• 한국전자통신학회논문지
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• 제17권6호
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• pp.1089-1094
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• 2022

본 논문에서는 일상생활에서 사람과 교감하며 돌봄 인력의 공백을 완화할 수 있는 인간 공존형 반려 로봇을 연구하였다. 음성인식 모듈과 서보모터, 아두이노 보드를 기반으로 음성인식을 이용한 로봇팔 제어기능, RC카를 활용한 위치 이동 기능, 음성인식 기능을 활용하여 도트 매트릭스를 이용한 반려 로봇의 감정표현 기능을 탑재한 반려 로봇을 실험, 제작하였다. 실험 결과로 거리에 따른 음성인식 실험 결과 5~30cm의 거리에서 최적의 인식률을 보였고 성별에 따른 음성인식 실험 결과에서는 남성의 인식률이 더 높은 것을 확인할 수 있었으며 성조에 따른 음성인식 실험 결과 첫 번째 성조인 단조로운 톤에서 높은 인식률을 보였다. 이러한 동작 실험에 대한 평가 결과를 통해 반려 로봇을 만들 수 있음을 확인할 수 있었다.

• Journal of Periodontal and Implant Science
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• 제53권1호
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• pp.20-37
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• 2023

Purpose: Our pilot study showed that a 3-dimensional dual drug delivery scaffold (DDDS) loaded with Chinese herbs significantly increased the regenerated bone volume fraction. This study aimed to confirm the synergistic anti-inflammatory and osteogenic preclinical effects of this system. Methods: The targets and pathways of parthenolide and naringin were predicted. Three cell models were used to assess the anti-inflammatory effects of parthenolide and the osteogenic effects of naringin. First, the distance between the cementoenamel junction and alveolar bone crest (CEJ-ABC) and the bone mineral density (BMD) of surgical defects were measured in a rat model of periodontitis with periodontal fenestration defects. Additionally, the mRNA expression levels of matrix metallopeptidase 9 (MMP9) and alkaline phosphatase (ALP) were measured. Furthermore, the number of inflammatory cells and osteoclasts, as well as the protein expression levels of tumor necrosis factor-alpha (TNF-α) and levels of ALP were determined. Results: Target prediction suggested prostaglandin peroxidase synthase (PTGS2) as a potential target of parthenolide, while cytochrome P450 family 19 subfamily A1 (CYP19A1) and taste 2 receptor member 31 (TAS2R31) were potential targets of naringin. Parthenolide mainly targeted inflammation-related pathways, while naringin participated in steroid hormone synthesis and taste transduction. In vitro experiments revealed significant antiinflammatory effects of parthenolide on RAW264.7 cells, and significant osteogenic effects of naringin on bone marrow mesenchymal stem cells and MC3T3-E1 cells. DDDS loaded with parthenolide and naringin decreased the CEJ-ABC distance and increased BMD and ALP levels in a time-dependent manner. Inflammation was significantly alleviated after 14 days of DDDS treatment. Additionally, after 56 days, the DDDS group exhibited the highest BMD and ALP levels. Conclusions: DDDS loaded with parthenolide and naringin in a rat model achieved significant synergistic anti-inflammatory and osteogenic effects, providing powerful preclinical evidence.

• 반도체디스플레이기술학회지
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• 제22권3호
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• pp.28-35
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• 2023

Moiré patterns emerge due to the interference between the non-emission area of the LED screen and the grid line in an image sensor of a video recording device when taking a video in the presence of the LED screen. To reduce the moiré intensity, we have fabricated an anti-moiré filter using hollow glass microspheres (HGMs) by slot-die coating. The LED screen has a large non-emission area because of a large pitch (distance between LED chips), causing more severe moiré phenomenon, compared with a display panel having a very narrow black matrix (BM). It is shown that HGMs diffuse light in such a way that the periodicity of the screen is broken and thus the moiré intensity weakens. To quantitatively analyze its moiré suppression capability, we have calculated the spatial frequencies of the moiré fringes using fast Fourier transform. It is addressed that the moiré phenomenon is suppressed and thus the amplitude of each discrete spatial frequency term is reduced as the HGM concentration is increased. Using the filter with the HGM concentration of 9 wt%, the moiré fringes appeared depending sensitively on the distance between the LED screen and the camera are almost completely removed and the visibility of a nature image is enhanced at a sacrifice of luminance.

• 한국어류학회지
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• 제17권3호
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• pp.173-186
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• 2005

한국과 대서양산 갈치 (Trichiurus lepturus) 2지리적 집단으로부터 genomic DNA를 분리 추출하였다. 선택된 8개의 RAPD primer를 이용하여 common, polymorphic 그리고 specific fragment를 얻어냈다. 2지역으로부터 primer간 banding patterns 의 복잡성이 두드러지게 나타났다. DNA fragment 의 분자적 크기는 150 bp에서부터 3,000 bp까지 커다란 차이를 나타내었다. 본 연구에서 한국산 갈치 집단에서는 947개의 fragment가 나타났고, 대서양산 갈치 집단에서는 642개의 fragment 가 확인되었다. 또한 한국산 집단에서는 148개의 specific fragment (15.6%) 가 확인되었으며, 대서양산 갈치집단에서는 61개의 specific fragment (9.5%)가 발생되었다. 한국산 갈치집단에서는 638개의 common fragment가 나타났으며, 이는 primer 당 평균적으로 79.8개의 fragment 로 확인되었다. 또한 대서양산 갈치집단에서는 429개의 common fragment 가 확인되었고, 평균해서 primer 당 53.6개의 common fragment 가 나타났다. 한국산 갈치집단과 대서양산 갈치집단의 polymorphic fragment는 각각 76개와 27개로 확인되었다. 모든 갈치시료의 평균적인 bandsharing value를 기초로 해서 한국산 갈치집단의 similarity matrix를 조사해 본 결과 0.784 로부터 0.922까지 나타났고, 대서양산 갈치집단의 값은 0.833로부터 0.990까지 확인되었다. 결과적으로 대서양산 갈치집단내 개체의 bandsharing value 평균값은 한국산 갈치집단의 평균값보다 높게 나타났다. 8개의 primer를 사용하여 얻어진 dendrogram은 cluster 1 (KOREAN 01~KOREAN 11) 및cluster 2 (ATLANTIC 12~ATLANTIC 22)와 같이 2개의 유전적 클러스터로 나뉘어졌다. 한국산 갈치집단내의 10번째 개체(KOREAN no. 10)와 11번째 개체(KOREAN no. 11) 사이가 가장 가까운 유전적 관계(genetic distance = 0.038)를 나타내었다. 궁극적으로 볼 때 한국산 갈치집단의 1번째(KOREAN no. 01)와 대서양산 갈치집단의 16번째(ATLANTIC no. 16) 개체 사이가 가장 먼 유전적 거리(genetic distance = 0.708)를 나타내었다.

• Asian-Australasian Journal of Animal Sciences
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• 제21권5호
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• pp.617-623
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• 2008

A fine-mapping method exploiting linkage disequilibrium was used to detect quantitative trait loci (QTL) on the X chromosome affecting milk production, body conformation and productivity traits. The pedigree comprised 22 paternal half-sib families of Black-and-White Holstein bulls in the Netherlands in a grand-daughter design for a total of 955 sons. Twenty-five microsatellite markers were genotyped to construct a linkage map on the chromosome X spanning 170 Haldane cM with an average inter-marker distance of 7.1 cM. A covariance matrix including elements about identical-by-descent probabilities between haplotypes regarding QTL allele effects was incorporated into the animal model, and a restricted maximum-likelihood method was applied for the presence of QTL using the LDVCM program. Significance thresholds were obtained by permuting haplotypes to phenotypes and by using a false discovery rate procedure. Seven QTL responsible for conformation types (teat length, rump width, rear leg set, angularity and fore udder attachment), behavior (temperament) and a mixture of production and health (durable prestation) were detected at the suggestive level. Some QTL affecting teat length, rump width, durable prestation and rear leg set had small numbers of haplotype clusters, which may indicate good classification of alleles for causal genes or markers that are tightly associated with the causal mutation. However, higher maker density is required to better refine the QTL position and to better characterize functionally distinct haplotypes which will provide information to find causal genes for the traits.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제10권8호
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• pp.3806-3825
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• 2016

This paper brings out a neoteric frame of reference for visual semantic based 3d video search and retrieval applications. Newfangled 3D retrieval application spotlight on shape analysis like object matching, classification and retrieval not only sticking up entirely with video retrieval. In this ambit, we delve into 3D-CBVR (Content Based Video Retrieval) concept for the first time. For this purpose we intent to hitch on BOVW and Mapreduce in 3D framework. Here, we tried to coalesce shape, color and texture for feature extraction. For this purpose, we have used combination of geometric & topological features for shape and 3D co-occurrence matrix for color and texture. After thriving extraction of local descriptors, TB-PCT (Threshold Based- Predictive Clustering Tree) algorithm is used to generate visual codebook. Further, matching is performed using soft weighting scheme with L₂ distance function. As a final step, retrieved results are ranked according to the Index value and produce results .In order to handle prodigious amount of data and Efficacious retrieval, we have incorporated HDFS in our Intellection. Using 3D video dataset, we fiture the performance of our proposed system which can pan out that the proposed work gives meticulous result and also reduce the time intricacy.

• International Journal of Aeronautical and Space Sciences
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• 제16권2호
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• pp.278-294
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• 2015

Considering the guidance and control problem of the near space interceptor (NSI) during the terminal course, this paper proposes a three-channel independent integrated guidance and control (IGC) scheme based on the backstepping sliding mode and finite time disturbance observer (FTDO). Initially, the three-channel independent IGC model is constructed based on the interceptor-target relative motion and nonlinear dynamic model of the interceptor, in which the channel coupling term and external disturbance are regarded as the total disturbances of the corresponding channel. Then, the FTDO is introduced to estimate the target acceleration and control system loop disturbances, and the feed-forward compensation term based on the estimated values is employed to effectively remove the effect of disturbances in finite time. Subsequently, the IGC algorithm based on the backstepping sliding mode is also given to obtain the virtual control moment. Furthermore, a robust least-squares weighted control allocation (RLSWCA) algorithm is employed to distribute the previous virtual control moment among the corresponding aerodynamic fins and reaction jets, which also takes into account the uncertainty in the control effectiveness matrix. Finally, simulation results show that the proposed IGC method can obtain the small miss distance and smooth interceptor trajectories.

• 한국컴퓨터산업학회논문지
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• 제7권5호
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• pp.537-544
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• 2006

최근 대용량의 디지털 이미지가 제작되면서 멀티미디어 관련 기술에서 이미지 검색이 많은 관심의 대상이 되고 있다. 본 논문에서는 이미지 검색(Image Search)을 위한 가장 기본적인 요소인 이미지 색상에 칼라 분포 정보를 이용하고 다양한 요소에 따라 가중치를 부여한 칼라 기반의 검색 기술자(Descriptor)를 제안하였고 시뮬레이션을 통하여 제안 기술자의 성능을 평가하였다. 칼라 히스토그램을 통한 이미지 검색 기술자를 설계하는데 있어 칼라모델은 HSV를, 웨이블릿 변환 필터는 Daubechies 9/7을, 웨이블릿 분해 레벨은 2레벨을 적용하였을 때 가장 좋은 검색 효율성을 보였다. 또한 유사도 검색은 히스토그램 이차행렬(Quadratic Matrix)을 적용하여 보다 나은 성능을 얻었으나 유사도 검색 계산 시간에서 절대 차이값의 합(L1 Norm)을 사용하는 경우에 비해 20배 이상의 처리 시간이 소요되었다.

• Molecules and Cells
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• 제27권6호
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• pp.629-634
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• 2009

G protein-coupled receptors (GPCRs) are part of multi-protein networks called 'receptosomes'. These GPCR interacting proteins (GIPs) in the receptosomes control the targeting, trafficking and signaling of GPCRs. PDZ domain proteins constitute the largest protein family among the GIPs, and the predominant function of the PDZ domain proteins is to assemble signaling pathway components into close proximity by recognition of the last four C-terminal amino acids of GPCRs. We present here a machine learning based approach for the identification of GPCR-binding PDZ domain proteins. In order to characterize the network of interactions between amino acid residues that contribute to the stability of the PDZ domain-ligand complex and to encode the complex into a feature vector, amino acid contact matrices and physicochemical distance matrix were constructed and adopted. This novel machine learning based method displayed high performance for the identification of PDZ domain-ligand interactions and allowed the identification of novel GPCR-PDZ domain protein interactions.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2005년도 춘계학술대회 논문집
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• pp.749-752
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• 2005

In the industry, three-dimensional coloring has been needed for realistic prototype from rapid prototyping. Z-corporation developed a 3D printer which provides three-dimensional colored prototype. However, the existing process cannot be adopted to models from other rapid prototyping process. In addition, time and cost for manufacturing colored prototype still remain to be improved. In this study, a new coloring process using ink-jet head is proposed for color printing on three-dimensional prototype surface. Process parameters such as the angle and the distance between ink-jet nozzle and the three-dimensional surface should be investigated from experiments. The correction matrix according to sloped angle to minimize the distortion of 2D image was proposed by analysis of printing error. Therefore, approximated method for angle and discrete length according to the radius of curvature for printing on the curved surface was proposed. By printing image on the doubly curved surface, the method was verified. As a practical example, helmet was chosen for printing images on the curved surface. The character images were applied with approximated method for angle and discrete length and was printed on the helmet surface.