• 생물정신의학
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• 제21권2호
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• pp.74-80
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• 2014

Objectives More than half of the elders suffer from chronic sleep disturbances. Moreover, sleep disturbances are more prevalent in patients with depressive disorder than in community dwelling elderly. In this study, we aim to estimate the risk factors of poor sleep quality and its effect on quality of life in patients with late life depression. Methods This study included 159 depressive patients aged 65 years or older who completed Pittsburgh Sleep Quality Index (PSQI). A global PSQI score of 5 or greater indicates a poor sleeper. Structural diagnostic interviews were performed using the Korean version of Mini International Neuropsychiatric Interview (MINI). Depression was evaluated by the Korean form of Geriatric Depression Scale (KGDS). Global cognition was assessed by Mini-Mental State Examination in the Korean version of the Consortium to Establish a Registry for Alzheimer's Disease assessment packet. Quality of life was evaluated by the Korean version of Short-Form 36-Item Health Survey (SF-36). Results The frequencies of poor sleepers were 90.5% in major depressive disorder, 71.8% in minor depressive disorder, 47.1% in subsyndromal depressive disorder, and 73.0% in all types of depressive disorders. Multivariate logistic regression analysis indicated that female [odds ratio (OR) = 2.83, 95% confidence interval (CI) = 1.20-6.67] and higher KGDS score (OR = 1.13, 95% CI = 1.05-1.21) were risk factors of poor sleep quality in patients with late life depression. In the analysis of ANCOVA adjusted for age, gender, education and KGDS score, the mean scores of vitality mental health and mental component summary of SF-36 were lower in poor sleepers than in good sleepers. Conclusions Poor sleepers among patients with late life depression are very common and are associated with female and higher KGDS scores. Poor sleep quality causes a significant negative effect on mental health quality. So researchers and clinicians should be more vigilant in the evaluation and treatment of sleep disturbances in patients with late life depression.

• 경영과정보연구
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• 제36권1호
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• pp.309-327
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• 2017

최근 감정노동의 중요성이 커짐에 따라 본 연구는 감정노동이(표면행동, 내면행동)이 직무소진(정서적 고갈, 탈인격화, 자아성취감 저하)을 매개로 반생산적과업행동(조직일탈, 개인일탈)에 미치는 영향을 검증하고자 한다. 감정노동이 요구되는 콜센터종사자, 백화점판매원, 금융종사자, 병원접점종사자, 호텔접점종사자, 승무원, 고객센터종사자 등을 대상으로 총 350부의 설문지가 배부되었고, 불성실한 응답지를 제외한 300부의 설문지가 분석에 활용되었다. 실증연구결과는 다음과 같다. 첫째, 고객접점 종사자들이 직무수행과정에서 선택하게 되는 감정노동의 유형인 표면행동은 직무소진 중 정서적 고갈, 탈인격화, 자아성취감 저하에 모두 정(+)의 유의한 영향을 미치는 것으로 나타났다. 둘째, 내면행동은 직무소진 중 탈인격화, 자아성취감 저하에 부(-)의 유의한 영향을 미치는 것으로 나타났으나 정서적 고갈에는 유의한 영향을 미치지 않는 것으로 나타났다. 셋째, 직무소진 중 탈인격화와 자아성취감 저하는 모두 반생산적과업행동(조직일탈, 개인일탈)에 모두 정(+)의 유의한 영향을 미치는 것으로 나타났으나 정서적 고갈은 반생산적과업행동(조직일탈, 개인일탈)에 유의한 영향을 미치지 않는 것으로 나타났다. 이러한 분석결과를 토대로 본 연구의 시사점과 한계점 및 향후 연구방향에 대하여 논의하였다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제28권4호
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• pp.244-251
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• 2017

Objectives: The objective of this study was to investigate the effect of pharmacological treatments for attention-deficit hyperactivity disorder (ADHD) on motor coordination, using the Developmental Coordination Disorder Questionnaire (DCDQ). Methods: The participants were recruited from April 2015 to November 2016 from the Department of Psychiatry of Asan Medical Center and were treated for 3 months with methylphenidate or atomoxetine. The illness severity at baseline and 3 months were scored using the ADHD Rating Scale (ARS), Clinical Global Impression-Severity Scale (CGI-S) and/or Clinical Global Impression-Improvement Scale (CGI-I). A total of 39 children with ADHD (age $8.0{\pm}1.4years$, 36 boys) completed the Advanced Test of Attention (ATA) and their parents completed the DCDQ at baseline and 3 months. The paired t-test, mixed between-within analysis of variance and correlation analysis were used. Results: The CGI-S (p<0.001), ARS (p<0.001), and fine motor/hand writing (p=0.005) on the DCDQ were significantly changed between pre-treatment and post-treatment. When the participants were divided into those who were suspected of having developmental coordination disorder (DCD) (n=23) and those who probably did not (n=16), the control during movement, fine motor/hand writing and general coordination scores on the DCDQ showed the main effects for group (p<0.001, p<0.001 and p<0.001, respectively). The fine motor/hand writing on the DCDQ has a significant main effect for time [F(1,37)=7.31, p=0.010, ${\eta}^2=0.405$] and the interaction effect between group and time was also significant [F(1,37)=4.63, p=0.038, ${\eta}^2=0.111$]. The baseline visual commission error on the ATA is significantly correlated with the changes in the DCDQ total scores (r=0.330, p=0.040). Conclusion: Our results provide preliminary evidence that pharmacological treatment for ADHD improves not only the core symptoms of ADHD, but also the motor coordination. Further studies are needed to confirm the effect of the pharmacological treatment for ADHD on the motor coordination.

• 한방재활의학과학회지
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• 제20권4호
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• pp.215-230
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• 2010

Objectives : The purpose of this study is to investigate the effects of aroma therapy on sleep disorder patients with musculoskeletal pain. Methods : The 44 patients were divided into 2 groups: Experimental group(Exp. group) was treated with aroma therapy and control group was treated except aroma therapy. To evaluate the efficiency of aroma therapy, the Korean sleep scale A(Jin-Joo Oh, Mi-Soon Song, Sin-Mi Kim, 1998) and visual analogue scale(VAS) were applied before treatment and after 5 days treatment. Results : 1. The Experimental group has improved statistical significance in sleep disorder score as compare to the control group. 2. The improvement of sleep disorder score of Exp.group has difference according to impression. 3. The improvement of sleep disorder has an effect on pain decrease. Conclusions : Aroma therapy has effects of improvement on sleep disorder with musculoskeletal pain.

• 동의신경정신과학회지
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• 제20권4호
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• pp.79-89
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• 2009

Objectives : To address suitable method for designing clinical trial intervening Traditional Korean Herbal Medicine on General anxiety disorder through the recent clinical research in Chinese Herbal Medicine. Methods : Randomized, controlled trials(RCTs) of treatment of general anxiety disorder intervening herbal medicine were searched through CNKI databases. We examined several item of studies and evaluated using Jadad scale. We searched articles in CNKI with the key word "General anxiety disorder or 廣範性焦慮症", among them we selected the clinical trial studies related with herbal medicine except for case reports, studies of acupuncture therapy or west medicines. Results : 11 RCT studies of herbal medicine met inclusion criteria. The Studies used CCMD-3, HAMA as inclusion tool and mainly HAMA as a evaluation tool. Studies were progressed for 2-8 weeks, mostly used various positive control. Experiment medicine were mainly 理氣劑, 安神劑. In most studies, experiment group made similar or higher efficacy in comparison with control group. Mean Jadad score of studies was $1.3{\pm}0.67$, and only one study was double-blinded among 11 studies. Conclusions : RCT studies on general anxiety disorder of chinese herbal medicine tend to focus on investigating effect of herbal medicine through setting positive control group with CCMD-3 and HAMA. But, most studies had low quality of trial, for lack of pattern identification, evaluation and inclusion tool of chinese medicine. Clinical trials of general anxiety disorder should provide good quality by randomization, double-blinding, and multi-site trial.

• 대한불안의학회지
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• 제11권1호
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• pp.69-74
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• 2015

Objective : Positive psychotherapy is based on the premise that positive thoughts and satisfaction with life are determinants for improving the symptoms of depressive disorder. This article highlights the effectiveness of group positive psychotherapy on the elderly living alone with depressive disorder in Korea. Methods : A total of 25 Korean elderly living alone with depressive disorder participated in group positive psychotherapy. The participants completed the Hamilton rating scale for depression (HAMD) and the Positive Thinking Questionnaire (PTQ) before and after the group positive psychotherapy. Results : The HAMD and PTQ scores of the participants after the group positive psychotherapy were higher than before the psychotherapy. A correlation between the age of patients and improvement of symptoms after group positive psychotherapy was found : the older the patients were, the better the improvements were. Conclusion : The study shows that group positive psychotherapy in the elderly living alone is effective in improving the symptoms of depressive disorder. The participant's age was found to be a factor that affects the improvement of depressive disorder symptoms.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제31권4호
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• pp.207-213
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• 2020

Objectives: Although aggressive behavior in children and adolescents with attention-deficit/hyperactivity disorder (ADHD) has previously shown correlations with hyperactivity/impulsivity, few studies have examined its association with inattention or the effect of working memory on aggressive behavior. This study aimed to assess the relationship between inattention and aggressive behavior and the effect of working memory on the relationship between inattention and aggressive behavior in children and adolescents with ADHD. Methods: Thirty-one children and 26 adolescents with ADHD were retrospectively investigated. The subjects completed the Korean Wechsler Intelligence Scale for Children-Fourth Edition (K-WISC-IV), the Korean Child Behavior Checklist (K-CBCL), and the Korean Children's Depression Inventory (CDI). Results: Inattention was positively correlated with aggressive behavior in children and adolescents with ADHD and working memory showed an insignificant correlation. However, working memory had a significant moderating effect on aggressive behavior by interacting with inattention. The moderating effect of working memory manifested when the working memory index score on the K-WISC-IV was 73.5 points or higher, and it had a significant effect on aggressive behavior. Conclusion: This study shows that the severity of inattention and hyperactivity/impulsivity should be addressed to provide appropriate treatment to children and adolescents with ADHD who exhibit aggressive behavior.

• 한국콘텐츠학회논문지
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• 제21권12호
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• pp.621-631
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• 2021

본 연구는 청소년의 학교폭력 피해 경험이 복합 외상 후 스트레스에 미치는 영향과 이 관계에서 자아존중감의 조절효과를 검증하고자 하였다. 이를 위해 291명의 청소년을 대상으로 조사된 자료를 연구에 활용하였으며, 조절회귀분석을 통해 연구모형을 검증하였다. 연구 결과, 학교폭력 피해 경험과 자아존중감은 복합 외상 후 스트레스에 유의미한 영향을 가진 것으로 나타나 학교폭력 피해 경험의 수준이 높을수록, 자아존중감이 낮을수록 복합 외상 후 스트레스가 증가하게 됨을 확인하였다. 또한 자아존중감은 학교폭력 피해 경험이 복합 외상 후 스트레스에 미치는 영향을 조절하고 있음을 확인하여 같은 수준의 학교폭력 피해 경험이 있더라도 자아존중감이 높은 경우 복합외상 후 스트레스의 문제를 완화할 수 있음을 확인하였다. 연구 결과를 바탕으로 청소년의 학교폭력과 이로 인해 발생하는 복합 외상 후 스트레스의 문제를 완화하기 위한 방안을 제시하였다.

• 대한불안의학회지
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• 제9권1호
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• pp.25-30
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• 2013

공황장애 환자에서 12주간의 escitalopram 약물치료 결과, 공황장애 증상은 관해 상태에 이르렀고, 높은 불안민감도와 삶의 질 저하 및 기능장애가 모두 유의하게 호전되었다. 하지만 공황장애 환자들은 약물치료 후에도 여전히 상대적으로 높은 불안민감도와 삶의 질 저하 및 기능장애를 보여서 이의 회복을 위해서는 장기간의 약물치료가 필요할 수 있겠다.

• 생물정신의학
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• 제4권2호
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• pp.251-258
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• 1997

The dysfunction of either or both noradrenaline and serotonin system are important in the pathophysiology of depression. Previous reports have suggested that there may be an important interaction between these two systems. Recently, some investigators have suggested that the combination of tricyclic antidepressants(TCAs) and selective serotonin reuptake inhibitors(SSRIs) would produce a rapid synergistic effect on down-regulation of either or both of these two systems and that this combination may produce a more rapid and absolute antidepressant effect. We compared the treatment efficacy, treatment associated side effects, treatment satisfaction, and the quality of life between the combination therapy of dothiepin-sertraline as well as the therapy of dothiepin alone in the treatment of major depressive disorder and dysthymic disorder. In our study, the combination therapy of dothiepin and sertraline produced a more rapid and absolute antidepressant effect than dothiepin alone. And the patients with combination therapy experienced relatively high treatment satisfaction than the patients with dothiepin therapy. The patients' quality of life improved more rapidly in the combination therapy, especially, in the health perception, social behavior, and life satisfaction, than dothiepin alone. These results support the hypothesis that the combination of TCA and SSRI may produce a rapid synergistic effect on either or both norepinephrine and serotonin system, and more rapid antidepressant effect and high treatment satisfaction.