• Title/Summary/Keyword: Down-aging

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Walking Assistance Robot Design and Development (보행 보조 로봇의 설계 및 개발)

  • Lee, Min-Gyu;Lee, Yong-Hoon;Yim, Hong-Jae;Lee, Yong-Kwun
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2008.04a
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    • pp.585-592
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    • 2008
  • The aging society comes, the number of the old people expended. Technical aids allow elderly and handicapped people to live independently in their private homes as long as they wish. As a contribution to these required technological solutions, a demonstrator platform for a walking assistance robot. robot which has the capability to perform fetch and carry and various other supporting tasks. In this study, we addresses the development of a walking assistance robot system. We execute static analysis, vibration analysis and flexible dynamics to reserve stability at the design. Each motion of the robot uses a linear actuator and gears. Motion can be distinguished into 3 parts depending on the up & down, rotation, and cushion trans. In each motion, we compare the displacement of the case to be rigid with the case to be flexible. As a result, manufactured and feasibility of the walking assistance robot is validated through preliminary experiments.

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The Extraction of Nb from Nitric Acid Solution by Mixture of Tributylphosphate(TBP) and Dibutylphosphate(DBP) (窒酸溶液에서의 Tributylphosphate (TBP), Dibutylphosphate (DBP)混合物에 依한 Nb의 抽出)

  • Yung Kook Kim
    • Journal of the Korean Chemical Society
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    • v.7 no.1
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    • pp.38-41
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    • 1963
  • Nb is one of the trouble-some fission products in the reprocessing of nuclear fuels. In this paper, the extraction of Nb from 1, 2, 3, 4, 6 and 9N $HNO_3$ solution by mixtures of TBP and DBP in dodecane are reported. Sums of the concentration of TBP and DBP are kept to 20%. When the concentrations of DBP are lower the $2{\times}10^{-2}%$, distribution ratios are almost same, and ratios increase abruptly and the slope is about 2.5 at between $2{\times}10^{-2}$ to $4{\times}10^{-1}%$, then slope falls down to about 0.5. There is aging effect on mixture of TBP and DBP.

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Image Support and Wood Identification of Wood Crafts (I) - Focusing on Wooden Containers - (목공예품의 이미지제공 및 수종분석(I) - 목기류를 중심으로 -)

  • Kim, Sa-Ick
    • Journal of the Korea Furniture Society
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    • v.25 no.3
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    • pp.198-204
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    • 2014
  • Aggravation of natural environment, improvements in income, internet diffusion, spread of five-day work a week, and population aging seem very different from each other. However they boil down to consumption. These culture patterns are changing into environment-friendly and productive housing culture. In other words, people might tend to have frequent contacts with not only environment-friendly housing in bustling cities but also woods that is environment friendly materials in their leisure time. In the period of people young and old alike are in favor of woodcrafts, this study was conducted for giving information to who speicalized in woodcrafts. Furthermore, the study shows that other countries also added grain and figure to woodcrafts for visually appealing.

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A Theoretical Study and Implementation of Spinal Traction System (척추견인 시스템의 인체 역학적 견인력에 대한 이론적 고찰 및 구현에 관한 연구)

  • Chang, Hojong;Lee, Song Jae
    • Journal of Biomedical Engineering Research
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    • v.35 no.2
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    • pp.19-25
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    • 2014
  • According to recent data more than 80% of people suffer from back pain, due to an aging and a poor posture, at least once in their life time, and 7~10% of them have chronic spine illness. Researchers over the years have studied on various spinal traction devices that utilize the force of traction, and have also reported clinical test results. However, most existing devices are too complicated and too expensive. In order to solve these problems, we have developed a new device in which the frame moves up and down and at the same time tilting angle of the frame is adjusted. We have analyzed the forces applied on the body as a function of tilting angle. And the result shows that the new device has achieved the force of traction, which is known to be effective for spinal rehabilitation.

A Study on The Prediction of Number of Failures using Markov Chain and Fault Data (마코프 체인과 고장데이터를 이용한 고장건수 예측에 관한 연구)

  • Lee, Hee-Tae;Kim, Jae-Chul
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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    • 2008.10a
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    • pp.363-366
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    • 2008
  • It was accomplished that failure analysis not only failure numbers but also power system components every years. and these informations help power system operation considerably. power system equipment were occurred a break down by natural phenomenon and aging but it was not able to predict this failure number. But many papers and technical repots study for each equipment failure rate and reliability evaluation methods. so this paper show a failure number prediction whole power system component using Markov theory not each component failure probability. the result present a next month system failure number prediction.

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A Study on the Architectural Planning of the Hospital for the Elderly with Dementia (치매노인전문병원의 건축계획에 관한 연구)

  • Lee, Jung Min;Yu, Young Min
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.7 no.1
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    • pp.85-92
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    • 2001
  • Facing the aging society in Korea, the necessity of the facility for the elderly is arising as a substitute to cut down the cost and to provide suitable and skillful medical services for the aged and chronical. Among there, health care facilities for the elderly with dementia are considered a essential facility. Therefore, it is necessary to prepare the guidelines for planning and design of the facility. On the bases of survey and analysis, the basic data for planning and design the hospital for the elderly with dementia has been proposed.

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Development of An Intelligent Tilt Table for Paralytic Patients (편마비 환자를 위한 틸트 테이블 구동장치 개발)

  • Kim, S.H.;Cho, J.M.;Nam, T.W.;Lim, J.H.;Pack, S.I.
    • Journal of Biomedical Engineering Research
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    • v.27 no.5
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    • pp.260-266
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    • 2006
  • Due to damaged vertebrae nerves, serious disease and aging, patients who have to lie down for long period of time need to exercise to maintain up-right standing position and recover their paralytic leg. This study describes a development of an intellectual tilt table which can provide a patient with rehabilitating condition. This can be possible by measuring and displaying the hee bent angle and pressure for each foot during exercise in real time. It is expected that the patient's exercising effect can increase by monitoring these two values during exercise.

Effect of kimchi on the Microbiological properties of fermented sausages during ripening period (김치 첨가가 발효소세지 숙성중 미생물 특성에 미치는 영향)

  • 한영실;김순임;정해옥;전희정;백재은
    • Korean journal of food and cookery science
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    • v.17 no.3
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    • pp.224-228
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    • 2001
  • We studied the effects that the addition of Kimchi has on microbiological properties of fermented sausages as we observed pH and microbiological changes of Kimchi-added fermented sausage by aging period. The pH figure of sausages added with commercial starter culture was 5.69 at the beginning stage and declined gradually to 5.01. The more Kimchi is added, the lower pH figure goes. Sausages with 10% and 20% of fresh Kimchi, and 2% and 4% of powdered Kimchi added, showed about pH 5.4 at the early stage and down to pH 4.87 as they are stored longer. In terms of microbiological changes, sausages mixed with starter culture showed 10$\^$7/cfu/g level in the number of total bacteria, lactic acid bacteria, yeast and fungi, lower than Kimchi-added sausages. However, the figure soared sharply to 10$\^$10/cfu/g during the aging period. Kimchi-added sausages recorded 10$\^$9/cfu/g, slightly high during the eurly aging stage, in the number of total bacteria, lactic acid bacteria, yeast and fungi, while showing a gradual increase up to 10$\^$10/cfu/g towards the end of aging period and became microbiologically stabilized.

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Inhibitory Activity of Blueberries on UVB-induced Oxidative Stress and Matrix Metalloproteinase Expression in Human Skin Fibroblasts (인간피부 섬유아세포에서 UVB 유도된 산화 스트레스와 기질금속단백질가수분해효소 발현에 블루베리의 저해능)

  • Jang, Young Ah;Kim, Se Gie
    • Journal of Life Science
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    • v.29 no.12
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    • pp.1321-1328
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    • 2019
  • Intermediate-wavelength solar radiation, also known as ultraviolet B (UVB: 290-320 nm) radiation, may cause premature aging and oxidative damage-dependent skin cancer in humans. UVB-induced formation of reactive oxygen species (ROS)-often a consequence of excessive exposure to these rays-could activate matrix metalloproteinases (MMPs) such as MMP-1 and MMP-3. These enzymes break down type I collagen in human fibroblasts. In this study, we assessed the antioxidant and anti-aging effects of ethyl acetate extract of blueberry (EEB). An antioxidant test in blueberries evaluated ROS production using CCD-986sk cells and DPPH assay. In order to evaluate the anti-wrinkle efficacy of blueberries, the MMP-1 production and type 1 procollagen synthesis evaluated and the expression of MMP 1, 3 were tested through Western blot and RT- PCR. EEB exhibited 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and reduced the production of UVB-induced ROS. Also, EEB inhibited UVB-induced processes associated with photoaging and skin cancer, such as reduction in procollagen production and increase in MMP-1 production. More precisely, EEB (50 ㎍/ml) markedly suppressed mRNA and protein levels of MMP-1 and -3. The anti-aging effects are attributable to the antioxidant activity of EEB. These findings indicate that EEB has a protective effect against UVB-induced aging in human fibroblast cells by regulating the levels of type-1 procollagen, MMP-1, and MMP-3.

Saponins from Panax japonicus ameliorate age-related renal fibrosis by inhibition of inflammation mediated by NF-κB and TGF-β1/Smad signaling and suppression of oxidative stress via activation of Nrf2-ARE signaling

  • Gao, Yan;Yuan, Ding;Gai, Liyue;Wu, Xuelian;Shi, Yue;He, Yumin;Liu, Chaoqi;Zhang, Changcheng;Zhou, Gang;Yuan, Chengfu
    • Journal of Ginseng Research
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    • v.45 no.3
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    • pp.408-419
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    • 2021
  • Background: The decreased renal function is known to be associated with biological aging, of which the main pathological features are chronic inflammation and renal interstitial fibrosis. In previous studies, we reported that total saponins from Panax japonicus (SPJs) can availably protect acute myocardial ischemia. We proposed that SPJs might have similar protective effects for aging-associated renal interstitial fibrosis. Thus, in the present study, we evaluated the overall effect of SPJs on renal fibrosis. Methods: Sprague-Dawley (SD) aging rats were given SPJs by gavage beginning from 18 months old, at 10 mg/kg/d and 60 mg/kg/d, up to 24 months old. After the experiment, changes in morphology, function and fibrosis of their kidneys were detected. The levels of serum uric acid (UA), β2-microglobulin (β2-MG) and cystatin C (Cys C) were assayed with ELISA kits. The levels of extracellular matrix (ECM), matrix metalloproteinases (MMPs), tissue inhibitors of metalloproteinases (TIMPs), inflammatory factors and changes of oxidative stress parameters were examined. Results: After SPJs treatment, SD rats showed significantly histopathological changes in kidneys accompanied by decreased renal fibrosis and increased renal function; As compared with those in 3-month group, the levels of serum UA, Cys C and β2-MG in 24-month group were significantly increased (p < 0.05). Compared with those in the 24-month group, the levels of serum UA, Cys C and β2-MG in the SPJ-H group were significantly decreased. While ECM was reduced and the levels of MMP-2 and MMP-9 were increased, the levels of TIMP-1, TIMP-2 and transforming growth factor-β1 (TGF-β1)/Smad signaling were decreased; the expression level of phosphorylated nuclear factor kappa-B (NF-κB) was down-regulated with reduced inflammatory factors; meanwhile, the expression of nuclear factor erythroid 2-related factor 2-antioxidant response element (Nrf2-ARE) signaling was aggrandized. Conclusion: These results suggest that SPJs treatment can improve age-associated renal fibrosis by inhibiting TGF-β1/Smad, NFκB signaling pathways and activating Nrf2-ARE signaling pathways and that SPJs can be a potentially valuable anti-renal fibrosis drug.