• 한국의사학회지
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• 제30권2호
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• pp.45-61
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• 2017

Objectives : This research aims to investigate the consumer's interest in the Korean Medicine (KM) industry by using Google-trends and Naver-Data lab. A quick and uncomplicated way for those who are already involved with KM industry but do not have expertise in utilizing Big-data searches, is introduced. Methods : 'Direct keyword' was set by FGI (Focus Group Interview) and 'Detailed keyword' was set by using relevant word search and autocomplete search functions in the search engine. By inquiring Naver-Data lab, keyword search volumes are compared by age and sex, date range, and originating region of the researcher. It is possible to determine whether the data is reliable or authentic through examining the associated query. Selected direct keywords used through FGI (Focus Group Interview) were 'Acupuncture', 'Herbal Medicine', 'Cupping', 'Musculoskeletal Disease', 'Diet', and 'Stemina'. Based on these keywords, the following results were derived from the keyword analysis. Results : From August 2016, there was a noticeable surge of interest in men's 'Cupping'. The search for 'Diet' increased in the second quarter of 2016 from all ages. The search volume of 'Stemna' for individuals in their 20s is higher than that of those in their 30s or 40s'. Researchers from the region of Chungcheongbuk-do had a higher level of interest in analgesics and less interest in Korean Medicine. There is a greater interest in the KM market from European countries and America, than from Korea, China, and other Asian countries. Discussion : Despite the limitations of the research, it is meaningful to introduce a quick and easy data search method to compare information by age, sex, and region. Conclusion : The future of research into Korea Medicine and this market is confirmed by our data results which indicate interest from Europe, the United States, and other western countries, but less interest from Korea, China and other Asian countries.

• 대한치위생과학회지
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• 제6권2호
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• pp.25-35
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• 2023

연구배경: 전신질환을 보유한 대상자를 위한 임상치과위생사 주도의 치위생관리과정에서의 중요성을 강조하고자 임상적 자료를 근거로 치과 임플란트에 영향을 미치고 있는 전신질환을 파악하고자 하였다. 연구방법: 치과 임플란트에 영향을 미치는 전신질환을 파악하고자 2023년 3월 1일부터 5월 31일까지 문헌고찰을 실시하였으며, 검색 시기는 2000년 1월~2020년 12월까지 국내·외 학술지에 게재된 연구 논문을 대상으로 하였다. 검색에 활용된 국내 database는 학술정보서비스(RISS), 누리미디어(DBpia), 한국학술정보(http://www.papersearch.net;KISS)를 활용하였으며, 국외 database는 Pubmed에서 '치과 임플란트 실패'와 '임플란트와 전신질환' 그리고 Dental implant failures와 Dental implant and systemic disease를 검색하여 전체 383편 중 최종적으로 13편의 자료를 선별하여 분석하였다. 결과: 임플란트의 누적생존률은 평균 94.3%이었으며 실패율은 5.7%이었다. 임상적으로 임플란트와 관련된 전신 질환에 대한 분석결과는 당뇨에 대한 연구가 13편(100.0%)으로 가장 높은 빈도를 차지하였으며 고혈압과 흡연에 대한 연구가 각각 8편(61.5%), 심혈관질환 7편(53.8%), 골관련 질환은 5편(38.5%) 순으로 위험요인이 조사되었다. 그 외 간질환 및 갑상선 이상 그리고 혈액이상 질환과 장기이식 및 감염성 질환 등이 확인되었다. 결론: 임상 치과위생사는 조절되지 않는 전신질환은 임플란트 실패의 위험요인이므로 전신질환이 임플란트에 미치는 영향에 대한 인식과 치위생 사정-판단-수행-평가 등의 주기적인 예방적 치위생관리 과정에서 환자와의 정보공유로 지속적으로 건강한 구강상태를 유지하도록 하여야 할 것이다.

• Molecules and Cells
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• 제43권10호
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• pp.880-888
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• 2020

Inherited peripheral neuropathy is a heterogeneous group of peripheral neurodegenerative disorders including Charcot-Marie-Tooth disease. Many peripheral neuropathies often accompany impaired axonal construction and function. To study the molecular and cellular basis of axon-defective peripheral neuropathy, we explore the possibility of using Caenorhabditis elegans, a powerful nematode model equipped with a variety of genetics and imaging tools. In search of potential candidates of C. elegans peripheral neuropathy models, we monitored the movement and the body posture patterns of 26 C. elegans strains with disruption of genes associated with various peripheral neuropathies and compiled a database of their phenotypes. Our assay showed that movement features of the worms with mutations in HSPB1, MFN2, DYNC1H1, and KIF1B human homologues are significantly different from the control strain, suggesting they are viable candidates for C. elegans peripheral neuropathy models.

• 동의신경정신과학회지
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• 제14권1호
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• pp.175-181
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• 2003

A lot of research have been done so far in terms of traffic accident sequela, but most of them have stressed simply on physical treatments, resulting in less attention to the psychological ones. This is a case report of a patient with post-traumatic stress disorder. Although that is simply following in the wake of past therapy, we were experienced an improved case of post-traumatic stress disorder patient treated by herbal medicine, acupuncture, mental therapeutics. This case effectively describes the characteristics of the post-traumatic stress disorder, and it also suggested one approach for the treatment of the disease. This report is for the better understanding of the disease, and also the search for the advanced treatments to it hereafter.

• Ocean and Polar Research
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• 제39권1호
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• pp.45-49
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• 2017

During the search for anticholinesterase compounds from marine organisms, we were able to isolate 6,6'-bieckol from a red alga, Grateloupia elliptica. This compound showed moderate acetylcholinesterase (AChE) inhibitory activity in a micromole range ($IC_{50}$ $44.5{\mu}M$). However, for butyrylcholinesterase (BuChE), a new target for the treatment of Alzheimer's disease (AD), it showed particularly potent inhibitory activity ($IC_{50}$ $27.4{\mu}M$), which is more potent compared to AChE. It also inhibits BACE-1, a new target for reducing the generation of ${\beta}-amyloid$.

• Journal of Yeungnam Medical Science
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• 제3권1호
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• pp.163-169
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• 1986

Intrapulmonary shunt was measured by $^{99m}Tc$-MAA perfusion tung scan. The study was included 76 patients. Significant amount of intrapulmonary shunt was observed in the pulmonary disease patients and liver disease patients. The shunt amount was correlated well with $PaO_2$ and $AaDO_2$ level. Further study is needed to search the various factors affecting the amount of intrapulmonary shunt.

• Journal of Chest Surgery
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• 제28권4호
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• pp.409-411
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• 1995

One patient developing left main coronary stenosis following double valve replacement is reviewed. Angina pectoris developed 5 months postoperatively. Coronary perfusion with a balloon tip perfusion catheter was performed during previous operation and was considered technically satisfactory. Coronary angiography confirmed stenosis of the left main coronary artery. There was no further coronary arterial disease. An anterior approach between the aorta and pulmonary artery to expose the left main coronary artery was used and patch angioplasty was done. Repeat coronary angiography showed a widely patent left main coronary artery with excellent runoff. A careful search for coronary arterial injury should be made in all symptomatic patients following aortic valve replacement.

• The Korean Journal of Pain
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• 제1권1호
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• pp.3-8
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• 1988

Authors have experienced the treatment for the uppermost frequent cases, herpes zoster, frozen shoulder and low back pain among those who visited our pain clinic. 1. Herpes zoster The Patients who received the treatment within 4 weeks of the onset of the disease, not only healed herpes without leaving post herpetic neuralgia but also crust formation was fast. 2. Frozen shoulder Over 90% of the patients who received suprascapular nerve block accompanied with trigger points electric stimulation was very efficient procedure, futhermore, authors felt keenly the necessity each patients co-operation and individual endurance for this treatment. 3. Low back pain An epidural steroid administration to the patients who did not have any organic disturbances was effective treatment. If this non-effective, search other cause of the disease or operation was advisable one.

• 한국수정란이식학회지
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• 제33권1호
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• pp.49-54
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• 2018

Adenomyosis is a benign gynecological disease frequently affecting women of reproductive age. It has a negative impact on the quality of life, causing bleeding disorders, dysmenorrhea, chronic pelvic pain, and infertility. However, the molecular mechanisms involved in adenomyosis development remain unclear. This paper summarizes the reports found in the MEDLINE database on the molecular mechanisms involved in the development and progression of uterine adenomyosis. The literature search included the following terms: "adenomyosis," "adenomyoma," "pathogenesis," "molecular mechanisms," and "gynecological disorders." Only peer-reviewed, English-language journal articles were included. This review focuses on the molecular genetics, epigenetic modifications, and pivotal signaling pathways associated with adenomyosis development and progression, which will provide insights into and a better understanding of its underlying pathophysiology.

• 한방안이비인후피부과학회지
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• 제16권1호
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• pp.154-158
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• 2003

Objectives : The purpose of this study was to search liquid that mixing with powder drug on acnes disease. Conclusions : Out of acne patients who visited Oriental Medicine Hospital of Han-Seo University during December 2002 - February 2003, four female and five male were treated over four weeks. The average age were 21.44 years old. Before treatment, acne patients were sparsely with papules at the forehead, cheeks, lower jaw. After treatment during four weeks, seven acne patients change for the better, 77.8$\%$(mild improved 55.5$\%$, improved 11.1$\%$, much improved 11.1$\%$)