• Title/Summary/Keyword: Dose Report

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CLARIFYING THE PARADIGM ON RADIATION EFFECTS & SAFETY MANAGEMENT: UNSCEAR REPORT ON ATTRIBUTION OF EFFECTS AND INFERENCE OF RISKS

  • Gonzalez, Abel J.
    • Nuclear Engineering and Technology
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    • v.46 no.4
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    • pp.467-474
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    • 2014
  • The aim of this paper is to describe a relatively recent international agreement on the widely debated concepts of: (i) attributing effects to low dose radiation exposure situations that have occurred in the past and, (ii) inferring radiation risk to situations that are planned to occur in the future. An important global consensus has been recently achieved on these fundamental issues at the level of the highest international intergovernmental body: the General Assembly of the United Nations. The General Assembly has welcomed with appreciation a scientific report on attributing health effects to radiation exposure and inferring risks that had been prepared the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) following a formal request by the General Assembly.

Effective Management of Gastroparesis with Erythromycin after Laparoscopic Nissen Fundoplication -A case report- (복강경 Nissen 위저추벽성형술 후 발생한 위배출지연에 대한 에리트로마이신의 유용한 효과 - 1예 보고-)

  • Jung, Eunyoung;Hwang, Jin-Bok;Choi, Soon-Ok;Park, Woo-Hyun
    • Advances in pediatric surgery
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    • v.18 no.1
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    • pp.30-34
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    • 2012
  • Delayed gastric emptying (DGE) commonly occurs after Nissen fundoplication in patients with gastroesophageal reflux disease. Since the understanding of its pathogenesis is insufficient, an effective method of management has not yet been suggested. The authors report a case of a 16-year-old girl with DGE after laparoscopic Nissen fundoplication and treated with intravenous injection of low dose erythromycin.

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Post-infectious basal ganglia encephalitis and axonal variant of Guillain-Barré syndrome after COVID-19 infection: an atypical case report

  • Yang, Jiwon;Shin, Dong-Jin;Park, Hyeon-Mi;Lee, Yeong-Bae;Sung, Young-Hee
    • Annals of Clinical Neurophysiology
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    • v.24 no.2
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    • pp.101-106
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    • 2022
  • Neurological complications attributed to coronavirus disease-19 (COVID-19) infection have been reported including acute disseminated encephalomyelitis, Guillain-Barré syndrome, and so on. Herein, we report a 49-year-old woman presented with acute encephalopathy and paraplegia simultaneously after COVID-19 infection. Brain magnetic resonance imaging (MRI) showed symmetric hyperintense basal ganglia lesions on T2-weighted imaging. Cerebrospinal fluid pleocytosis, motor axonal neuropathy and enhancement of conus medullaris nerve roots on spine MRI were observed. We treated her with high-dose corticosteroid and intravenous immunoglobulin.

A Case of Idiopathic Sequential Profound Bilateral Sudden Sensorineural Hearing Loss Occurring 37 Days After Unilateral Presentation

  • Woo, Joo Young;Ji, Chang Lok;Park, Geun Hyung;Yoon, Byungwoo
    • Korean Journal of Audiology
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    • v.25 no.4
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    • pp.235-240
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    • 2021
  • Sudden sensorineural hearing loss (SSNHL) is a common disorder; however, sequential, bilateral presentation of the disease is rarer than unilateral presentation. Clinical otologists usually focus on treating the side with impaired hearing when patients first present with unilateral SSNHL, and therefore, may not warn patients of the possibility of subsequent hearing impairment in the contralateral ear. Furthermore, it is professionally discouraging when a patient presents with profound, sequential SSNHL after initial treatment. This may adversely impact the doctor-patient relationship, even if the patient is offered the best possible care from their first visit. Herein, we report the case of a patient with profound, idiopathic, bilateral SSNHL with a time interval of 37 days between involvement of both ears. Even though high-dose steroids were administered intraorally and intratympanically, the patient's hearing was not restored, and the patient eventually required bilateral cochlear implant surgery. Our report demonstrates that sequential, profound, bilateral SSNHL may manifest without any specific signs.

A Case of Idiopathic Sequential Profound Bilateral Sudden Sensorineural Hearing Loss Occurring 37 Days After Unilateral Presentation

  • Woo, Joo Young;Ji, Chang Lok;Park, Geun Hyung;Yoon, Byungwoo
    • Journal of Audiology & Otology
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    • v.25 no.4
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    • pp.235-240
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    • 2021
  • Sudden sensorineural hearing loss (SSNHL) is a common disorder; however, sequential, bilateral presentation of the disease is rarer than unilateral presentation. Clinical otologists usually focus on treating the side with impaired hearing when patients first present with unilateral SSNHL, and therefore, may not warn patients of the possibility of subsequent hearing impairment in the contralateral ear. Furthermore, it is professionally discouraging when a patient presents with profound, sequential SSNHL after initial treatment. This may adversely impact the doctor-patient relationship, even if the patient is offered the best possible care from their first visit. Herein, we report the case of a patient with profound, idiopathic, bilateral SSNHL with a time interval of 37 days between involvement of both ears. Even though high-dose steroids were administered intraorally and intratympanically, the patient's hearing was not restored, and the patient eventually required bilateral cochlear implant surgery. Our report demonstrates that sequential, profound, bilateral SSNHL may manifest without any specific signs.

Invasive sphenoid sinus aspergillosis with normal findings on initial diagnostic tests that mimics Tolosa-Hunt syndrome-a diagnostic dilemma: a case report

  • Yu Hun Jeong;Jongsuk Choi;Byung-Jo Kim;Hung Youl Seok
    • Journal of Yeungnam Medical Science
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    • v.40 no.2
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    • pp.198-201
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    • 2023
  • Invasive sphenoid sinus aspergillosis can mimic Tolosa-Hunt syndrome (THS), leading to frequent misdiagnoses and potentially fatal consequences. We report a case of invasive sphenoid sinus aspergillosis initially misdiagnosed as THS. A 79-year-old man presented with right periorbital pain, ophthalmoplegia, and loss of vision. Initial evaluations including magnetic resonance imaging (MRI), were normal. He was first diagnosed with THS based on clinical features. The disease progressed despite high-dose intravenous steroid treatment, and an enhancing mass-like lesion was found in the right orbital apex, cavernous sinus, and sphenoid sinus on follow-up MRI. Aspergillosis was eventually confirmed by sphenoid sinus biopsy. The patient developed cerebral infarction and finally died despite being treated with amphotericin B. Given that invasive sphenoid sinus aspergillosis may initially resemble THS, high suspicion and rapid histological examination are important for diagnosis.

Dosimetric evaluation of Tomotherapy and four-box field conformal radiotherapy in locally advanced rectal cancer

  • Yu, Mina;Jang, Hong Seok;Jeon, Dong Min;Cheon, Geum Seong;Lee, Hyo Chun;Chung, Mi Joo;Kim, Sung Hwan;Lee, Jong Hoon
    • Radiation Oncology Journal
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    • v.31 no.4
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    • pp.252-259
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    • 2013
  • Purpose: To report the results of dosimetric comparison between intensity-modulated radiotherapy (IMRT) using Tomotherapy and four-box field conformal radiotherapy (CRT) for pelvic irradiation of locally advanced rectal cancer. Materials and Methods: Twelve patients with locally advanced rectal cancer who received a short course preoperative chemoradiotherapy (25 Gy in 5 fractions) on the pelvis using Tomotherapy, between July 2010 and December 2010, were selected. Using their simulation computed tomography scans, Tomotherapy and four-box field CRT plans with the same dose schedule were evaluated, and dosimetric parameters of the two plans were compared. For the comparison of target coverage, we analyzed the mean dose, $V_{nGy}$, $D_{min}$, $D_{max}$, radical dose homogeneity index (rDHI), and radiation conformity index (RCI). For the comparison of organs at risk (OAR), we analyzed the mean dose. Results: Tomotherapy showed a significantly higher mean target dose than four-box field CRT (p = 0.001). But, $V_{26.25Gy}$ and $V_{27.5Gy}$ were not significantly different between the two modalities. Tomotherapy showed higher $D_{max}$ and lower $D_{min}$. The Tomotherapy plan had a lower rDHI than four-box field CRT (p = 0.000). Tomotherapy showed better RCI than four-box field CRT (p = 0.007). For OAR, the mean irradiated dose was significantly lower in Tomotherapy than four-box field CRT. Conclusion: In locally advanced rectal cancer, Tomotherapy delivers a higher conformal radiation dose to the target and reduces the irradiated dose to OAR than four-box field CRT.

Electron Microscopic Studies on the Cellular Changes in the Liver of Ducklings Induced by Korean Aflatoxin B$_1$ (한국산 Aflatoxin이 오리새끼의 간장에서 유발시킨 병변에 관한 전자현미경적 연구)

  • Lee Kwang-Juing;Yoon Hwa-Juing;Lee In-ho
    • Journal of the korean veterinary medical association
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    • v.26 no.9
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    • pp.543-553
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    • 1990
  • This report describes the cellular changes induced in the livers of ducklings by a sin91e administration of aflatoxin B$_1$ produced by Korean Industrial Strain of the Aspergillus flavus, in order to examine the toxicity of the minimum dose of

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The Effect of Nimodipine on the Pharmacokinetics of Cyclosporine in Rabbits

  • Choi, Jun-Shik
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.419.1-419.1
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    • 2002
  • The purpose of this study was to report the pharmacokinetic changes of cyclosporine after oral administration of cyclosporine. 10 mg/kg. in rabbits coadministered or pretreated twice per day for 3 days with nimodipine. dose of 5 mg/kg, The area under the plasma concentration-time curve (AUC) of cyclosporine was significantly higher in rabbits pretreated with nimodipine than in control rabbits (p<0.01). showing about 149% increased relative bioavailability. (omitted)

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