를 결정한다. 이러한 분무분열에 대한 정성적, 정량적 결과는 향후 새로운 추력기 개발에 확실한 설계 기반을 제공할 것이다.

• 대한기계학회논문집
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• 제8권5호
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• pp.442-449
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• 1984

본 연구에서는 두 분류가 교우되어 배합이 이루어지는 유동역에서 3차원 방향 에 대하여 평균속도분포, 난류강도분포, 난류전단응력분포, 상관계수의 분포 및 난류 운동에너지와 운동량의 변화 등을 측정 분석하였다.

• 대한기계학회논문집B
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• 제25권6호
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• pp.786-798
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• 2001

This paper describes the phenomena of wake-induced transition of the boundary layers on a NACA0012 airfoil using measured phase-averaged data. Especially, the phase-averaged wall shear stresses are reasonably evaluated using the principle of Computational Preston Tube Method. Due to the passing wake, the turbulent patch is generated in the laminar boundary layer on the airfoil and the boundary layer becomes temporarily transitional. The patches propagate downstream with less speed than free-stream velocity and merge with each other at further down stream station, and the boundary layer becomes more transitional. The generation of turbulent patch at the leading edge of the airfoil mainly depends on velocity defects and turbulent intensity profiles of passing wakes. However, the growth and merging of turbulent patches depend on local streamwise pressure gradients as well as characteristics of turbulent patches. In this transition process, the present experimental data show very similar features to the previous numerical and experimental studies. It is confirmed that the two phase-averaged mean velocity dips appear in the outer region of transitional boundary layer for each passing cycle. Relatively high values of the phase-averaged turbulent fluctuations in the outer region indicate the possibility that breakdown occurs in the outer layer not near the wall.

• 자원환경지질
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• 제29권5호
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• pp.597-613
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• 1996

The tonnage of copper and tungsten produced at Dalseong mine by Taehan Tungsten Mining Company from 1961 to 1971 was 48,704 tons (M/T) of 4 wt.% Cu and 1,620 tons (S/T) of 70wt.% WO, but the mine was closed in 1974. Kyeongsan mine is a small abandoned cobalt mine with no data of production. To investigate the pollution level of the mine areas, soils, plants (Ohwi and Pampanini), stream waters and stream sediments were taken and Fe, Mn, Cu, Pb, Zn, Ni, Co, Cd and Cr were analysed by ICP. Soils are considerably contaminated by the heavy metals related to ore deposits, The heavy metal contents in plants vary with the species and parts of plants. Stream waters are anomalously high in heavy metals in the vicinity of the mines but the contents decrease downstream in the process of dilution and precipiation. However, heavy metal contents increase very high in stream sediments due to precipiation. To protect environmental damages caused by acid mine drainages wetlands must be constructed outside pits, and it is necessary to fill pits with waters, limestone chips and organic materials, which give reducing and alkaline condition to ores. Under the condition pyrite is protected from oxidation and aqueous iron sulphates precipitate to form stable secondary pyrite.

• Asian-Australasian Journal of Animal Sciences
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• 제33권1호
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• pp.4-11
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• 2020

Objective: Puerarin has the potential of regulating the differentiation of preadipocytes, but its mechanism of action has not yet been elucidated. Adipocytes found in adipose tissue, the main endocrine organ, are the main sites of lipid deposition, and are widely used as a cell model in the study of in vitro fat deposition. This study aimed to investigate the effects of puerarin on adipogenesis in vitro. Methods: Puerarin was added to the culture medium during the process of adipogenesis. The proliferation and differentiation of bovine preadipocytes was measured through cell viability and staining with oil red O. The content of triacylglycerol was measured using a triglyceride assay kit. The mRNA and protein expression levels of adipogenic genes, peroxisome proliferator-activated receptor-γ (PPARγ) and CCAAT/enhancer-binding protein-α, were measured using quantitative real-time polymerase chain reaction and western blotting, respectively. Results: The addition of puerarin significantly increased adipogenesis of bovine preadipocytes and enhanced the mRNA and protein level expression of PPARγ (p<0.01). The expression of P-Akt increased after adipogenic hormonal induction, whereas puerarin significantly increased PPARγ expression by promoting the Akt signaling component, P-Akt. The mechanism of adipogenesis was found to be related to the phosphorylation level of Ser473, which may activate the downstream signaling of the Akt pathway. Conclusion: Puerarin was able to promote the differentiation of preadipocytes and improve fat deposition in cattle. The mechanism of adipogenesis was found to be related to the phosphorylation level of Ser473.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2002년도 생물공학의 동향 (X)
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• pp.112-115
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• 2002

본 연구에서는 균주의 배양과 동시에 생산물을 회수할 수 있는 동시추출공정을 건조질량의 $15{\sim}75$ %의 탄화수소를 생산한다고 알려진 B. braunii 배양에 적용하고자 한다. 일반적인 tow-phase 동시 추출공정의 적용시 B. braunii의 경우 생산된 탄화수소가 균주 외벽의 matrix에 강하게 부착되어 있기 때문에, two phase 추출공정 적용시 bubble solumn내에서 단지 폭기에 의한 교반만으로는 충분한 탄화수소의 회수율을 얻을 수가 없었다. 본 연구에서는 배양액과 유기용매층의 접촉기회를 증대시킨 two-stage 동시추출 공정을 개발하여 기존의 two-stage 동시추출 공정보다 2배 이상 높은 57 %의 탄화수소 회수율을 얻을 수가 있었고, 이를 회분배양후 후속분리공정으로 이용할 경우 6시간 추출후 62 %의 회수율을 얻을 수가있었다.

• 한국유체기계학회 논문집
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• 제14권6호
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• pp.96-101
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• 2011

Korea Aerospace Research Institute is performing 3 stage transonic axial compressor development program. This paper introduces design step of the compressor, the performance test results and its analysis. In the fore part of the paper, aerodynamic process of the 3 stage axial compressor is presented. To satisfy both of the mass flow and pressure rise, the compressor should rotate at a high rotational speed. Therefore the transonic flow field forms in the rotor stages and it is designed with a relatively high pressure rise per stage to satisfy its design target. The compressor stage consists of 3 stages, and the bulk pressure ratio is 2.5. The first stage is burdened with the highest pressure ratio and less pressure rises occur in the following stages. Also it is designed that tip Mach number of the first rotor row does not exceed 1.3, while the maximum relative Mach number in the rotor stage is between 1.3~1.4 to increase the compressor flow coefficient. The final design has been confirmed by iterating three dimensional CFD calculations to verify design target and some design intentions. In the latter part of the paper, its performance test processes and results are presented. The performance test result shows that the overall compressor performance targets; pressure ratio and efficiency are well achieved. The stator static pressure distributions show that the blade loading is gradually increasing from the downstream of the compressor.

• 한국추진공학회지
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• 제12권1호
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• pp.57-63
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• 2008

공기흡입식 추진 기관인 스크램제트 엔진은 연소기 내부 유동이 초음속으로 유동장의 연소기 내부 체류 시간이 수 ms로 매우 짧다. 이 짧은 시간동안 연소과정이 모두 이루어져야 하므로 초음속 연소기술에 대한 연구는 매우 중요하다. 본 논문은 초음속 연소 기술 중 연료-공기의 혼합을 증대시키는 방법에 관심을 두고 Cavity를 이용한 방법을 선택하여 높이를 10mm로 고정시키고 길이를 변화시켰으며, Cavity 후류에서 지름 1mm의 분사구를 통해 음속 let을 분사시키는 유동장을 형성하여 3차원 Navier-Stokes 방정식을 통해 점성 유동장을 해석하였다. 해석 결과 Cavity 길이/높이비(L/H)가 클수록 Vorticity가 값이 증가하였고 Vorticity의 증가 영역이 유동장의 위, 옆 방향으로 확장되는 것을 볼 수 있었다. 하지만 Vorticity가 증가하는 만큼 추력특성을 떨어뜨리는 정체압력 손실이 증가하므로 연소기 설계 시 최대의 혼합과 최소의 정체압력 손실을 고려한 최적 형상 설계가 필요하다는 것을 확인하였다.

• 대한한방내과학회지
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• 제24권1호
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• pp.113-122
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• 2003

Objective : The aim of this study was to evaluate the efficacy of Gagamchunggan-tang on anti-inflammation reaction with lipopolysaccharide (LPS)-induced HepG2 cell. Method : We examined the effects of the Gagamchunggan-tang, a traditional drug for liver inflammation, on the process of lipopolysaccharide(LPS)-induced nuclear factor-${\kappa}Bp65(NF-{\kappa}Bp65)$ activation in HepG2 cell. SDS-PAGE, Western blotting, Immunofluorescence staining were studied. Results : Immunoblot analysis showed that the level of nucleic $NF-{\kappa}Bp65$ was rapidly up-regulated and cytosolic inhibitory $I-{\kappa}B{\alpha}$ was down-regulated by LPS challenge. While Gagamchunggan-tang inhibited an increase of $NF-{\kappa}Bp65$ and degradation of $I-{\kappa}B{\alpha}$ in HepG2 cell. Besides LPS-induced expression of a group of genes, such as tumor necrosis factor-${\alpha}(TNF-{\alpha})$, inducible nitric oxide synthase(iNOS) and cyclooxygenase-2 (COX-2), are repressed by Gagamchunggan-tang. It may be concluded that Gagamchunggan-tang attenuates the progress of LPS-induced inflammation by reduction of $NF-{\kappa}Bp65$ activation. Conclusion : The Gagamchunggan-tang would be useful as a therapeutic agent for endotoxin-induced liver disease.

• Parasites, Hosts and Diseases
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• 제49권1호
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• pp.9-15
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• 2011

To understand the distribution of Giardia cysts in drinking water supplies in Seoul, Korea, we collected water samples quarterly at 6 intakes in the Han River, its largest stream and 6 conventional water treatment plants (WTPs) serving drinking water, from 2000 to 2009. Giardia cysts in each of 10 L water were confirmed in 35.0% of intake water samples and the arithmetic mean was 1.65 cysts/10 L (range 0-35 cysts/10 L). The lowest cyst density was observed at Paldang and Kangbuk intakes, and the pollution level was higher at 4 intakes downstream. It seemed that these 4 intakes were under influence of Wangsuk stream at the end of which cysts were found in all samples with the mean of 140 cysts/10 L. The annual mean number of cysts was 0.21-4.21 cysts/10 L, and the cyst level at the second half of the 10 years was about 1/5 of that at first half on average. The cysts were more frequently found in winter, and their mean density was 3.74 cysts/10 L in winter and 0.80-1.08 cysts/10 L in other seasons. All finished water samples collected at 6 WTPs were negative for Giardia in each of 100 L sample for 10 years and cyst removal by physical process was average 2.9-log. It was concluded that conventional water treatment at 6 WTPs of Seoul appears to remove the cysts effectively under the present level of their source water. Domestic wastewater from the urban region could be an important source of Giardia pollution in the river.