• Title/Summary/Keyword: Distance Geometry

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Solution State Structure of pA1, the Mimotopic Peptide of Apolipoprotein A-I, by NMR Spectroscopy

  • Kim, Hyo-Joon;Won, Ho-Shik
    • Bulletin of the Korean Chemical Society
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    • v.32 no.9
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    • pp.3425-3428
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    • 2011
  • Apolipoprotein A-I (Apo A-I) is a major component for high density lipoproteins (HDL). A number of mimetic peptides of Apo A-I were screened from the phase-displayed random peptide library by utilizing monoclonal antibodies (A12). Mimetic peptide for A12 epitope against Apo A-I was selected as CPFARLPVEHHDVVGL (pA1). From the BLAST search, the mimetic peptide pA1 had 40% homology with Apo A-I. As a result of the structural determination of this mimotope using homo/hetero nuclear 2D-NMR techniques and NMR-based distance geometry (DG)/molecular dynamic (MD) computations, DG structure had low penalty value of 0.3-0.7 ${\AA}^2$ and the total RMSD was 0.6-1.6 ${\AA}$. The mimotope pA1 exhibited characteristic conformation including a ${\beta}$-turn from Pro[7] to His[11].

Electric Field Effect on Nanochannel Formation in Electrochemical Porous Structures of Alumina

  • Kim, Keun-Joo;Choi, Jae-Ho;Lee, Jung-Tack
    • Transactions on Electrical and Electronic Materials
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    • v.11 no.5
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    • pp.230-233
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    • 2010
  • The authors investigated the anodization mechanism of aluminum in an oxalic acid solution, and the electrochemical reaction is very unique for pore formation via the dissolution process, which is very dependent on the surface geometry in nanoporous alumina templates. The cross-sectional nanochannels showed that the geometrical curvature of the initial surface can cause the branching of nanochannels to be adjusted in volume occupancy to be direct to the electric field normal to the surface. The nanoporous alumina with the crystalline $\gamma-Al_2O_3$ phase showed hexagonal ordering at a voltage of 40 V, with a nanohole distance of 102 nm from the charge density oscillation of the oxalic acid solution.

A Study on the Characteristics of an Oscillating Fluidic Atomizer

  • Kim, K.H.;Kiger, K.;Lee, W.
    • Journal of ILASS-Korea
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    • v.11 no.2
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    • pp.105-112
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    • 2006
  • A unique feature of fluidic atomizers is that the nozzle geometry produces a thin capillary Jet which is forced to oscillate on a 2-dimensional plane through the use of a passive feedback mechanism. The objective of the current work is to characterize the influence of the stagnation pressure at the nozzle exit, jet oscillation and stretching on the breakup properties of the capillary ligament. To achieve this, shadow graph technique is used to measure size, shape, velocity and the number density of the droplets as a function of the position within the spray fan. The breakup length, defined as the radial distance from the breakup point, is analyzed as a function of the non-dimensional parameters. Finally, a kinematic model is developed to simulate the breakup of the oscillating jets at low stagnation pressures. Using the existing jet breakup theories, the model is used to predict the size and diameter distribution of the droplets after primary atomization.

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Parallel Genetic Algorithm based on a Multiprocessor System FIN and Its Application to a Classifier Machine

  • 한명묵
    • Journal of the Korean Institute of Intelligent Systems
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    • v.8 no.5
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    • pp.61-71
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    • 1998
  • Genetic Algorithm(GA) is a method of approaching optimization problems by modeling and simulating the biological evolution. GA needs large time-consuming, so ti had better do on a parallel computer architecture. Our proposed system has a VLSI-oriented interconnection network, which is constructed from a viewpoint of fractal geometry, so that self-similarity is considered in its configuration. The approach to Parallel Genetic Algorithm(PGA) on our proposed system is explained, and then, we construct the classifier system such that the set of samples is classified into weveral classes based on the features of each sample. In the process of designing the classifier system, We have applied PGA to the Traveling Salesman Problem and classified the sample set in the Euclidean space into several categories with a measure of the distance.

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A Computerized Design System of the Axial Fan Considering Performance and Noise Characteristics (성능 및 소음특성을 고려한 축류 팬 설계의 전산 체계)

  • Lee, Chan;Kil, Hyun-Gwon
    • The KSFM Journal of Fluid Machinery
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    • v.13 no.2
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    • pp.48-53
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    • 2010
  • A computerized design system of axial fan is developed for constructing 3-D blade geometry and predicting both aerodynamic performance and noise. The aerodynamic blading design of fan is conducted by blade angle distribution, camber line determination, airfoil thickness distribution and blade element stacking along spanwise distance. The internal flow and the aerodynamic performance of designed fan are predicted by the through-flow modeling technique with flow deviation and pressure loss correlations. Based on the predicted internal flow field and performance data, fan noise is predicted by two models for discrete frequency and broadband noise sources. The present predictions of the flow distribution, the performance and the noise level of actual fans are well agreed with measurement results.

Kinematics and Control of a Visual Alignment System for Flat Panel Displays (평판 디스플레이 비전 정렬 시스템의 기구학 및 제어)

  • Kwon, Sang-Joo;Park, Chan-Sik;Lee, Sang-Moo
    • Journal of Institute of Control, Robotics and Systems
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    • v.14 no.4
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    • pp.369-375
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    • 2008
  • The kinematics and control problem of a visual alignment system is investigated, which plays a crucial role in the fabrication process of flat panel displays. The first solution is the inverse kinematics of a 4PPR parallel alignment mechanism. It determines the driving distance of each joint to compensate the misalignment between mask and panel. Second, an efficient vision algorithm for fast alignment mark recognition is suggested, where by extracting essential feature points to represent the geometry of a mark, the geometric template matching enables much faster object recognition comparing with the general template matching. Finally, the overall visual alignment process including the kinematic solution, vision algorithm, and joint control is implemented and experimental results are given.

The fragmented asteroid 354P/LINEAR (2010 A2) captured by the K-GMT science program

  • Kim, Yoonyoung;Ishiguro, Masateru;Lee, Myung Gyoon
    • The Bulletin of The Korean Astronomical Society
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    • v.42 no.2
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    • pp.49.2-49.2
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    • 2017
  • With support from the K-GMT science program (PID: GN-2016B-Q-14), we conducted observations of active asteroid 354P/LINEAR (2010 A2) when it made its closest approach to Earth (i.e., the geocentric distance of 1.06 au on 2017 January 27-28). Taking advantage of the best observing geometry since the discovery, we obtained the first evidence for the rotational status of the largest fragment (~120 m in diameter), which was slowly rotating, that is, the rotational period of 11.36 hours. In addition, we succeed in direct imaging of 10 sub-fragments (~20 m in diameter or larger). Based on these new observational results, we conjecture that this active asteroid was created as a result of catastrophic collision among unknown asteroids. The details of this work are given in Astrophysical Journal Letters, 842, L23.

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A Study on Improvement of the Measurement Method for Optical Scanner (광학식 스케너의 측정방법 개선에 관한 연구)

  • Joo, M.S.;Kim, M.J.;Lee, S.S.;Kim, S.K.;Jeon, E.C.
    • Proceedings of the KSME Conference
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    • 2001.11a
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    • pp.841-847
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    • 2001
  • This study is on the precision of the optical scanner which is suitable for shape modeling and non-contact equipment, comparing with a razer scanner. The optical scanner not only has all merits that non-contact methods have but also improve a veil phenomenon which is a razer scanner's demerits. However, the optical scanner has not been used extensively because the measurements are not very precise and there are not the definite methods of measurement. Hence, this study is to find out how parameters such as camera's hight, angle, luminous intensity, distance to object, and so on have an influence on measuring using the optical scanner and to establish the methods of measuring precision.

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Effect of nozzle geometry on the jet impingement heat transfer characteristics at protruding heated blocks (노즐형상에 따른 돌출 발열블록표면에서의 충돌분류 열전달 특성)

  • Chung, In-Kee;Park, Si-Woo
    • Proceedings of the KSME Conference
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    • 2000.11b
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    • pp.93-98
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    • 2000
  • An experimental investigation on heat transfer characteristics of two-dimensional heated blocks using a confined impinging slot jet has been performed. At p/w=1, the effects of jet Reynolds number($Re=3900{\sim}12000$), dimensionless nozzle to block distance(H/B=1, 2, 4, 6) and nozzle type have been examined with five isothermally heated blocks. With the measurement of jet mean velocity and turbulence intensity distributions at nozzle exit, initially turbulent regimes, are classified. To clarify local heat transfer characteristics, naphthalene sublimation technique were used. The local and average heat transfer of heated blocks increase with the sharp-edged nozzle and increasing jet Reynolds number.

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Effect of nozzle geometry on heat transfer of confined slot jet impingement on a flat plate with square rods (사각봉이 배열된 슬롯제트 충돌면에서 노즐형상이 열전달에 미치는 영향)

  • Chung, In-Kee;Park, Si-Woo;Ko, Wan-Wook
    • Proceedings of the KSME Conference
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    • 2000.11b
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    • pp.272-277
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    • 2000
  • The heat transfer characteristics of confined turbulent slot jet impingement on the flat plate with square rods(turbulence promoter) have been experimentally investigated at different nozzle configuration. The effects of jet Reynolds number (Re=3900, 5800, 7800, 9700), dimensionless slot-to-plate distance(H/B=4, 6, 8) and clearance(c) between square rods and the plate were examined. Measurement of heat transfer rate were conducted using naphthalene sublimation technique. When square rods were inserted over the heat transfer surface, heat transfer rate was slightly increased in the wall jet region and the sharp-edged orifice nozzle was heigher than squared orifice nozzle.

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