• Journal of the Korean Society for information Management
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• v.24 no.3
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• pp.363-383
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• 2007

Global map of science, which is visualizing large scientific domains, can be used to visually analyze the structural relationships between major areas of science. This paper reviewed previous efforts on global science map, and then tried to making a science map of Korea with some new methods. There are several research groups on making global map of science including Dr. Small and Dr. Garfield of ISI (now Thompson Scientific), SCImago research group at the University of Granada, and Dr. Borner's InfoVis Lab at the Indiana University. They called their maps as science map or scientogram and called the activity of mapping science as scientography. Most of the previous works are based on citations between scientific articles. However citation database for Korean journal articles is still under construction. This research tried to make a Korean science map with the text in the proposals suggested for funding from Korean Research Foundation. Two kinds of method for generating networks of scientific fields are used. One is Pathfinder network (PFNet) alogorithm which has been used in several published bibliometric studies. The other is clustering-based network (CBnet) algorithm which was proposed recently as an alternative to PFNet. In order to take into account both views of the two algorithms, the resulting maps are combined to a final science map of Korea.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2018.10a
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• pp.73-73
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• 2018

Bacterial leaf blight(BLB), caused by X. oryzae pv. oryzae(Xoo), is one of the most destructive diseases of rice due to its high epidemic potential. Understanding BLB resistance at a genetic level is important to further improve the rice breeding that provides one of the best approaches to control BLB disease. In the present investigation, a collection of 192 accessions was used in the genome-wide association study (GWAS) for BLB resistance loci against four Korean races of Xoo that were represented by the prevailing BLB isolates under Xoo differential system. A total of 192 accessions of rice germplasm were selected on the basis of the bioassay using four isolated races of Xoo such as K1, K2, K3 and K3a. The selected accessions was used to prepare 384-plex genotyping by sequencing (GBS) libraries and Illumina HiSeq 2000 paired- end read was used for GBS sequencing. GWAS was conducted using T ASSEL 5.0. The T ASSEL program uses a mixed linear model (MLM). T he results of the bioassay using a selected set of 192 accessions showed that a large number of accessions (93.75%) were resistant to K1 race, while the least number of accessions (34.37%) resisted K3a race. For races K2 and K3, the resistant germplasm proportion remained between 66.67 to 70.83%. T he genotypic data produced SNP matrix for a total of 293,379 SNPs. After imputation the missing data was removed, which exhibited 34,724 SNPs for association analysis. GWAS results showed strong signals of association at a threshold of [-log10(P-value)] more than5 (K1 and K2) and more than4 (K3 and K3a) for nine of the 39 SNPs, which are plausible candidate loci of resistance genes. T hese SNP loci were positioned on rice chromosome 2, 9, and 11 for K1 and K2 races, whereas on chromosome 4, 6, 11, and 12 for K3 and K3a races. The significant loci detected have also been illustrated, NBS-LRR type disease resistance protein, SNARE domain containing protein, Histone deacetylase 19, NADP-dependent oxidoreductase, and other expressed and unknown proteins. Our results provide a better understanding of the distribution of genetic variation of BLB resistance to Korean pathogen races and breeding of resistant rice.

• Journal of Digital Convergence
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• v.12 no.7
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• pp.133-145
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• 2014

Recently, Hospital information systems have the large databases by wide range offices for hospital management, health care to improve the quality of care. However, hospital information systems for information security measures are insufficient. Therefore, when we construct the hospital information system, we have to audit the information security measures for them, and we have to manage the ISMS(Information Security Management System) to maintain the information protection level through the risk managements. In this paper, we suggested the hospital information security audit model for the protection of health information privacy by the current hospital information systems, information security management system(ISMS), and hospital information security requirements and threats. We derived the check items compared with ISO27799 reflected the characteristics of the hospital. We classified the security domains as the physical, technical, administrative domain, and derived the check items for information security. We also designed the check lists by mapping the ISO27799 risk management process to improve the security and efficiency simultaneously. Our model by the five-point scale survey of IT experts was verified the suitability with the average of 4.91 points.

• Geophysics and Geophysical Exploration
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• v.10 no.1
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• pp.77-88
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• 2007

Following a successful bathymetric mapping demonstration in a previous study, the potential of airborne EM for seafloor characterisation has been investigated. The sediment thickness inferred from 1D inversion of helicopter-borne time-domain electromagnetic (TEM) data has been compared with estimates based on marine seismic studies. Generally, the two estimates of sediment thickness, and hence depth to resistive bedrock, were in reasonable agreement when the seawater was ${\sim}20\;m$ deep and the sediment was less than ${\sim}40\;m$ thick. Inversion of noisy synthetic data showed that recovered models closely resemble the true models, even when the starting model is dissimilar to the true model, in keeping with the uniqueness theorem for EM soundings. The standard deviations associated with shallow seawater depths inferred from noisy synthetic data are about ${\pm}5\;%$ of depth, comparable with the errors of approximately ${\pm}1\;m$ arising during inversion of real data. The corresponding uncertainty in depth-to-bedrock estimates, based on synthetic data inversion, is of order of ${\pm}10\;%$. The mean inverted depths of both seawater and sediment inferred from noisy synthetic data are accurate to ${\sim}1\;m$, illustrating the improvement in accuracy resulting from stacking. It is concluded that a carefully calibrated airborne TEM system has potential for surveying sediment thickness and bedrock topography, and for characterising seafloor resistivity in shallow coastal waters.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.141-141
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• 2017

The ubiquitin-proteasome pathway is the major regulatory mechanism in a number of cellular processes for selective degradation of proteins and involves three steps: (1) ATP dependent activation of ubiquitin by E1 enzyme, (2) transfer of activated ubiquitin to E2 and (3) transfer of ubiquitin to the protein to be degraded by E3 complex. F-box proteins are subunit of SCF complex and involved in specificity for a target substrate to be degraded. F-box proteins regulate many important biological processes such as embryogenesis, floral development, plant growth and development, biotic and abiotic stress, hormonal responses and senescence. However, little is known about the F-box genes in wheat. The draft genome sequence of wheat (IWGSC Reference Sequence v1.0 assembly) used to analysis a genome-wide survey of the F-box gene family in wheat. The Hidden Markov Model (HMM) profiles of F-box (PF00646), F-box-like (PF12937), F-box-like 2 (PF13013), FBA (PF04300), FBA_1 (PF07734), FBA_2 (PF07735), FBA_3 (PF08268) and FBD (PF08387) domains were downloaded from Pfam database were searched against IWGSC Reference Sequence v1.0 assembly. RNA-seq paired-end libraries from different stages of wheat, such as stages of seedling, tillering, booting, day after flowering (DAF) 1, DAF 10, DAF 20, and DAF 30 were conducted and sequenced by Illumina HiSeq2000 for expression analysis of F-box protein genes. Basic analysis including Hisat, HTseq, DEseq, gene ontology analysis and KEGG mapping were conducted for differentially expressed gene analysis and their annotation mappings of DEGs from various stages. About 950 F-box domain proteins identified by Pfam were mapped to wheat reference genome sequence by blastX (e-value < 0.05). Among them, more than 140 putative F-box protein genes were selected by fold changes cut-offs of > 2, significance p-value < 0.01, and FDR<0.01. Expression profiling of selected F-box protein genes were shown by heatmap analysis, and average linkage and squared Euclidean distance of putative 144 F-box protein genes by expression patterns were calculated for clustering analysis. This work may provide valuable and basic information for further investigation of protein degradation mechanism by ubiquitin proteasome system using F-box proteins during wheat development stages.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.6 no.4
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• pp.245-255
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• 2008

Korea Hydro and Nuclear Power Company(KHNP) conducted site investigations for a low and intermediate-level nuclear waste repository in the Gyeong Ju site. The site characterization work constitutes a description of the site, its regional setting and the current state of the geosphere and biosphere. The main objectives of hydogeological investigation aimed to understand the hydrogeological setting and conditions of the site, and to provide the input parameters for safety evaluation. The hydogeological characterization of the site was performed from the results of surface based investigations, i.e geological mapping and analysis, drilling works and hydraulic testing, and geophysical survey and interpretation. The hydro-structural model based on the hydrogeological characterization consists of one-Hydraulic Soil Domain, three-Hydraulic Rock Domains and five-Hydraulic Conductor Domains. The hydrogeological framework and the hydraulic values provided for each hydraulic unit over a relevant scale were used as the baseline for the conceptualization and interpretation of flow modeling. The current hydrogeological characteristics based on the surface based investigation include some uncertainties resulted from the basic assumption of investigation methods and field data. Therefore, the reassessment of hydrostructure model and hydraulic properties based on the field data obtained during the construction is necessitated for a final hydrogeological characterization.

• Korean Journal of Optics and Photonics
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• v.17 no.6
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• pp.507-513
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• 2006

In this paper, we propose an improved image encryption and fault-tolerance decryption method using phase wrapping and phase encoding in the frequency domain. To generate an encrypted image, an encrypting key which denotes the product of a phase-encoded virtual image, not an original image, and a random phase image is zero-padded and Fourier transformed and its real-valued data is phase-encoded. The decryption process is simply performed by performing the inverse Fourier transform for multiplication of the encrypted key with the decrypting key, made of the proposed phase wrapping method, in the output plane with a spatial filter. This process has the advantages of solving optical alignment and pixel-to-pixel mapping problems. The proposed method using the virtual image, which does not contain any information from the original image, prevents the possibility of counterfeiting from unauthorized people and also can be used as a current spatial light modulator technology by phase encoding of the real-valued data. Computer simulations show the validity of the encryption scheme and the robustness to noise of the encrypted key or the decryption key in the proposed technique.

• Journal of Microbiology
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• v.44 no.3
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• pp.301-310
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• 2006

Two pathways of ammonium assimilation and glutamate biosynthesis have been identified in microorganisms. One pathway involves the NADP-linked glutamate dehydrogenase, which catalyzes the amination of 2-oxoglutarate to form glutamate. An alternative pathway involves the combined activities of glutamine synthetase, which aminates glutamate to form glutamine, and glutamate synthase, which transfers the amide group of glutamine to 2-oxoglutarate to yield two molecules of glutamate. We have cloned the large subunit of the glutamate synthase (GOGAT) from Salmonella typhimurium by screening the expression of GOGAT and complementing the gene in E. coli GOGAT large subunit-deficient mutants. Three positive clones (named pUC19C12, pUC19C13 and pUC19C15) contained identical Sau3AI fragments, as determined by restriction mapping and Southern hybridization, and expressed GOGAT efficiently and constitutively using its own promoter in the heterologous host. The coding region expressed in Escherichia coli was about 170 kDa on SDS-PAGE. This gene spans 4,732 bases, contains an open reading frame of 4,458 nucleotides, and encodes a mature protein of 1,486 amino acid residues (Mr =166,208). The EMN-binding domain of GOGAT contains 12 glycine residues, and the 3Fe-4S cluster has 3 cysteine residues. The comparison of the translated amino acid sequence of the Salmonella GOGAT with sequences from other bacteria such as Escherichia coli, Salmonella enterica, Shigella flexneri, Yersinia pestis, Vibrio vulnificus and Pseudomonas aeruginosa shows sequence identity between 87 and 95%.

• The KIPS Transactions:PartD
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• v.17D no.1
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• pp.25-40
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• 2010

Service-Oriented Architecture (SOA) is a development paradigm for reusing services as an independent reuse unit. A service delivers a cohesive functionality through its external interface. Since services have unique characteristics which are not typically presented in conventional development approaches, there is a demand for effective approaches to developing services. Most of the current SOA methodologies presenta process where services are designed and developed from the requirements rather than reusing existing assets, which demands high cost and effort. Hence, a desirable approach is to be able to develop services by migrating from their existing legacy systems such as object-oriented system. A difficulty in this migration is that objects in object-oriented systems reveal characteristics which differ considerably from those of services. That is, objects are designed without considering commonalities among several consumers. In this paper, we first define mapping relationships between key artifacts in object-oriented system and those in SOA services. By these relationships and considering commonalities among several applications in a domain, we propose three systematic methods to migrate from object-oriented system to SOA services. Each method consists of a list of input and output artifacts and detailed guidelines which are performed in order. Through these methods, service developers can easily develop services with less effort.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.1
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• pp.210-217
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• 2013

The development of collaboration among information systems in accordance with changes in enterprises' business environment brings about the problems of duplication of the existing business services and increase in costs of maintenance. Accordingly, Web service has been suggested as the standard of distributed computing to prevent the duplication of services within the same business domain and to attain the services that are already being utilized. But since the data needed for Web services are not standardized, it is difficult for the users to find services that meet diverse business purposes. In this paper, we construct an ontology-based collaboration system for service interoperability. The ontology can support fusion service by finding services which are existed interdependently under the distributed environment for collaboration processing. The role of the collaborative system includes development, registration and call of services based on ontology. A local systems request collaboration support through the service profile. Collaborative system supports the development of service using the service profiles, represents the semantic association between real data through system ontology, and infers relationship between instances contained in the services. Based on this, we applied the travel booking services for collaboration system. As a result, service can be managed effectively preventing collision in collaborative system, and we verify that the mapping between system is reduced.