Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
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Dietary effect of Lactobacillus plantarum CJLP55 isolated from kimchi on skin pH and its related biomarker levels in adult subjects

김치유산균 Lactobacillus plantarum CJLP55 섭취가 성인 남녀의 피부 산도 및 관련 구성 인자의 변화에 미치는 영향

  • Han, Sangshin (Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University) ;
  • Shin, Jihye (Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University) ;
  • Lim, Sunhee (Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University) ;
  • Ahn, Hee Yoon (CJ Foods R&D Center, CJ CheilJedang Corporation) ;
  • Kim, Bongjoon (CJ Foods R&D Center, CJ CheilJedang Corporation) ;
  • Cho, Yunhi (Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University)
  • 한상신 (경희대학교 동서의학대학원 의학영양학과) ;
  • 신지혜 (경희대학교 동서의학대학원 의학영양학과) ;
  • 임선희 (경희대학교 동서의학대학원 의학영양학과) ;
  • 안희윤 (CJ제일제당 식품연구소 유용미생물팀) ;
  • 김봉준 (CJ제일제당 식품연구소 유용미생물팀) ;
  • 조윤희 (경희대학교 동서의학대학원 의학영양학과)
  • Received : 2018.12.10
  • Accepted : 2019.02.14
  • Published : 2019.04.30
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Abstract

Purpose: The skin pH is maintained by epidermal lactate, free fatty acids (FFAs), and free amino acids (FAAs). As a significant determinant of skin health, the skin pH is increased (less acidic) under abnormal and aged skin conditions. In a search for dietary alternatives that would promote an acidic skin pH, this study investigated the dietary effects of Lactobacillus plantarum CJLP55 isolated from Korean kimchi on the skin pH, and epidermal levels of lactate, FFAs, and FAAs in adult subjects. Methods: Seventy eight subjects (mean age $24.9{\pm}0.5years$, range 19 ~ 37 years) were assigned randomly to ingest CJLP55, Lactobacillus strain from kimchi, (n = 39, CJLP group) or placebo supplements (n = 39, placebo group) for 12 weeks in a double-blind, placebo-controlled trial. Skin pH and epidermal levels of lactate, FFAs and FFAs were assessed at 0, 6 and 12 weeks. Results: Although significant decreases in skin pH were observed in both the CJLP and placebo groups at 6 weeks, the skin pH was decreased significantly only in the CJLP group at 12 weeks. In parallel, the epidermal level of lactate in the CJLP group was also increased by 25.6% at 12 weeks. On the other hand, the epidermal level of FAAs were not altered in the CJLP and placebo groups, but the epidermal level of total FFAs, including palmitic acid and stearic acid, was lower in the CJLP group than in the placebo group over 12 weeks. The changes in the other FFAs, such as palmitoleic acid and oleic acid, were similar in the CJLP and placebo groups over 12 weeks. Conclusion: Overall, a dietary supplement of CJLP55 promotes acidic skin pH with a selective increase in epidermal lactate in adult subjects.

본 연구에서는 12주간 김치에서 추출한 유산균 Lactobacillus plantarum 섭취가 피부의 산도 및 관련인자인 유리아미노산, 젖산 및 유리지방산의 함량을 변화시키는지 파악하였다. CJLP 군에서 12주차에 피부 산도가 대조군에 비해 개선되었다. 표피의 유리아미노산 함량은 대조군에 비해 변화하지 않았으며, 총 유리지방산 및 Stearic acid (C18:0), Palmitic acid (C16:0)의 함량은 감소하였다. 그러나 CJLP군에서 젖산의 함량은 대조군에 비해 12주차에 유의적으로 증가하였다. 즉 김치유산균 Lactobacillus plantarum 섭취는 CJLP 군에서 젖산 함량 증가와 함께 산도를 개선하였다.

Keywords

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