• Title/Summary/Keyword: Dongjae

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New Method for Combining P-values in Meta-Analysis (메타분석에서 새로운 P-Value 결합 방법)

  • Seon, Jeongyeon;Kim, Dongjae
    • The Korean Journal of Applied Statistics
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    • v.26 no.5
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    • pp.797-806
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    • 2013
  • Meta-analysis is used in variety of areas to synthesize the results of previous studies. Among the methods for Meta-analysis, combining p-values is the simplest method; in addition Tippett (1931), Fisher (1932), Stuoffer at al. (1949), proposed various methods to combine p-values. We propose a new method to combine p-values based on exponential distribution. A Monte Carlo simulation study compares the power of the proposed methods with previous methods.

Maximum Tolerated Dose Estimation by Stopping Rule and SM3 Design in a Phase I Clinical Trial (제 1상 임상시험에서 멈춤 규칙과 SM3 디자인을 이용한 최대허용용량 추정법)

  • Kim, Byoungchan;Kim, Dongjae
    • The Korean Journal of Applied Statistics
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    • v.27 no.1
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    • pp.13-20
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    • 2014
  • Phase I Clinical Trials estimate a Maximum Tolerated Dose(MTD). In this paper, an MTD estimation method applied stopping rule is proposed for Phase I Clinical Trials. The suggested MTD estimation method is compared to the Continual Reassessment Method(CRM) method using a Monte Carlo simulation study.

Comparison of binary data imputation methods in clinical trials (임상시험에서 이분형 결측치 처리방법의 비교연구)

  • An, Koosung;Kim, Dongjae
    • The Korean Journal of Applied Statistics
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    • v.29 no.3
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    • pp.539-547
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    • 2016
  • We discussed how to handle missing binary data clinical trials. Patterns of occurring missing data are discussed and introduce missing binary data imputation methods that include the modified method. A simulation is performed by modifying actual data for each method. The condition of this simulation is controlled by a response rate and a missing value rate. We list the simulation results for each method and discussed them at the end of this paper.

Nonparmetric Method for Identifying Effective and Safe Doses using Placement (유효하고 안전한 용량 결정에 위치를 이용한 비모수적 방법)

  • Kim, Sunhye;Kim, Dongjae
    • The Korean Journal of Applied Statistics
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    • v.27 no.7
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    • pp.1197-1205
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    • 2014
  • Typical clinical dose development studies consist of the comparison of several doses of a drug with a placebo. The primary interest is to find therapeutic window that satisfying both efficacy and safety. In this paper, we propose nonparametric method for identifying effective and safe doses in linear placement using score function. The Monte Carlo simulation is adapted to estimate the power and the family-wise error rate(FWE) of proposed procedure are compared with previous methods.

A Study on the Architectural Characteristics and the Ritural Form of Kyodong-Hyangkyo (교동학교(喬棟鄕校)의 건축적 특성과 봉안형식에 관한 연구 - 초기형 향교의 특성규명을 위한 사례연구 -)

  • Kim, Eun-Joong
    • Journal of architectural history
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    • v.7 no.4 s.17
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    • pp.93-102
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    • 1998
  • There are several treatises about architectural characteristics of Hyangkyo. But those treatises usually treat with the types of site plans or structural characteristics without the historic background. So there needs the approaching methods with the historic background to study about the architecture of Hyangky. This study aims at the sample research about the architecture of Hyangkyo in beginnig period. Kyodong hyangkyo is the first building in hyangkyo. There are some architectural characteristics in this building comparing with the Hyangkyo in ripening period. Such characteristics apper in the site plan of educational spaces and in the floor plans of Myongryundang, Dongjae, Seojae. And there appear some characteristecs in ritual spaces such as the architectural structure of Daesungjun, and the position of stone establishment (Kwansedae, Saengdan) The ritual form of Kyodong hyangkyo has no special characteristics compering with the Hyangkyo in ripening period. These rictual form has kept the general rule of ritura form through the history.

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Nonparametric method using placement in a randomized complete block design (랜덤화 블록 계획법에서 위치를 이용한 비모수 검정법)

  • Sim, Sujin;Kim, Dongjae
    • Journal of the Korean Data and Information Science Society
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    • v.24 no.6
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    • pp.1401-1408
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    • 2013
  • Kim and Kim (1992) proposed typical nonparametric method for umbrella alternative in randomized block design with replications. In this paper, We consider a test procedure for umbrella alternatives in a randomized block design using extension of the two sample placement tests described in Orban and Wolfe (1982) and treatment tests described in Kim (1999). We perform a Monte Carlo study to compare the empirical powers of the test statistics for underlying distributions.

Nonparametric Tests for 2×2 Cross-Over Design

  • Gee, Kyuhoon;Kim, Dongjae
    • Communications for Statistical Applications and Methods
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    • v.19 no.6
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    • pp.781-791
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    • 2012
  • A $2{\times}2$ Cross-over design is widely used in clinical trials for comparison studies of two kinds of drugs or medical treatments. This design has many statistical methods such as Hills-Armitage's (1979) method or Koch's (1972) method. In this paper, we propose a nonparametric test for $2{\times}2$ Cross-over design based on a two-sample test suggested by Baumgartner et al. (1998). In addition, a Monte Carlo simulation study is adapted to compare the power of the proposed methods with those of previous methods.

Evaluation of Static/Dynamic Structural Strength for Automotive Round Recliner (자동차용 라운드 리클라이너 정적/동적 구조 강도 평가)

  • Lee Dongjae;Park Changsoo;Lee Kyoungteak;Kim Sangbum;Kim Heonyoung
    • Transactions of the Korean Society of Automotive Engineers
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    • v.13 no.1
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    • pp.140-146
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    • 2005
  • This study presents the development of a round recliner using the finite element method. That reduces the number of test repeating times and gives an information about stiffness. A simulation model of round recliner mounting seat module and tooth strength simulation are established using a PAM-CRASH and ABAQUS. With the optimization of gear profile, structural strength design of round recliner was achieved. The round recliner seat module simulation, structure strength simulation and a crash safety are requested by FMVSS test. Solution of round recliner optimum variable study and design problem are searched for round recliner stress, deformation and application. Also an examination of safety is made.

Development of magnetism in armchair graphene nanoribbons with edge functionalizations: A first-principles study

  • Shin, Dongjae;Kim, Yong-Hoon
    • Proceeding of EDISON Challenge
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    • 2017.03a
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    • pp.376-382
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    • 2017
  • Graphene nanoribbons with zigzag-shaped edge (zGNRs) are predicted to be magnetic insulator at the ground state, attracting significant interest in view of spintronic applications [1]. On the other hand, although they are energetically and thermodynamically more favored than zGNRs [2], graphene nanoribbons with armchair-shaped edge (aGNRs) have been less spotlighted than zGNRs due to the absence of magnetism. Herein, based on the combined density functional theory (DFT) and matrix Green's function (MGF) approach, we consider aGNRs functionalized with various molecular groups, and show that the spin polarizations develop for some of the considered aGNR edge functionalization cases. The origin of the induced magnetism will be discussed within the Lieb's theorem [3]. This work will provide a novel guidance for the development of graphene-based spintronic devices.

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Synchronous Bypass of Medium Voltage Motor Drive (고압인버터의 동기절체 기술)

  • Kim, Kyoungsue;Jeon, Jaehyun;Jang, Dongjae;Kim, Jeongbin
    • Proceedings of the KIPE Conference
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    • 2013.07a
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    • pp.40-42
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    • 2013
  • 고압인버터가 적용된 설비의 연속운전을 보장하기 위해 사용하는 절체 기능은 고압모터가 정지한 후 상용전원으로 모터를 기동하는 방법으로 기동 시 과전류와 고압모터 정지 시간 등이 문제점으로 나타난다. 이럴 경우, 고압인버터 출력전압을 상용전원과 동기화 한 뒤 절체하는 동기절체 기능을 사용하면 고압모터가 회전 중일 때에 절체할 수 있으므로, 절체 시 과전류를 줄일 수 있으며, 설비의 연속운전을 보장할 수 있다.

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