• 사상체질의학회지
• /
• 제12권2호
• /
• pp.171-183
• /
• 2000

1. Back ground and purpose An experimental study has done to examine the effect of defense and cure gastric mucasal damage of Mokdan-pijihwang-tang. 2. Methods Mice had intragastric injected with MJ extract before indomethacin treatment which induces homorrhage infarct and erosion artificially. Degree of lipid peroxidation, general morphology, change of mucous cell, the distribution of PNA, ICAM and distribution of apoptotic cell were objected. (Abbreviation) MJ : Mokdanpijihwang-tang, PNA : Peanut Agglutinin, ICAM : Intercellular Adhesion Molecule 3 Results 1) The degree of lipid peroxidation in INDO-group had increased conspicuously than control group. But the degree of lipid peroxidation in MJ-group had decreased than INDO-group and these decline had probability. 2) After indomethacin treatment, hemorrhage infarct and erosion had increased in stomach body. But in MJ-group, the configuration is normal, except the group intragastric injected with MJ extract at hour 24 before indomethacin treatment. 3) Surface mucous cell and neck mucous had disappeared in INDO-group. But in MJ-group tormal distribution had shown like control group except the group intragastric injected with MJ extract at hour 24 before indomethacin treatment. 4) PNA positive reaction had not shown in INDO-group. But medium PNA positive reaction had shown In Mj-group. 5) ICAM positive reacted cell had shown in INDO-group. The decrease of ICAM positive cell were shown than INDO-group. 6) A number of apoptotic cell was distributed in hemorrhagic erosion. A few number of apoptotic cell was distributed in MJ-group except some surface mucous. 4. Conclusion These results suggest that MJ has an effect on cure of gastric mucosal damage.

• 사상체질의학회지
• /
• 제13권1호
• /
• pp.109-118
• /
• 2001

1. The purpose of this study This study was performed on the basis of clinical consideration about rhinitis patients who suffered from sneeze, rhinorrhea, rhinocleisis and etc. And we checked the clinical inclination of this disease and the characteristic treatments of Sasang Constitutional Medicine. 2. The method of this study For 17 months from October in 1999 to April in 2001 we selected outpatients who had consulted for rhinitis more than twice in the department of the Sasang Constitution of the Bundang Oriental medical hospital, Dongguk University, and 31 of those were confirmed of their course of treatment. From their medical records and history, we learned the general characterisics and patterns of rhinitis, and the qualities and effects of its various treatment. 3. The result of this study The result were as follows ; 1) The rate of patients who have had the symptoms over the two years was 74.2%. 2) In the distribution of chief symptoms, sneeze occupied 80.6% of all appealed symptoms, rhinocleisis 77.4%, rhinorrhea 71.0%, intranasal pruritus 54.8%, postnasal drip 16.1%, orderly. 3) The treatment period was about 30days. The method of treatment was the Herb-med Tx, acupuncture Tx and etc. The herb-med ingestion was about two times in that period. 4) On the effect of treatment, Sneeze and rhinocleisis were improved. 5) The symptoms of rhinitis was more depravated by fatigue and stressful condition than weather condition. This result shows that the improvement of general condition has an effect on the rhinitis treatment.

• 사상체질의학회지
• /
• 제17권3호
• /
• pp.12-21
• /
• 2005

1. Objectives Though the distributional rate of Sasangin was mentioned in ${\ulcorner}$Dongyi Suse Bowon${\lrcorner}$, there were few studies on the distributional rate of Sasangin in Korea. So, this study was conducted to estimate the distributional rate of Sasangin in Korea. 2. Methods The medical records of 1,423 subjects who have taken diagnosis of Sasang constitution from January 2003 to June 2003 at a health examination center of a hospital in Seoul were reviewed. Then distributional rate of Sasang constitution were analyzed and age sex-adjusted standardized distributional rate were estimated by direct standardization using a reference population of 2000 aged from 20 to 70 years. 3. Results and Conclusions (1) The total number of subjects were 1,423(Males : 704(49.5%) / Females : 719(50.5%)). And the mean age of the subjects was $46.3{\pm}11.4$ years(males : $45.4{\pm}11.3$ / females $47.1{\pm}11.4$). (2) Among the 1,423 subjects, distributional rate of Taeumin, Soyangin, and Soeumin were 46.9%, 29.1% and 24.0%(Male : Taeumin 48.2%, Soyangin 37.9%, Soeumin 13.9% / Female: Taeumin 45.6%, Soyangin 20.4%, Soeumin 33.9%). (3) Age sex-adjusted standardized distributional rate of Taeumin, Soyangin, and Soeumin were 45.4%, 28.2% and 26.4%(Male : Taeumin 50.8%, Soyangin 35.1%, Soeumin 14.1% / Female: Taeumin 39.5%, Soyangin 21.0%, Soeumin 39.4%) (4) The rate of Soeumins was higher than that mentioned in ${\ulcorner}$Dongyi Suse Bowon${\lrcorner}$,and the distributional rate of Sasangin according to sex was different. (5) So it was thought that the distributional rate of Sasangin in Korea was different from that mentioned in ${\ulcorner}$Dongyi Suse Bowon${\lrcorner}$.

• 동의생리병리학회지
• /
• 제19권5호
• /
• pp.1411-1418
• /
• 2005

Obesity is not classed in general psychiatry disease. But, psychoneurotic factor has been known to be a risk factor of obesity. In order to evaluate and understand the psychoneurotic state on obese patient, this study used Minnesota Multiphasic Personality Inventory(MMPI). Total patients were classified into 3 or 5 clusters. MMPI scores were compared according to education, BMI and Sasang Constitution. Multiple regression analysis were used for psychological factor on obese patients by age, height, weight, education, percent body fat, fat distribution, BMI. Based on this study, it was no significantly difference by education level, BMI, sasang(四象) constitution except L profile according to BMI. These result is different from our general recognition of the psychoneurotic state on obese patient. Therefore, the bigger sample study is needed.

• 대한한의학회지
• /
• 제24권3호
• /
• pp.118-129
• /
• 2003

Objective : To learn the distributional characteristics of Sasang constitutions, Methods : We statistically analyzed those 1338 patients who had been treated at Iksan Wonkwang Oriental Medicine during the period of three years from 2000 to 2002. The data were obtained through the electronic chart developed by Kim Jong- Yeol, and analyzed using the statistical Package SPSS. Results : The distributional ratio of Soeumin : Soyangin : Taeumin was 22.8 : 29.2 : 47.8. Thus the hypothesis : 'the distributional ratio of Soeumin : Soyangin : Taeumin is 2 : 3 : 5' was barely rejected by $x^2$ test for goodness-of-fit at the significance level of 5 %. When $x^2$ test for homogeneity was applied, the distributional characteristics between women and men were different and the distributional characteristics among several age groups were different under significance level of 5%. Conclusion : Though the hypothesis: 'the distributional ratio of Soeumin : Soyangin : Taeumin is 2 : 3 : 5' was rejected by $x^2$ test at the significance level of 5%, the observed distributional ratio was not so far away from the hypothesis.

• 사상체질의학회지
• /
• 제30권3호
• /
• pp.62-73
• /
• 2018

Objectives The aim of this study was to make an analysis of clinical characteristics and status of Sasang constitutional medicine of patients with Parkinson's Disease who visited a Korean medicine hospital. Methods We studied 129 patients with Parkinson's Disease who visited a Korean medicine hospital from September 1, 2012 to June 30, 2018. We retrospectively collected medical history and characteristics of subjects using data of EMR (electronic medical record). Results The proportion of female was higher than male. The average age was 60s. The patients visited a hospital more than one year after the occurrence of symptoms. And they were mostly under western medicine treatment. Among the 129 patients, 56 persons(43.4%) were Taeeumin, 45 persons(34.9%) Soyangin and 28 persons Soeumin(21.7%). In the distribution of prescription according Sasang Constitutional Medicine symptomatology, there was no significant difference in the proportion of exterior cold disease(48.9%) and interior heat disease(51.1%) in Soyangin. Meanwhile the proportion of heat disease's prescription was higher than cold disease in Taeeumin(73.2%) and Soeumin(84.1%). The majority of disease were Dry-febrile symptom(73.2%) of heat disease in Taeeumin, Yang depletion-syndrome(64.3%) of heat disease in Soeumin, and Gyolhyung-symptom(33.3%) of exterior cold disease and Wasting thirst-syndrome(22.2%) of interior heat disease in Soyangin, Conclusions By Developing of guideline for treatment of Parkinson's Disease through analyzing on clinical characteristics and distribution of Sasang Constitutional Medicine symptomatology could contribute to the improvement of the cure rate and accuracy of constitution pattern.

• 사상체질의학회지
• /
• 제26권3호
• /
• pp.304-317
• /
• 2014

Objectives The purpose of this study was to find out whether there were differences of urticaria's disease aspect between patients classified into Sasang Constitution Types(SCTs) and whether those differences could be associated with Ordinary symptoms. Methods Medical records and questionnaires about 117 patients who visited one Korean medicine hospital due to urticaria were collated and statistically analyzed. Results 1) Ages 20 to 30, women, Soeumin(SE) and patients in conditions of chronic urticaria over 6 weeks were the majority among 117 patients in this study. Food and stress were most chosen as the main cause of urticaria. 2) Soyangin(SY) showed more severe symptoms of urticaria than other SCTs. In particular, the severity of pruritus, distribution of lesions and vulnerability to stress was statistically significant compared to other SCTs(p<0.05). SE expressed urticaria's symptoms at the medium-level of SY's and Taeeumin(TE)'s. TE exhibited relatively weak symptoms but TE only had slightly higher number of patients with angioedema compared to other SCTs. Taeyangin(TY) was only one case so more researches are needed. 3) In dispositional symptoms, SY had low quality of sleep and defecation. SE could not digest oily food well, felt dizzy and cold well, and had cold hands and feet. TE could eat and sweat much and tended to snore well. Conclusions In this study, urticaria had common cause of both stress and food in all SCTs but onset and severity of symptoms were different between SCTs. It could interpreted that these differences between SCTs were associated with ordinary symptoms native to each SCT.

• 동의생리병리학회지
• /
• 제19권2호
• /
• pp.515-519
• /
• 2005

We hypothesized that the IL10 gene is important candidate in the development of Bell's palsy and specific genotypic and allelic variations should be associated with Bell's palsy in the Korean population. In this study, we assessed the SNP (single-nucleotide polymorphism) of IL10 in patients with Bell's palsy. 62 patients with Bell's palsy were selected from the subjects who visited for the Bell's palsy service of the department of acupuncture & moxibustion, college of Oriental Medicine, Daegu Haany University from May 2002 to May 2003. Pyrosequencing was performed for genetic analyses. There was no statistically significant genotypic distribution difference between control and Bell's palsy group And there was not statistically significant allelic frequency difference between control and Bell's palsy group. In this study the IL10 genotypemight not be the risk factor of Bell's palsy patients in Korean. studies will be necessary for the exact genetic markers. Establishment of more systemic approach and high quality of prospective cohorts will be necessary for the good prediction of genetic markers.

• 대한중풍순환신경학회지
• /
• 제8권1호
• /
• pp.22-27
• /
• 2007

Objectives : This study was aimed to assess the distribution of metabolic syndrome according to Sasang constitution(SC) in acute stroke patients. Methods : We assessed the type of SC of acute stroke patients in the oriental medical hospitals of 3 universities located in metropolitan region from October 2005 to June 2007 by Ouestionnaire for the Sasang Constitution Classification II(QSCC II). Then, we investigated the general characteristics, the prevalence of each factor of the metabolic syndrome and the prevalence of the metabolic syndrome according to SC. Results : 338 subjects were included into the final analysis. 1. This study showed that the proportion of So-yang was highest of all constitutions(45.9%). 2. The prevalence of high TG, low HDL-chol, high BP, high FBS of Tae-um were higher than those of the other constitutions, but the differencecs were not statistically significant. The prevalence of high WC of Tae-um was significantly higher than other constitutions(p<0.001). 3. The prevalence of metabolic syndrome of Tae-um was significantly higher than other constitutions (p=0.002). Conclusion : There were significant differences in the prevalence of metabolic syndrome according to SC in acute stroke patients. For the further research, it seems to be necessary to construct fundamental databases for stroke by increasing the number of patients and by diagnosing SC more delicately.

• Journal of Acupuncture Research
• /
• 제30권4호
• /
• pp.55-68
• /
• 2013

Objectives : The purpose of this study is to analyze the distribution, relationship, prognosis and improvement score of idiopathic facial palsy inpatients according to constitutional differentiation ; Sasang constition, Hyungsang classification, Sasang constition combined with Hyungsang classification. Methods : A study was done on 102 patients who were diagnosed and treated as idiopathic facial palsy from April 2012 to Nomember 2012 at the Department of Acupuncture and Moxibution Medicine, Dong-eui Oriental University Hospital. Medical records of inpatinets who underwent facial ENoG, NET test were analyzed. Changes of HBGS grade and Yanagihara's score were also evaluated. We classified inpaients acording to Sasang constitution by consulting to Department of Sasang constitutinal medicine, and to Hyungsang classification(Dam-body, Bangkwang-body) by measuring under medical system of 3D facial shapes(RS-400FL). The constitutional differentiation and general characteristics were initially analyzed, and valuse on ENoG, NET were correlated with constitutinal differentiation. Results of HBGS and Yanagihara's score were also correlated with constitutinal differentiation. Results : 1. Each 39.2 percent of idiopathic facial palsy inpatients were the Taeeumin and Soyangin, 21.6 percent were the Soeumin. 2. 75.5 percent of idiopathic facial palsy inpatients were the Bangkwang-body, 24.5 percent were the Dam-body. 3. 34.3 percent of idiopathic facial palsy inpatinets were the Taeeum-Bangkwang, 21.6 percent were the Soyang-Bangkwang, 19.6 percent were the Soeum-Bangkwang, 17.6 percent were the Soyang-Dam, 4.9 percent were the Taeem-Dam, 2 percent were the Soeum-Dam. 4. By sex, the each ratio of Taeeumin, Soeumin, Bangkwang-body, Taeeum-Bangkwang, Soeum-Bangkwang, Soyang-Bangkwang was higher in female, that of Dam-body, Taeeum-Dam, Soyang-Dam was higher in male. 5. By relations between Sasang constitution and Hyungsang classification, the each ratio of Taeeumin and Soeumin was higher in Bangkwang-body. 6. By values on ENoG and NET, evaluations of HBGS's grade and Yanagihara's score, there were no significant difference. Conclusions : In idiopathic facial palsy inpatients, the proportion of Taeeum and Soyang among the Sasang constitution was higher, that of Dam among the Hyungsang classification was higher, that of Taeeum-Bangkwang among the Sasang combined with Hyungsang was the highest. It would seem that Bangkwang-body, female were closely related to Taeeumin, Soeumin. Also, Dam-body were closely related to male. But when comparing groups, there was no statistically significant difference in prognosis and improvement.