• 한국항해항만학회지
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• 제27권4호
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• pp.443-447
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• 2003

본 논문에서는 $0.2\mu\textrm{m}$ GaAs MODFET(modulation doped FET)를 이용하여 제작한 위성방송수신용 고성능 다운컨버터 MMIC에 관해서 보고한다. GaAs 화합물 반도체 기판상에 제작된 본 논문의 고집적 다운컨버터 MMIC는 싱글 밸런스 믹서, IF증폭기, 액티브형 버룬, 그리고 국부 발진기 주파수(LO) 신호의 누설전력 억제용 필터까지 한 칩에 내장하고 있다. 저잡음특성을 실현하기 위해서, 믹서의 소스부에 소스인덕터가 접속된 소스인덕터 피드백 회로형태의 믹서를 이용하였으며, 그 결과 잡음지수 4.8 dB의 초저잡음 다운컨버터 MMIC가 실현되었다. 이는 종래의 위성방송 수신용 다운컨버터 MMIC의 잡음지수보다 3 dB정도 낮은 수치이다. 그리고, 소비전력을 줄이기 위해 믹서에 대해서 저 LO입력 전력 설계를 수행하였고, 그 결과 믹서의 LO신호 입력부에 위치하는 LO 증폭기가 불필요하게 되었다. 이로인해 본 논문의 다운컨버터 MMIC에 대해서 175 mW(동작전압:5V, 소비전류:35mA)의 저소비전력 특성을 얻을 수 있었으며, 이는 종래의 위성방송 수신용 다운컨버터 MMIC의 소비전력의 70%에 해당한다. 더욱이, IF신호 출력단에서의 LO신호 누설전력을 억제하기 위해서, 스파이럴 인덕터 필터가 본 논문의 MMIC에 내장되었다. 그리고, 다운컨버터 MMIC 칩의 면적을 줄이기 위해, 믹서의 입력부의 X밴드 입력정합회로로서 MMIC 패키지 내부의 본딩 와이어를 이용하였다. 그 결과, $0.84{\times}0.9\textrm{mm}^2$의 초소형 MMIC가 제작되었다. 본 논문의 MMIC 칩 면적은 종래의 위성방송 수신용 MMIC의 50%이하이다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제45회 하계 정기학술대회 초록집
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• pp.99-99
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• 2013

In this talk, I will present two research works in progress, which are: i) mapping of piezoelectric polarization and associated charge density distribution in the heteroepitaxial InGaN/GaN multi-quantum well (MQW) structure of a light emitting diode (LED) by using inline electron holography and ii) in-situ observation of the polarization switching process of an ferroelectric Pb(Zr1-x,Tix)O3 (PZT) thin film capacitor under an applied electric field in transmission electron microscope (TEM). In the first part, I will show that strain as well as total charge density distributions can be mapped quantitatively across all the functional layers constituting a LED, including n-type GaN, InGaN/GaN MQWs, and p-type GaN with sub-nm spatial resolution (~0.8 nm) by using inline electron holography. The experimentally obtained strain maps were verified by comparison with finite element method simulations and confirmed that not only InGaN QWs (2.5 nm in thickness) but also GaN QBs (10 nm in thickness) in the MQW structure are strained complementary to accommodate the lattice misfit strain. Because of this complementary strain of GaN QBs, the strain gradient and also (piezoelectric) polarization gradient across the MQW changes more steeply than expected, resulting in more polarization charge density at the MQW interfaces than the typically expected value from the spontaneous polarization mismatch alone. By quantitative and comparative analysis of the total charge density map with the polarization charge map, we can clarify what extent of the polarization charges are compensated by the electrons supplied from the n-doped GaN QBs. Comparison with the simulated energy band diagrams with various screening parameters show that only 60% of the net polarization charges are compensated by the electrons from the GaN QBs, which results in the internal field of ~2.0 MV cm-1 across each pair of GaN/InGaN of the MQW structure. In the second part of my talk, I will present in-situ observations of the polarization switching process of a planar Ni/PZT/SrRuO3 capacitor using TEM. We observed the preferential, but asymmetric, nucleation and forward growth of switched c-domains at the PZT/electrode interfaces arising from the built-in electric field beneath each interface. The subsequent sideways growth was inhibited by the depolarization field due to the imperfect charge compensation at the counter electrode and preexisting a-domain walls, leading to asymmetric switching. It was found that the preexisting a-domains split into fine a- and c-domains constituting a $90^{\circ}$ stripe domain pattern during the $180^{\circ}$ polarization switching process, revealing that these domains also actively participated in the out-of-plane polarization switching. The real-time observations uncovered the origin of the switching asymmetry and further clarified the importance of charged domain walls and the interfaces with electrodes in the ferroelectric switching processes.

• Molecules and Cells
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• 제37권3호
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• pp.264-269
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• 2014

The molecular interaction between tumor suppressor p53 and the anti-apoptotic Bcl-2 family proteins plays an essential role in the transcription-independent apoptotic pathway of p53. In this study, we investigated the binding of p53 DNA-binding domain (p53DBD) with the anti-apoptotic Bcl-2 family proteins, Bcl-w, Mcl-1, and Bcl-2, using GST pull-down assay and NMR spectroscopy. The GST pull-down assays and NMR experiments demonstrated the direct binding of the p53DBD with Bcl-w, Mcl-1, and Bcl-2. Further, NMR chemical shift perturbation data showed that Bcl-w and Mcl-1 bind to the positively charged DNA-binding surface of p53DBD. Noticeably, the refined structural models of the complexes between p53DBD and Bcl-w, Mcl-1, and Bcl-2 showed that the binding mode of p53DBD is highly conserved among the anti-apoptotic Bcl-2 family proteins. Furthermore, the chemical shift perturbations on Bcl-w, Mcl-1, and Bcl-2 induced by p53DBD binding occurred not only at the p53DBD-binding acidic region but also at the BH3 peptide-binding pocket, which suggests an allosteric conformational change similar to that observed in Bcl-$X_L$. Taken altogether, our results revealed a structural basis for a conserved binding mechanism between p53DBD and the anti-apoptotic Bcl-2 family proteins, which shed light on to the molecular understanding of the transcription-independent apoptosis pathway of p53.

• Restorative Dentistry and Endodontics
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• 제21권2호
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• pp.619-627
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• 1996

There are increasing use of composite resin in the posterior teeth and the new indirect inlay technique was introduced for compensating much troubles faced in direct technique. Many researchers insisted that overall properties of restorative materials were enhanced by an additional curing but this technique still has a problems about using cement material. Resin inlay obtains retention force from friction and another adhesion to tooth structure. A shape of cavity preparation was noted but studies about cement thickness and bond strength with cavity divergency are rare. The purpose of this study is to assess the effect of cavity divergency on cement thickness and bond strength of resin inlay. Cavities, which divergency was $6^{\circ}$, $16^{\circ}$, and $26^{\circ}$ in each group, were prepared and their divergency was verified by Adobe Photoshop program through the image capture with stereo microscope and FlexCam. Inlays were fixed into the cavities with a resin cement, Superbond and were handled under chemical (in 75% ethanol for 24 hrs.) and thermal stress (500 cycles from $5^{\circ}$ to $55^{\circ}C$). MXT 70 (x400) was used for measuring the cement thickness and bond strength was evaluated with a universal testing machine. Following results were obtained : 1. The cement thickness in Mean (S.D.) were; 35.58 (10.31)${\mu}m$ in $6^{\circ}$ group, 35.97 (10.49)${\mu}m$ in $16^{\circ}$ group, and 41.43 (9.33)${\mu}m$ in $26^{\circ}$ group. But there was no significant difference between groups. 2. The bond strength in Mean (S.D.) were ; 33.18 (5.53)kg in $6^{\circ}$ group, 23.47 (13.40)kg in $16^{\circ}$ group, and 19.75 (10.48)kg in $26^{\circ}$ group. $6^{\circ}$ group showed significantly higher value compared to $16^{\circ}$ and $26^{\circ}$ groups (p<0.05). Although the results of this study indicate $6^{\circ}$ divergency will be good for resin inlay, cavity preparation with this type will have lots of difficulties in manufacturing, try-in, and cementation procedures, such as deformation. So it is concluded that $16^{\circ}$ divergent cavity preparation is recommended in resin inlay technique.

• Annals of Laboratory Medicine
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• 제38권6호
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• pp.555-562
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• 2018

Background: The emerging mobile colistin resistance gene, mcr-1, is an ongoing worldwide concern and an evaluation of clinical isolates harboring this gene is required in Korea. We investigated mcr-1-possessing Enterobacteriaceae among Enterobacteriaceae strains isolated in Korea, and compared the genetic details of the plasmids with those in Escherichia coli isolates from livestock. Methods: Among 9,396 Enterobacteriaceae clinical isolates collected between 2010 and 2015, 1,347 (14.3%) strains were resistant to colistin and those were screened for mcr-1 by PCR. Colistin minimum inhibitory concentrations (MICs) were determined by microdilution, and conjugal transfer of the mcr-1-harboring plasmids was assessed by direct mating. Whole genomes of three mcr-1-positive Enterobacteriaceae clinical isolates and 11 livestock-origin mcr-1-positive E. coli isolates were sequenced. Results: Two E. coli and one Enterobacter aerogenes clinical isolates carried carried IncI2 plasmids harboring mcr-1, which conferred colistin resistance (E. coli MIC, 4 mg/L; E. aerogenes MIC, 32 mg/L). The strains possessed the complete conjugal machinery except for E. aerogenes harboring a truncated prepilin peptidase. The E. coli plasmid transferred more efficiently to E. coli than to Klebsiella pneumoniae or Enterobacter cloacae recipients. Among the three bacterial hosts, the colistin MIC was the highest for E. coli owing to the higher mcr-1-plasmid copy number and mcr-1 expression levels. Ten mcr-1-positive chicken-origin E. coli strains also possessed mcr-1-harboring IncI2 plasmids closely related to that in the clinical E. aerogenes isolate, and the remaining one porcine-origin E. coli possessed an mcr-1-harboring IncX4 plasmid. Conclusions: mcr-1-harboring IncI2 plasmids were identified in clinical Enterobacteriaceae isolates. These plasmids were closely associated with those in chicken-origin E. coli strains in Korea, supporting the concept of mcr-1 dissemination between humans and livestock.

• 대한기관식도과학회지
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• 제3권1호
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• pp.94-100
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• 1997

Background and Objectives : In children with tracheal stenosis, operative management remains a challenging problem due to difficulties of operative techniques and postoperative care. The purpose of this study was to determine the effectiveness of tracheal resection with end to end anastomosis as operative management for tracheal stenosis in children. Materials and Methods : 6 children with severe tracheal stenosis underwent tracheal resection with end to end anastomosis. Causes of stenosis were trauma in 1 case and prolonged intubation or tracheotomy in 5 cases. The diagnoses were made by radiologic evaluation (plain X-ray, CT, 3-Dimensional CT) and confirmed by direct laryngoscopy and ventilating bronchoscopy under general anesthesia. Thyroplasty and unilateral arytenoidectomy were performed in 1 case. Suprahyoid release was done in 1 case with severe adhesion. Decanulation was achieved following postoperative endoscopic examination and pulmonary function test. Postoperative physical and radiologic examinations were given at regular intervals. Results : Stenosis were improved from grade III grade I in 4 cases and from grade II to grade I in 2 cases. Decanulation was achieved on average postoperative 6 months in 5 cases, and 10 years in 1 case due to exertional dyspnea. There were 1 each case of immediate postoperative subcutaneous emphysema, pneumothorax and wound infection. Postoperative granulomas at anastomosis site were treated with laser vaporization under suspension laryngoscope and bronchoscope in 3 cases. There was 1 each case of delayed postoperative vocal cord palsy, aspiration pneumonia and loss of cough reflex. Conclusion In tracheal stenosis of children, tracheal resection with end to end anastomosis has good result with preservation of normal airway. Preoperative evaluation of local factors such as swallowing, vocal cord movement and cough reflex and general condition was important for successful treatment. As the cases in adults, authors considered this operation to be a curable operative management for tracheal stenosis.

• 한국광학회지
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• 제32권5호
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• pp.220-229
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• 2021

눈부심 방지를 위한 확산판의 투과율과 연색지수 향상을 위한 양자점 필름의 농도가 고출력 직하형 백색 LED 조명의 광특성에 미치는 영향을 조사했다. 확산판의 투과율이 감소할 경우 조명의 휘도는 줄어들었고 색좌표, 상관색온도는 별다른 변화를 보이지 않았으며 연색지수는 약간 상승했다. 시야각에 따른 광특성의 편차는 거의 없었고 휘도 분포는 람버시안 분포에 가까웠다. 양자점 필름의 농도가 증가할 경우 스펙트럼 상 적색 성분이 늘어나면서 이 성분의 비중을 표현하는 색좌표 x가 증가했고 상관색온도는 약 6000 K에서 4000 K 부근으로 현저히 감소했다. 아울러 조명의 구조를 최적화하면 연색지수가 95까지 증가함을 확인했다. 이런 결과는 적절한 투과율의 확산판과 양자점 필름의 조합을 통해 눈부심이 없고 시야각에 따른 색편차가 거의 없으며 특히 색좌표의 가변이 가능한 고연색성의 조명 구현이 가능함을 보여준다.

• Archives of Hand and Microsurgery
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• 제23권4호
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• pp.254-261
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• 2018

목적: 무지 중수 수지 관절의 척측 측부 인대의 만성 파열에서의 직접 봉합술은 양호한 결과가 보고되고 있으나 요측 측부 인대에서의 결과는 논란이 있다. 본 연구의 목적은 무지 중수 관절의 척측과 요측 측부 인대의 만성 파열에서 인대 재부착술의 결과를 비교하는 것이다. 방법: 무지 중수 수지 관절의 6주 이상된 측부 인대 파열에서 봉합 앵커를 이용해서 재부착술을 시행한 요측 6예 및 척측 8예의 평균 22개월 추적한 방사선적 및 임상 결과를 후향적으로 검토하고, 통계적으로 비교하였다. 결과: 수술 후 평균 척측 변위 각은 요측 측부 인대에서 $13.3^{\circ}$, 척측 측부 인대에서 $2.0^{\circ}$였다(p=0.020). 수술 후 인대 불안정성은 요측 인대 6예 중 4예에서 관찰되었으나, 척측 인대에서는 관찰되지 않았다. 수술 후 경과 관찰에서 관절의 아탈구는 요측 인대 2예에서만 관찰되었다. 결론: 무지 중수 수지 관절의 요측 측부 인대의 지연 봉합은 덜 양호한 결과를 나타내며, 반 이상에서는 수술 후 인대의 불안정성이 관찰된다.

• 한국재료학회지
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• 제28권12호
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• pp.763-768
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• 2018

In this study, glass fibers are fabricated via a continuous spinning process using manganese slag, steel slag, and silica stone. To fabricate the glass fibers, raw materials are put into an alumina crucible, melted at $1550^{\circ}C$ for 2 hrs, and then annealed at $600^{\circ}C$ for 2 hrs. We obtain a black colored glass. We identify the non-crystalline nature of the glass using an XRD(x-ray diffractometer) graph. An adaptable temperature for spinning of the bulk marble glass is characterized using a high temperature viscometer. Spinning is carried out using direct melting spinning equipment as a function of the fiberizing temperature in the range of $1109^{\circ}C$ to $1166^{\circ}C$, while the winder speed is in the range of 100rpm to 250rpm. We investigate the various properties of glass fibers. The average diameters of the glass fibers are measured by optical microscope and FE-SEM. The average diameter of the glass fibers is $73{\mu}m$ at 100rpm, $65{\mu}m$ at 150rpm, $55{\mu}m$ at 200rpm, and $45{\mu}m$ at 250rpm. The mechanical properties of the fibers are confirmed using a UTM(Universal materials testing machine). The average tensile strength of the glass fibers is 21MPa at 100rpm, 31MPa at 150rpm, 34MPa at 200rpm, and 45MPa at 250rpm.

• 지적과 국토정보
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• 제49권1호
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• pp.45-63
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• 2019

본 연구는 최근까지 우리나라는 재산 3분법을 바탕으로 주식, 채권, 실물부동산으로 구성된 전통적인 포트폴리오에 투자하는 것이 대부분이었으나, 포트폴리오 구성시 대표적인 부동산 간접투자상품인 리츠, 부동산펀드 등을 복합적으로 구성한 결과가 투자성과에 미치는 영향을 분석하였다. 이를 위하여 포트폴리오 구성의 가장 적합한 방법인 평균분산모형을 이용한 실증분석을 하였다. 사용변수는 복합자산 포트폴리오를 보유 자산의 구성에 따라 Portfolio A~Portfolio G까지 분류하였으며, 가격지수는 KOSPI, KRX BOND, REITs(TRUS Y7), FUND(HanwhaLasal), OFFICE(Seoul)로 선정하였다. 연구결과는 다음과 같다. 첫 번째의 경우 채권, 주식, 리츠와 부동산펀드가 결합된 Portfolio D와 실물부동산인 오피스가 추가된 Portfolio G의 위험이 가장 낮은 것으로 나타났다. 둘째, 채권, 주식, 리츠로 구성된 Portfolio B와 부동산펀드가 추가된 Portfolio D가 위험이 가장 낮은 것으로 나타났고, 수익률의 경우 채권, 주식, 오피스와 부동산펀드로 구성된 Portfolio F와 리츠까지 편입된 Portfolio G가 가장 높은 것으로 나타났다. 결과적으로 전통적인 재산 3분법으로 구성된 실물부동산 보다 부동산의 비유동성 한계를 제거한 부동산간접투자상품인 리츠와 부동산펀드를 포트폴리오에 구성시 더 효과적인 것으로 분석되었다. 따라서 직접투자의 가장 큰 단점인 비유동성 문제를 해결하여 투자자의 위험을 최소화할 수 있고, 부동산의 소유에 따른 비용을 절감할 수 있으며, 소액으로도 투자가 가능한 부동산 간접투자시장의 활성화가 더욱 필요할 것으로 보인다.