• Journal of Pharmaceutical Investigation
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• v.18 no.2
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• pp.55-59
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• 1988

The size of furosemide was reduced by the recrystallization method in order to increase the dissolution rate of the drug. Surfactants or hydrophilic polymers were used to suppress the aggregation in the crystal formation-growth process of microparticles by dispersing action. Dissolution rate of microparticles increased remarkably due to the size reduction of microparticle. The particle size decreased with increasing the concentration of the drug and the dispersing agents, i.e., surfactants or hydrophilic polymers. No polymorphic transition occurred during the microcrystallization process, but the habit of crystal formation was altered in the case of anionic surfactant.

• Proceedings of the KSME Conference
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• 2007.05a
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• pp.37-42
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• 2007

We present a powder injection molding technique of fabricating cemented tungsten carbide(WC) balls for milling and dispersing nano-powder in this paper. The conventional powder metallurgy approach is investigated to reveal its drawbacks of density non-homogeneity. New procedures of powder injection molding for the homogeneous high-precision WC balls, involving the binding process, powder injection molding process and sintering process, are presented in detail. Each process is investigated empirically and numerically to obtain its engineering information, which can used for process optimization.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2006.11a
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• pp.384-385
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• 2006

We studied about conductive pastes of the source-drain contacts for OTFTs(organic thin-film transistors) fabricated by direct printing(screen printing) method. We used Ag and conductive carbon black powder as the conductive fillers of pastes. The conductive pastes were manufactured by various dispersing agents and dispersing conditions and source-drain contacts with $100{\mu}m$ of channel length were fabricated. We could obtain the OTFTs which exhibited different field-effect behaviors over a range of source-dram and gate voltages depending on a kind of conductive fillers used conductive pastes.

• YAKHAK HOEJI
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• v.34 no.3
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• pp.199-205
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• 1990

Microencapsulation of nalidixic acid using Eudragit RL, a methacrylic acid copolymer was investigated. Microcapsules were prepared by dispersing the drug solution in liquid paraffing using aluminium tristearate as dispersing agent. The preparation of the microcapsules showed high reprodulibility in particle size, shape and the drug content. The dissolution rates of Nalidixic acid from the these microcapsules considerably decreased as compared with that from Nalidixic acid powder and Nalidixic acid-Eudragit RL solid dispersions. The release of Nalidixic acid increased with increasing percentage of aluminium tristearate added to the microcapsules.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.21 no.2
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• pp.188-193
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• 2008

Epoxy/Organically Modified Layered Silicate Nanocomposites were prepared by dispersing synthetic layered silicate modified with alkyl ammonium ions. In the dispersing process, the organically modified layered silicate were mixed in epoxy resin with shearing, and aggregation of the silicate were removed by centrifugal separation after mixing epoxy resin and silicates. Micrographs taken by transmission electron microscopy(TEM) indicate that the nanocomposites have a mixed morphology including both parallel silicate layers and exfoliated silicate layers area, As the thermal properties, the glass transition temperature of the nanocomposites was shifted to a higher temperature($+6^{\circ}C$)than pure epoxy. Furthermore, dispersion of OMLS will prevented relative permittivity from increasing at a high temperature above the glass transition temperature.

• Textile Coloration and Finishing
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• v.9 no.6
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• pp.68-73
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• 1997

Urea/formaldehyde(UF) and melamine/formaldehyde(MF) microcapsules containing perfume and 2,4,4'-trichlroro-2-hydroxydiphenyl ether(DP) were prepared by the in-situ polymerization using urea and formaldehyde. Effects of dispersing agent, accelerating agent, formaldehyde, agitation speed on the mean diameter of microcapsules were investigated. The diameter of microcapsule was decreased with increasing dispersing agent concentration. A slight increase in the diameter was observed when the concentration of film forming material was increased. The diameter of microcapsule was decreased with increasing agitation speed up to 8,000rpm. The mean diameters of UF microcapsule prepared at 8,000rpm are about 3$\mu$m. A slight decrease in the diameter was observed when the concentration of resorcinol was increased.

• Journal of English Language & Literature
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• v.57 no.6
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• pp.911-938
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• 2011

The present study examined the effect of two variables of task complexity, reasoning demand and time pressure, each from the resourcedirecting and resource-dispersing dimension in Robinson's (2001) framework of task classification. Reasoning demand was operationalized as the two types of texts to read and summarize, expository and argumentative. Time pressure was operationalized as the two modes of performance, oral and written. Six university students summarized the two types of text orally and twenty four students from the same school summarized them in the written form. Results from t test and ANCOVA showed that in the oral mode, reasoning demand tends to heighten the complexity of the language used in the summary in competition with accuracy but such an effect disappeared in the written mode. It was interpreted that the degree of time pressure is not the only difference between the oral and written modes but that the two modes may be fundamentally different cognitive tasks, and that Robinson's (2001) and Skehan's (1998) models were differentially supported by the oral mode of tasks but not by the written mode of the tasks.

• Macromolecular Research
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• v.16 no.8
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• pp.749-752
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• 2008

• Journal of Sasang Constitutional Medicine
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• v.24 no.4
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• pp.1-16
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• 2012

Objectives : We aimed to analyze the meanings of the energy and fluid metabolism in the Discourse on Viscera and Bowels of Donguisusebowon, and to find the clues for the explanation of the pathology and symptomatology of Taeeumin. Methods : The Discourse on Viscera and Bowels of Donguisusebowon was reviewed and examined for relevant information on the energy and fluid metabolism from the structural and the functional point of view respectively. And, based on the derived meanings of the energy and fluid metabolism, the pathology and symptomatology of Taeeumin were analyzed. Results and Conclusions : 1. The meanings of the energy and fluid metabolism can be explained by the different attributes of the energy and fluid produced from the esophagus and the small intestine, and the different function of exhaling-dispersing and inhaling-concentrating in the different tract of circulation such as Lung affiliation (esophagus, skin, ear and lung) and Liver affiliation (small intestine, flesh, nose and liver). 2. The Exterior disease of Taeeumin starts with the weakness of exhaling-dispersing function at the skin, and leads to the dysfunction of the esophagus and the lung sequently. The dysfunction of the lung aggravates that of the skin and the esophagus. 3. The Interior disease of Taeeumin begins with excess of the inhaling-concentrating functions at the flesh and the small intestine, and leads to the dysfunction of the lung, which induces the dysfunction of exhaling-concentration at the skin and esophagus. And, this disparities between exhaling-dispersing and inhaling-concentrating functions exasperate the problem at the flesh and the small intestine.

• YAKHAK HOEJI
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• v.36 no.6
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• pp.598-603
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• 1992

The purpose of this study was to assess the effect of three formulations; product A (polyethylene glycol was used as a main dispersing agent), product B (wax mixture was used as a main dispersing agent) and product C(silicon dioxide was used as a main dispersing agent) on bioavailability of acetaminophen soft gelatin capsules(softgels) and to develop an effective acetaminophen softgel which exhibits an excellent bioavailability. Acetaminophen softgels of various formulations were prepared as 4 minim round type by rotary die method. Four softgels of the three formulation (A, B, C), each of which contained 50 mg acetaminophen, were administered orally to 12 normal healthy rabbits using a three-way cross over design. Plasma acetaminophen concentrations were measured by HPLC. The results obtained in this study were as follows: 1. The Tmax rank order of acetaminophen softgel was C$(63.75{\pm}10.62\;min)$>A$(36.25{\pm}5.37\;min)$>B$(35{\pm}6.74\;min)$. 2. The decreasing Cmax order of softgel product was A$(93.51{\pm}0.55\;{\mu}g/ml)$>B$(3.16{\pm}0.37\;{\mu}g/ml)$>C$(2.6{\pm}0.55\;{\mu}g/ml)$. 3. The $[AUC]^{\infty}_0$ rank order for three acetaminophen softgel formulations was A $(14.89{\pm}1.56\;{\mu}g/ml{\cdot}min)$ >B$(14.39{\pm}1.43\;{\mu}g/ml{\cdot}min)$>C$(11.45{\pm}1.49\;{\mu}g/ml{\cdot}min)$. 4. Pharmacokinetic parameters such as Tmax, Cmax and $[AUC]^{\infty}_0$ of product A and B did not differ significantly(p>0.05). On the other hand, those of product C were significantly different(p>0.05).