• Title/Summary/Keyword: Dose-rate

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Dose Distribution of Wedge filter by Dose Rate in LINAC (선형가속기의 선량율에 따른 쐐기필터의 선량분포)

  • Gwon, Taehyeong;Kim, Seunguk;Yoon, Yonghak;Won, Doyeon;Jeong, Kyeonghwan;Jung, Jaeeun;Cho, Juneho
    • Journal of the Korean Society of Radiology
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    • v.9 no.5
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    • pp.323-329
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    • 2015
  • This study is aimed at assessing whether dynamic wedge filters are appropriate to be used instead of physical wedge filters. The X-ray energy generated from linear accelerator is commercialize 6 MV and 10 MV. $15^{\circ}$, $30^{\circ}$, $45^{\circ}$, and $60^{\circ}$ of physical wedge filter was irradiated by dose rate 100, 200, 300, 400, 500, and 600 MU/min for each angle and for comparison with a dynamic wedge filter, irradiate 96 times under the same conditions. The measurement conditions are as 100 cm source-film distance and $10{\times}10cm$ irradiated surface. A developed film was scanned and analyzed after a calibration through a dose analysis program and the dose rate was compared after calculating the standard deviation. Dynamic wedge filters make dose, scattered rays and treatment time reduced and very useful due to less irradiated doses to patients. The errors at each dose rate under the same conditions were irrelevant. Thus, treatment based on a high dose rate depending on the patient is expected to be feasible.

Effects of Gamma-ray Irradiation on Growth Characteristics and DNA Damage in Licorice (Glycyrrhiza uralensis) (감마선 조사가 감초(Glycyrrhiza uralensis)의 초기 생육 및 DNA 손상에 미치는 영향)

  • Ryu, Jaihyunk;Im, Seung Bin;Kim, Dong Sub;Ahn, Joon-Woo;Kim, Jin-Baek;Kim, Sang Hoon;Kang, Si-Yong
    • Journal of Radiation Industry
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    • v.8 no.2
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    • pp.89-95
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    • 2014
  • This study was conducted to determine the optimal dose of gamma-ray on the growth and nucleus DNA damage for mutation breeding in licorice. Gamma-rays irradiated to dry seeds with various doses (0 to 1000 Gy). Significant decreases in germination rate (%), survival rate (%) and growth characteristics (plant height, number of leaves, root length and fresh weight) were observed by dose of increased. $LD_{50}$ (lethal dose) was approximately 400 Gy to 500 Gy. Also, reduction doses ($RD_{50}$) of plant height, number of leaves, root length and flash weight were 428 Gy, 760 Gy, 363 Gy and 334 Gy, respectively. It is supplest that the optimal dose of gamma irradiation for licorice mutation induction might be about 400 Gy in this study. We also conducted comet assay to observe nucleus DNA damage due to gamma irradiation. In comet assay, a clear difference was identified over 300 Gy treatments. With increasing doses of gamma-ray in the range of 100 to 1000 Gy, the rate of head DNA was decreased significantly from 92.88% to 73.09%. Tail length(${\mu}m$) was increased as the dose of increased over 300 Gy. Growth characteristics (Germination rate, Survival rate, plant height, number of leaves, root length and fresh weight) were highly negatively ($P{\leq}0.01$) correlated with dose. While the tail length was highly positively ($P{\leq}0.01$) correlated with dose.

Evaluation of Caregivers' Exposed Dose and Patients' External Dose Rate for Radioactive Iodine (I-131) Therapy Administration in Isolated Ward (방사성요오드(I-131) 격리병실 치료 관리를 위한 환자의 체외방사선량률과 상주 보호자의 피폭선량평가)

  • Kang, Seok-Jin;Lee, Doo-Hyeon;So, Young;Lee, Jeong-Woo
    • Journal of radiological science and technology
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    • v.45 no.4
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    • pp.347-353
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    • 2022
  • In this study, the radiation dose rate was measured by time and distance and evaluated whether radiation dose rate was suitable for domestic and international discharge criteria. In addition, the radiation dose emitted from the patient was measured with a glass dosimeter to evaluate the exposure dose if the caregiver stays in the isolated ward by placing a humanoid phantom instead of the caregiver at a distance of 1 m from the patient, on the second day of treatment. After 23 hours of isolation, the radiation dose rates at a distance of 1 m were 20.54 ± 6.21 µSv/h at 2.96 GBq administration and 27.94 ± 12.33 µSv/h at 3.70 GBq administration. The radiation dose rates at a distance of 1 m were 25.90 ± 2.21 µSv/h when 2.96 GBq was administered and 34.22 ± 10.06 µSv/h when 3.70 GBq was administered after 18 hours of isolation. However, if the isolation period is short may cause unnecessary radiation exposure to the third person. The reading of the attached dosimeter from the morning of the second day of treatment until removal was 0.01 to 0.95 mSv, which is a surface dose determined by the International Commission on Radiation Units and Measurements. And the depth dose was 0.01 to 0.99 mSv. On the second day of treatment, even if the patient caregivers stayed in the isolation ward, the exposure dose of the patient family did not exceed the effective dose limit of 5 mSv recommended by the ICRP and NCRP.

정액의 희석배율 및 주입 정자수가 닭의 수정능력에 미치는 영향

  • 김학규;나재천;최철환;장병귀;상병돈;이상진
    • Proceedings of the Korea Society of Poultry Science Conference
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    • 2002.11a
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    • pp.116-117
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    • 2002
  • This study was conducted to investigate the effects of dilution rate and stored time of semen at 5, 25 and 35$^{\circ}C$ on mobility in liquid rooster semen. At 5$^{\circ}C$ cold temperature, no significant difference were found in sperm mobilities on dilution rate and stored time among treatments stored at 5$^{\circ}C$. Sperm mobility for the conservation of 1 hours at 25$^{\circ}C$ and 3 hours at 35$^{\circ}C$ were significantly higher for 1:2 and 1:3 dilution rate(semen: diluent) groups than for 1:1 dilution rate group(P〈0.05), In Fertility results after artificial insemination with different number of sperm per dole, fertilization rate of liquid rooster semen diluted with skim milk-glucose solution were 90.67, 94.00, 96.00, and 98.67% for 0.2${\times}$10$\^$8//dose, 0.4${\times}$10$\^$8//dose, 1.0${\times}$10$\^$8//dose, and 2.0${\times}$10$\^$8//dose groups, respectively. To have more than 90% fertility, 0.2${\times}$10$\^$8/ sperm per dose for the artificial insemination (AI) could be used, And to have more 94% fertility, 0.4${\times}$10$\^$8/ sperm per dose AI could be used practically.

Determination of Thyroid Secretion Rate in Rabbit (토끼의 갑상선 측정)

  • 이종진;윤세중
    • The Korean Journal of Zoology
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    • v.3 no.1
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    • pp.19-23
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    • 1960
  • A method for determination of thyroid secretion rate in rabbit by means of radioactive iodine presented. After injection of radioactive iodine, in vivo determination so f radioactivity in thyroid gland were made during a 19 day-experimental period. In the same period blood samples were drawn and analyzed for protein-bound iodine (PBI) and for protein-bound radioactive iodine(PBI181). A rate constant for secretion of thyroid hormone was calculated from the disappearance rate of radioactive iodine in thyroid gland. The secretion rate of radioactive hormone iodine was calculated by multiplying this rate constant by the amount of radioactive iodine present in thyroid gland. Assuming that the specific radioactiveness of the circulating thyroid hormone and of the hormone just secreted were identical , thyroid secretion rate was calculated by the equation. {{{{ { Secreted hormone-iodine , gamma /hr} over { Secreted hormone-I^131, % dose/hr }= { PBI, ${\gamma}$/ml.Serum} over { PBI^131 , % dose/ml . Serum } }} The method presented consisted of measurements for series of independent criteria on thyroid function, and the resulting thyroid secretion rate was calculated by combination of those.

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Nonparametric Procedures for Finding the Minimum Effective Dose in Each of Several Group (다중 그룹 상황에서의 최소 효과 용량을 정하는 비모수적 검정법)

  • Bae, Su-Hyun;Kim, Dong-Jae
    • Communications for Statistical Applications and Methods
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    • v.19 no.1
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    • pp.33-45
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    • 2012
  • The primary interest of drug development studies is to estimate the smallest dose that shows a significant difference from the zero-dose control. The smallest dose is called the Minimum Effective dose(MED). In this paper, we suggest a nonparametric procedure to simultaneously find the MED of each group based on placements. The Monte Carlo simulation is adapted to estimate the power and the family-wise error rate(FWE) of the new procedures with those of discussed nonparametric tests to find MED.

Real-time monitoring of ultra-high dose rate electron beams using bremsstrahlung photons

  • Hyun Kim;Dong Hyeok Jeong;Sang Koo Kang;Manwoo Lee;Heuijin Lim;Sang Jin Lee;Kyoung Won Jang
    • Nuclear Engineering and Technology
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    • v.55 no.9
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    • pp.3417-3422
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    • 2023
  • Recently, as the clinically positive biological effects of ultra-high dose rate (UHDR) radiation beams have been revealed, interest in flash radiation therapy has increased. Generally, FLASH preclinical experiments are performed using UHDR electron beams generated by linear accelerators. Real-time monitoring of UHDR beams is required to deliver the correct dose to a sample. However, it is difficult to use typical transmission-type ionization chambers for primary beam monitoring because there is no suitable electrometer capable of reading high pulsed currents, and collection efficiency is drastically reduced in pulsed radiation beams with ultra-high doses. In this study, a monitoring method using bremsstrahlung photons generated by irradiation devices and a water phantom was proposed. Charges collected in an ionization chamber located at the back of a water phantom were analyzed using the bremsstrahlung tail on electron depth dose curves obtained using radiochromic films. The dose conversion factor for converting a monitored charge into a delivered dose was determined analytically for the Advanced Markus® chamber and compared with experimentally determined values. It is anticipated that the method proposed in this study can be useful for monitoring sample doses in UHDR electron beam irradiation.

Measurement of the Spatial Scattering Dose by Opening, Closing Door and Installing Shielding : A Study on the Reduction of Exposure Dose in Radiography (문 개폐 여부와 차폐체 설치 유무에 따른 공간산란선량 측정 : X선 촬영 시 피폭선량 감소방안에 대한 연구)

  • Yoon, Hong-Joo;Lee, Yong-Ki;Lee, In-Ja
    • Journal of radiological science and technology
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    • v.42 no.6
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    • pp.477-482
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    • 2019
  • Recently, due to the increased use of medical radiation, the radiation exposure of radiation workers should be considered as well as medical exposure of patients. And it is recommended to close the door during radiography. however, In this study, when the door was inevitably opened for radiography, the proposed method was to install the shield as a method of reducing the exposure dose. And its efficiency was analyzed. In simple chest radiography, the measurement point was changed according to the measurement location. Dose rate were measured 10 times for each condition using a dosimeter. And the average value was derived. Using this, the change of dose according to the opening and closing of the door and the installation of the shield was analyzed. Using this, we compared and analyzed the dose change according to the door opening and closing and the installation of the shield, and significance was verified through the SPSS ver. 24. Depending on whether the door was opened or closed, 11,215.35%, 159.0%, 101.9% increased in front of the door in the consol room, behind the wall and behind the lead glass. Depending on the installing of the shield, the 49.2%, 29.6%, 19.9%, 30.6% decrease in front of the door in the examination and consol room, behind the wall and lead glass. In addition, statistical analysis was showed that there were significant differences in both the results according to whether the door was opened or closed and shielding(p<.05). Close the door during radiography. However, when the door should be opened, it was confirmed that the dose rate were reduced by installing the shield. Therefore, to optimize radiation protection, it is recommended to install shields when opening the door.

BENCHMARK CALCULATION OF CANDU END SHIELDING SYSTEM

  • Gyuhong Roh;Park, Hangbok
    • Proceedings of the Korean Nuclear Society Conference
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    • 1998.05b
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    • pp.618-623
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    • 1998
  • A shielding analysis was performed for the end shield of CANDU 6 reactor. The one-dimensional discrete ordinate code ANISN with a 38-group neutron-gamma library, extracted from DLC-37D library, was used to estimate the dose rate for the natural uranium CANDU reactor. For comparison MCNP-4B calculation was performed for the same system using continuous, discrete and multi-group libraries. The comparison has shown that the total dose rate of the ANISN calculation agrees well with that of the MCNP calculation. However, the individual dose rate (neutron and gamma) has shown opposite trends between AMISN and MCNP estimates, which may require a consistent library generation for both codes.

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Distribution and characteristics of radioactivity$(^{232}Th,\;^{226}Ra,\;^{40}K,\;^{137}Cs\;and\;^{90}Sr)$ and radiation in Korea

  • Yun, Ju-Yong;Choi, Seok-Won;Kim, Chang-Kyu;Moon, Jong-Yi;Rho, Byung-Hwan
    • Journal of Radiation Protection and Research
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    • v.30 no.4
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    • pp.167-174
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    • 2005
  • The concentrations of natural and artificial radionuclides in soil and gamma ray dose rate in air at 233 locations in Korea have been determined. The national mean concentrations of $^{232}Th,\;^{226}Ra,\;^{40}K,\;^{137}Cs\;and\;^{90}Sr$ in soil were $60{\pm}31,\;33{\pm}14,\;673{\pm}238,\;35{\pm}9.3\;and\;5.0{\pm}3.4\;Bq\;kg^{-1}$, respectively. The mean gamma-ray dose rate at 1 m above the ground was $7918\;nGy\;h^{-1}$. $^{137}Cs$ concentration had highly significant correlation with organic matter content and cation exchange capacity. $^{90}Sr$ concentration had slightly coherent with pH. The results have been compared with other global radioactivity and radiation measurements.