• 제목/요약/키워드: Dose optimization

검색결과 231건 처리시간 0.03초

Evaluation of auto contouring accuracy in 3D planning system (3차원 입체조형치료시 Auto Contouring tool의 유용성 평가)

  • Choi, JM;Ju, SG;Park, JY;Park, YH;Kim, JS
    • The Journal of Korean Society for Radiation Therapy
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    • 제14권1호
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    • pp.35-39
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    • 2002
  • Introduction : It is essential to input patients external contour in 3D treatment plan. We would like to see changes in depth and dose when 3D RTP is operating auto contouring when windows value (Width/Level) differs in this process. Material & Methode : We have analyzed the results with 3D RTP after CT Scanning with round CT Phantom. We have compared and analyzed MU values according to depth changes to Isocenter changing external contour and inputting random Window value. We have watched change values according to dose optimization in 4 directions(LAO, LPO, RAO, RPO), We plan 100 case for exact analyzation. We have results changing window value random to each beam in 100 cans. Result : It showed change between minimum and maximum value in 4 beam is Depth 0.26mm, MU $1.2\%$ in LAO. It showed LPO-Depth 0.13mm, MU $0.9\%$, RAO-Depth 0.2mm MU $0.8\%$, RPO-Depth 0.27mm, MU $1.1\%$ Conclusion : Maximum change in depth 0.27 mm, MU error rate is $0.12\%$ according to Window change. As we can see in these results, it seems Window value change doesn't effect in treatment. However, it seems there needs to select appropriate Window value in precise treatment.

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Application of Response Surface Method as an Experimental Design to Optimize Coagulation Tests

  • Trinh, Thuy Khanh;Kang, Lim-Seok
    • Environmental Engineering Research
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    • 제15권2호
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    • pp.63-70
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    • 2010
  • In this study, the response surface method and experimental design were applied as an alternative to conventional methods for the optimization of coagulation tests. A central composite design, with 4 axial points, 4 factorial points and 5 replicates at the center point were used to build a model for predicting and optimizing the coagulation process. Mathematical model equations were derived by computer simulation programming with a least squares method using the Minitab 15 software. In these equations, the removal efficiencies of turbidity and total organic carbon (TOC) were expressed as second-order functions of two factors, such as alum dose and coagulation pH. Statistical checks (ANOVA table, $R^2$ and $R^2_{adj}$ value, model lack of fit test, and p value) indicated that the model was adequate for representing the experimental data. The p values showed that the quadratic effects of alum dose and coagulation pH were highly significant. In other words, these two factors had an important impact on the turbidity and TOC of treated water. To gain a better understanding of the two variables for optimal coagulation performance, the model was presented as both 3-D response surface and 2-D contour graphs. As a compromise for the simultaneously removal of maximum amounts of 92.5% turbidity and 39.5% TOC, the optimum conditions were found with 44 mg/L alum at pH 7.6. The predicted response from the model showed close agreement with the experimental data ($R^2$ values of 90.63% and 91.43% for turbidity removal and TOC removal, respectively), which demonstrates the effectiveness of this approach in achieving good predictions, while minimizing the number of experiments required.

Optimization of Coagulation and Media Filtration Process for Low Turbidity Seawater (저탁도 해수원수 특성에 적합한 응집 - 여과 공정의 최적화)

  • Son, Dong-Min;Jo, Myeong-Heum;Kim, Jeong-Sook;Kang, Lim-Seok
    • Journal of Korean Society of Environmental Engineers
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    • 제36권4호
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    • pp.251-257
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    • 2014
  • This research is focused on coagulation and sand filtration process as a pretreatment of RO seawater desalination. RO systems require sufficient and reliable pretreatment process to produce superior quality of RO feedwater that can mitigate RO membrane fouling. This experiment was conducted to investigate the effectiveness of coagulation and filtration process under various experimental conditions including different coagulant dose, flocculation mixing intensity and time, turbidity, and filtration rate. The experimental results showed that the optimum pretreatment conditions resulting in lower SDI value suitable for RO feedwater were coagulation pH 6.5, raw water turbidity greater than 4 NTU, and media bed depth greater than 550 mm. However, flocculation mixing intensity, coagulant dose, and filtration rate relatively affected little on the filtration efficiency.

중수로 환형기체 계통의 방사능 inventory 평가

  • Kim, Jin-Tae;Kang, Deok-Won;Son, Uk
    • Proceedings of the Korean Radioactive Waste Society Conference
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    • 한국방사성폐기물학회 2003년도 가을 학술논문집
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    • pp.90-95
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    • 2003
  • Chemical management of annulus gas system is carried out for the purpose of ensuring the safety and reliability of the system via securing the integrity of the system, detecting the D$_2$O in-leakage of coolant and/or moderator, and reducing the radiation dose. Since the quality of CO_2$ gas, which is used as a filling gas for annulus gas system at CANDU plants, has a propound effect on the integrity of the system material and the radiation dose, CO_2$ gas of high quality is needed. If the quality of CO_2$ gas does not meet the specification, it may give rise to undesirable effect not only on the annulus gas system, but also on the environment due to the production of radioactive nuclei. Therefore, it is very important to check the impurities of CO_2$ gas. Based on this background, the inventories of C-14 and Ar-41 in CO_2$ gas that is supplied as annulus gas were estimated using the data on concentrations of the impurities of $CO_2$ such as C, N_2$ and Ar. The results of this study is expect to give useful information on optimization of CO_2$ impurities maintenance and management of gaseous radioactive wastes produced at CANDU plants.

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Effects of Propolis on Tumoricidal Activities (Propolis가 종양 억제작용에 미치는 영향)

  • Kwon Myung-Sang;Kim Young-Hwu;Cho Jung-Soon
    • Journal of the East Asian Society of Dietary Life
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    • 제15권5
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    • pp.542-548
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    • 2005
  • In recent years, propolis has attracted much attention as an useful substance in medicine and functional food, even if it is known as a natural remedy in folk medicine since ancient times. propolis was registered as natural food since 1995 on Korean Food Act by Korean Food and Drug Administration(KFDA). The present study demonstrated the optimization of isolation of crude propolis by ethanol, and tumoricidal effect of pro polis. The optimal concentration of ethanol to separate a high quantity of propolis was $60\%$. The cytotoxic effect of ethanol extracted propolis against various cancer cell lines including murine lymphoma (Sarcoma-180), murine T-lymphoma (YAC-1), human breast carcinoma (MCF-7), human gastric carcinoma (KATOIII) and human hepatocellular carcinoma (Hep3B) and human lung adenocarcinoma (A-549) was observed using SRB and MIT assay. In order to investigate the curative activity by oral administration of propolis on tumor, ICR mice was subcutaneously implanted Sarcoma 180. In 300mg/kg and 600mg/kg propolis administered group, development of implanted tumors was inhibited by $40.9\%\;and\;67.9\%$ at 16th day, respectively. In the same dose of propolis administered group, development of implanted tumors was inhibited more strongly with dose dependent manner. Therefore, these data suggested propolis may show tumoricidal effects. In conclusion, these results indicate that propolis, one of the few natural remedies, can be used as functional food with tumoricidal effects.

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Risk Management on Radiation under Prolonged Exposure Situation - Focusing on the Tokyo Metropolitan Area in Japan Under the TEPCO Fukushima Dai-ich NPP Accident -

  • Iimoto, Takeshi;Hayashi, Rumiko;Kuroda, Reiko;Furusawa, Mami;Umekage, Tadashi;Ohkubo, Yasushi;Takahashi, Hiroyuki;Nakamura, Takashi
    • International Journal of Safety
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    • 제10권2호
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    • pp.6-9
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    • 2011
  • Examples and experiences of risk management on radiation under prolonged exposure situation are shown. The accident of the Fukushima dai-ichi nuclear power plant after the great east Japan earthquake (11 March, 2011) elevates background level of environmental radiation around the east Japan. For example, ambient dose equivalent rate around Tohkatsu area next to Tokyo located about 200 km-south from the plant, is about 0.1-0.6 micro-Sv $h^{-1}$ mainly due to $^{134}Cs$ and $^{137}Cs$ falling on the ground soil. This level is about double or up to ten times higher than the genuine natural level around the area. International Commission on Radiological Protection (ICRP) recommends how to face the existing exposure situation; that is the prolonged exposure situation. Referring to ICRP's reports and/or related international/domestic documents, we have been discussing how to manage this situation and acting to gain safety and relief of public, who have a possibility to be exposed to prolonged lower-dose radiation. Here, we introduce our several experiences on risk management, especially focusing on risk communication, radiation education to public, and stakeholder involvements into decision making in local governments on radiation protection, relating to the accident.

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Investigation of the suitability of new developed epoxy based-phantom for child's tissue equivalency in paediatric radiology

  • Yucel, Haluk;Safi, Aziz
    • Nuclear Engineering and Technology
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    • 제53권12호
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    • pp.4158-4165
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    • 2021
  • In this study, tissue equivalency (TE) of a newly developed epoxy-based phantom to 3-5 years child's tissue was investigated in paediatric energy range. Epoxy-based TE-phantoms were produced at different glandular/adipose (G/A) ratios of 17/83%, 31/69%, 36/64% and 10/90%. A procedure was developed in which specific amounts of boron, calcium, magnesium, sulphur compounds are mixed with epoxy resin, together with other minor substitutes. In paediatric energy range of 40-60 kVp half-value layer (HVL) values were measured and then Hounsfield Units (HU) were determined from Computed Tomography(CT) scans taken in the X-ray energy range of 80-120kVp. It is found that radiation absorption properties of these phantoms in terms of the measured HVL values related to linear attenuation coefficients (µ) are very well mimicking a 3 years child's soft tissue in case a ratio of 10/90%G/A. Additionally, the HU values of phantoms were determined from the CT scans. The HU = 47.8 ± 4.8 value was found for the epoxy-based phantom produced at a ratio of 10/90%G/A. The obtained HVL and HU values also support the suitability of the new epoxy based-phantom produced at a ratio of 10/90%G/A for a satisfactory mimicking a 3 years child's soft tissue by 5%. Thus they can have a potential use to perform the quality controls of medical X-ray systems and dose optimization studies.

Kinetic Models for the Quality Factors of Banana by Different Dehydration Methods (바나나의 건조방법(乾燥方法)에 따른 품질변화(品質變化) 인자(因子)에 대한 반응속도(反應速度) 모델링)

  • Kim, Su Yeon;Choi, Yong Hee
    • Current Research on Agriculture and Life Sciences
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    • 제7권
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    • pp.175-184
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    • 1989
  • Kinetics of ascorbic acid and browning that may use on the optimization of food dehydration were evaluated. Banana was chosen for this as the representative test material. We have described the destruction of ascorbic acid and browning as first and zero order reactions. The temperature dependence between two reactions were conducted with Arrhenius equation. Finally we have operated SPSS computer programs reapeatedly that we found very dose value of the parameter between result of ascorbic acid and browning. The attained Kinetic models were well prepared for the value of result experiments and the models may use on optimization for dehydration progress. Destruction rate of ascorbic acid and browning rate were low at initiation of progress, increased to show maximum at the low moisture on mid-progress and then decreased gradually. Freeze drying showed the most constant quality of product in this case.

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The Optimization of NDT Method for Real Time X-ray Imaging (X선 실시간 영상장치를 이용한 비파괴시험 조건 최적화 연구)

  • Na, Sung-Youb;Choi, Yong-Kyu
    • Journal of the Korean Society for Nondestructive Testing
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    • 제16권1호
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    • pp.19-28
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    • 1996
  • This study has investigated the optimization of NDT method and the minimum detectable defect size for complex structures such as the solid propellant rocket motor using real time X-ray imaging system. Test specimens were made of steel plates with various defect size, and installed with proper thickness for which solid propellant, rubber, and case converted to the steel equivalent thickness according to the radiographic equivalent theory. As the results, this examination obtained optimum magnification and X-ray energy, dose rate according to steel equivalent thickness, also, obtained the relationship between minimum detectable defect size and the ratio(defect depot/object thickness). Thus, this simulated test is the preliminary procedure before performing NDT for real objects, and is possibly applied for NDT of other complex structures.

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Mutual Authentication and Route Optimization between MN and CN using AAA in Mobile IPv6 (Mobile IPv6에서 AAA를 이용한 MN과 CN간의 상호 인증 및 경로 최적화)

  • 김미영;문영성
    • Journal of KIISE:Information Networking
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    • 제31권5호
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    • pp.429-437
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    • 2004
  • The mobileip working group is equipped with the RR(Return Routabilit) taking the simple procedures and small amount of cryptographic operations by considering the processing capability of the mobile node however it dose not provide security features enough. To replace with enhanced methods, mobileip WG is making an effort to find the approved solutions include CGA(Craptographically Generated Address), IPsec(Internet Protocol Security) as well as the existing infrastructure such as AAA(Authentication, Authorization and Account) and PKI(Public Key Infrastructure). In this paper, we propose the authentication and route optimization based on AAA suitable for the requested security service for its successful story in wireless network such as 802.11 and 3GPP(3rd Generation Partnership Project) as well as wired one. We analyze the effectiveness of our scheme according to the traffic and mobility properties. The result shows the cost reduction up to 20 percent comparing with RR.