• Title/Summary/Keyword: Dose mapping

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Dose-response relationship for annoyance caused by combined noise sources in urban spaces (외부 공간에서 복합소음에 대한 불쾌감 연구)

  • Lee, Pyoung-Jik;You, Jin;Jeong, Choong-Il;Yeon, Jun-Oh;Jeon, Jin-Yong
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2008.04a
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    • pp.264-267
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    • 2008
  • Relationship between exposure to combined noise sources and community annoyance have been investigated. Social surveys were conducted in urban spaces near the construction site with road traffics. The question relating to noise annoyance was answered on an 11-point numerical scale and 5-point verbal scale according to ISO 15666. The questionnaire also contained demographic factors, interference with daily activities, health-related symptoms, and noise sensitivity. Noise levels were measured in terms of A-weighted equivalent level ($L_{Aeq}$), and noise mapping technique was applied to predict the noise levels of urban spaces. Synthesis curves for the relationship between noise levels and percentage highly annoyed for combined noise sources were derived, and compared to the curves from a single noise source.

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The Seasonal Variation of Free Chlorine Residuals by Water Supply Distance in Daegu (대구 지역의 계절 변화에 따른 급수관내 잔류염소 농도 거동)

  • Lee, Tae-Gwan
    • Journal of Korean Society of Water and Wastewater
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    • v.19 no.3
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    • pp.363-369
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    • 2005
  • This paper presents the integrated technique of water quality analysis and Geographic Information System(GIS) for assessing the variation of free chlorine residuals by water temperature and supply distance in Sangri water supply system in Daegu. GIS was utilized for mapping projectmap, extraction of a pipeline route, and supply distance. Free chlorine residual is analyzed every month for appraising the seasonal variation. As a result, free chlorine residuals are affected both water temperature and water supply distance, and it becomes worse as water temperature and water supply distance is increased. To maintain 0.4mg/l of free chlorine residual, initial dose concentration should be over 1.85mg/l in summer.

From Radon and Thoron Measurements, Inhalation Dose Assessment to National Regulation and Radon Action Plan in Cameroon

  • Saidou;Shinji Tokonami;Masahiro Hosoda;Augustin Simo;Joseph Victor Hell;Olga German;Esmel Gislere Oscar Meless
    • Journal of Radiation Protection and Research
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    • v.47 no.4
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    • pp.237-245
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    • 2022
  • Background: The current study reports measurements of activity concentrations of radon (220Rn) and thoron (220Rn) in dwellings, followed by inhalation dose assessment of the public, and then by the development of regulation and the national radon action plan (NRAP) in Cameroon. Materials and Methods: Radon, thoron, and thoron progeny measurements were carried out from 2014 to 2017 using radon-thoron discriminative detectors (commercially RADUET) in 450 dwellings and thoron progeny monitors in 350 dwellings. From 2019 to 2020, radon track detectors (commercially RADTRAK) were deployed in 1,400 dwellings. It was found that activity concentrations of radon range in 1,850 houses from 10 to 2,620 Bq/㎥ with a geometric mean of 76 Bq/㎥. Results and Discussion: Activity concentrations of thoron range from 20 to 700 Bq/㎥ with a geometric mean of 107 Bq/㎥. Thoron equilibrium factor ranges from 0.01 to 0.6, with an arithmetic mean of 0.09 that is higher than the default value of 0.02 given by UNSCEAR. On average, 49%, 9%, and 2% of all surveyed houses have radon concentrations above 100, 200, and 300 Bq/㎥, respectively. The average contribution of thoron to the inhalation dose due to radon and thoron exposure is about 40%. Thus, thoron cannot be neglected in dose assessment to avoid biased results in radio-epidemiological studies. Only radon was considered in the drafted regulation and in the NRAP adopted in October 2020. Reference levels of 300 Bq/㎥ and 1,000 Bq/㎥ were recommended for dwellings and workplaces. Conclusion: Priority actions for the coming years include the following: radon risk mapping, promotion of a protection policy against radon in buildings, integration of the radon prevention and mitigation into the training of construction specialists, mitigation of dwellings and workplaces with high radon levels, increased public awareness of the health risks associated with radon, and development of programs on the scientific and technical aspects.

The Feasibility Study of MRI-based Radiotherapy Treatment Planning Using Look Up Table (Look Up Table을 이용한 자기공명영상 기반 방사선 치료계획의 타당성 분석 연구)

  • Kim, Shin-Wook;Shin, Hun-Joo;Lee, Young-Kyu;Seo, Jae-Hyuk;Lee, Gi-Woong;Park, Hyeong-Wook;Lee, Jae-Choon;Kim, Ae-Ran;Kim, Ji-Na;Kim, Myong-Ho;Kay, Chul-Seung;Jang, Hong-Seok;Kang, Young-Nam
    • Progress in Medical Physics
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    • v.24 no.4
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    • pp.237-242
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    • 2013
  • In the intracranial regions, an accurate delineation of the target volume has been difficult with only the CT data due to poor soft tissue contrast of CT images. Therefore, the magnetic resonance images (MRI) for the delineation of the target volumes were widely used. To calculate dose distributions with MRI-based RTP, the electron density (ED) mapping concept from the diagnostic CT images and the pseudo CT concept from the MRI were introduced. In this study, the look up table (LUT) from the fifteen patients' diagnostic brain MRI images was created to verify the feasibility of MRI-based RTP. The dose distributions from the MRI-based calculations were compared to the original CT-based calculation. One MRI set has ED information from LUT (lMRI). Another set was generated with voxel values assigned with a homogeneous density of water (wMRI). A simple plan with a single anterior 6MV one portal was applied to the CT, lMRI, and wMRI. Depending on the patient's target geometry for the 3D conformal plan, 6MV photon beams and from two to five gantry portals were used. The differences of the dose distribution and DVH between the lMRI based and CT-based plan were smaller than the wMRI-based plan. The dose difference of wMRI vs. lMRI was measured as 91 cGy vs. 57 cGy at maximum dose, 74 cGt vs. 42 cGy at mean dose, and 94 cGy vs. 53 at minimum dose. The differences of maximum dose, minimum dose, and mean dose of the wMRI-based plan were lower than the lMRI-based plan, because the air cavity was not calculated in the wMRI-based plan. These results prove the feasibility of the lMRI-based planning for brain tumor radiation therapy.

Proteomic Analysis and Protective Effects of Outer Membrane Proteins from Salmonella Gallinarum in Chickens (Salmonella Gallinarum 세포외막단백질의 프로테옴 분석 및 닭에서의 방어능 효과)

  • Sun, Jisun;Cho, Youngjae;Jang, Joo-Hyun;Kang, Zheng-Wu;Han, Jang-Hyuk;Hahn, Tae-Wook
    • Food Science of Animal Resources
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    • v.33 no.2
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    • pp.281-286
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    • 2013
  • Salmonella Gallinarum (SG) is known as an important pathogen that causes fowl typhoid in chickens. To investigate SG outer-membrane proteins (OMPs) as a vaccine candidate, we used proteomic mapping and database analysis techniques with extracted OMPs. Also, extracted OMPs were evaluated in several aspects to their safety, immune response in their host and protective effects. Our research has established a proteomic map and database of immunogenic SG-OMPs used as inactive vaccine against salmonellosis in chickens. A total of 22 spots were detected by 2-dimensional gel electrophoresis and immunogenic protein analysis. Eight spots were identified by Matrix-Assisted Laser Desorption/Ionization-Time of Flight-Mass spectrometry (MALDI-TOF-MS) and peptide mass fingerprinting (PMF) and categorized into four different types of proteins. Among these proteins, OmpA is considered to be an immunogenic protein and involved in the hosts' immune system. To estimate the minimum safety dose in chickens, 35 brown layers were immunized with various concentrations of OMPs, respectively. Consequently, all chickens immunized with more than a $50{\mu}g$ dose were protected against challenges. Moreover, intramuscular administration of OMPs to chickens was more effective compared to subcutaneous administration. These results suggest that the adjuvanted SG-OMP vaccine not only induces both the humoral and cellular immune response in the host but also highly protects the hosts' exposed to virulent SG with $50{\mu}g$ OMPs extracted by our method.

Image encryption using phase-based virtual image and interferometer

  • Seo, Dong-Hoan;Shin, Chang-Mok;Kim, Jong-Yun;Bae, Jang-Keun;Kim, Jeong-Woo;Kim, Soo-Joong
    • Proceedings of the IEEK Conference
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    • 2002.07a
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    • pp.631-634
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    • 2002
  • In this paper, we propose an improved optical security system using three phase-encoded images and the principle of interference. This optical system based on a Mach-Zehnder interferometer consists of one phase-encoded virtual image to be encrypted and two phase-encoded images, encrypting image and decrypting image, where every pixel in the three images has a phase value of '0' and '$\pi$'. The proposed encryption is performed by the multiplication of an encrypting image and a phase-encoded virtual image which dose not contain any information from the decrypted image. Therefore, even if the unauthorized users steal and analyze the encrypted image, they cannot reconstruct the required image. This virtual image protects the original image from counterfeiting and unauthorized access.. The decryption of the original image is simply performed by interfering between a reference wave and a direct pixel-to-pixel mapping image of the encrypted image with a decrypting image. Both computer simulations and optical experiments confirmed the effectiveness of the proposed optical technique for optical security applications.

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A New SLM Method using Dummy Sequence Insertion far the PAPR Reduction of the OFDM Communication System (OFDM통신 시스템의 PAPR저감을 위한 Dummy Sequence를 삽입하는 새로운 SLM 기법)

  • 이재은;허근재;김상우;유흥균
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.15 no.4
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    • pp.379-386
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    • 2004
  • OFDM(orthogonal frequency division multiplexing) communications system is very attractive for the high data rate transmissionin the frequency selective fading channel. Since OFDM has high PAPR(peak-to-average power ratio), OFDM signal may be distorted by the nonlinear HPA(high power amplifier). In this paper, we propose an improved dummy sequence scheme for reducing the PAPR in OFDM communication system. This method inserts each different dummy sequence at the predefined sub-carriers fur PAPR reduction. After IFFT, the OFDM data signal with the lowest PAPR is selected to transmit. The complementary sequence is used as dummy sequence. So, it can cut down the computation time and quantity because it dose not require the peak value optimization for finding the phase rotation factor and the transmission of the side information about the rotation factor unlike the PTS method.

Effect of GB 34-GB 39 Electro-acupuncture on Regional Cerebral Blood Flow in Stroke Patients and Normal Volunteers Evaluated by $^{99m}Tc-ECD$ SPECT (양릉천-현종 전침치료가 뇌경색환자 및 정상인의 뇌혈류에 미치는 영향 - SPECT와 SPM을 이용한 연구 -)

  • Han, Jin-An;Jeong, Dong-Won;Bae, Hyung-Sup;Park, Sung-Uk;Jung, Woo-Sang;Park, Jung-Mee;Ko, Chang-Nam;Cho, Ki-Ho;Kim, Young-Suk;Kim, Deok-Yoon;Moon, Sang-Kwan
    • The Journal of Korean Medicine
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    • v.27 no.3 s.67
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    • pp.187-200
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    • 2006
  • Objectives: Acupuncture has been applied in Asia for thousands of years, especially to rehabilitation after stroke. It has been reported that acupuncture increased cerebral blood supply and stimulated the functional activity of brain nerve cells shown by using brain imaging techniques. This study was to evaluate the effect of GB 34-GB 39 electro-acupuncture (EA) on regional cerebral blood flow (rCBF) in stroke patients and normal volunteers using single photon emission computed tomography (SPECT). Methods: The study procedure was divided into two parts: patients and volunteers studies. For the patients study, ten ischemic stroke patients (3 males, 7 females, mean age $68.5{\pm}8.9$ years old) were selected. Baseline brain SPECT was done with triple head gamma camera (MultiSPECT3, Siemens, USA) after intravenous administration of 1,110 MBq of $^{99m}Tc-ECD$. Fifteen-minute EA at GB 34 and GB 39 were applied on the affected limb. The same dose of $^{99m}Tc-ECD$ was injected during the EA, and the second set of SPECT images wasobtained. Using the computer software (ICON 7.1, Siemens, USA), 3 SPECT slices (upper, middle, lower) surrounding the brain lesion were selected and each slice was divided into 10-16 brain regions. Asymmetry indexes (AI) were analyzed in each brain region. We regarded over 10% changes of AI between before and after EA as significance. For the volunteers study, 10 healthy human volunteers (5 males, 5 females, mean age $28.1{\pm}6$ years old) were selected. In the resting state, $^{99m}Tc-ECD$ brain SPECT scans were performed. On the 7th day after the resting examination, 15 minute EA was applied at GB 34 and GB 39 on the right side of the subjects. Immediately after EA, the second SPECT images were obtained inthe same manner as the resting state. Significant increases and decreases of rCBF after EA were estimated by comparing their SPECT images with those of the resting state using paired t statistics at every voxel, which were analyzed by statistical parametric mapping with a threshold of p = 0.01, uncorrected (extent threshold: k=100 voxels). Results: In stroke patients, six of the eight (75%) had significantly increased perfusion in post-acupuncture scans compared to their baseline state. In normal volunteers, GB 34-GB GB EA increased rCBF in both hemispheres including right ventral posterior cingulate (Brodmann area (BA) 23), left superior temporal, anterior transverse temporal (BA 22, 41), left parastriate, peristriate (BA 18, 19), right occipitotemporal, angular (BA 37, 39), left rostral postcentral, caudal postcentral and preparietal (BA 2, 3, 5). However GB 34-GB 39 EA decreased rCBF in the right hemisphere including triangular and middle frontal lobes. Conclusions: The results demonstrated that OB 34-GB 39 EA increased cerebral perfusion in ischemic stroke patients and increased rCBF grossly in temporal lobes of normal volunteers. It is also suggested that there may be a correlation between the GB meridian and the territory of the middle cerebral artery.

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Coincidence Summing Corrections in HPGe Gamma Ray Spectrometry in Marinelli-beakers with Efficiency (효율을 적용한 마리넬리 비이커에서 HPGe 감마선 분광분석법의 동시합성보정)

  • Jang, Eun-Sung;Lee, Hyo-Yeong
    • Journal of the Korean Society of Radiology
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    • v.12 no.5
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    • pp.557-563
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    • 2018
  • Coincidence summing correction effects are known to be greater as the efficiency of the detector increases and as the distance between the source and the detector increases. A point source($^{60}Co$) was used to vary the distance in the direction of the detector's center axis and in the radial direction to obtain the P/T ratio for Coincidence summing correction calibration. In this study, values for coincidence summing corrected calibration of the values in the central and radial directions were applied to the mixed volume source(450 ml CRM source) to compare the overall peak efficiency change according to P/T with Geant4. In addition, the efficiency obtained from the mapping method is applied to the seaweed, a marine sample, and the compatibility of the P/T ratio with the detector and sample very dose together. The efficiency corrected to 1,836 keV was applied to the energy zone affected by the efficiency of 500 keV and the relative error of the measured and corrected values was well matcched by the 3.2 % peak efficiency correction. As with 450 mL CRM source, the larger the volume, the lower the P/T ratio was by ${\pm}5%$. This is due to the increased scattering of gamma-rays emitted as the source becomes farther away from the detector, and this change in P/T has been confirmed to affect the Coincidence summing corrected peak efficiency.

Effect of Acupuncture on Regional Cerebral Blood Flow at Acupoints GV 20, GV. 26, LI. 4, ST. 36, SP. 6 Evaluated by Tc-99m ECD Brain SPECT (Tc-99m ECD 뇌혈류 SPECT를 이용한 백회, 인중, 합곡, 족삼리, 삼음교에서 체침의 뇌혈류에 대한 효과)

  • Song, Ho-Chun;Bom, Hee-Seung;Kang, Hwa-Jeong;Ahn, Soo-Gi;Kim, Seong-Min;Jeong, Hwan-Jeong;Kim, Ji-Yeul
    • The Korean Journal of Nuclear Medicine
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    • v.34 no.6
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    • pp.456-464
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    • 2000
  • Purpose: To evaluate the effect of acupuncture on regional cerebral blood flow (rCBF) at acupoints suggested by oriental medicine to be related to the treatment of cerebrovascular diseases. Materials and Methods: Rest/acupuncture-stimulation Tc-99m ECD brain SPECT using a same-dose subtraction method was performed on 54 normal volunteers (34 males, 20 females, age range from 18 to 62 years) using six paradigms: acupuncture at acupoints GV. 20, GV. 26, LI. 4, ST. 36 and SP. 6. In the control study, needle location was chosen on a non-meridian focus 1 cm posterior to the right fibular head. All images were spatially normalized, and the differences between rest and acupuncture stimulation were statistically analyzed using SPM$^{(R)}$ for Windows$^{(R)}$. Results: Acupuncture applied at acupoint GV. 20 increased rCBF in both the anterior frontal lobes, the right frontotemporal lobes, and the left anterior temporal lobe and the left cerebellar hemisphere. Acupuncture at GV 26 increased rCBF in the left prefrontal cortex. Acupuncture at LI. 4 increased rCBF in the left prefrontal and both the inferior frontal lobes, and the left anterior temporal lobe and the left cerebellar hemisphere. Acupuncture at ST. 36 increased rCBF in the left anterior temporal lobe, the right inferior frontal lobes, and the left cerebellum. Acupuncture at SP. 6 increased rCBF in the left inferior frontal and anterior temporal lobes. In the control stimulation, no significant rCBF increase was observed. Conclusion: The results demonstrated a correlation between stimulation at each acupoint with increase in rCBF to the corresponding brain areas.

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