• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7431-7434
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• 2015

As an important component of innate immune system, neutrophil has been involved in many other physiological processes, including tumor-related diseases. In 2004, the phenomenon of NETs was reported for the first time. Extracellular decondensed chromatin, released from activated neutrophils, forms a network structure, which is NETs. This review focuses on the function of NETs in tumor cell proliferation, metastasis, and tumor-associated thrombosis; it also explores the application of NETs specific markers in the diagnosis of pre-thrombotic state and tumor associated diseases; it also explores NETs inhibitor for the treatment of tumor-related diseases. In view of the rapid development of NETs, it may provide new therapeutic targets for tumor-associated thrombosis, and even tumor itself.

• Journal of Chest Surgery
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• v.26 no.11
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• pp.874-880
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• 1993

A personal computer, IBM compatible 386, was utilized to analyse total series of 1867 cases of cardiovascular operations including 1060 cases of open cardiac surgeries performed at the Cardiac Center of Paik Hospital from 1986 to 1992.All data were first assembled from the operation files and the operation records from the patient charts. Code numbers were placed to the diagnosis, the operations and the diseases.The analysis revealed the distributions of 1867 cases of operations;819 cases[77%] of the congenital heart diseases and 207 cases[20%] of the acquired heart diseases among 1060 open heart operations. The operative mortalities were 3.7% for the congenital heart diseases and 6.3% for the acquired heart diseases.The vascular operations showed the operative mortalities of 11.8% for the aortic surgery under extracorporeal circulation and 0.7% for the other vascular surgery.

• Korean Journal of Radiology
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• v.24 no.8
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• pp.795-806
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• 2023

Occupational lung diseases (OLD) are a group of preventable conditions caused by noxious inhalation exposure in the workplace. Workers in various industries are at a higher risk of developing OLD. Despite regulations contributing to a decreased incidence, OLD remain among the most frequently diagnosed work-related conditions, contributing to significant morbidity and mortality. A multidisciplinary discussion (MDD) is necessary for a timely diagnosis. Imaging, particularly computed tomography, plays a central role in diagnosing OLD and excluding other inhalational lung diseases. OLD can be broadly classified into fibrotic and non-fibrotic forms. Imaging reflects variable degrees of inflammation and fibrosis involving the airways, parenchyma, and pleura. Common manifestations include classical pneumoconioses, chronic granulomatous diseases (CGD), and small and large airway diseases. Imaging is influenced by the type of inciting exposure. The findings of airway disease may be subtle or solely uncovered upon expiration. High-resolution chest CT, including expiratory-phase imaging, should be performed in all patients with suspected OLD. Radiologists should familiarize themselves with these imaging features to improve diagnostic accuracy.

• Tuberculosis and Respiratory Diseases
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• v.58 no.2
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• pp.111-119
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• 2005

The introduction of high-resolution CT (HRCT) in recent years has improved the ability of radiologists to detect and characterize the diffuse infiltrative lung disease (DILD). The detection and diagnosis of diffuse lung disease using HRCT are based on the recognition of specific abnormal findings. In this article, pattern recognition of HRCT findings is reviewed in the differential diagnosis of diffuse infiltrative lung disease. In general, HRCT findings of lung disease can be classified into four categories based on their appearances. These categories consist of (1) nodules and nodular opacities, (2) linear and reticular opacities, (3) increased lung opacity, and (4) decreased lung opacity, including cystic lesions.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.17 no.1
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• pp.185-194
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• 1987

The purpose of this study was to aid in diagnosis of salivary gland disease by comparing the sialogram with the scintigram. In this study, 47 patients (52 glands) who had taken the sialography and the scintigraphy were examined. The result of two methods was compared with the clinical and operative diagnosis. The following results are obtained. 1. In inflammatory diseases of the salivary gland, the scintigraphy can be a valuable substitution for a sialography. 2. In inflammatory diseases of the salivary gland, we can get more informations in case of the combined use of the sialography and the scintigraphy. 3. In tumorous lesion of the salivary gland, the sialography is superior to the scintigraphy. But both methods are less valuable in diagnosing the extraglandular tumors.

• Parasites, Hosts and Diseases
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• v.56 no.1
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• pp.71-74
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• 2018

Soluble antigens from an axenic culture of Entamoeba histolytica were used to develop a commercial ELISA kit to quantify anti-E. histolytica antibodies in sera of patients with extraintestinal amebiasis in non-endemic settings. The diagnostic specificity and sensitivity of the test were assessed retrospectively using 131 human serum samples with amoebic serologic status available. They were selected according to their results in immunofluorescence (IFAT) and were separated in 2 sample categories: 64 sera with positive results by IFAT and 67 with negative results by IFAT. The sensitivity and specificity of the ELISA kit were assessed at 95.0% and 94.0% compared to the IFAT. The test can be useful to exclude a potential diagnosis of amebiasis and could be used as a screening method since ELISA is an automated technique.

• Tuberculosis and Respiratory Diseases
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• v.80 no.3
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• pp.241-246
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• 2017

Chronic obstructive pulmonary disease (COPD) is an ambulatory care-sensitive condition, and effective treatment of outpatients can prevent worsening of the illness and hospitalization. Current COPD guidelines provide appropriate guidance for the diagnosis and treatment of patients with COPD. In fact, it has been shown that when appropriate guidance and treatment are performed, the morbidity and mortality rates of COPD patients are reduced. However, there is a gap between the clinical guidelines and the actual clinical treatment. Therefore, the Health Insurance Review and Assessment Service (HIRA) conducted an evaluation of the adequacy of COPD diagnosis and treatment using the Claims Database of HIRA. This review provides a summary of the COPD adequacy assessment results reported by the HIRA and some brief comments on the results.

• Tuberculosis and Respiratory Diseases
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• v.79 no.3
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• pp.127-133
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• 2016

Tuberculosis (TB) is one of the most important occupational risks for healthcare workers (HCWs) in South Korea. Many policies regarding the control and prevention of TB in healthcare settings recommend that HCWs are tested for latent tuberculosis infection (LTBI) in addition to active TB. Moreover, the Korean Tuberculosis Prevention Act also recommends that HCWs receive regular testing for LTBI. However, there are no specific or detailed guidelines for dealing with LTBI in HCWs. Herein, we discuss the diagnosis and treatment of LTBI in HCWs and focus particularly on the baseline screening of hired HCWs, routine follow-up, and contact investigation.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.27 no.2
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• pp.87-90
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• 2016

Cough, the most common symptom, encountered in the outpatient clinic can be caused by various underlying diseases. It defines as chronic cough that the duration of cough is more than 8 weeks with a normal chest X-ray findings. The cause of cough can be found out for more than 90% through the appropriate diagnostic approach and Upper airway cough syndrome, Asthma and Gastroesophageal reflex disease are the most common causes of disease to non-smokers. Chronic cough can be due to not one reason but various reasons and achieve good results by a systematic approach to diagnosis and a concrete treatment on the basis of the sufficient understanding of the underlying disease.

• The Journal of Korean Medicine
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• v.15 no.2 s.28
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• pp.397-411
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• 1994

In the Oriental Medicine, the element of coldness is regarded as one of the important causes which induce female's diseases. Nowadays the number of the female patients is ascending that serously appeal the coldness-sense and pain-sense at the particular part of the body, for example, hand, foot, abdomen, waist, external genital portion and so on. These are caused by female's physiological characteristics of the menstration and delivery, and the influence of the life circumstances, for example, the clothes briefness, the overdiet, oversetting of the airconditioner. The Female's Part-Coldness Syndrome is a disease which the oriental people better than the western people suffer from and if it would be sick for a long time, it could brings into the other diseases. The Oriental Medicine have better effects by the diagnosis and treatment according per symptom in the contrast with the Western Medicine having difficulties in the point of accurate diagnosis and treatment.