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Investigation of candidated genes for molecular characterization of DongGyeong dog populations (Gyeongju)

  • Park, Chang-Eun;Lee, Eun-Woo;Sung, Ki-Chang;Choi, Seog-Gyu
    • 한국동물위생학회지
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    • 제33권4호
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    • pp.361-366
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    • 2010
  • This study was carried out to investigate the characters of short-tailed dogs (DongGyeong dogs) with anatomical insights, molecular genetics in Gyeongju. The present study was conducted to further characterize of short-tailed dog population in Gyeongju. The short-tailed dog was analyzed in the distribution of 55 individual. The anatomical insights were by x-ray. For discovery of specific genes expressions were measured by Hot-start PCR analysis. Anatomy survey, the number of vertebral typical consists of more than 20. 88.9% of short-tailed dog populations consists of 3-8 vertebrates. The 54 individuals of the 47 observe the vestigial tailed of the sacrum. No detected sacrococcygeal vertebrae degradation individuals were malformation defects. The 3 genes were DEGs (differentially expressed genes) in Dong-Gyeong dogs. We succeeded in finding 3 novel DongGyeong dogs specific genes by using Hot-start PCR analysis, this study suggests that these novel genes may play role (s) in DongGyeong dogs.

노령견에서 발생한 거대 비장 혈종 증례 보고 (A Case of Massive Splenic Hematoma in a Geriatric Dog)

  • 정태호;최춘기;박철;최을수
    • 한국임상수의학회지
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    • 제33권4호
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    • pp.231-233
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    • 2016
  • A 10-year-old intact female, mixed breed dog presented with abdominal distention of 2 months duration and three days of decreased appetite. The patient was conscious and no other gross abnormalities were noted. A tentative diagnosis of idiopathic massive hematoma or hemangiosarcoma was made on evaluating all clinical findings. Splenectomy was performed for treatment of abdominal distention and histopathological investigation was initiated to confirm the diagnosis. The hematoma was extremely massive on gross morphology, with the size of $20.2{\times}12.4cm$ and the splenic mass was diagnosed as hematoma formation, with moderate to marked lymphoid hyperplasia and adjacent moderate extramedullary hematopoiesis, based on microscopic description of spleen histology. This is the first case report in veterinary literature of a dog with extremely rare splenomegaly, an unusually large hematoma, with no malignancy or remarkable clinical signs.

개 회장 평활근에 있어서 Histamine Receptor의 생리적 특성에 관한 연구 (Studies on the Physiological Properties of the Histamine Receptor of Ileal Smooth Muscle in Dog)

  • 김주헌;박영배;권종국
    • 대한수의학회지
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    • 제24권1호
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    • pp.17-23
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    • 1984
  • To validate the physiological properties of the histamine receptors of ileal smooth muscle in dog, the effects of adrenergic-, cholineric-, and H-receptor antagonists on the responses of ileal smooth muscle strips to histamine were investigated. The results were summarized as follows; 1. Histamine caused the contraction of ileal smooth muscle and the contractile responses were increased between the concentration of histamine $10^{-7}M$ and $10^{-5}M$ with dose-dependent manner in dog. 2. The shorter the treatment interval of histamine, the lower the contractile activity until the treatment interval extended to 40 minutes. 3. The contractile response induced by histamine was completely blocked by the pre treatment with a $H_1$-receptor blocker, chlorpheniramine and not by the pretreatment with a $H_2$-receptor blockers cimetidine. 4. The contractile response induced by histamine was not blocked by the pretreatment with a cholinergic receptor blocker, atropine. 5. The contractile response induced by histamine was not blocked by the pretreatment with an ${\alpha}$-adrenergic receptor blocker, phenoxybenzamine, or a ${\beta}$-adrenergic receptor blocker, propranolol. From these results, it was suggested that the contraction induced by histamine was elicited through $H_1$-receptor on the ileal smooth muscle in dog.

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진도견 정자형성계 세포들의 Lectin-binding patterns (Lectine-binding patterns of spermatogenic cells in the Jindo dog)

  • 박영석;이성호
    • 대한수의학회지
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    • 제36권3호
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    • pp.531-539
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    • 1996
  • The lectin-binding patterns in the testis of the sexually matured Jindo dog were investigated to study the distribution of glycoconjugates in the seminiferous tubule under light and transmission electron microscopy. Positive reactions to Wheat germ agglutinin(WGA) and Dolichos biflorus agglutinin (DBA) were observed in the Sertoli cell and in the residual body of spermatid with a stronger reaction in the Sertoli cell to the lectins than in the residual body. Strong reactions to Soybean agglutinin(SBA) and Peanut agglutinin(PNA) were observed in the acrosome vesicles of the Golgi- and cap-phase spermatid, while a moderate reaction was observed in the acrosome-phase, maturation-phase spermatid and the residual body. The acrosome area of the spermatid reacted intensively to Griffonia simplicifolia agglutinin( GS-I) when the cell was in the acrosome-phase and maturation-phase, and the same reaction to the GS-I was observed in the residual body. However, the seminiferous tubule did not react to Ulex europeus agglutinin I(UEA-I). The gold-labelling of the Sertoli cells with DBA resulted in positive reactions of the Sertoli cell column and processes when observed under the electron microscopy, while the Golgi-, cap- and acrosome-phase spermatids reacted positively to SBA in the peripheral low-dense area of the acrosome vesicle of spermatid. Based on these results, we concluded that differences in the lectin-binding pattern of the seminiferous tubules were recognized in the Jindo dog compared to other animals.

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개에서 발생한 나뭇잎에 의한 대장폐색의 대장 내시경적 진단 및 치료 (Colonoscopic Diagnosis and Treatment of Colonic Obstruction by the Leaves in a Dog)

  • 신범준;이재연;김수현;박지영;최호정;이영원;김명철;정성목
    • 한국임상수의학회지
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    • 제27권1호
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    • pp.113-116
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    • 2010
  • A 6-years-old 30 kg male Germen Shepherd dog was presented with the history of abdominal pain, intermittent vomiting and anorexia. Abdominal survey radiography and ultrasonography revealed marked colonic distention. Positive contrast radiography revealed a colonic obstruction between the transverse colon and descending colon. Foreign bodies were identfied during colonoscopy. The descending colon was inflated by the air of endocope then foreign bodies were moved to the descending colon. Foreign bodies were removed by the enema. The dog's clinical signs resolved following foreign body removal.

말티즈견에 발생한 기저세포종 (Basal cell tumor) 1례 (A Case of the Basal Cell Tumor Occurred in a Maltese Dog)

  • 김지용;박성준;이영원;정성목;조종기;김명철;신상태;손화영;김덕환;송근호
    • 한국임상수의학회지
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    • 제22권2호
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    • pp.166-169
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    • 2005
  • A 10 year-old castrated male Maltese dog with a mass on the right carpal joint was referred to the Chungnam National University Veterinary Medical Teaching Hospital. Mass size was 0.5 cm in width, 0.8 cm in length and 0.8 cm in height. Surface of the mass was hairless and ulcerated, and also the peripheral furs of mass were discolored by continuous licking. This case was diagnosed as basal cell tumor by fine needle aspiration and histopathologic examination. This dog didn't lick the carpal joint after surgery.

개에서 발생한 정상피종 진단 및 치료 1례 (A Case of the Seminoma Occurred in a Dog: Diagnosis and Treatment)

  • 서영민;송근호;박성준;정성목;최호정;이영원;윤기영;신상태;조성환;조종기
    • 한국임상수의학회지
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    • 제25권1호
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    • pp.44-47
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    • 2008
  • An unknown-aged intact male Yorkshire terrier dog with a mass on the right caudoabdominal region was referred to the Veterinary Medical Teaching Hospital at Chungnam National University. Mass size was 4.5 cm in width, 6 cm in length and 3.5 cm in height. This case was suspected to seminoma by physical examination, laboratory examination, radiography, ultrasonography, CT and fine needle aspiration. This dog followed by treatment with surgical excision. After surgery, this case was diagnosed as seminoma by histopathological examination.

개에서 발생한 결장직장 선암종 1례 (Colorectal Adenocarcinoma in a Dog)

  • 최호정;안지영;오이세;정성목;박성준;조성환;이영원
    • 한국임상수의학회지
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    • 제25권5호
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    • pp.429-433
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    • 2008
  • An 8-year-old, female Pointer dog was presented with weight loss, hematochezia, and dyschezia. For the diagnosis, physical examination, complete blood counts, serum chemistry, radiography, ultrasonography, computed tomography, colonoscopy, cytology and histopathological examination were performed. The complete blood counts and serum biochemistry results were within the reference range. Ultrasonographic findings were presented with the thickened wall of the colon and rectum. Colonoscopy revealed irregular and ulcerated mucosal surface, mass and luminal narrowing of colorectal lesions. There were thickened wall and contrast enhancement of the lesion in colorectal region on the computed tomography. The cytologic examination suggested the adenocarcinoma. Postmortem histopathologic examination revealed adenocarcinoma. Based on these findings, the dog was diagnosed with annular colorectal adenocarcinoma.

동경이의 체형 및 번식 능력에 대한 실태조사 (Investigation of trunk conformation and reproductive activity in Donggyeongi)

  • 최석규;성기창;이은우;박창은
    • 한국동물위생학회지
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    • 제35권3호
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    • pp.207-213
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    • 2012
  • The trunk conformations of the Gyeongju Donggyeongi (GD), Korean native dog was measured in the present study. Also, the information of reproductive activity was investigated in GD dogs. A total of 73 dogs were randomly selected out of 121 dogs in the Gyeongju County in July 2010, which were registered by inserting electronic chips in the withers. The hair colors of the GD were white, yellow, black and tiger brindle, the mean withers heights were $45.46{\pm}4.17cm$ and $49.28{\pm}3.56cm$ for female and male dogs, respectively The mean body length to withers height ratios were 117.63% and 116.4% for the female and male dogs. Concerning the reproductive capability of the GD, the mean litter number was $4.6{\pm}1.7$, the optimal mating time was $12.5{\pm}2.3$ days after the rutting season and the mean gestation period was $60.2{\pm}2.8$ days. The results of this study would be useful for compiling the official standard for the adult GD.

Malignant Metastatic Plasma Cell Tumor in a Dog

  • Park, Jae-Hoon;Kim, Jin-Hyun;Lee, Jung-Kenn;Youn, Hwa-Young;Yoon, Jung-Hee;Kim, Dae-Yong
    • 한국수의병리학회:학술대회논문집
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    • 한국수의병리학회 2001년도 추계학술대회 및 정기총회
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    • pp.28-28
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    • 2001
  • A primary metastatic malignant plasma cell tumor was diagnosed in a 7-year-old, female mixed breed dog. The dog was admitted to Veterinary Teaching Hospital at College of Veterinary Medicine, Seoul National University after suffering from depression, anorexia, and dyspnea. In radiographic examination, a large occupying mass was found at the right cranial thorax. Due to poor prognosis, the dog was euthanized. At surgery, numerous, firm, round, nodules, 1 to 2 cm in diameter were noted in the ribs. The nodules were often confluent and had cylindrical appearance. Osteolysis was associated with the nodules. A large amount of clear fluid was present in the thoracic cavity. The spleen and liver were markedly enlarged and congested. Histologically, the mass was diagnosed as plasma cell tumor which was believed to be originate from the rib. Evidence of metastasis was observed in the spleen, liver, and kidney.

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