• Archives of Plastic Surgery
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• 제46권6호
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• pp.558-565
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• 2019

Background The scalp, an excellent donor site for thin skin grafts, presents a limited surface but is rich in stem cells. The purpose of this study was to test a double harvesting procedure from the scalp and to evaluate the capacity of the dermal layer. Methods Two layers corresponding to a split-thickness skin graft (SSG) and a split-thickness dermal graft (SDG) were harvested from the scalp using a Zimmer dermatome during the same procedure. Healing of the scalp donor site, reason for recipient site grafting, and the percentage of graft loss were evaluated. Results Fourteen patients, comprising six men and eight women with a mean age of 34.2 years, were treated according to our protocol. The most common reason for a recipient site graft was a postburn scar deformity (10/14 patients). The mean area of scalp SSGs was 151.8 cm². The mean area of scalp SDGs was 88.2 cm². The mean healing time of scalp donors was 9.9 days. The only donor complication was a tufted scar deformity. Conclusions Skin defects in the scalp of donors healed faster and led to less scarring than defects at other donor sites. Scalp SDGs needed 10 days for adequate epithelization. The scalp was the best donor site for SSGs and SDGs for burn reconstructive patients.

• 한국의학물리학회지:의학물리
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• 제30권4호
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• pp.89-93
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• 2019

Purpose: This study aims to develop new markers based on silicone rubber and urethane rubber to enhance visibility in low magnetic field magnetic resonance (MR) imaging. Methods: Four types of markers were fabricated using two different base materials. Two of the markers were composed of two different types of silicone rubber: DragonSkin™ 10 MEDIUM and BodyDouble™ SILK. The other two markers were composed of types of urethane rubber: PMC™ 780 DRY and VytaFlex™ 20. Silicone oil (KF-96 1000cs) was added to the fabricated markers. The allocated amount of oil was 20% of the weight (wt%) of each respective marker. The MR images of the markers, with and without the silicone oil, were acquired using MRIdian with a low magnetic field of 0.35 T. The signal intensities of each MR image for the markers were analyzed using ImageJ software and the visibility for each was compared. Results: The highest signal intensity was observed in VytaFlex™ 20 (279.67±3.57). Large differences in the signal intensities (e.g., 627% in relative difference between BodyDouble™ SILK and VytaFlex™ 20) among the markers were observed. However, the maximum difference between the signal intensities of the markers with the silicone oil showed only a 62% relative difference between PMC™ 780 DRY and DragonSkin™ 10 MEDIUM. An increase in the signal intensity of the markers with the silicone oil was observed in all markers. Conclusions: New markers were successfully fabricated. Among the markers, DragonSkin™ 10 MEDIUM with silicone oil showed the highest MR signal intensity.

• 한국군사과학기술학회지
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• 제24권1호
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• pp.1-11
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• 2021

Thermal protection system structures such as double-panel structures are used on the skin of the fuselage and wings to prevent the transfer of high heat into the interior of an high supersonic/hypersonic aircraft. The thin-walled double-panel skin can be exposed to acoustic loads by high power engine noise and jet flow noise, which can cause sonic fatigue damage. In order to predict the fatigue life of the skin, the octave bandwidth SPL should be calculated as narrow bandwidth PSD or acoustic load history using interpolation method. In this paper, a method of converting the octave bandwidth SPL acoustic load into a narrow bandwidth PSD and reconstructed acoustic load history was investigated. The octave bandwidth SPL was converted to the narrow bandwidth PSD using various interpolation methods such as flat, log and linear scale, and the probabilistic characteristics and fatigue damage results were compared. It was found that average error of fatigue damage index by the log scale interpolation method was relatively small among three methods.

• Archives of Plastic Surgery
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• 제32권3호
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• pp.299-303
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• 2005

The epicanthal fold is common natural finding in Asian eyes. It is very common that patients, who look for oriental blephaloplasty for double eye lid, request correction epicanthal fold. It is very often difficult to achieve satisfactory results if the correction of the epicanthal fold is not corrected concomitantly. Many authors described surgical procedures for correction of epicanthal folds. But most of them leave additional scars which tend to be hypertrophic and noriceable. We achieved satisfactory result in epicanthoplasty with invisible scar, using combination of procedures, such as upward incision, double eyelid operation, anchoring suture of the medial upper lid skin to the medial canthal tendon, trans-nasal root subcutaneous mattress suture of the epicanthal fold itself and combined rhinoplasty. For past six years (1998 to 2003) 17 patients have been operated with one of these mentioned procedures. The mean follow up was 4months (2weeks to 6months). All patients were satisfied and no major complication was noted. This method can be one of the effective procedures for correcting the Asian epicanthal fold for avoiding potential visible scar and ancillary procedure in double eye lid blephaloplasty.

• Safety and Health at Work
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• 제6권3호
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• pp.256-262
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• 2015

Background: Heart attack is the most common cause of line-of-duty death in the fire service. Daily aspirin therapy is a preventative measure used to reduce the morbidity of heart attacks but may decrease the ability to dissipate heat by reducing skin blood flow. Methods: In this double-blind, placebo-controlled, crossover study, firefighters were randomized to receive 14 days of therapy (81-mg aspirin or placebo) before performing treadmill exercise in thermal-protective clothing in a hot room [$38.8{\pm}2.1^{\circ}C$, $24.9{\pm}9.1%$ relative humidity (RH)]. Three weeks without therapy was provided before crossing to the other arm. Firefighters completed a baseline skin blood-flow assessment via laser Doppler flowmetry; skin was heated to $44^{\circ}C$ to achieve maximal cutaneous vasodilation. Skin blood flow was measured before and after exercise in a hot room, and at 0 minutes, 10 minutes, 20 minutes, and 30 minutes of recovery under temperature conditions ($25.3{\pm}1.2^{\circ}C$, $40.3{\pm}13.7%\;RH$). Platelet clotting time was assessed before drug administration, and before and after exercise. Results: Fifteen firefighters completed the study. Aspirin increased clotting time before and after exercise compared with placebo (p = 0.003). There were no differences in absolute skin blood flow between groups (p = 0.35). Following exercise, cutaneous vascular conductance (CVC) was $85{\pm}42%$ of maximum in the aspirin and $76{\pm}37%$ in the placebo groups. The percentage of maximal CVC did not differ by treatment before or after recovery. Neither maximal core body temperature nor heart rate responses to exercise differed between trials. Conclusion: There were no differences in skin blood flow during uncompensable heat stress following exercise after aspirin or placebo therapy.

• 대한두개안면성형외과학회지
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• 제22권4호
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• pp.183-192
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• 2021

Background: The purse-string suture (PSS) is a simple and rapid wound closure method that results in minimal scarring. It has been used to treat circular or oval skin defects caused by tumor excision or trauma. However, due to obscurity, it is not widely used, especially for the head and neck. This study aimed to modify the PSS to obtain predictable and acceptable results. Methods: A total of 45 sites in 39 patients with various types of skin and soft tissue defects in the head and neck were treated with PSS. We used PDS II (2-0 to 5-0), which is an absorbable suture. Minimal dissection of the subcutaneous layer was performed. The suture knot was hidden by placing it in the dissection layer. Depending on the characteristics of the skin and soft tissue defects, additional surgical interventions such as side-to-side advancement sutures, double PSS, or split-thickness skin graft were applied. Results: All wounds healed completely without any serious complications. Large defects up to 45 mm in diameter were successfully reconstructed using only PSS. Postoperative radiating folds were almost flattened after approximately 1-2 months. Conclusion: PSS is simple, rapid, and relatively free from surgical design. Owing to the circumferential advancement of the surrounding tissue, PSS always results in a smaller scar than the initial lesion and less distortion of the body structures around the wound in the completely healed defect. If the operator can predict the process of healing and immediate radiating folds, PSS could be a favorable option for round skin defects in the head and neck.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제27권1호
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• pp.66-70
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• 2005

이차 구순비성형술을 받고자 본과에 내원한 편측성 완전 구순구개열을 가진 29세 남자 환자에서 상방으로 반전된 큐피드활과 적순부의 휘파람 변형을 교정하기 위해 중복 Z-성형술을 시행하였다. 수술 후에 반전된 큐피드활이 정상적인 형태로 재건되고 휘파람 변형이 없어졌으며 상순의 긴장도가 완화되었다. 중복 Z-성형술시 적순부 내에서만 피판을 형성하므로 피부에는 새로운 반흔이 생기지 않아 심미적으로 만족스러웠고 상순결절은 더욱 볼록해 졌다. 수술 4년경과 후 큐피드활은 부드러운 곡선으로 좌우 대칭을 이루고 매우 자연스럽게 보였으며 장기적인 추적관찰 결과 양호한 결과를 보였다. 중복 Z-성형술은 반전된 큐피드활의 교정시 다른 수술방법에 비해 술식이 간단하고 주위조직 손상이 적으며 휘파람 변형의 교정도 가능한 좋은 방법이라고 사료된다.

• 한국산학기술학회논문지
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• 제13권7호
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• pp.2886-2894
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• 2012

본 연구는 서울소재 대학교에 재학 중인 여대생을 대상으로 피부미용전공과 비전공 여학생들의 피부건강관리의 관심도와 피부상태, 인식 및 관리 행위의 차이점 및 관련성을 파악하고자 하였다. 전공자들과 비전공자들의 대한 비교 분석은 동일한 생활권에서 궁극적으로 전문 학습과 비 전문학습의 일반적인 상태에 대한 지식과 행위를 의미하는 것으로, 연구결과는 다음과 같이 나타났다. 전공 여대생이 비전공 여대생에 비해 피부건강에 대한 관심도가 높은 것으로 유의미한 차이가 있었다(p<.01). 피부미용 전공 여대생은 복합성 피부, 비전공 여대생은 건성 피부가 많은 것으로 유의미한 차이를 보였다(p<.05). 피부 관리 실태에서 색조화장 후 전공여부에 따른 이중세안 정도, 각질 정리 횟수, 마사지나 팩 관리횟수, 선크림 사용 항목에서 각각 유의미한 차이가 있었다(p<.01, p<.001, p<.01, p<.01). 오백식품 및 인스턴트식품의 영향정도와 수분섭취 항목에서 각각 유의미한 차이를 보였다(p<.001).(p<.05). 화장품 사용은 다양한 채널을 통해 효율적인 구매를 하는 경향이었으며, 탁월한 기능이 있을 때는 경제적 부담이 있어도 구입 의향 항목에서 적극적인 성향인 것으로 유의미하게 나타났다(p<.001). 본 연구의 결과는 피부미용 산업 및 교육 분야에 기초자료로 활용되고자 하였다.

• Journal of Nutrition and Health
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• 제52권2호
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• pp.149-156
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• 2019

본 연구에서는 12주간 김치에서 추출한 유산균 Lactobacillus plantarum 섭취가 피부의 산도 및 관련인자인 유리아미노산, 젖산 및 유리지방산의 함량을 변화시키는지 파악하였다. CJLP 군에서 12주차에 피부 산도가 대조군에 비해 개선되었다. 표피의 유리아미노산 함량은 대조군에 비해 변화하지 않았으며, 총 유리지방산 및 Stearic acid (C18:0), Palmitic acid (C16:0)의 함량은 감소하였다. 그러나 CJLP군에서 젖산의 함량은 대조군에 비해 12주차에 유의적으로 증가하였다. 즉 김치유산균 Lactobacillus plantarum 섭취는 CJLP 군에서 젖산 함량 증가와 함께 산도를 개선하였다.

• Journal of Ginseng Research
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• 제40권3호
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• pp.260-268
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• 2016

Background: During the aging process, skin shows visible changes, characterized by a loss of elasticity and the appearance of wrinkles due to reduced collagen production and decreased elasticity of elastin fibers. Panax ginseng Meyer has been used as a traditional medicine for various diseases due to its wide range of biological activities including skin protective effects. Ginsenosides are the main components responsible for the biological activities of ginseng. However, the protective activities of an enzymatic preparation of red ginseng against human skin aging have not been investigated. Methods: The efficacy of an enzyme-treated powder complex of red ginseng (BG11001) in preventing human skin aging was evaluated by oral administration to 78 randomized individuals. All patients were requested to take three daily capsules containing either 750 mg of BG11001 or a placebo vehicle for 24 wk; at the end of the testing period, skin roughness, elasticity, and skin water content were measured. Results: BG11001 significantly reduced the average roughness of eye wrinkles and the Global Photo Damage Score compared with the placebo, although there were no significant differences in arithmetic roughness average between the groups. In addition, gross elasticity and net elasticity values increased, and transepidermal water loss level decreased, indicating improved skin elasticity and moisture content. Conclusion: In conclusion, enzyme-treated red ginseng extract significantly improved eye wrinkle roughness, skin elasticity, and moisture content. Moreover, enzyme-treated red ginseng extract would be useful substance as a bio-health skin care product.