• Title/Summary/Keyword: Discharge change

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Traditional Korean Medicine for Non-Small Cell Lung Cancer Patient Undergoing Pembrolizumab Immunotherapy: A Case Report (Pembrolizumab 면역치료를 시행 중인 비소세포성 폐암환자의 한방치료 증례보고)

  • Shim, So-hyun;Seo, Hee-jeong;Seo, Hyung-bum;Cho, Im-hak;Lee, Chan;Kim, So-yeon;Han, Chang-woo;Park, Seong-ha;Yun, Young-ju;Lee, In;Kwon, Jung-nam;Hong, Jin-woo;Choi, Jun-yong
    • The Journal of Internal Korean Medicine
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    • v.40 no.4
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    • pp.709-722
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    • 2019
  • Objective: The purpose of this study was to report the effect of traditional Korean medicine (TKM) in alleviating the side effects of lung cancer patient undergoing immunotherapy. Method: A 43-year-old man, who was diagnosed with non-small cell lung cancer, received pembrolizumab treatments. The patient was treated with acupuncture and herbal medicine (Geoeoyangpye-tang) to control various uncomfortable symptoms. The degree of pain was measured by the numeric rating scale (NRS). The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, Core 30 (EORTC QLQ-C30) and the EORTC 13-item lung cancer-specific module (EORTC LC-13 questionnaire) were used to assess the change in the quality of life. Results: After the TKM treatment, the flank pain and arthralgia based on the NRS were significantly improved. Various uncomfortable symptoms such as fatigue, dyspnea, insomnia, and loss of appetite were also significantly improved, based on the EORTC QLQ-C30 and EORTC QLQ-LC13. The size of the primary tumor was decreased during treatment. The disease status was stable radiologically after two months from discharge.

Superelevation and Bed Variation Due to Attack Angle of Submerged Vanes in Curved Channel (수제 입사각에 따른 개수로 만곡부의 편수위와 하상변동)

  • Park, Sang Deog;Paik, Joongcheol;Jeon, Woo Sung;Lee, Hyun Jae
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.39 no.2
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    • pp.297-306
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    • 2019
  • Since the centrifugal force acts on the flow in the curved channel, a transverse water surface gradient occurs and the thalweg is biased toward the outer bank. The submerged vanes may be used to solve various engineering problems of the curved channels. In order to analyze the influence of an attack angle and the distance between the vane arrays on the river bed variation and the superelevation in a bend, movable bed hydraulic experiments were conducted in a $90^{\circ}$ curved rectangular channel of a small-size gravel bed. Installing the submerged vanes in the bend increases the maximum scour depth. But if vanes are installed in a uniform obtuse angle, the scour depth may be reduced. If the flow rate in the channel bend with vanes equals to the channel forming discharge, the location of the maximum scour depth moved to the downstream and the superelevation increased. However if the flow rate is smaller than that, the location of the maximum scour depth moved upstream and the superelevation decreased. The channel bed change and the superelevation due to the installation of the submerged vanes have been dependent on the interaction of the attack angle, the flow rate, and the distance between the arrays.

Verification of effectiveness of evaluation of long-term care institution (장기요양기관(시설급여) 평가의 효과성 검증)

  • Kim, Yun-Jeong;Kim, Young-Jea;Lee, Sang-Jin
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.9 no.5
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    • pp.781-791
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    • 2019
  • The purpose of this study was to evaluate the evaluation of long - term care institutions (evaluation rating, evaluation rating, suitability of evaluation index), quality of service of caregivers, Quality satisfaction, life satisfaction, and facility choice. After receiving the IRB, in January and February of 2018, the survey was completed for 79 long-term care institution managers, 381 nursing care workers, and 381 elderly people. The survey carried out an allocation sample reflecting the 2015 long - term care (facility benefit) evaluation results. The results of this study are as follows. First, it is found that the institutional evaluation (evaluation level, change of evaluation level, recognition of suitability of the index) has a greater impact on the quality of life of the elderly, appear. However, the intention of reselecting the facility after discharge was more influenced by the quality of services of caregivers. Therefore, except for the intention to reschedule the facility, it can be said that the evaluation of the National Health Insurance Corporation was partially validated.

Analysis of Applicability of the Detention in Trunk Sewer for Reducing Urban Inundation (도시 내수침수 저감을 위한 간선저류지 적용성 분석)

  • Lee, Sung Ho;Kim, Jung Soo;Kim, Seo Jun
    • Ecology and Resilient Infrastructure
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    • v.8 no.1
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    • pp.44-53
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    • 2021
  • The flood prevention capacity of drainage facilities in urban areas has weakened because of the increase in impervious surface areas downtown owing to rapid urbanization as well as localized heavy rains caused by climate change. Detention can be installed in trunk sewers and linked to existing drainage facilities for the efficient drainage of runoff in various urban areas with increasing stormwater discharge and changing runoff patterns. In this study, the concept of detention in trunk sewers, which are storage facilities linked to existing sewer pipes, was applied. By selecting a virtual watershed with a different watershed shape, the relationship between the characteristic factors of detention in the trunk sewer and the design parameters was analyzed. The effect of reducing stormwater runoff according to the installation location and capacity of the reservoir was examined. The relationship between the installation location and the capacity of the detention trunk sewer in the Dowon district of the city of Yeosu, South Korea was verified. The effects of the existing water runoff reduction facility and the detention trunk sewer were also compared and analyzed. As a result of analyzing the effects of reducing internal inundation, it was found that the inundation area decreased by approximately 66.5% depending on the installation location of the detention trunk sewer. The detention trunk sewer proposed in this paper could effectively reduce internal inundation in urban areas.

Profile and Outcome of Management of Brain Tumours in Kaduna Northwestern Nigeria

  • Danjuma, Sale;Dauda, Happy Amos;Kene, Aghadi Ifeanyi;Akau, Kache Stephen;Jinjiri, Ismail Nasiru
    • Journal of Korean Neurosurgical Society
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    • v.65 no.5
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    • pp.751-757
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    • 2022
  • Objective : Tumours of the brain are a rare occurrence accounting for approximately 2% of all neoplasms in adults. Few studies have been done in Nigeria on the profile of brain tumours. The aim of this study is to determine the profile of brain tumours in general and determine the change in Kanofsky Performance Score (KPS) after treatment. Methods : This is a prospective hospital-based study in Kaduna. All consecutive patients over 18 years of age with diagnosis of brain tumours from January 2016 to December 2019 were included in the study. Demographic and clinical data was collected using a proforma during the study. Patients who received treatment were followed up for 12 months. The primary outcome data was the difference in the quality of life as measured by KPS at the point of first contact and at 1-month after treatment and at 12-month follow up. Data obtained was analysed with SPSS version 25.0 for Windows. Descriptive statistics was done to determine the profile. Paired t-test at 95% confidence interval was done to check for significant correlation between the mean KPS. Results : A total of 39 consecutive patients were included in the study. There was a slight male preponderance with a M : F of 1.17 : 1. Meningioma and metastasis were more common in females while gliomas and pituitary tumours were more common in males. The mean age of patients was 49.8 years and standard deviation of 11.8 years. Pituitary tumours were the most common tumours. The most common location of the tumour was frontal lobe followed by the pituitary gland. The mean duration of symptoms before neurosurgical consultation was 38 weeks. The most common presenting symptoms of patient with brain tumour was headache. The quality of life improve compare to the baseline in 81% of patient at discharge and at 1 year follow up. The overall mortality rate was 25.6%. Conclusion : The most common brain tumour in our study is pituitary tumour. Most patients present late. The most common presenting symptoms is headache. There is significant improvement in the KPS of patients following treatment. The overall mortality rate at 1-year post treatment is 25.6%.

Effects of Korean Medicine on 20 Post-TKR Inpatients: A Retrospective Observational Study (슬관절 전치환술 후 한방병원에 입원한 환자 20명에 대한 후향적 분석)

  • Im, Ji-Sung;Kim, Ji-Eun;Jeong, Yeong-jin;Kang, Do-Young;Park, Eun-Sang;Kim, Jong-gyu;Song, Yung-sun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.36 no.4
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    • pp.138-142
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    • 2022
  • This study aimed to evaluate the effectiveness of Korean rehabilitation treatement for patients with post-TKR. The medical records of inpatients undergoing Korean rehabilitation treatment after TKR from 2016.01.01. to 2021.12.31. during the admission, were analyzed retrospectively. The effect of treatment was evaluated by using a numeric rating scale(NRS) and range of motion(ROM) of knee. Statistical analysis was done using the IBM SPSS statistics 26 program. If the period of hospitalization was within 7 days or change of NRS and ROM was not recorded properly, the case was excluded. All inpatients received acupuncture treatment, Electro-acupuncture. Soyeom pharmaco-acupuncture were used at a high rate. Blood letting cupping therapy, dry cupping therapy, Interferential Current Therapy(ICT) continuous passive motion(CPM), cryotherapy were used at a high rate. A significant improvement was noted when comparing the NRS and knee ROM results at the time of admission and discharge. Korean medical rehabilitation can be effectively used for patients who have undergone TKR, to relieve pain and enable returning to daily activities. It is expected to be helpful in future studies of post-TKR in Korean Medicine. Also It can be used for medical treatment of post-TKR in Korean Medicine Hospital and clinic. However, further research with a high level of evidence is necessary to support this finding.

A study on the development of a Blue-green algae cell count estimation formula in Nakdong River downstream using hyperspectral sensors (초분광센서를 활용한 낙동강 하류부 남조류세포수 추정식 개발에 관한 연구)

  • Kim, Gwang Soo;Choi, Jae Yun;Nam, Su Han;Kim, Young Dod;Kwon, Jae Hyun
    • Journal of Korea Water Resources Association
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    • v.56 no.6
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    • pp.373-380
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    • 2023
  • Due to abnormal climate phenomena and climate change in Korea, overgrowth of algae in rivers and reservoirs occurs frequently. Algae in rivers are classified into green algae, blue-green algae, diatom, and other types, and some species of blue-green algae cause problems due to odor and the discharge of toxic substances. In Korea, an algae alert system is in place, and it is issued based on the number of harmful blue-green algae cells. Thus, measuring harmful blue-green algal blooms is very important, and currently, the analysis method of algae involves taking field samples and determining the cell count of green algae, blue-green algae, and diatoms through algal microscopy, which takes a lot of time. Recently, the analysis of algae concentration through Phycocyanin, an alternative indicator for the number of harmful algae cells, has been conducted through remote sensing. However, research on the analysis of the number of blue-green algae cells is currently insufficient. In this study, we water samples for algal analyses were collected from river and counted the number of blue-green algae cells using algae microscopy. We also obtained the Phycocyanin concentration using an optical sensor and acquired algae spectra through a hyperspectral sensor. Based on this, we calculated the equation for estimating blue-green algae cell counts and estimated the number of blue-green algae cells.

Determination of Floodplain Restoration Area Based on Old Maps and Analysis on Flood Storage Effects of Flood Mitigation Sections (고지도를 활용한 홍수터 복원 구역 선정 및 홍수완충공간의 홍수 저류효과 분석)

  • Dong-jin Lee;Un Ji;Sanghyuk Kim;Hong-Kyu Ahn;Eun-kyung Jang
    • Ecology and Resilient Infrastructure
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    • v.10 no.2
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    • pp.40-49
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    • 2023
  • To reduce the damage of extreme flooding caused by climate change and to create flood mitigation sections in a nature-friendly riparian area, it is necessary to restore the floodplain area by referring to the past floodplain section of the current inland waterfront area before the levee was built. This study proposed a method of selecting a location for floodplain restoration using old maps of the Geum River study section and analyzed the effect of flood level reduction through unsteady flow numerical simulations using the floodplain as a flood mitigation space. As a result of analyzing changes in the river areas using old maps, the river section was estimated to gradually reduce by 27.8% (1,059,380 m2) in 2020 compared to 1919, and it was found to have an effective storage capacity of 2,200,868 m3 when restored to offline storage. The flood level and discharge control effects analyzed based on HEC-RAS unsteady flow simulation were 16 cm and 219.01 m3/s, respectively, in the downstream cross-section. In the numerical simulation in this paper, the flood mitigation space was applied as an offline reservoir. The effect of reducing the flood level may differ if levee retreat/relocation is applied.

Performance and Characterization of Ceramic Membrane by Phase Inversion-Extrusion Process with Polymer Binder Mixing (상전이-압출 알루미나 분리막 제조 공정에서 혼합 고분자 바인더 적용에 따른 성능 및 특성 평가)

  • Sojin Min;Ahrumi Park;Yongsung Kwon;Daehun Kim;You-In Park;Seong-Joong Kim;Seung-Eun Nam
    • Membrane Journal
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    • v.33 no.6
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    • pp.439-446
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    • 2023
  • Ceramic membranes are generally used for various industrial processes operating under extreme conditions because of its high thermal and chemical stability. However, due to the trade-off phenomenon of permeability and mechanical strength, preparation of high permeability-high strength membrane is necessary. In this study, the change in characteristics and performances of ceramic membranes was analyzed depending on the type of polymer binder and its mixing ratio. Because the solubility between solvent and polymer binder was higher in PSf (polysulfone) than in PES (polyethersulfone), the viscosity and discharge pressure of the PSf-based dope solution were higher than those of PES-based dope solution. When PSf was used as a polymer binder, ceramic membrane showed high mechanical strength and low water permeability due to the dense structure. On the other hand, in case of PES, the mechanical strength was slightly reduced and the water permeability was increased. It was confirmed that the optimum mixing ratio of the PSf and PES with high water permeability and mechanical strength was 9:1.

Assessing the Applicability of Hysteresis Indices for the Interpretation of Suspended Sediment Dynamics in a Forested Catchment (산림유역의 부유토사 동태 해석을 위한 이력현상 지수의 적용성 평가)

  • Ki-Dae Kim;Su-Jin Jang;Soo-Youn Nam;Jae-Uk Lee;Suk-Woo Kim
    • Korean Journal of Environment and Ecology
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    • v.38 no.2
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    • pp.178-188
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    • 2024
  • The dynamics of suspended sediment (SS) in forested catchments vary depending upon human or natural disturbances, including land use change, forestry activity, forest fires, and landslides. Understanding the dynamics of SS originating from the potential sources within a forested catchment is crucial for establishing an effective water quality management strategy. Therefore, to suggest a systematic method for interpreting SS dynamics, we evaluated the performance and applicability of ten methods for calculating the hysteresis index based on observed hydrological data and two calculation models (Lawler's method and Lloyd's method) with five sampling intervals (50th, 25th, 10th, 5th, and 1st percentiles). Our results showed that Lloyd's method, which used a sampling interval at the 1st percentile, had the largest number of analyzable runoff events and exhibited the best performance. The results of this study can contribute to quantifying the hysteresis in the relationship between discharge and SS and provide useful information for interpreting SS dynamics.