• Journal of Nutrition and Health
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• 제36권5호
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• pp.515-527
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• 2003

Objectives： A meta-analysis of the literatures was conducted to evaluate the cost-effectiveness of medical nutrition therapy by dietitians. Methods : The 30 studies were identified from a computerized search of published research on MEDLINE, Science-Direct and the PQD database until May, 2002 and a review of reference lists. The main search terms were“dietitian”,“dietary intervention”,“nutrition intervention”, “cost”,“cost-effectiveness”and“cost-benefit analysis”. The subgroup analysis was performed by publication year, study design, intervention provider, type of patient (in/out-patient) and type of cost (total cost/direct cost). Two reviewers independently selected trials for inclusion, assessed the quality and extracted the data. Results : The 30 studies were identified using the electric database search and bibliographies. The 17 trials were eligible for inclusion criteria, then the systematic review and a meta-analysis were conducted on effectiveness and cost-effectiveness of medical nutrition therapy. The quality of the studies was evaluated using the quality assessment tool for observational studies. The quality score was 0.515 $\pm$ 0.121 (range : 0.279-0.711, median : 0.466). The meta-analysis of 17 studies based on the random effect model showed that medical nutrition therapy was highly effective in treating the diseases (effect size 0.3092 : 95% confidence interval 0.2282-0.3303). The vote-counting method, one of meta-analysis methods, was applied to evaluate the cost-effectiveness of medical nutrition therapy conducted by dietitians. Two criteria (method 1, method 2) for voting were used. The calculated p-values for method 1 (more conservative method) and method 2 (less conservative method) were 0.1250 and 0.0106, respectively. Medical nutrition therapy by dietitians was significantly cost-effective in the method 2. Conclusion. This meta-analysis showed that the effectiveness of medical nutrition therapy was statistically significant in treating disease (effect size 0.3092), and that the cost-effectiveness of medical nutrition therapy was statistically significant in the method 2 (less conservative method) of vote counting. (Korean J Nutrition 36(5): 515~527, 2003)

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2006년도 춘계학술대회논문집
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• pp.894-901
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• 2006

In general, the tension fores of hanger cable in suspension bridges play an important role in evaluating the bridge state. The vibration method, as a conventional one, has been widely applied to estimate the tension fores by using the measured frequencies on hanger cables. However, the vibration method is not applicable to short hanger cables because the frequency of short cables is severely sensitive to the flexural rigidity. Thus, in this study, the tension forces of short hanger cables, of which the length is shorter than 10meters, were estimated through back analysis of the cable frequencies measured from Gwang-An suspension bridge in Korea. Direct approach to rock analysis is adopted using the univariate method among the direct search methods as an optimization technique. The univariate method is able to search the optimal tension forces without regard to the initial ones and has a rapid convergence rate. To verify the feasibility of back analysis, the results from back analysis and vibration method are compared with the design tension forces. From the comparison, it can be inferred that back analysis results are more reasonable agreement with the design tension forces of short hanger cable. Therefore, it is concluded that back analysis applied in this study is an appropriate tool for estimating tension forces of short hanger cables.

• 대한토목학회논문집
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• 제32권6A호
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• pp.369-378
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• 2012

이 연구에서는 풍력 터빈 블레이드의 형상 최적화를 위한 직접탐색 기반의 최적화 기법을 적용하고, 최적화 기법간의 성능을 비교하여 효과적인 방법을 제안하고자 하였다. 이를 위하여 수평축 풍력 터빈의 최적설계 코드인 HARP_Opt(Horizontal Axis Rotor Performance Optimizer)을 기반으로 연간 발전량 평가 방법을 수정하고, HARP_Opt에서 적용하고 있는 기존의 유전자 알고리즘과 함께 패턴 서치 방법을 추가 적용하였다. 이를 1MW급 풍력 발전 터빈 블레이드의 단면 형상 최적 설계 문제에 적용하였으며, 기존의 유전자 알고리즘 및 마이크로 유전자 알고리즘, 그리고 패턴 서치 방법의 성능을 비교한 결과, 연간 발전량과 해의 일관성 면에 있어서는 패턴 서치 방법이 상대적으로 우수하였으며, 계산시간 측면에서는 마이크로 유전자 알고리즘이 상대적으로 우수한 것으로 분석되었다.

• 한국자동차공학회논문집
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• 제6권4호
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• pp.76-85
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• 1998

Recently, Genetic Algorithm(GA) is widely adopted into a search procedure for structural optimization, which is a stochastic direct search strategy that mimics the process of genetic evolution. This methods consist of three genetics operations maned selection, crossover and mutation. Contrast to traditional optimal design techniques which use design sensitivity analysis results, GA, being zero-order method, is very simple. So, they can be easily applicable to wide area of design optimization problems. Also, owing to multi-point search procedure, they have higher probability of converge to global optimum compared to traditional techniques which take one-point search method. In this study, a method of finding the optimum values of suspension parameters is proposed by using the GA. And vehicle is modelled as planar vehicle having 5 degree-of-freedom. The generalized coordinates are vertical motion of passenger seat, sprung mass and front and rear unsprung mass and rotate(pitch) motion of sprung mass. For rapid converge and precluding local optimum, share function which distribute chromosomes over design bound is introduced. Elitist survival model, remainder stochastic sampling without replacement method, multi-point crossover method are adopted. In the sight of the improvement of ride comfort, good result can be obtained in 5-D.O.F. vehicle model by using GA.

• 생물정신의학
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• 제25권4호
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• pp.89-100
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• 2018

Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation method that delivers 1-2 mA of current to the scalp. Several clinical studies have been conducted to confirm the therapeutic effect of major depressive disorder (MDD) patients with tDCS. Some studies have shown tDCS's antidepressant effect, while the others showed conflicting results in antidepressant effects. Our aim of this review is to understand the biological bases of tDCS's antidepressant effect and review the results of studies on tDCS's antidepressant effect. For the review and search process of MDD treatment using tDCS, the US National Library of Medicine search engine PubMed was used. In this review, we discuss the biological mechanism of tDCS's antidepressant effect and the existing published literature including meta-analysis, systematic review, control trial, open studies, and case reports of antidepressant effects and cognitive function improvement in patients with MDD are reviewed. We also discuss the appropriate tDCS protocol for MDD patients, factors predictive of response to tDCS treatment, the disadvantages of tDCS in MDD treatment, and side effects.

• 반도체디스플레이기술학회지
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• 제16권3호
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• pp.106-110
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• 2017

Due to the plasma applied from the outside, which acts as an etchant during the etching process, considerable heat is transferred to the wafer and a separate cooling process is performed to effectively remove the heat after the process. In this case, a direct cooling method using a refrigerant is suitable for cooling through effective heat exchange. The direct cooling method using the refrigerant using the latent heat exchange is superior to the cooling method using the sensible heat exchange. Therefore, in this paper, AMESim is used to design a direct refrigerant cooling system using latent heat exchange simulator was built.The constructed simulator is reliable compared with the actual experimental results. It is expected that this simulator will help to design and search for optimal process conditions.

• 터널과지하공간
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• 제4권1호
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• pp.17-23
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• 1994

This study consists of two procedures on back analysis and forward analysis which is a basic tool of the former. For a safe and economical construction of underground structures, it is required to identify the structural parameters and analyze the structural behavior as exactly as possible. In this paper, a boundary element method to analyze the behavior of multi-alyered underground structures is studied, in which body forces and initial stresses are considered. That is, each layer is discritized into subregions using infinite fundamental solutions, and terms of body forces and initial stresses are transformed into boundary integral where the applied direct integral method is used. And the system of equations containing body forces and initial stresses are considered. That is, each layer is discritized into subregions using infinite fundamental solutions, and terms of body forces and initial stresses are transformed into boundary integral where the applied direct integral method is used. And the system of equations containing body forces and initial stresses are composed, then the method to solve unknowns is used with applying compatibility and equilibrium conditions between interfaces. As well, the direct search method is applied in back analysis problems. By Powell's method as a technique to search unknown parameters, assuming displacements calculated from boundary element analysis as in-situ displacements, elastic moduli and initial stresses are presumed. As consequences of this study, the results of boundary element analysis of the behavior of multilayered structure considering body forces and initial stresses are agreed with those of finite element analysis. And results of back analysis of elastic moduli and initial stresses in each layers are agreed with exact values with a little difference. Therefore, it is known that this study can be efficiently applied for analyzing the behavior of underground structures including back analysis problems.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2009년도 춘계학술대회 논문집 전기설비전문위원
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• pp.74-76
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• 2009

In this paper, search method and sliding mode observer are developed for efficiency optimization of induction motor. The proposed control scheme consists of efficiency controller and adaptive backstepping controller. A search controller for which information of input of fuzzy controller is included in efficiency controller that uses a direct vector controlled induction motor. The search controller is based on the "Rosenbrock" method and finds the flux level at the minimum input power of induction motor. Once this optimal flux level has been determined, this information is utilized to update the rule base of a fuzzy controller A sliding mode observer is designed to estimate rotor flux and an adaptive backstepping controller is also used to compensate for mechanical uncertainties in the speed control of induction motor. Simulation results are presented to validate the proposed controller.

• 한국강구조학회 논문집
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• 제14권2호
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• pp.339-348
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• 2002

본 논문에서는 비선형 해석을 이용한 강뼈대 구조물의 자동화설계를 수행한다. 기하학적 비선형은 안정함수를 사용하여 고려한다. 보-기둥 부재에 대하여 전단변형 효과를 고려한다. 자동화 설계 기법으로는 직접 탐색법을 사용한다. LRFD의 상관방정식으로 각각의 부재의 상관 계수 값을 계산하여 가장 큰 상관 계수 값을 가지는 부재의 크기를 데이터베이스에서 단계별로 증가시킨다. 목적함수는 강뼈대 구조물의 중량을 사용하며, 계약조건식은 하중-저항능력, 처짐, 층간 수평변위 및 연성도를 고려한다. 2차원과 3차원 2층 강뼈대구조물에 대한 예제 해석을 수행한다.

• 한국정밀공학회지
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• 제14권12호
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• pp.24-29
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• 1997

Recently, Genetic Algorithm(GA), which is a stochastic direct search strategy that mimics the process of genetic evolution, is widely adapted into a search procedure for structural optimization. Contrast to traditional optimal design techniques which use design sensitivity analysis results, GA is very simple in their algorithms and there is no need of continuity of functions(or functionals) any more in GA. So, they can be easily applicable to wide area of design optimization problems. Also, owing to multi-point search procedure, they have higher porbability of convergence to global optimum compared to traditional techniques which take one-point search method. The methods consist of three genetics opera- tions named selection, crossover and mutation. In this study, a method of finding the omtimum size and topology of drilling machine is proposed by using the GA, For rapid converge to optimum, elitist survival model,roulette wheel selection with limited candidates, and multi-point shuffle cross-over method are adapted. And pseudo object function, which is the combined form of object function and penalty function, is used to include constraints into fitness function. GA shows good results of weight reducing effect and convergency in optimal design of drilling machine.