• 제목/요약/키워드: Double-layered

검색결과 405건 처리시간 0.026초

Terfenadine-pseudoephedrine HCl의 이중정 및 유핵정의 비교 용출시험 (Comparative Dissolution test of Terfenadine-Pseudoephedrine HCl Double-layered and Core Tablet)

  • 최한곤
    • Journal of Pharmaceutical Investigation
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    • 제27권3호
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    • pp.213-217
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    • 1997
  • The present sustained-release terfenadine-pseudoephedrine HCl dosage form was the core tablet composed of outer (fast-release) layer containing 60 mg of terfenadine and l0mg of pseudoephedrine HCl, and inner (sustained-release) layer containing 110 mg of pseudoephedrine HCl. The purpose of this study was to investigate the possibility of formulating the terfenadine-pseudoephedrine HCl double-layered tablet which was bioequivalent to the core tablet. Its sustained-release and fast-release layer were formulated with disintegrating agents and polymers, respectively, varying with their kinds and amounts. The comparative dissolution test of double-layered and core tablet was carried out at pH 1.2, 4.0 and 6.8, leading to select composite of double-layered tablet whose dissolution pattern was similar to that of core tablet. It was composed of fast-release layer containing 60mg of terfenadine. 10 mg of pseudoephedrine HCl, sodium bicarbonate, microcrystalline cellulose and sodium starch glycolate, and sustained-release layer containing 110 mg of pseudoephedrine HCl and ethylcellulose/hydroxypropyl methylcellulose) (110/30 mg/tablet).

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전이금속 이중층 수산화물 기반 산소발생반응 촉매 연구 동향 (Transition Metal-Based Layered Double Hydroxides for Oxygen Evolution Reaction Catalysts)

  • 한다운;박경배
    • 한국전기전자재료학회논문지
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    • 제37권4호
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    • pp.358-373
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    • 2024
  • Oxygen evolution reaction is a critical bottleneck for the development of efficient electrochemical hydrogen production because of its sluggish reaction. Among various catalysts, transition metal-based layered double hydroxide has drawn significant attention due to their excellent catalytic properties and cost-effectiveness. This paper begins with basic crystal structures, and then conventional adsorbate evolution mechanism of layered double hydroxide. Strategies for enhancing catalytic properties based on adsorbate evolution mechanism and lattice oxygen mechanism that could surpass theoretical limit of adsorbate evolution mechanism are discussed. This paper ends with a brief discussion on the challenges and future directions of layered double hydroxide-based oxygen evolution reaction catalysts.

산화물 반도체 기반의 이종접합 광 검출기 (Metal Oxide-Based Heterojunction Broadband Photodetector)

  • 이상은;이경남;예상철;이성호;김준동
    • 한국전기전자재료학회논문지
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    • 제31권3호
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    • pp.165-170
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    • 2018
  • In this study, double-layered TCO (transparent conductive oxide) films were produced by depositing two distinct TCO materials: $SnO_2$ works as an n-type layer and ITO (indium-doped tin oxide) serves as a transparent conductor. Both transparent conductive oxide-films were sequentially deposited by sputtering. The electrical and optical properties of single-layered TCO films ($SnO_2$) and double-layered TCO ($ITO/SnO_2$) films were investigated. A TCO-embedding photodetector was realized through the formation of an $ITO/SnO_2/p-Si/Al$ layered structure. The remarkably high rectifying ratio of 400.64 was achieved with the double-layered TCO device, compared to 1.72 with the single-layered TCO device. This result was attributed to the enhanced electrical properties of the double-layered TCO device. With respect to the photoresponses, the photocurrent of the double-layered TCO photodetector was significantly improved: 1,500% of that of the single-layered TCO device. This study suggests that, due to the electrical and optical benefits, double-layered TCO films are effective for enhancing the photoresponses of TCO photodetectors. This provides a useful approach for the design of photoelectric devices, including solar cells and photosensors.

보온용 부직포의 구조적 특성이 열전달에 미치는 영향: 단층구조와 이층구조 부직포의 비교 (The Effect of Geometrical Structure on the Heat Transfer of Insulating Nonwovens: A Comparison of Single and Double Layered Nonwovens)

  • 김희숙
    • 한국생활과학회지
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    • 제7권2호
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    • pp.113-119
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    • 1998
  • The purpose of this study was to investigate the effect of geometrical structure on the heat transfer of insulating nonwovens. Commercially available single and double layered polyester nonwovens have used. Thermal conductivity, k and thermal conductance, h were measured by using a constant temperature sandwich type device at dry and wet state. The results obtained were as follows: 1. Double layered nonwovens showed slightly lower thermal conductance and higher warmability than single layered nonwovens. 2. As moisture regain increased, double layered nonwovens showed higher increasing rate of thermal conductivity than single layered nonwovens.

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Intercalation of Functional Organic Molecules with Pharmaceutical, Cosmeceutical and Nutraceutical Functions into Layered Double Hydroxides and Zinc Basic Salts

  • 황성호;한양수;최진호
    • Bulletin of the Korean Chemical Society
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    • 제22권9호
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    • pp.1019-1022
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    • 2001
  • Negatively charged functional organic molecules such as retinoic acid, ascorbic acid, indole acetic acid, citric acid, salicylic acid, acidic dye (indigo carmine, Food Blue 1) are intercalatively encapsulated by zinc basic salt (hydrozincite) and layered double hydroxide. Such functional organic-inorganic nanohybrids are realized via coprecipitation reaction involving simultaneous formation of layered inorganic lattice and intercalation of anionic species. The heterostructural nature of these nanohybrids, their particle morphology and textural characterizations are mainly discussed on the basis of Powder X-ray Diffraction and Field Emission Scanning Electron Microscopy results.

부직포 충전재의 구조적 특성이 수분전달 특성에 미치는 영향-단층구조와 이층구조 부직포의 비교- (The Effect of Geometrical Structure on the Moisture Transport Properties of Nonwoven Batting Materials)

  • 김희숙;나미희
    • 한국의류학회지
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    • 제24권6호
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    • pp.810-818
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    • 2000
  • The purpose of this study was to analyze the effect of geometrical structure on the moisture transport properties of nonwoven batting materials. Two types of nonwovens were used such as single and double layered nonwovens. Steady and dynamic state water vapor transport properties were measured by absorption, evaporation and cobaltous chloride method respectively. The results of this study were as follows: 1) Geometrical structure affected water vapor evaporation, but there were no differences between single and double layered nonwovens in moisture absorption. Thickness and air permeability were influencing factor on water vapor transport rate. 2) Directionality of double layered nonwoven was observed both in steady and dynamic state moisture transport. There were differences between upper and lower layer of double layered nonwoven both in moisture absorption rate and color change by cobaltous chloride method. 3) In dynamic state of water vapor transport rate, single layered nonwoven reached more rapidly at the established relative humidity. It was confirmed that geometrical structure affected water vapor evaporation and hydrophilicity of fiber affected moisture absorption because there were much more water vapor transport rate by evaporation than absorption within the same period of time.

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복층 및 다층장갑판재의 관통에 대한 상부경계이론 해석 (An upper bound analysis for the plugging type of ballistic perforation on the double and multi-layered armour plates)

  • 이종우
    • 한국군사과학기술학회지
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    • 제3권2호
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    • pp.35-41
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    • 2000
  • A modified theoretical analysis of the ballistic perforation on the double and multi-layered armour plates using an upper bound method has been presented in this paper. A modified model based on the suggestion of the Awerbuch-bodner model has been adapted and extended into double and multi-layered armour plates when the plugging type of penetration has been occurred. The residual projectile speed, ballistic limit velocity and contact time during the penetration process have been derived from the equation of motion at each stage.

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수열 합성 및 박리에 의한 Mg/Al 층상 이중 수산화물의 종횡비 제어 (Hydrothermal Synthesis and Exfoliation of Mg/Al Layered Double Hydroxide with Tailored Aspect Ratio)

  • 황성환;김동현;김예원;정현성
    • 한국전기전자재료학회논문지
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    • 제30권12호
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    • pp.822-827
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    • 2017
  • Mg/Al layered double hydroxide with two-dimensional (2D) nanostructures was synthesized by a hydrothermal technique. The morphology and aspect ratio of $Mg_4Al_2(OH)_{14}3H_2O$ were controlled by the concentration and kinds of the hydrolysis agent, and temperature. The aspect ratio of $Mg_4Al_2(OH)_{14}3H_2O$ layered double hydroxides with the 2D hexagonal crystal structure was tailored from about 12.6 to about 45.7. The intercalated $CO{_3}^{2-}$ anions of the synthesized 2D $Mg_4Al_2(OH)_{14}3H_2O$ layered double hydroxides were exchanged to $NO_3{^-}$ anions. The bulk 2D $Mg_4Al_2(OH)_{14}3H_2O$ layered double hydroxides with the increased space between two layers due to the anion exchange were exfoliated in a formamide solution. The aspect ratio of the exfoliated 2D $Mg_4Al_2(OH)_{14}3H_2O$ layered double hydroxides increased to 570.3.

O/W 용매 증발법을 이용한 PLGA와 덱스트란의 이중층 미립구 제조 (Fabrication of PLGA/Dextran Double-Layered Microspheres by Oil-in-Water Solvent Evaporation Method)

  • 고종태;이재호;이창래;신형식;육순홍;김문석;강길선;이종문;이해방
    • 폴리머
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    • 제29권6호
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    • pp.543-548
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    • 2005
  • 이중층 미립구는 단일층 미립구에 비해서 낮은 초기 방출량과 국소 지항성, 및 약물 방출량 제어 등의 장점 을 갖고 있다. 그러나 포접 방식이 까다롭고 2단계 이상의 제조 과정이 필요하며 특히 미립구 제조 시 크기 조절이 어렵다는 단점을 갖고 있다. 따라서 본 연구에서는 락타이드글리콜라이드 공중합체(PLGA)와 덱스트란의 서로 다른 고분자를 초고주파 분쇄 유무에 따른 수중유형(O/W) 용매 증발법을 이용하여 이중층 미립구를 제조하였다. 또한 PLGA의 농도에 따라 미립구 크기의 변화를 연구하였다. 이중층 미립구는 전자주사현미경, 동초점 형광 레이저현미경(CFLM), 캠스코프를 이용하여 조사하였다. 제조된 이중층 미립구의 외부층이 매끄러운 구형의 형태를 나타냄을 확인할 수 있었으며, 절단시 내부층과 외부층의 형태를 확실히 구분할 수 있었다. 이에 외부층과 내부층의 구성 물질을 확인하고자 플루오르신-5-이소시아네이트-덱스트란(FITC-덱스트란)을 이용해 CFLM을 관찰한 결과 형광을 띠는 덱스트란으로 구성된 내부층과 형광을 띠지 않는 PLGA 외부층을 관찰하였다. 또한 PLGA의 함량에 따른 미립구의 크기는 전체적으로 증가하는 경향을 확인하였다. 이와 같은 결과로부터 비교적 간단한 수중유형 용매 증발법을 이용하여 PLGA와 덱스트란의 이중층 미립구의 제조가 가능함을 확인할 수 있었다.

이중 및 삼중 로이창호의 일사획득에 따른 사무소건물의 냉난방에너지 성능분석 (Heating & Cooling Energy Performance Analysis of an Office Building according to SHGC level of the Double & Triple Glazing with Low-e Coating)

  • 김효중;박재성;신우철;윤종호
    • 한국태양에너지학회:학술대회논문집
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    • 한국태양에너지학회 2008년도 추계학술발표대회 논문집
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    • pp.90-95
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    • 2008
  • An SHGC(Solar Heat Gain Coefficient) is a determinant of total flux of solar radiation coming indoor and a critical factor in evaluating heating and cooling load. U-value represents heat loss while SHGC denominates heat gain. Recently, windows with high solar gain, mid solar gain or low solar gain are being produced with the development of Low-E coating technology. This study evaluated changes in energy consumption for heating and cooling according to changes in SHGC when using double-layered Low-E glass and triple layered Low-E glass in relation to double layered clear glass as base glass. An Office was chosen for the evaluation. For deriving optical properties of each window, WINDOW 5 by LBNL, an U.S. based company. and the results were analyzed to evaluate performance of heat and cooling energy on anannual basis using ESP-r, an energy interpretation program. Compared to the energy consumption of the double layered clear glass, the double layered Low-E glass with high solar gain consumed $69.5kWh/m^2,yr$, 9% more than the double layered clear glass in cooling energy. The one with mid solar gain consumed $63.1kWh/m^2,yr$, 1% less than the base glass while the one with low solar gain consumed $57.6kWh/m^2,yr$, 10% less than the base glass. When it comes to tripled layered glass, the ones with high solar showed 2% of increase respectively while the one with mid solar gain and low solar gain resulted 5% and 11% in decrease in energy consumption due to low acquisition of solar radiation. With respect to cooling energy. it was found that the lower the SHGC. the less energy consumption becomes.

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