• Title/Summary/Keyword: Dominant index

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Single Nucleotide Polymorphisms in the Gc Gene for Vitamin D Binding Protein in Common Cancers in Thailand

  • Maneechay, Wanwisa;Boonpipattanapong, Teeranut;Kanngurn, Samornmas;Puttawibul, Puttisak;Geater, Sarayut Lucien;Sangkhathat, Surasak
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.8
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    • pp.3339-3344
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    • 2015
  • Background: This case-control study aimed to determine if there were any associations between the two single nucleotide polymorphisms (SNPs) in Gc, rs7041 (Asp416Glu) and rs4588 (Thr420Lys) and 3 common cancers (breast, lung and colorectal) in Thai patients. Materials and Methods: Two hundred and eighty two colorectal, 101 breast and 113 lung cancer patients were recruited from one institute during 2011-2013. The controls were age-matched volunteers who had a negative history of index cancers. In addition, vitamin D levels were compared among different genotypes in the 2 SNPs. Results: The minor allele frequencies of rs7041 (G) and rs4588 (A) were 0.32 and 0.24, respectively. Under the dominant model, the study found significant associations between minor-allele genotypes of the SNP rs7041 (TG/GG) and lung cancer (odds ratio [OR] 1.78, 95% CI 1.05-3.03). When subgroup analysis was performed according to sex and age at diagnosis, the study found that the minor-allele genotypes of rs7041 (TG/GG) were significantly associated with colorectal cancer in patients whose age at diagnosis was more than 60 years (OR 1.67, 95%CI 1.06-2.61) and the minor-allele genotypes of rs4588 (CA/AA) were significantly associated with colorectal cancer in males aged 60 years or less (OR 2.34, 95%CI 1.25-4.37). When SNP combinations (rs7041-rs4588) were examined, the TT-CA combination had a significant protective association with lung cancer (OR 0.44, 95% CI 0.22-0.85). On evaluation of serum 25(OH)D levels in 205 individuals without cancer (males 144, females 61), the proportion of subjects with low serum vitamin D (< 20 ng/ml) in those harboring CA or AA genotypes of rs4588 (41.7%) was significantly higher than the CC genotype (15.5%, p-value < 0.01). Conclusions: Genetic polymorphisms in Gc were associated with lung and colorectal cancers in Thai patients. Lower serum 25(OH)D in minor variants of rs4588 may explain this association.

Investigation of Lichen Species as a Biomonitor of Atmospheric Ozone in 'Backwoon' Mountain, Korea (백운산(白雲山) 서식(棲息) 지의류(地衣類)를 이용(利用)한 오존 민감성(敏感性) 지표종(地表種) 선발(選拔))

  • Hur, Jae-Seoun;Kim, Pan-Gi
    • Journal of Korean Society of Forest Science
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    • v.89 no.1
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    • pp.65-76
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    • 2000
  • Lichen flora of 'Backwoon' mountain, Korea, was investigated during the summer of 1998 and 1999 to screen out lichen species which can be used as a biomonitor for atmospheric ozone. The identified foliose or fructicose lichens in the area were classified into 9 families, 20 genera and 34 species. The dominant lichen species in the area were found to be Leptogium sp., Parmelia sp., Parmotrema sp., Phaeophyscia sp. and Cladonia sp. It was also found that lichen species showing a wide range of sensitiveness to air pollution were distributed in 'Backwoon' mountain. The Parmotrema austrosinense, P. tinctorum, Certrelia braunsiana and Ramalina yasudae collected in the area were exposed to ozone at the level of 200ppb, 8hr/day in controlled growth chamber for 2 weeks. Malondialdehyde(MDA), hydroperoxy conjugated dienes(HPCD), soluble protein content and OD435nm/OD415nm ratio for phaeophytinization of chlorophyll were measured and a pollution index(PI) was calculated for each lichen. Ozone exposure severely damaged to the lichens in the order of P. austrosinense>P. tinctorum>C. braunsiana>R. yasudae. P. austrosinens easily identified and widely distributed in Korea is likely to be a very useful biomonitor of air pollution, especially for ozone. These results indicate that Korean lichen species can be used as a biomonitor for air pollution to evaluate air quality contaminated with ozone.

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Indirect Evaluation of Aquatic Animal Diversity in Ilsan Lake through the Analysis of the Growing Condition and Stomach Contents of Largemouth Bass, Micropterus salmoides (큰입배스 Micropterus salmoides의 위 내용물 분석을 통한 일산호수 내 큰입배스의 생육상태 및 수생동물의 다양성 간접 평가)

  • Kim, I-Tae;Park, Jae-Rho;Kim, Weon-Jae
    • Journal of Korean Society of Environmental Engineers
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    • v.35 no.12
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    • pp.953-959
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    • 2013
  • In this study, through the analysis of the growth condition and prey of the largemouth bass, we tried to understand the characteristics of the aquatic animal community depending on the composition and shape of a artificial lake. The evaluation was conducted for Ilsan lake which is one of the largest urban artificial lakes in Korea. Weight gain rate of the Zone III (eco-zone) was more rapid based on the relationship of length and weight of largemouth bass. Total 16 and 9 species of fish were found in each Zone III and Zone I, II (artificial zones), which represented significantly higher diversity of fish species in Zone III than Zone I, II. Index of relative importance(IRI) was more diverse at Zone III and when considering the hunger rate the food stress was more serious at Zone I, II. the proportion of the population of fish, Zacco platypus revealed to be the dominant species, and Squalidus gracilis majimae and Rhinogobius brunneus inhabited only Zone III naturally rich. On account of low prey species diversity of Zone I, II, the Phylum Arthropoda like Heteroptera showed relatively higher prey ratio in stomach of largemouth bass than that of Zone III. It was possible to figure out aquatic animal community characteristics indirectly through analyzing the stomach contents of largemouth bass.

Study on the Ecological Restoration of Rock-exposed-cut-slope by Natural Topsoil Restoration Methods : In Case of Won-Ju Experiment (자연표토 복원공법에 의한 암절취비탈면의 생태적 복원에 관한 연구 : 원주사례지역을 중심으로)

  • Nam, Sang-Joon;Suk, Won-Jin;Kim, Nam-Choon
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.2 no.4
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    • pp.54-63
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    • 1999
  • This study was conducted to suggest the ecological restoration and environmentally friendly revegetation technology for the rock-exposed cut-slopes by the Natural Topsoil Restoration Methods (NTRM) with the following restoration objectives; (1) prevention or reduction of wind and water erosion, (2) provision of food and cover for variety of animal species, (3) improvement of the visual or aesthetic quality of the disturbed slopes. On Nov. in 1995, the 5cm thick layer of artificial soil and 2cm thick layer of straw-mulching was attached at rock-exposed cut-slopes by NTRM without using anchor wire and anchor pin. The main results during four years surveying on the ground-coverage effect, plant growth, species diversity and importance values were summarized as follows. 1. Artificial soil attached at rock exposed cut-slopes was not eroded until recovered by tree and herbaceous vegetation in spite of not using anchor wire and anchor pin. Also it shows low soil hardiness and has almost the same amount of bacteria and fungi with in surrounding natural topsoil. 2. In 'combination for the woody vegetation', Lespedeza cyrtobotrya, Albizzia julibrissin, Rhus chinensis, Indigofera pseudo-tinctoria occupied upper layer vegetation. Since three years after seeding, Indigofera pseudo-tinctoria had overwhelmed the other woody plants and cool season foreign grasses, Erigeron canadensis, Taraxacum mongolicum, Commelina communis, Arundinella hirta (Thunberg) and Oenothera erythrosepala grows at lower part of the vegetation, 3. The heights of the Rhus chinensis grows 1.8m, Indigofera pseudo-tinctoria 2.0m, so it seems that the objectives of woody vegetation with native plants could be accomplished. 4. After 4 years later after seeding in 'combination for the herbaceous vegetation', the most dominant plant was Indigofera pseudo-tinctoria, the next was in order of cool-season grasses, Taraxacum mongolicum, Erigeron canadensis, lxeris dentata (Thunberg), Oenothera erythrosepala, Arundinella hirta (Thunberg). The diversity index in 'combination for woody vegetation' was higher than that in 'combination for the herbaceous vegetation'. The tendency of the intrusion of secondary succession plants was more effective in 'combination for the herbaceous vegetation' than in 'combination for the woody vegetation'.

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Changes in Multi-channel Electrogastrography after Acupuncture Treatmet in Patients with Functional Dyspepsia (기능성 소화불량증 환자에서 침구 처치 후 다채널 위전도 소견의 변화)

  • Kim, Yoo-Seung;Ryu, Bong-Ha;Kim, Jin-Sung;Hong, In-A;Park, Young-Sun;Jung, Yong-Jae;Oh, Seung-Whan;Han, Ga-Jin
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.24 no.1
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    • pp.152-157
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    • 2010
  • The aim of this study was to investigate the effects of traditional Korean medical therapy in patients with functional dyspepsia evaluted using multi-channel electrogastrography. Before the treatment, the EGG of 14 outpatients (male 3, female 11) with functional dyspepsia were recorded and their dominant frequency(DF), percentage of gastric slow waves, percentage of Power ratio, and percentage of slow wave couplings were analysed. For 8 weeks, the patients received acupuncture treatment. After 8 weeks, EGG was rechecked and compared with the previous data. After treatment, normogastria was significantly increased in channel 1 and channel 3($53.70{\pm}18.94$% vs $72.64{\pm}15.49$% in channel 1, P<0.05; $79.74{\pm}18.09$ vs $90.86{\pm}8.86$ in channel 3, P<0.05). arrythmia was significantly decreased in channel 3($14.34{\pm}15.21$ vs $5.93{\pm}6.90$, P<0.05). The patients who had less severe decrease in EGG indexes showed improvement of those indexes through 8 weeks of outpatient care. EGG channel 3 was shown to be the most adequate standard of evaluation. But there was no significant improvement in slow wave coupling rate which is a new index of multichannel EGG.

Development of A Device Constantly Stimulating Tuning Fork and Variability of Its Vibration Perception Time (음차를 일정하게 자극하는 장치의 개발 및 이 장치로 측정한 진동 감지 시간의 변이)

  • Lee, Jong-Young;Hong, Dae-Yong;Yoon, Hyeong-Ryeol
    • Journal of Preventive Medicine and Public Health
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    • v.24 no.1 s.33
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    • pp.93-97
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    • 1991
  • The time honoured tuning fork at present widely available for examining vibration sensation is brought about the problem of great interobserver variation. To resolve t his problem, author developed a divice using electric magnet that stimulates constantly tuning fork. The perception time of vibration from tunung fork by this device was tested on the index finger of dominant hand of twenty eight subjects. It was 12.44 seconds on average and ranged from 9.47 to 17.25. Coefficient of variation of it was 16.89 percent. Correlation coefficient between test and retest after 30 minutes was 0.957(p<0.01). This device is portable. Test procedure in non-invasive, non-aversive and simple, can be performed within one minute, and does not require the skilled technician. It is felt that this device testing vibration perception time is suitable as screening tool for early detection of occupational peripheral neuropathy.

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Distribution of Weeds in Greenhouses of Gyeongnam Area (경남지역(慶南地域) 시설원예작물(施設園藝作物) 재배지(栽培地)에 발생(發生)하는 잡초(雜草)의 분포(分布))

  • Lee, J.J.
    • Korean Journal of Weed Science
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    • v.16 no.1
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    • pp.1-7
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    • 1996
  • In order to get basic information for establishing weed control methods in greenhouse, weed distribution was surveyed at 42 greenhouses in 10 cities and counties of Gyeongnam and Junnam area from September to December, 1995. Sixty nine weed species in 23 families which were composed of 28 annuals, 16 biennials and 25 perennials were identified. Broadleaf weed species was 50 species, followed by 8 species in grasses, and 11 species in sedges. Cruciferae was the most widely occurring family belong to 9 species, followed by 8 species in Compositae, Cyperaceae and Gramineae, respectively, 6 species in Polygonaceae, and the other 17 families have 1~3 species. The dominant weed species occurred in greenhouses based on summed dominance ratio of weeds were Cardamine flexuosa var. fallax, Digitaria sanguinalis, Eleusine indica, Stellaria aquatica, Centipeda minima, Mollugo pentaphylla, Portulaca oleracea, Rorippa islandica.

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Community Structure and Understory Vegetation Distribution Pattern of Fagus engleriana Stand in Is. Ulleung (울릉도 너도밤나무림의 군집구조와 하층식생의 분포특성)

  • Cheon, Kwang-Il;Jung, Sung-Cheol;Lee, Chang-Woo;Byeon, Jun-Gi;Joo, Sung-Hyun;You, Ju-Han;Lee, Seul-Gi;Choi, Cheol-Hyun;Park, In-Hwan
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.15 no.4
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    • pp.81-95
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    • 2012
  • This study was intended for Fagus engleriana stand in Is. Ulleung where the disturbance of vegetation has been caused by the exploitation and the increase of tourists. For the effective conservation and management on this issue, this study was conducted provide basic data. The sixteen study sites ($20{\times}20m$) were installed in the dominant Fagus engleriana stand and the base environment and vegetation were investigated. The Fagus engleriana stand was classified into two groups, The Fagus engleriana stand was classified into two groups, community A is Fagus engleriana-Sorbus amurensis and community B is Fagus engleriana-Acer pictum subsp. Mono by cluster analysis and community A were nothing signigicant by indicator species analysis. Community B were Eight species (Tsuga sieboldii, Camellia japonica, Dystaenia takesimana ect.) significant by indicator species analysis. The diameter class of 16cm to 25cm was 53.7% in population structure of Fagus engleriana, which was the highest and showed inverse J-distribution. Species diversity index (H') of investigated woody layer group ranged from 0.99 to 2.05 and that of under layer group ranged from 1.75~2.59. According to Non-metric Multidimensional Scaling (NMS) analysis, the woody layer was divided into community A developed in the region having relatively high sand content at high altitudes and community B formed at the place having relatively high clay content at low altitudes. Then this classification was significant through Multi-Response Permutation Procedures (MRPP) analysis. The distribution of understory vegetation through Detrended Correspondence Analysis (DCA) was induced by the silt content and cover degree of vegetation layer.

Seasonal Variation of Primary Productivity and Pigment of Phytoplankton Community Structure in the Seomjin Estuary (섬진강 하구역의 계절별 일차생산력 및 식물플랑크톤 색소 조성 변화)

  • Min, Jun-Oh;Ha, Sun-Yong;Chung, Mi-Hee;Choi, Bo-Hyung;Lee, Yeon-Jung;Youn, Seok-Hyun;Yoon, Won-Duk;Lee, Jae-Seong;Shin, Kyung-Hoon
    • Korean Journal of Ecology and Environment
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    • v.45 no.2
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    • pp.139-149
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    • 2012
  • Four in situ incubation experiments were conducted in May, August and November 2009, as well as February 2010 to determine the seasonal primary productivity and the community structure of phytoplankton at the Seomjin estuary. The primary production of phytoplankton ranged from 9 to 3560 mgC $m^{-2}\;d^{-1}$. Primary productivity was the highest in the summer season (August), which was influenced by improved optical and temperature conditions of the water, as well as the supply of nutrients derived from its surrounding watershed. Particularly, the upper station (SJ-1, SJ-2) of Seom-jin estuary showed a higher productivity, as a result of inflow of input nutrients originated from the terrestrial source. The fucoxanthin, as an index pigment of diatoms showed the highest concentration (0.74~9.51 ${\mu}g\;L^{-1}$) at all stations, occupying 30~80% to total Chl a concentrations. The phytoplankton species composition determination, using a microscope showed similar results to the pigment analysis, which indicated diatom Skeletonema costatum, as the dominant species. The primary productivity in Seom-jin estuary indicates temporally and spatially large variation, according to different environmental conditions. Also, Skeletonema costatum has euryhaline features with relatively higher contribution.

Phytoplankton Flora and Community Structure in the Lower Nakdong River (낙동강하류의 식물플랑크톤상과 군집구조)

  • Choi, Chul-Mann;Kim, Won-Il;Lee, Jong-Sik;Jung, Goo-Bok;Lee, Jeong-Taek;Moon, Sung-Gi;Kim, Jin-Ho
    • Korean Journal of Environmental Agriculture
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    • v.26 no.2
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    • pp.159-170
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    • 2007
  • This study was focused on the investigation of the phytoplankton flora and community structure for changing of water environment at the rivers in the lower part of Nakdong river, The samples for this study were collected every month from Jan. 2004 To Dec. 2004. the 196 species belonged to 94 genera were identified during this study periods. The number of species was recorded the maximum 124 taxa in summer and the minimum 69 taxa in winter, We observed the maximum taxa (92 taxa) at the site No. 20 and the minimum taxa (55 taxa) at the site No. 8, respectively. Among the phytoplankton communities, diatoms were dominated over 40% of total phytoplankton groups. Subdominant groups were green algae (over 20% of total phytplankton groups). During this study periods, the 60 species were investigated ecologically significant species (46 cosmopolitic species, 25 pollution indicator, 21 redtide causative species, 8 dominant species, and 7 frequently occurred species). According to the cluster analysis by similarity index, the study sites could be divided into 4 groups.