• 한국방사선학회논문지
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• 제12권4호
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• pp.541-547
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• 2018

흉부 디지털 단층합성(chest digital tomosynthesis, CDT) 검사 시 관전압 및 감도(sensitivity) 변화에 의한 선량감소 효과와 정량적 평가로 선량 최적화 조건을 평가하고자 한다. 관전압 125 kV, 135 kV 설정에 따른 sensitivity 200, 320, 400 변화하여 팬텀의 CDT 영상을 획득하였다. 감도와 관전압 변화 따른 선량과 면적선량(DAP)을 평가하였다. 화질평가는 최대신호 대 잡음비(PSNR), 대조도 대 잡음비(CNR), 신호 대 잡음비(SNR)를 image J를 이용하여 분석하였다. 선량은 14~23%, 면적선량은 13~26% 정도 sensitivity 200, 125 kV에 비해 측정치가 낮아졌고, sensitivity 가 높아짐에 따라 감소율 커짐을 알 수 있었다. PSNR은 27dB 이상으로 모두 의미 있는 수치였고, CNR, SNR은 sensitivity가 낮을수록 우수했으나, 항목마다 통계의 유의성은 달랐다. CNR과 SNR 모두 sensitivity 320, 135 kV가 sensitivity 200, 125 kV와 통계적으로 유의하지 않았다(p>0.05). CDT는 감도, 관전압과 디지털 촬영의 장비의 장점인 보정능력을 이용하여 더 작은 선량으로 화질을 유지 시킬 수 있다.

• Biomolecules & Therapeutics
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• 제9권4호
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• pp.277-281
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• 2001

Chromium is an essential nutrient and participates in glucose and lipid metabolism in human beings and animals. The present study was conducted to assess the effects of chromium picolinate (Cr-pic) on glucose tolerance and insulin sensitivity in type I and ll diabetic rats. The experimental groups were type I diabetic (streptozotocin-induced: 40 mg/kg, i.p.) and type II diabetic (Goto-Kakizaki rats) models. Each group was subdivided into control. low-dose and high-dose of Cr-pic treated groups. The Cr-pic was orally administered with Cr-pic (100 mg/kg for low dose group and 200 mg/kg for high dose group) for 4 weeks. And then we performed intraperitoneal glucose tolerance test (IPGTT) and insulin sensitivity test (ITT). The glucose tolerance test was carried out by inection of glucose (2 g/kg, i.p.). The peripheral insulin sensitivity test was con- ducted by injection of insulin (5 units/kg, s.c.) and glucose. We performed determining of blood glucose concentration at 0, 10, 30, 60, 90, and 120 min using automated glucose analyzer. The plasma insulin concentration was determined by rat insulin EIA kit. Administration of Cr-pic improved weight gain in all group s with higher significant in the low-dose group. There was no significance between the control and the Cr-pic treated groups in the area under the blood glucose curve and serum insulin concentration plots of IPGTT and peripheral ITT in type I diabetic rats. But Cr-pic treated groups showed significantly lower levels of the area under the blood glucose currie during IPGTT and ITT and the high-dose group showed less effects compared with the low-dose group in the type II diabetic rats. The plasma insulin concentration of both diabetic groups was not influenced by Cr-pic supplementation. We can conclude that chromium picolinate may improve the endogenous and exogenous insulin action and peripheral insulin sensitivity in type II diabetic rats.

• Nuclear Engineering and Technology
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• 제56권7호
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• pp.2790-2798
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• 2024

In this research, thermoluminescent pellets were prepared by adding Mg, Cu, Na and Si impurities to lithium fluoride (LiF) crystal powder via melting and quenching methods to study dosimetric characteristics. Here, its reproducibility, dose response, dosimeter sensitivity, thermal and optical fading were investigated and the obtained results were compared with the properties of LiF: Cu, Mg, P crystal nominated as GR-200.

• 한국의학물리학회지:의학물리
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• 제27권2호
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• pp.98-104
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• 2016

본 연구는 고선량으로 인한 광자극발광선량계의 방사선 민감도 변화에 관하여 분석하기 위하여 60-Co 감마선에서 상용화된 광자극발광선량계(Landauer, Inc., Glenwood, IL)를 이용하였다. 고선량으로 인한 방사선 민감도 변화를 분석하기 위하여 한번도 사용하지 않은 소자들을 이용하여 상대적 방사선 민감도 변화 경향을 확인하였으며, 7번째까지 3% 정도 증가하다가 그 이후 1 Gy의 조사 횟수에 따라 0.35%씩 감소하는 것을 확인하였다. 그리고 30회까지 조사하였을 때 7% 감소하였다. 고 선량을 받은 소자들의 경우, 15 Gy가 조사된 그룹은 한번도 사용하지 않은 소자들의 방사선 민감도에 비해 6% 감소하였으며, 30 Gy가 조사된 그룹은 12% 감소하였다. 감소되는 경향은 지수함수에 곡선 맞춤 하였다. 고선량을 받은 소자들을 다시 재 사용할 경우 측정에 대한 큰 불확도를 가지고 있으며, 이를 인지 하고 소자에 대한 조사 이력 관리를 하면서 사용해야 할 것이다.

• Nuclear Engineering and Technology
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• 제56권7호
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• pp.2781-2789
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• 2024

We developed lead gloves that minimize radiation dose to the operator's hands during interventional radiological procedures and that do not impede the operator's surgical capabilities. Existing lead gloves can protect the operator's hands by shielding radiation, but use of such gloves may impair preception sensitivity, resulting in a reduction in the operator's surgical ability. Accordingly, in this study, we developed modified lead gloves that can reduce radiation dose while maintaining operator sensitivity during procedures by modifying the operator's main surgical finger area in existing lead gloves. To evaluate the performance of developed modified lead gloves, radiation was applied in surgical conditions without gloves and with surgical gloves, lead gloves, and modified lead gloves. The radiation dose was evaluated for each condition. When the modified lead gloves were worn, the degree of shielding was similar to when conventional lead gloves were worn. Based on these results, if the operator wears modified lead gloves during interventional radiological procedures, they will protect the hands from radiation while maintaining physical sensitivity in the hands.

• 한국콘텐츠학회논문지
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• 제18권1호
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• pp.232-240
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• 2018

본 연구는 자동노출제어장치의 감도변화에 따른 흡수선량의 변화와 히스토그램을 이용하여 검출기 성능평가 방법을 제안하고자 하였다. 실험방법은 두개부, 복부, 골반부위 별로 검출기 감도 S200, S400, S800, S1000의 흡수선량을 측정하여 검출기의 정확성을 평가하였다. 또한 영상의 히스토그램 분석을 통하여 검출기의 감도별 동적범위를 평가하였다. 그 결과 부위 별 흡수선량은 감도가 S200에서 S1000으로 높게 설정될수록 흡수선량이 단계적으로 감소하였다. 감도 별 히스토그램을 분석한 결과 두개부는 감도가 높게 설정될수록 히스토그램의 양단의 정보량이 상실되는 결과를 보였다. 복부와 골반부는 감도가 높게 설정될수록 히스토그램의 첫부분의 정보량이 상실되는 언더플로우 현상을 보였다. 결론적으로 검출기가 감도의 변화는 정확하게 구현해 내었으나 검출기 성능저하로 인한 자동노출제어장치의 감도변화에 따른 영상의 동적범위는 제대로 구현해내지 못한다는 것을 알 수 있었고 검출기의 성능평가 시 흡수선량과 히스토그램을 통한 평가가 유용하다는 것을 알 수 있었다.

• 한국의학물리학회지:의학물리
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• 제32권4호
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• pp.179-184
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• 2021

This study aimed to determine the optimal thickness of the active layer and scan mode for a flexible radiochromic film (F-RCF) based on the active lithium salt of pentacosa-10,12-diynoic acid (LiPCDA). F-RCFs of 90, 120, 140, and 170-㎛ thickness were fabricated using LiPCDA. Several pieces of the F-RCFs were exposed to doses ranging from 0 to 3 Gy. Transmission and reflection modes were used to scan the irradiated F-RCFs. Their dose-response curves were obtained using a second-order polynomial equation. Their sensitivity was evaluated for both scanning modes, and the uniformity of the batch was also examined. For both the transmission and reflection modes, the sensitivity increased as the film thickness increased. For the reflection mode, the dose response increased dramatically under 1 Gy. The value of the net optical density varied rapidly as the thickness of the film increased. However, the dose-response curves showed a supralinear-curve relationship at doses greater than 2 Gy. The sensitivity of the reflection scan at doses greater than 2 Gy was higher than that of the reflection scan within 0-2 Gy. The sensitivity steadily decreased with increasing doses, and the sensitivity of the two modes was within 0.1 to 0.2 at 2 Gy and was saturated beyond that. For the transmission scan, the sensitivity was approximately 0.2 at 3 Gy. For the intra-batch test result, the maximum net optical density difference of the intra-batch was 5.5% at 2 Gy and 7.4% at 0.2 Gy in the transmission and reflection scans, respectively. In the low-dose range, film thickness of more than 120-㎛ was proper in the transmission mode. In contrast, the transmission mode showed a better result compared to the reflection mode. Therefore, the proper scan mode should be selected according to the dose range.

• 대한안전경영과학회지
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• 제17권4호
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• pp.199-206
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• 2015

The purpose of this study was to investigate radiation dose sensitivity due to displacement of human extremities in the water bolus box on radiation therapy. Water bolus box and human thigh with femur bone were constructed in computerized radiation therapy planning system to verify the absorbed dose. Two 6MV X-ray beams were irradiated bilaterally into water bolus box and then radiation dose were calculated each situation at displacement of middle axis of thigh from the center in water bolus box to right and left direction. Absorbed dose of thigh and femur bone increased by the distance of displacement. The maximum dose of thigh even increased 20% over than prescribed dose. This is in contrast to conventional concept of dose distribution in water bolus box. Based on this result, displacement of body site in the water bolus box have to be averted during radiation therapy.

• Nuclear Engineering and Technology
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• 제33권2호
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• pp.156-165
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• 2001

A radiological safety assessment was performed for a hypothetical near-surface radioactive waste repository as a simple screening calculation to identify important nuclides and to provide insights on the data needs for a successful demonstration of compliance. Individual effective doses were calculated for a conservative ground water pathway scenario considering well drilling near the site boundary. Sensitivity of resulting ingestion dose to input parameter values was also analyzed using Monte Carlo sampling. Considering peak dose rate and assessment time scale, C-14 and T-129 were identified as important nuclides and U-235 and U-238 as potentially important nuclides. For C-14, the dose was most sensitive to Darcy velocity in aquifer The distribution coefficient showed high degree of sensitivity for I-129 release.

• 한국의학물리학회지:의학물리
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• 제6권1호
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• pp.49-57
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• 1995

반도체검출기는 소형 및 방사선에 고감도특성을 갖고 있으나, 고에너지 광자선 및 전자선등의 조사에 의해 손상을 입어 감도저하를 초래하게 되며 계측시 선량재현성을 기대하기어려워진다. 실험대상은 P-형 실리콘 반도체검출기이며 선량율, 김출방향 및 온도 변화에 따른 선량특성이 조사되었고, 선량재현성을 높이기 위해 18 MeV 고에너지전자선으로 3KGy까지 전처리조사하고 광자선 및 전자선의 전처리조사선량에 대한 감도특성변화를 얻었다. 전처리조사가 작은 0.5KGy인 경우, 저선량율과 고선량율하의 단위선량당 감도는 약 35％의 차이를 보였으며 .3KGy인 경우 약 20％의 차이를 보여 전처리선량이 클 수록 감도차는 작아짐을 알수 있다. 실리콘 반도체검출기의 검출방향성은 임의의 조사각에서 최저치와 최대치의 선량차가 약 13％를 나타내었으며, 검출기의 온도의존성은 4도에서 35도까지 거의 선형성을 보였다.