• Title/Summary/Keyword: Disease condition

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Usefulness of Temporal Subtraction for The Detection of Interval Changes of Interstitial Lung Diseases on Chest Radiographs

  • Higashida, Yoshiharu;Ideguchi, Tadamitsu;Muranaka, Toru;Akazawa, Fumio;Miyajima, Ryuichi;Tabata, Nobuyuki;Ikeda, Hirotaka;Ohki, Masafumi;Toyofuku, Fukai;Doi, Kunio
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.454-456
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    • 2002
  • The evaluation of interval changes between temporally sequential chest radiographs is necessary for the detection of new abnormalities or interval changes, such as pulmonary nodules and interstitial disease. For interstitial lung disease, the interval changes are very important for diagnosis and treatment. Especially, interstitial lung disease may show rapid changes in the radiographs, show changes in the entire lung field in minute detail, or show changes in multiple parts depending on the type. It is therefore difficult to have an accurate grasp of the condition of the disease only with conventional radiographs. The temporal subtraction technique which was developed at the University of Chicago, provides a subtraction image of the current warped image and the previous image. A temporal subtraction image, shows only differences and changes between the two images, can be very useful for a diagnosis of interstitial lung disease. However, the evaluation of the temporal subtraction technique for interstitial lung disease using receiver operating characteristic(ROC) studies has not been reported yet. Therefore, we have evaluated the clinical usefulness of a temporal subtraction technique for detection of interval changes of interstitial lung disease by ROC analysis.

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Meta-analysis Reveals That the Genus Pseudomonas Can Be a Better Choice of Biological Control Agent against Bacterial Wilt Disease Caused by Ralstonia solanacearum

  • Chandrasekaran, Murugesan;Subramanian, Dharaneedharan;Yoon, Ee;Kwon, Taehoon;Chun, Se-Chul
    • The Plant Pathology Journal
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    • v.32 no.3
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    • pp.216-227
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    • 2016
  • Biological control agents (BCAs) from different microbial taxa are increasingly used to control bacterial wilt caused by Ralstonia solanacearum. However, a quantitative research synthesis has not been conducted on the role of BCAs in disease suppression. Therefore, the present study aimed to meta-analyze the impacts of BCAs on both Ralstonia wilt disease suppression and plant (host) growth promotion. The analysis showed that the extent of disease suppression by BCAs varied widely among studies, with effect size (log response ratio) ranging from -2.84 to 2.13. The disease incidence and severity were significantly decreased on average by 53.7% and 49.3%, respectively. BCAs inoculation also significantly increased fresh and dry weight by 34.4% and 36.1%, respectively on average. Also, BCAs inoculation significantly increased plant yield by 66%. Mean effect sizes for genus Pseudomonas sp. as BCAs were higher than for genus Bacillus spp. Among antagonists tested, P. fluorescens, P. putida, B. cereus, B. subtilis and B. amyloliquefaciens were found to be more effective in general for disease reduction. Across studies, highest disease control was found for P. fluorescens, annual plants, co-inoculation with more than one BCA, soil drench and greenhouse condition were found to be essential in understanding plant responses to R. solanacearum. Our results suggest that more efforts should be devoted to harnessing the potential beneficial effects of these antagonists, not just for plant growth promoting traits but also in mode of applications, BCAs formulations and their field studies should be considered in the future for R. solanacearum wilt disease suppression.

A study of subjective periodontal disease of elderly people (노인의 주관적 치주질환에 관한 연구)

  • Jang, Yun-Jung
    • Journal of Korean society of Dental Hygiene
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    • v.9 no.4
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    • pp.836-848
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    • 2009
  • Objectives : This study was conducted to evaluated the subjective oral health state related periodontal disease of elderly people. Methods : Data were collected through the National Health and Nutrition Survey in 2005. Participants consisted of 1,091 elderly people above 65 years old. Independent variables in the survey were social characteristic, health behavior, oral health condition, oral health management. The data were analyzed by using the SPSS 12.0. Results : The more elderly people of 69.0% recognized own oral health as is not healthy, elderly people of 74.0% recognized own oral health as is not healthy about subjective oral health and a lot of stressed(82.8%) has felt highly about periodontal disease(p<0.001). Respondents of have a sound teeth(58.9%), have a lower denture(75.0%) and have a no problem in mastication(74.5%) has felt highly about periodontal disease(p<0.001). Elderly people recognized own oral health as is not healthy about subjective oral health were 0.316 times(p<0.01), elderly people recognized own oral health as is common healthy about subjective oral health were 0.241 times(p<0.001), a lot of stressed were 1.410 times has felt highly about periodontal disease. Elderly people of have a lower denture were 1.159 times, have a upper denture were 1.159 times, have a lower and upper denture were 0.464 times has felt highly about periodontal disease(p<0.05). Also respondents of have a no problem in mastication were 7.464 times compared with problem in mastication(p<0.001). Conclusions : Quality of life from disease of Korean elderly people can be fallen, and improve quality of life that medical treatment is healthy numerical value state numerical value state. Study's findings of above may be used to inform the importance of health numerical value state while establish dental health policy that is string.

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Clinical Experiences of Open Heart Surgery - A Report of 126 Case - (개심술 126례의 임상적 고찰)

  • 이종국
    • Journal of Chest Surgery
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    • v.22 no.6
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    • pp.1025-1035
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    • 1989
  • Since we first performed open heart surgery on December 30, 1986, 126 cases were operated on up to August 31, 1989. Among the 126 cases, 65 cases were congenital heart disease of which 63 were acyanotic disease, and 61 cases were acquired heart disease, most of which were valvular heart disease. The age distribution of congenital heart disease was from 1 years 2 months to 48 years, and males had a slightly higher incidence. The age of acquired heart disease was from a minimum of 15 years to a maximum of 68 years, and the male to female ratio was 1;1.5. Midsternotomy was performed in all cases, and the aortic cannula was inserted through ascending aorta and the venous cannula inserted into the SVC and IVC through the right atrium. Vent was inserted through the right superior pulmonary vein. Cardioplegia solution was used in all cases; it was composed of sodium bicarbonate 3.5 ampule, KCL 14 mEq, 2% lidocaine 2.5 ml, 20 % albumin 50 ml and heparin 1000 units mixed to 950 ml with Hartman solution, and was made to 4oC and infused 10 ml per Kg every 20 minutes. The congenital heart disease had a variety of VSD in 32 cases, ASD 23 cases, PS 6 cases, PDA 2 cases, and one case each of Ebsteins anomaly and tricuspid atresia. The operations performed for acquired heart disease were 4 cases of OMC, 33 cases of MVR, and 5 cases of AVR, and 1 case of AVR with CABG. DVR was perfomed in 13 cases, and triple valve replacement was done in 1 case. Other than these, excision of LA myxoma was 2 cases, and repair of traumatic VSD and removal of a pulmonary embolism were one case each. The surgical mortality was 5 cases[4%], all of which occurred in valve replacement cases. Follow-up study revealed 2 late deaths. One died after a traffic accident and one died due to sepsis after he had received a gastrectomy for ulcer bleeding. The remaining patients were in good condition.

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The clinical observations of 4 case of De Quervain's Disease treated with Cervus elaphus Herbal-acupuncture (녹용약침으로 치료한 De Quervain's Disease 4례 증례보고)

  • Park, Jun-sung;Kim, Woo-young;Paek, Seung-tae;Lee, Seung-deok;Kim, Kap-sung
    • Journal of Acupuncture Research
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    • v.21 no.6
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    • pp.259-267
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    • 2004
  • De Quervain's disease is caused by stenosing tenosynovitis of the first dorsal compartment of the wrist. The first dorsal compartment at the wrist includes the tendons of the abductor pollicis longus (APL) and the extensor pollicis brevis (EPB). Patients with De Quervain's usually report pain at the dorsolateral aspect of the wrist with referral of pain toward the thumb and/or lateral forearm. This condition responds well to nonsurgical treatment. Objective : The aim of this study was to find out the therapeutic effect of the Cervus elaphus Herbal-acupuncture in the treatment of patients with De Quervain's Disease. Design : A prospective study of Cervus elaphus Herbal-acupuncture was conducted. Setting : The study was conducted in the Kang-nam Oriental Hosp. of Dong-Guk University. Patients : The study comprised 4 patients with De Quervain's Disease. Methods : We investigated 4 cases patients the De Quervain's Disease. We evaluated wrist function that before and after Cervus elaphus Herbal-acupuncture treatment by VAS score, tenderness and Finkelstein test. the treatment is operated every other day. Results : Pain reduction(VAS) was found out in the case treated with Cervus elaphus Herbal-acupuncture. Conclusions : Clinical results show that Cervus elaphus Herbal-acupuncture has a good analgesic effect in De Quervain's Disease.

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The effects of mental health status and subjective oral health status on periodontal disease for the elderly (노인의 정신건강과 주관적 구강건강상태가 치주질환에 미치는 영향)

  • Kim, Ye-Hwang;Lee, Jung-Hwa
    • Journal of Korean society of Dental Hygiene
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    • v.19 no.4
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    • pp.555-564
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    • 2019
  • Objectives: The purpose of this study was to investigate how mental health status affects oral health in the elderly. Methods: The subjects of the study provided the data for the sixth Korea National Health and Nutrition Examination Survey from 2013 to 2015. Four-hundred and twenty-one subjects were selected for the study. All data were analyzed by complex sampling frequency, chi-square test, and composite multiple regression analysis using SPSS 21.0 version. In addition, a significance level of 0.05 was considered. Results: The general factors affecting cases of periodontal disease were general characteristics, mental health status, oral health status, elderly males, household income, education level, daily brushing frequency, speaking, and stress. The effect of periodontal disease was 1.64 times higher in the male group than in the female group (p<0.001). In the household income level, the 'low' group had 1.91 times more periodontal disease, while the 'mid low' group had 1.64 times more periodontal disease than the 'high' group (p<0.05). Periodontal disease was found to be lower in the group that recognized subjective oral health status as 'good' (p<0.05). The study subjects had low levels of periodontal disease when there was no speaking difficulty (p<0.05). Conclusions: Therefore, in order to improve oral health of the elderly, it is necessary to understand the mental health condition of the elderly and prepare proper oral health education programs accordingly. Institutional devices for various oral health projects should be prepared, as well.

A Case of IgG4-Related Pseudotumor in Larynx (후두에서 기원한 IgG4 연관 가성 종양 1예)

  • Lee, Min Hyuk;Hong, Joon Pyo;Kim, Tae Hwan;Jin, Sung Min
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.33 no.2
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    • pp.110-114
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    • 2022
  • IgG4-related disease is a fibroinflammatory condition by infiltration of IgG4-positive plasma cells that often presents as a tumorous lesion. This disease can affect nearly every organ system. After the pancreas, the head and neck region is second most common site for presentation of IgG4-related disease such as Mikulicz's disease, Küttner tumor. The involvement of IgG4-related disease in laryngeal lesions is extremely rare. We have experienced a case of IgG4-related disease with pseudotumor formation in the larynx that is suggestive of malignancy in radiologic findings. But the pathology findings was finally confirmed as IgG4-related disease. Oral treatment with prednisolone was initiated, and the edematous mass reduced in size without permanent functional impairment of vocal fold mobility. We report our experience with a literature review.

A Study on the Ohguktong(吳鞠通)'s Upper Burner[上焦] in "The Sections of Warm Disease(溫病條辨)" (오국통(吳鞠通)의 "온병조변(溫病條辨)"중(中) 상초(上焦)에 관한 연구(硏究))

  • Kim, Young-Doo;Shin, Seung-Yuel;Cho, Kyung-Jong;Lee, Seok-Jae;Keum, Kyung-Soo;Lee, Si-Hyeong
    • Journal of Korean Medical classics
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    • v.21 no.3
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    • pp.177-258
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    • 2008
  • An Epidemic disease is regarded as warm disease by Korean Medicine. Warm disease is highly contagious and shows an unfavorable condition, and that is characteristic of being widely prevalent. Warm disease study cope with this epidemic disease opportunely. In the Myeong[明] and Cheong[淸] Dynasty, warm disease study got into the region of Korean medicine of today and "The Sections of Warm Disease(溫病條辨)" contributed to the cause of the study was really great. "The Sections of Warm Disease" written by Ohguktong(吳鞠通) in the Cheong Dynasty are divided into the three sections of Upper burner[上焦], Middle burner[中焦] and Lower burner[下焦]. Ohguktong, dealing with the contents of Defense-aspect[衛分], Gi-aspect[氣分], Construction-aspect[營分], Blood-aspect[血分], and so forth in all "Sections of Warm Disease", made use of Seopcheonsa(葉天士)'s Defense Gi[衛氣], Construction, and Blood pattern identification with Triple burner[三焦] pattern identification and six channel pattern identification. And he, having a correct understanding of the nature of medicine, suggested in detail that the directions of medicine and described the processing according to method and the method to take medicine. To conclude, Ohguktong(吳鞠通) Tong in "The Sections of Warm Disease" not only formulated the system of the practical theory of warm disease but also solidified the foundation covering warm disease and its treatment as well, He established the new method of treatment and formula related to warm disease and made a definite distinction between cold damage[傷寒] and warm disease[溫病].

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Taxonomy of fungal complex causing red-skin root of Panax ginseng in China

  • Lu, Xiao H.;Zhang, Xi M.;Jiao, Xiao L.;Hao, Jianjun J.;Zhang, Xue S.;Luo, Yi;Gao, Wei W.
    • Journal of Ginseng Research
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    • v.44 no.3
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    • pp.506-518
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    • 2020
  • Background: Red-skin root of Asian ginseng (Panax ginseng) significantly reduces the quality and limits the production of ginseng in China. The disease has long been thought to be a noninfectious physiological disease, except one report that proved it was an infectious disease. However, the causal agents have not been successfully determined. In the present study, we were to reveal the pathogens that cause red-skin disease. Methods: Ginseng roots with red-skin root symptoms were collected from commercial fields in Northeast China. Fungi were isolated from the lesion and identified based on morphological characters along with multilocus sequence analyses on internal transcription spacer, β-tubulin (tub2), histone H3 (his3), and translation elongation factor 1α (tef-1α). Pathogens were confirmed by inoculating the isolates in ginseng roots. Results: A total of 230 isolates were obtained from 209 disease samples. These isolates were classified into 12 species, including Dactylonectria sp., D. hordeicola, Fusarium acuminatum, F. avenaceum, F. solani, F. torulosum, Ilyonectria mors-panacis, I. robusta, Rhexocercosporidium panacis, and three novel species I. changbaiensis, I. communis, and I. qitaiheensis. Among them, I. communis, I. robusta, and F. solani had the highest isolation frequencies, being 36.1%, 20.9%, and 23.9%, respectively. All these species isolated were pathogenic to ginseng roots and caused red-skin root disease under appropriate condition. Conclusion: Fungal complex is the causal agent of red-skin root in P. ginseng.