• Title/Summary/Keyword: Double resonance

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High Resolution Time Resolved Contrast Enhanced MR Angiography Using k-t FOCUSS (k-t FOCUSS 알고리듬을 이용한 고분해능 4-D MR 혈관 조영 영상 기법)

  • Jung, Hong;Kim, Eung-Yeop;Ye, Jong-Chul
    • Investigative Magnetic Resonance Imaging
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    • v.14 no.1
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    • pp.10-20
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    • 2010
  • Purpose : Recently, the Recon Challenge at the 2009 ISMRM workshop on Data Sampling and Image Reconstruction at Sedona, Arizona was held to evaluate feasibility of highly accelerated acquisition of time resolved contrast enhanced MR angiography. This paper provides the step-by-step description of the winning results of k-t FOCUSS in this competition. Materials and Methods : In previous works, we proved that k-t FOCUSS algorithm successfully solves the compressed sensing problem even for less sparse cardiac cine applications. Therefore, using k-t FOCUSS, very accurate time resolved contrast enhanced MR angiography can be reconstructed. Accelerated radial trajectory data were synthetized from X-ray cerebral angiography images and provided by the organizing committee, and radiologists double blindly evaluated each reconstruction result with respect to the ground-truth data. Results : The reconstructed results at various acceleration factors demonstrate that each components of compressed sensing, such as sparsifying transform and incoherent sampling patterns, etc can have profound effects on the final reconstruction results. Conclusion : From reconstructed results, we see that the compressed sensing dynamic MR imaging algorithm, k-t FOCUSS enables high resolution time resolved contrast enhanced MR angiography.

Ridge-Loaded Small Round-Ended Slot for Waveguide Slot-Array Antenna (도파관 슬롯 배열 안테나용 리지가 장하된 끝이 둥근 소형 슬롯)

  • Kim, Byung-Mun;Lee, Jong-Ig;Cho, Young-Ki
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.23 no.8
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    • pp.950-957
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    • 2012
  • In this paper, a small round-ended slot loaded by double ridges on the broad wall of a rectangular waveguide is presented as an element for a waveguide slot-array antenna(WSAA). By properly adjusting the ridge dimension, a resonance of the slot at a desired frequency can be achieved. The resonant length of the proposed slot is about $0.26{\lambda}_0$(free space wave length) at the resonance frequency. The proposed resonant slot has some advantageous properties, such as small size, small resonant conductance, and short and stable resonant slot length. In addition, the characteristics of the slots are slightly affected by the adjacent elements when the slots are arrayed for a waveguide slot antenna. A $4{\times}1$ WSAA with -20 dB side-lobe level(SLL) is designed, fabricated, and tested experimentally. The measured results are well agreed with the simulated ones and have an SLL of -15.9 dB and a half-power beam width of $110.2^{\circ}$ in the E-plane and $21.2^{\circ}$ in the H-plane, respectively, at 9.41 GHz.

Characterization of Layered Double Hydroxides(Mg-Al-$CO_3$ systems) and Rehydration Reaction of Their Calcined Products in Aqueous Chromate Solution (층상이중수산화물(Mg-Al-$CO_3$ 체계)의 물리 · 화학적 특성규명 및 소성된 시료의 크롬산이온 수용액에서 재수화반응)

  • Rhee, Seog Woo;Kang, Mun-Ja;Moon, Hichung
    • Journal of the Korean Chemical Society
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    • v.39 no.8
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    • pp.627-634
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    • 1995
  • Layered double hydroxides ($Mg-Al-CO_3$ systems, LDH), which are hydrotalcite-like anionic clay minerals, having different $Mg^{2+}\;to\;Al^{3+}$ ratio were synthesized by coprecipitation method. The subsequent products were characterized by the following methods; elemental analysis, X-ray powder diffraction, thermal analysis (DSC and TGA), FT-IR and $^{27}$Al-MAS NMR. X-ray powder patterns showed that the products formed were layered structure materials. Two heat absorption peaks were observed around 20 ∼280$^{\circ}C$ (surface water and interlayer water) and 280∼500$^{\circ}C$ (water from lattice hydroxide and carbon dioxide from interlayer carbonate) in DSC diagrams, and they were quantitatively analyzed by TGA diagrams (in case LDH4 16.2% and 28.6% respectively). FT-IR spectra indicate that the interlayer carbonate ions occupied symmetrical sites between two adjacent layers in a parallel direction. $^{27}$Al-MAS NMR spectra show only single resonance (8.6 ppm) of the octahedrally coordinated aluminum similar magnesium. When LDH4 was calcined at 560$^{\circ}C$ for 3 hours in air, its layered structure was destroyed giving a mixed metal oxide. However it readily became rehydrated in aqueous chromate solution to its original structure.

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BS/channeling studies on the heteroepitaxially grown $Y_2O_3$ films on Si substrates by UHV-ICB deposition (실리콘 기판 위에 UHV-ICB 증착법으로 적층 성장된 $Y_2O_3$박막의 BS/channeling 연구)

  • 김효배;조만호;황보상우;최성창;최원국;오정아;송종한;황정남
    • Journal of the Korean Vacuum Society
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    • v.6 no.3
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    • pp.235-241
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    • 1997
  • The crystallinity and the structure of heteroepitaxially grown $Y_2O_3$ films on the silicon substrates deposited by Ultra High Vacuum Ionized Cluster Beam(UHV-ICB) were investigated by Back-scattering Spectroscopy(BS)/channeling. The channeling minimum values, $X_{min}$, of the $Y_2O_3$ films deposited by other methods were 0.8~0.95 up to the present, which indicates amorphous or highly polycrystalline nature of the $Y_2O_3$ films. On the contrary, the channeling minimum value of heteroepitaxially grown $Y_2O_3$ films on Si(100) and Si(111) deposited by UHV-ICB are 0.28 and 0.25 respectively. These results point out fairly good crystalline quality. It is also observed that the top region of $Y_2O_3$ films have less crystalline defects than the bottom region regardless of the crystal direction of the Si substrates. The axis of $Y_2O_3$<111> epitaxially grown on Si(111) is tilt by $0.1^{\circ}$ with respect to Si<111>. That of $Y_2O_3$<110> on Si(100) is parallel to the Si<001>. The $Y_2O_3$ film on Si(100) grew with single domain structure and that on Si(111) grew with double domain structure. From the result of oxygen resonance BS/channeling, the oxygen atoms in heteroepitaxially grown $Y_2O_3$ film on Si(111) substrate have the crystallinity, but that on Si(100) shows almost channeling amorphous state.

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Design of a Double-Faced Monopole Antenna Using the Coupling Effect of Induced Currents (유도 전류의 커플링 효과를 이용한 모노폴 안테나 설계)

  • Choi, Young;Lee, Seungwoo;Kim, Nam
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.23 no.12
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    • pp.1327-1336
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    • 2012
  • In this paper, the dual-faced monopole antenna, which is arranged by numerous rectangular ring patches in sequence for the multi-bands is proposed. The ring type structure of the patch can be increased the bandwidth. Therefore the bandwidth and beam width are improved by using multiple arrayed patches. When the ring type patches are inserted serially, the resonance frequencies are occurred by the current flow from the first ring patch. It is possible because the gap between the patches is very narrow. In addition, if the patches are composed on the same plane as the feed-line, fabrication could be very difficult because the gap between the patches is extremely narrow. The thickness and permittivity of the antenna, moreover, are very important parameters because both sides of the substrate are used. We finally found the optimal thickness and permittivity to generate the coupling effect by simulation. All patches are consisted of 4-steps which the patch size was decreased 85 % by each step. In conclusion, the resonant frequency bands are 1.75~2.6 GHz(850 MHz), 3.24~3.46 GHz(220 MHz), 3.8~4.0 GHz(200 MHz), and 4.4~4.9 GHz(500 MHz).

Scalable Inductor Modeling for $0.13{\mu}m$ RF CMOS Technology ($0.13{\mu}m$ RF CMOS 공정용 스케일러블 인덕터 모델링)

  • Kim, Seong-Kyun;Ahn, Sung-Joon;Kim, Byung-Sung
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.46 no.1
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    • pp.94-101
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    • 2009
  • This paper presents scalable modeling of spiral inductors for RFIC design based on $0.13{\mu}m$ RF CMOS process. For scalable modeling, several inductor patterns are designed and fabricated with variations of width, number of turns and inner radius. Feeding structures are optimized for accurate de-embedding of pad effects. After measuring the S parameters of the fabricated patterns, double-$\pi$ equivalent circuit parameters are extracted for each device and their geometrical dependences are modeled as scalable functions. The inductor library provides two types of models including standard and symmetric inductors. Standard and symmetric inductors have the range of $0.12{\sim}10.7nH$ and $0.08{\sim}13.6nH$ respectively. The models are valid up to 30GHz or self-resonance frequency. Through this research, a scalable inductor library with an error rate below 10% is developed for $0.13{\mu}m$ RF CMOS process.

Design and Fabrication of Dual-Band Patch Antenna with Bridge for WLAN Applications (WLAN용 이중대역 브리지 패치 안테나설계 및 제작)

  • Kim, Kab-Ki
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.14 no.3
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    • pp.547-551
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    • 2010
  • In this paper, Double rectangular patch with 4-bridges is investigated for solution of IEEE 802.11b/g(2.4GHz) and 802.11a(5.7GHz). Rectangular patch for 5.7GHz frequency band is printed on the PCB substrate and connected to another rectangular patch for 2.4GHz frequency band with 4-bridges to obtain dual band operation in a antenna element. The proposed antenna has a low profile and is fed by $50{\Omega}$ coaxial line. The dielectric constant of the designed antenna substrate is 3.27. Two rectangular patches have each resonance frequencies that are 2.4GHz and 5.7GHz. A dual-band characteristic is shown as connecting two rectangular patch using four bridges. Also, the proposed antenna is shown input return loss that is below -10dB at 2.4GHz and 5.7GHz of WLAN(Wireless LAN).

Targeting HSP90 Gene Expression with 17-DMAG Nanoparticles in Breast Cancer Cells

  • Mellatyar, Hassan;Talaei, Sona;Nejati-Koshki, Kazem;Akbarzadeh, Abolfazl
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.5
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    • pp.2453-2457
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    • 2016
  • Background: Dysregulation of HSP90 gene expression is known to take place in breast cancer. Here we used D,L-lactic-co-glycolic acid-polyethylene glycol-17-dimethylaminoethylamino-17-demethoxy geldanamycin (PLGA-PEG-17DMAG) complexes and free 17-DMAG to inhibit the expression of HSP90 gene in the T47D breast cancer cell line. The purpose was to determine whether nanoencapsulating 17DMAG improves the anti-cancer effects as compared to free 17DMAG. Materials and Methods: The T47D breast cancer cell line was grown in RPMI 1640 supplemented with 10% FBS. Encapsulation of 17DMAG was conducted through a double emulsion method and properties of copolymers were characterized by Fourier transform infrared spectroscopy and H nuclear magnetic resonance spectroscopy. Assessment of drug cytotoxicity was by MTT assay. After treatment of T47D cells with a given amount of drug, RNA was extracted and cDNA was synthesized. In order to assess HSP90 gene expression, real-time PCR was performed. Results: Taking into account drug load, IC50 was significant decreased in nanocapsulated 17DMAG in comparison with free 17DMAG. This finding was associated with decrease of HSP90 gene expression. Conclusions: PLGA-PEG-17DMAG complexes can be more effective than free 17DMAG in down-regulating of HSP90 expression, at the saesm time exerting more potent cytotoxic effects. Therefore, PLGA-PEG could be a superior carrier for this type of hydrophobic agent.

A Design of Electronic Ballast for 70W Metal Halide Lamps (70W 메탈핼라이드용 전자식 안정기의 설계)

  • 최명호;임성훈;한병성
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.13 no.3
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    • pp.7-13
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    • 1999
  • In this paper, a low wattage high frequency operation electronic ballast for double ended 70W metal halide lamp has been investigated As an input source of the proposed ballast, 220V, 60 Hz ac voltage is used and is converted high frequency ac voltage by power processing system. To prevent a physical destruction of the lamp from acoustic resonance phenorrenon, the proposed ballast sLWlies alternating voltage of 22kHz frequency to a metal halide lamp. It shows sorre efficacious result that reduce the start up tiIre of lamp and electric power consumption. By testing the proposed ballast, lamp voltage and lamp current are 155Vpeak, O.64A, respectively. Lamp luminous flux is 5300lm with 82W input power and ballast efficiency is 64.63 Im/w. The average starting tiIre and restriking tiIre of lamp are 3.9 and 4.5 minutes, respectively.tively.

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The Wormicidal Substance of Fresh Water Fishes on Clonorehis sinensis V. Purification and Chemical Charaeterization of Clonorehicidal Substance from Epidermal Mucus of Cyprinus carpio (간흡충에 대한 살충성 물질에 관한 연구 V. 잉어 체표점액내 살충성물질의 화학적 성상)

  • 이재구;안병준
    • Parasites, Hosts and Diseases
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    • v.22 no.1
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    • pp.127-134
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    • 1984
  • As a series of studies to clarify clonorchicidal substances in body surface mucus of some freshwater fishes, the substance in the epidermal mucus of Cyprinus carpio was isolated by silica gel column and thin layer chromatography and analysed for its chemical nature. Wormicidal trial was done in vitro, and the results obtained are summarized as follows: The mucus was extracted by ethyl ether and separated into 4 fractions by column chromatography using benzene as solvent. The second fraction with yellowish red colour among them showed the strongest clonorchicidal effect. The yellowish red fraction obtained by column chromatography was then fractionated into 6 spots by thin layer chromatography with petrol/ etherjchloroform (30/70, v/v), and the Rf. 0.714 spot among the 6 spots showed the strongest effect. The Rf. 0.714 spot was further fractionated into 6 spots by thin layer chromatography with benzene/acetone (90/10, vlv), and the Rf. 0.800 spot among the later 6 spots revealed the strongest effect. The Rf. 0.800 spot was chromatographed on column with benzene and 2 fractions were obtained. The second fraction of light brown colour represented the final purified fraction. By these Purification Procedures, clonorchicidal substance was Purified 15-fold with 0.035 yield from the mucus of C. carpio, and 10mg of the final fraction killed the cercaria in 26 min, the metacercaria in 115 min, and the adult in 443 min. Infra red and nuclear magnetic resonance spectrometric analysis of the purified substance revealed that the substance belongs to an ethyl ester of unsaturated fatty acid with 2 double bonds, 15 methylene groups and 1 methyl group.

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