• 한국산업정보학회논문지
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• 제26권3호
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• pp.9-22
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• 2021

본 연구에서는 조립산업의 공급망(Supply chain)에서의 발생할 수 있는 공급붕괴(Supply disruption)를 고려한 공급망 네트워크(Supply chain network: SCN) 모델이 제안된다. 공급붕괴를 위해 공급자 붕괴(Supplier disruption)와 경로 붕괴(Route disruption)가 함께 SCN 모델에서 고려되며, 이러한 두 가지의 붕괴 현상을 함께 고려한 SCN 모델은 유연성(Flexibility)과 효율성(Efficiency)을 성취할 수 있게 된다. SCN 모델은 수리모형으로 표현되며, 혼합유전알고리즘(Proposed hybrid genetic algorithm: pro-HGA) 접근법을 이용해 이행된다. 수치실험에서는 몇몇 상이한 규모를 가진 SCN 모델을 이용해 제안된 pro-HGA 접근법의 수행도와 기존 접근법의 수행도를 비교분석하였으며, 공급자 수와 백업경로(Backup route) 수의 변화를 통한 민감도 분석을 실시하였다. 실험 결과, 제안된 pro-HGA 접근법의 효율성을 입증하였고, SCN 모델의 유연성과 효용성을 검증하였다. 마지막으로 본 연구 수행의 의의 및 향후 개선방향에 대해 논하였다.

• 품질경영학회지
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• 제52권2호
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• pp.221-239
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• 2024

Purpose: This study explores how supplier and customer integration impact a firm's disruption absorption capability, with a focus on IT alignment moderation. Methods: We conducted surveys with 296 Chinese manufacturers and utilized hierarchical regression for analysis. Results: : Our results reveal a positive correlation between supplier/customer integration and disruption absorption capability. Additionally, positive IT alignment bolsters the relationship between supplier integration and disruption absorption capability, while it doesn't affect the link between customer integration and disruption absorption capability. Conclusion: These findings underscore the significance of integration and IT alignment for enhancing a firm's disruption absorption capability, providing crucial insights for supply chain management practitioners.

• 한국기계가공학회지
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• 제20권8호
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• pp.33-41
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• 2021

Recently, many studies have been conducted on substituting fossil fuels with bio-refineries in existing industrial systems using biomass. Among the various bio-refineries, microalgae have received wide attention because it uses inorganic compounds to produce useful substances, which are extracted by a cell disruption process. Although numerous cell disruption methods exist, cell disruption efficiency has been studied by ultrasonic treatment. Ultrasound is a high-frequency (20 kHz or higher) sound wave and causes cell disruption by cavitation when passing through a solvent. In this study, we used the microalgal species Chlorella sp., which was cultured in a plate-type photobioreactor. The experiment was conducted using a continuous low-frequency processing device. The reduction of cells with time due to cell disruption was fitted using a logistic model, and optimum conditions for highly efficient cell disruption were determined by conducting experiments under multiple conditions.

• 한국환경보건학회지
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• 제39권1호
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• pp.1-18
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• 2013

Objectives: Although a great body of knowledge is available on the toxicity of bisphenol A (BPA), little is known about that of BPA alternatives, such as bisphenol analogues (BPs) or $Tritan^{TM}$ copolyesters. This review provides a summary of the available information on the toxicity of BPs and three components of $Tritan^{TM}$, with a special focus on endocrine disruption. Methods: We collected from the literature a battery of in vitro and in vivo assay data developed to assess endocrine disruption of four BPs (bisphenol AF, B, F, and S) and three major components of $Tritan^{TM}$ ((di-methylterephthalate (DMT), 1,4-cyclohexanedimethanol (CHDM), and 2,2,4,4-tetramethyl-1,3-cyclobutanediol (TMCD)). Results: Several alternative compounds were identified as possessing comparable or even greater endocrinedisrupting effects than BPA in in vitro and in vivo studies. Conclusions: Potential endocrine disruption of BPA alternatives requires further studies on health consequences in experimental animals and in humans following longer term exposure.

• 유통과학연구
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• 제18권11호
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• pp.91-103
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• 2020

The recent Covid-19 outbreak has caused severe disruption of the global supply chain, which tests firms' ability to survive and build resilience. The concept of adaptive supply chain management (A-SCM) has never been tested against a severe supply chain disruption, such as a pandemic. Purpose: The aim of this study is to examine how firms in Indonesia develop resilience through the implementation of components of adaptive supply chain management, namely risk management, resource reconfiguration and supply chain flexibility, in order to survive severe supply chain disruption. Research design, data and methodology: A qualitative method and PLS-SEM were used to analyze 120 data collected from Indonesian manufacturing firms in various industries. Results: The findings show that risk management, resource reconfiguration, and supply chain flexibility are important components that make up A-SCM. However, only risk management contributes to help build firm resilience in the presence of severe supply chain disruption. Conclusions: The components of A-SCM have been empirically tested. The implication is that managers should carefully use RM to prepare firms for different scenarios to develop contingency strategies. This research contributes to the supply chain management body of knowledge in the context of pandemic-level disruption and broadens the dynamic capabilities perspective.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2002년도 Current Trends in Toxicological Sciences
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• pp.132-132
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• 2002

Effects of antioxidant vitamins were investigated in di(2-ethylhexyl) phthalate (DEHP)-induced endocrine disruption toxicity. After rats were treated with DEHP, and vitamin C and vitamin E were supplemented for 30 days.(omitted)

• 한국기계가공학회지
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• 제19권2호
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• pp.111-118
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• 2020

Recently, bioenergy research using microalgae, one of the most promising biofuel sources, has attracted much attention. Cell disruption, which can be classified as physical or chemical, is essential to extract functional ingredients from microalgae. In this study, we investigated the cell disruption efficiency of Chlorella sp. using low-frequency non-focused ultrasound (LFNFU). This is a continuously physical method that is superior to chemical methods with respect to environmental friendliness and low processing cost. A flat panel photobioreactor was employed to cultivate Chlorella sp. and its growth curve was fitted both with Logistic and Gompertz models. The temporal change in cell reduction by cell disruption using LFNFU was fitted with a Logistic model. The experimental conditions that were investigated were the initial concentration of microalgal cells, relative amplitude of output ultrasound waves, processing volume of microalgal cells, and initial pH value. The optimal conditions for the most efficient cell disruption were determined through the various tests.

• 성인간호학회지
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• 제17권2호
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• pp.310-319
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• 2005

Purpose: The purpose of the study is to investigate the degree of fatigue and its related factors in patients with breast cancer. Method: The subjects of this study consisted of 62 breast cancer patients receiving chemotherapy. The Revised Piper Fatigue Scale, Disruption of Usual Activity Scale, Linear Analogue Self Assessment Scale and Self-Care Diary Scale were employed to measure fatigue, disruption of usual activity, mood state and physical symptom respectively. Collected data were analyzed using SPSS-PC to obtain summary statistics for the descriptive analysis, Pearson Correlation, and Stepwise Multiple Regression. Result: The results are as follows. 1. The mean score of the degree of fatigue was 4.82 points indicating moderate level. 2. The mean score of the degree of disruption of usual activity, mood state and physical symptom were 2.66, 5.00, and 4.69 points. 3. Fatigue of the subjects was significantly correlated with disruption of usual activity(r=.517, p<.01), mood state(r=.420, p<.01) and physical symptom(r=.463, p<.01). 4. With the result of stepwise multiple regression, disruption of usual activity, mood state and physical symptom being the three variables which could explain fatigue by 39.1%. The results of this study suggest that comprehensive intervention strategy for fatigue should be developed to maintain quality of life during and following chemotherapy considering these factors.

• Journal of Yeungnam Medical Science
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• 제8권1호
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• pp.238-245
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• 1991

추간판 내부 파열 증후군은 심한 요통, 하족부 동통, 에너지 소실, 체중감소, 그리고 심한 우울증을 동반하며 척추 단순 촬영, 척수강 조영술, 전산화 단층 촬영, 혈액 검사, 그리고 신경학적 검사에서 이상소견을 발견할 수 없고 추간원판 조영술 상에서만 이상소견 및 동통의 증가로 진단이 가능한 증후군으로 알려져 있다. 저자들은 요통을 주소로 내원한 환자들 중 2례에서 추간판 내부 파열 증후군으로 진단되어 수술적 치료 후 만족할 만한 결과를 얻었기에 문헌고찰과 함께 보고하는 바이다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권16호
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• pp.6547-6552
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• 2014

Background: Cancer is a major life event that imposes huge economic and mental burdens on patients and families. In addition, the diagnosis of cancer also causes significant family discordance that can lead to marital problems such as divorce or separation. The aim of this study was to investigate the association and any related gender differences between cancer diagnosis and marital disruption among cancer survivors. Materials and Methods: We used the recent cross-sectional Korea National Health and Nutrition Examination Survey ($4^{th}$ and $5^{th}$; Years 2008-2012). The study participants were 623 married cancer survivors over the age of 19. A multivariate logistic regression analysis was conducted to estimate odds ratios. Results: After adjusting for socioeconomic status and health-related behaviors, the odds ratio of marital disruption among female cancer survivors compared with male cancer survivors was 3.94 (95%CI 1.30-11.94; p=0.02). The odds ratio of marital disruption for the below-average economic level compared with the above-average economic level was 5.64 (95%CI: 1.03-31.02; p=0.05). When compared with the non-smoking cancer survivors, the smoking cancer survivors had an OR of marital disruption equal to 2.94 (95%CI: 1.08-8.00; p=0.03). Conclusions: The findings of this study suggest that the odds of marital disruption among female cancer survivors are higher than those among their male couterparts. Medical practitioners should be sensitive to early signs of marital discord in couples affected by a cancer diagnosis. Early identification and psychosocial intervention might reduce the frequency of divorce and separation and thus improve quality of life and quality of care for cancer survivors.