• International Journal of Computer Science & Network Security
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• v.22 no.7
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• pp.147-156
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• 2022

Ontologies are knowledge containers in which information about a specified domain can be shared and reused. An event happens within a specific time and place and in which some actors engage and show specific action features. The fact is that several ontology models are based on events called Event-Based Models, where the event is an individual entity or concept connected with other entities to describe the underlying ontology because the event can be composed of spatiotemporal extents. However, current event-based ontologies are inadequate to bridge the gap between spatiotemporal extents and participants to describe a specific domain event. This paper reviews, describes and compares the existing event-based ontologies. The paper compares various ways of representing the events and how they have been modelled, constructed, and integrated with the ontologies. The primary criterion for comparison is based on the events' ability to represent spatial and temporal extent and the participants in the event.

• Development and Reproduction
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• v.27 no.1
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• pp.39-46
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• 2023

Pumilio (Pum) is an RNA-binding protein and translational repressor important to diverse biological processes. In the Drosophila ovary, Pum is expressed in female germline stem cells (GSCs), wherein it acts as an intrinsic stem cell maintenance factor via repressing target mRNAs that are as yet mostly unknown. Pum recognizes the Pum binding sequence (PBS) in the mRNA 3'UTR through its C-terminus Puf domain. Translational repression is mediated through its N-terminal domain, but the molecular mechanism remains largely unknown. We previously showed that Bag-of-marbles, a critical differentiation-promoting factor of female GSCs, physically interacts with the N-terminus of Pum. We further showed that this interaction is critical to Bam inhibition of Pum repressive action in cultured cells, but the physiological relevance was not addressed. Here we design an in vivo GFP translational reporter bearing the PBS in its 3'UTR and show that GFP expression is reduced in cells wherein Pum is known to be active. Furthermore, we demonstrate in pum mutant ovary that this GFP repression requires Pum, and also that the sensor faithfully monitors Pum activity. Finally, we show that forced expression of Bam inhibits Pum-mediated repression, validating that Bam inhibits Pum activity in vivo.

• Proceedings of the KSME Conference
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• 2007.05b
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• pp.2947-2950
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• 2007

A 3D human ventricular model is proposed to simulate an integrative analysis of heart physiology and blood hemodynamics. This consists of the models of electrophysiology of human cells, electric wave propagation of tissue, heart solid mechanics, and 3D blood hemodynamics. The 3D geometry of human heart is discretized to a finite element mesh for the simulation of electric wave propagation and mechanics of heart. In cellular level, excitations by action potential are simulated using the existing human model. Then the contraction mechanics of a whole cell is incorporated to the excitation model. The excitation propagation to ventricular cells are transiently computed in the 3D cardiac tissue using a mono-domain method of electric wave propagation in cardiac tissue. Blood hemodynamics in heart is also considered and incorporated with muscle contraction. We use a PISO type finite element method to simulate the blood hemodynmaics in the human ventricular model.

• 제어로봇시스템학회:학술대회논문집
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• 1997.10a
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• pp.1800-1803
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• 1997

This paper presents new feedback actuators to achieve an accurate position control of a flexible gnatry robot arm. the translational motion in the plane is generated by two d.c.motors and controlled by emplying elecor-rheological(ER) clutch acutators. The generated motion can be continuously controlled by controlling the intensity of lectric field imposed to the ER fluid domain which tunes the transmitted torque of the ER clutch. n the other hand, during control action of the translational motion a flexible arm attached to the moving mass produces undesirable oscillatins due to its inherent flexibility. The oscillations are actively suppressed by applying feedback voltages to piezoceramic acutators bonded on the surface of the flexible arm. The control electric fields to be applied to the ER clutch and the control voltage for the piezoceramic actuator are determined via the loop shaping esign procedures(LSDP) in the H.inf. control technique. Comsequently, an accuate positiion control at the end-point of the flexible am is achieved during planar motion.

• Journal of the Korean Society for Nondestructive Testing
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• v.23 no.5
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• pp.497-519
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• 2003

Science and technology is an essential ingredient of the progress in modern society. Measurements enable action and actions enable results. Non-Destructive Evaluation (NDE) - the science and technology of measurements without affecting the Properties and performance of the test object is an interdisciplinary domain area of high significance far ensuring quality, productivity and safety thus enabling better qualify of lift to the inhabitants on this planet. The test object can be material, component, plant, earth, environment etc. Total qualify management, total productivity management, concurrent engineering and many other essential ingredients of success in plant engineering and manufacturing industry are dependent on NDE far success and good returns on investments.

• Journal of Mechanical Science and Technology
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• v.18 no.8
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• pp.1375-1387
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• 2004

A solution is given for the elastodynamic problem of a crack perpendicular to the graded interfacial zone in bonded materials under the action of anti plane shear impact. The interfacial zone is modeled as a nonhomogeneous interlayer with the power-law variations of its shear modulus and mass density between the two dissimilar, homogeneous half-planes. Laplace and Fourier integral transforms are employed to reduce the transient problem to the solution of a Cauchy-type singular integral equation in the Laplace transform domain. Via the numerical inversion of the Laplace transforms, the values of the dynamic stress intensity factors are obtained as a function of time. As a result, the influences of material and geometric parameters of the bonded media on the overshoot characteristics of the dynamic stress intensities are discussed. A comparison is also made with the corresponding elastostatic solutions, addressing the inertia effect on the dynamic load transfer to the crack tips for various combinations of the physical properties.

• Mycobiology
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• v.43 no.2
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• pp.150-156
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• 2015

2',4'-Dihydroxychalcone (2',4'-DHC) was identified from a heat shock protein 90 (Hsp90)-targeting library as a compound with Hsp90 inhibitory and antifungal effects. In the presence of 2',4'-DHC ($8{\mu}g/mL$), radial growth of Aspergillus fumigatus was inhibited 20% compared to the control, and green pigmentation was completely blocked. The expression of the conidiation-associated genes abaA, brlA, and wetA was significantly decreased (approximately 3- to 5-fold) by treatment with 2',4'-DHC. The expression of calcineurin signaling components, cnaA and crzA, was also significantly reduced. The inhibitory effects of 2',4'-DHC on metabolic activity and mycelial growth were significantly enhanced by combination treatment with itraconazole and caspofungin. Docking studies indicated that 2',4'-DHC bind to the ATPase domain of Hsp90. These results suggest that 2',4'-DHC act as an Hsp90-calcinurin pathway inhibitor.

• Journal of Institute of Control, Robotics and Systems
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• v.12 no.3
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• pp.277-283
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• 2006

A recently proposed method for stabilizing haptic interfaces and teleoperation systems was tested with a 'PHANToM' commercial haptic device. The 'Passivity Observer' (PO) and 'Passivity Control1er' (PC) stabilization method was applied to stabilize the system but also excited a high frequency mode in the device. To solve this problem, we propose a method to use a timevarying desired energy threshold instead of fixed zero energy threshold for the PO, and make the actual energy input follow the timevarying energy threshold. With the time-varying energy threshold, we make the PC control action smooth without sudden impulsive behavior by distributing the dissipation. The proposed new PO/PC approach is applied to PHANToM with high stiffness (K = 5000N/m), and stable and smooth contact is guaranteed. Resetting and active environment display problems also can be solved with the reference energy following idea.

• Proceedings of the KIEE Conference
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• 1992.07b
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• pp.1038-1040
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• 1992

Booster is used widely as one of the step-up DC/DC power converter in power conversion process for fuel cell power plant which have the electrical characteristic of the high current density and low cell voltage. In view of control system, booster can be unstable when it is operated in broad operation range because the transfer function of booster has zero in right half plane of s-domain. So for reliable operation, controller must make the system stable in whole working range. In this paper, the two control method such as digital PID control and fuzzy control is studied for booster output voltage regulation in fuel cell plant. The design procedure of PID control and fuzzy control is described. And the experiment of designed controller action is performed in various operation points for controller performance test.

• Industrial Engineering and Management Systems
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• v.6 no.1
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• pp.72-82
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• 2007

Business Rules are formal statements about the data and processes of an enterprise. They present projections of the organization's constraints and ways of working on their supporting information systems. Therefore, their collection, structuring and organization should be central activities within information systems. In an enterprise, business rules are used to represent certain aspects of a business domain (static rules) or business policy (dynamic rules). Hence, regarding problem domains in the organization, business rules are classified into two groups: static and dynamic business rules. The paper introduces a new concept of business rules, Extended Dynamic Business Rule (EDBR) which contains the results of the occurrence of business rule's action. The focus of this paper is in the organizing, defining and modeling of such business rules using Mineau's approach. Mineau's approach is an extension of Sowa's Conceptual Graph theory.