• Title/Summary/Keyword: Direct Coupling

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Direct Palladium-Catalyzed C-4 Arylation of Tri-substituted Furans with Aryl Chlorides: An Efficient Access to Heteroaromatics

  • Yang, Hai;Zheng, Zhishuo;Zeng, Jian;Liu, Huajie;Yi, Bing
    • Bulletin of the Korean Chemical Society
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    • v.33 no.8
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    • pp.2623-2626
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    • 2012
  • A series of functionalized furans were synthesized by way of a palladium-catalyzed coupling reaction of 2,3,5-trisubstituted furans with aryl chlorides through C-H bond cleavages at C-4 position. The feature of the reaction was facilitative preparation of furan derivatives with good functional group tolerance. All reactions gave the desired products in moderate to good yields in the presences of $BuAd_2P$ and t-BuOK in DMF at $120^{\circ}C$ after 15 h.

Study on Steady Flow Effects in Numerical Computation of Added Resistance of Ship in Waves

  • Lee, Jae-Hoon;Kim, Beom-Soo;Kim, Yonghwan
    • Journal of Advanced Research in Ocean Engineering
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    • v.3 no.4
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    • pp.193-203
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    • 2017
  • This study investigated the steady-flow effects present in the numerical computation of the resistance added to a ship in waves. For a ship advancing in the forward direction, a time-domain 3D Rankine panel method is applied to solve the ship motion problem, and the added resistance due to waves is calculated using a near-field method, with the direct integration of the second-order pressure on the hull surface. In the linear potential theory, the steady flow is approximated by the basis potential of a uniform flow or double-body flow in order to linearize the boundary conditions. By applying these two different linearization schemes, the coupling effects between steady and unsteady solutions were examined. Furthermore, in order to analyze the steady-flow effects on the hull geometry, the computation results for two realistic hull forms, a KVLCC2 tanker and DTC containership, were compared. In particular, the mj term, which represents the coupling effects under the body boundary condition, was evaluated considering the geometry of a non-wall-sided ship. Lastly, the characteristics of the linearization schemes were examined in relation to the disturbed waves around a ship and the components of added resistance.

Efficient Analysis of Couplings through Periodically Arranged Slots in a Radial Line Slot Antenna (RLSA 설계를 위한 주기적으로 배열된 슬롯을 통한 결합의 효율적인 해석)

  • 이중원;김용훈;박종국;남상욱
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.12 no.6
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    • pp.931-939
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    • 2001
  • The slot coupling characteristics was analysed in a radial-line slot antenna for its design. The previously proposed waveguide model with a periodic boundary condition on its narrow walls and periodically arranged slots on its wide wall was used. The magnetic field integral equation and two dyadic Green\`s functions for respective regions was derived and the method of moments was used. To maximize the efficiency of numerical analysis and to extract singularities, two different kinds of basis functions, the entire domain basis function and the sub-domain one, are used. In addition, the Ewald sum technique for the rectangular waveguide and the Shanks transform for the half space were used to accelerate the computation of the slowly convergent potential Green\`s functions. Simulation results expressed the effects of the various design parameters on the slot coupling.

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Active Control of Honeycomb Trim Panels for Aircrafts (항공기용 하니콤 트림판넬의 능동제어)

  • Elliott Stephan J.;Jeong, W.B.;Hong, Chin-Suk
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2006.11a
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    • pp.464-473
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    • 2006
  • This paper summarises theoretical and experimental work on the feedback control of sound radiation from honeycomb panels using piezoceramic actuators. It is motivated by the problem of sound transmission in aircraft, specifically the active control of trim panels. Trim panels are generally honeycomb structures designed to meet the design requirement of low weight and high stiffness. They are resiliently-mounted to the fuselage for the passive reduction of noise transmission. Local coupling of the closely-spaced sensor and actuator was observed experimentally and modelled using a single degree of freedom system. The effect of the local coupling was to roll-off the response between the actuator and sensor at high frequencies, so that a feedback control system can have high gain margins. Unfortunately, only relatively poor global performance is then achieved because of localisation of reduction around the actuator. This localisation prompts the investigation of a multichannel active control system. Globalised reduction was predicted using a model of 12 channel direct velocity feedback control. The multichannel system, however, does not appear to yield a significant improvement in the performance because of decreased gain margin.

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Performance Evaluation of Cascade Considering Fluid/Structure Coupling Deformation (유체/구조 연계 변형효과를 고려한 케스케이드의 성능평가)

  • Oh, Se-Won;Kim, Dong-Hyun;Kim, Yu-Sung;Park, Oung
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2007.05a
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    • pp.275-282
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    • 2007
  • In this study, a fluid-structure interaction (FSI) analysis system has been developed in order to evaluate the turbine cascade performance with blade structural deformation effect. Relative movement of the rotor with respect to stator is reflected by modeling independent two computational domains. To consider the deformed position of rotor airfoil, dynamic moving grid method is applied. Reynolds-averaged Navier-Stokes equations with one equation Spalart-Allmaras and two-equation SST $k-{\varepsilon}$ turbulence models are solved to predict unsteady fluid dynamic loads. A fully implicit time marching scheme based on the Newmark direct integration method with high artificial damping is used to compute the fluid-structure interaction problem. Cascade performance evaluations for different elastic axis positions are presented and compared each other. It is importantly shown that the predicted aerodynamic performance considering structural deformation effect of blade can show some deviations compared to the data generally computed from rigid blade configurations and the position of elastic axis also tend to give sensitive effect.

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Delay Measurement and Split-Step Time-Domain Analysis of Ring Resonator All-Pass Filters

  • Kim, Hyosuk;Ko, Yoonyoung;Moon, Hyunseung;Kim, Jaeseong;Chung, Youngchul
    • Journal of the Optical Society of Korea
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    • v.18 no.6
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    • pp.766-771
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    • 2014
  • Single-ring all-pass filters with various coupling ratios are designed, fabricated, and characterized to assess the validity of the split-step time-domain modeling approach, which is considered for direct simulation of time-domain characteristics, such as optical delay, of various ring resonator devices. When the coupling ratio of the single-ring all-pass filter is 0.4 and 0.8, the delay time is measured to be about 145 and 42 ps respectively, which is comparable to the time-domain modeling results of 151 and 47 ps respectively. The measurements for two- and three-ring all-pass filters are also found to agree quite well with the simulation results. With these results it is confirmed that the split-step time-domain model could be efficiently incorporated into an optical-communication simulation module for ring resonator delay components in an all-optical packet switching system.

Safety assessment of caisson transport on a floating dock by frequency- and time-domain calculations

  • Kang, H.Y.;Kim, M.H.
    • Ocean Systems Engineering
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    • v.4 no.2
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    • pp.99-115
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    • 2014
  • When caissons are mounted on a floating transportation barge and towed by a tug boat in waves, motion of the floating dock creates inertia and gravity-induced slip forces on the caisson. If its magnitude exceeds the corresponding friction force between the two surfaces, a slip may occur, which can lead to an unwanted accident. In oblique waves, both pitch and roll motions occur simultaneously and their coupling effects for slip and friction forces become more complicated. With the presence of strong winds, the slip force can appreciably be increased to make the situation worse. In this regard, the safety of the transportation process of a caisson mounted on a floating dock for various wind-wave conditions is investigated. The analysis is done by both frequency-domain approach and time-domain approach, and their differences as well as pros and cons are discussed. It is seen that the time-domain approach is more direct and accurate and can include nonlinear contributions as well as viscous effects, which are typically neglected in the linear frequency-domain approach.

Electrode Characteristics of Non-contact Electrocardiographic Measurement

  • Mathias, Dakurah Naangmenkpeong;Kim, Sung-Il;Park, Jae-Soon;Joung, Yeun-Ho;Choi, Won Seok
    • Transactions on Electrical and Electronic Materials
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    • v.16 no.1
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    • pp.42-45
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    • 2015
  • The ability to take electrocardiographic measurements while performing our daily activities has become the people-choice for modern age vital sign sensing. Currently, wet and dry ECG electrodes are known to pose threats like inflammations, allergic reactions, and metal poisoning due to their direct skin interaction. Therefore, the main goal in this work is to implement a very small ECG sensor system with a capacitive coupling, which is able to detect electrical signals of heart at a distance without the conductive gel. The aim of this paper is to design, implement, and characterize the contactless ECG electrodes. Under a careful consideration of factors that affect a capacitive electrode functional integrity, several different sizes of ECG electrodes were designed and tested with a pilot ECG device. A very small cotton-insulated copper tape electrode ($2.324cm^2$) was finally attained that could detect and measure bioelectric signal at about 500 um of distance from the subject's chest.

Calumenin Interacts with SERCA2 in Rat Cardiac Sarcoplasmic Reticulum

  • Sahoo, Sanjaya Kumar;Kim, Do Han
    • Molecules and Cells
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    • v.26 no.3
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    • pp.265-269
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    • 2008
  • Calumenin, a multiple EF-hand $Ca^{2+}$ binding protein is located in the SR of mammalian heart, but the functional role of the protein in the heart is unknown. In the present study, an adenovirus gene transfer system was employed for neonatal rat heart to examine the effects of calumenin over-expression (Calu-OE) on $Ca^{2+}$ transients. Calu-OE (8 folds) did not alter the expression levels of DHPR, RyR2, NCX, SERCA2, CSQ and PLN. However, Calu-OE affected several parameters of $Ca^{2+}$ transients. Among them, prolongation of time to 50% baseline ($T_{50}$) was the most outstanding change in electrically-evoked $Ca^{2+}$ transients. The higher $T_{50}$ was due to an inhibition of SERCA2-mediated $Ca^{2+}$ uptake into SR, as tested by oxalate-supported $Ca^{2+}$ uptake. Furthermore, co-IP study showed a direct interaction between calumenin and SERCA2. Taken together, calumenin in the cardiac SR may play an important role in the regulation of $Ca^{2+}$ uptake during the EC coupling process.

Identification of binding motifs for skeletal ryanodine receptor and triadin

  • Lee, Jae-Man;Kim, Do-Han
    • Proceedings of the Korean Biophysical Society Conference
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    • 2003.06a
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    • pp.66-66
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    • 2003
  • In skeletal muscle cells, depolarization of the transverse tubules (T-tubules) results in Ca$\^$2+/ release from the sarcoplasmic reticulum (SR), leading to elevated cytoplasmic Ca$\^$2+/ and muscle contraction. This process has been known as excitation-contraction coupling (E-C coupling). Several proteins, such as the ryanodine receptor (RyR), triadin, junctin, and calsequestrin (CSQ), have been identified to be involved in the Ca$\^$2+/ release process. However, the molecular interactions between the SR proteins have not been resolved. In the present study, the mechanisms of interaction between RyRl and triadin have been studied by in vitro protein binding and $\^$45/Ca$\^$2+/ overlay assays. Our data demonstrate that the intraluminal loop II of RyR1 binds to triadin in Ca$\^$2+/-independent manner. Moreover, we could not find any Ca$\^$2+/ binding sites in the loop II region. GST-pull down assay revealed that a KEKE motif of triadin, which was previously identified as a CSQ binding site (Kobayasi et al.,2000 JBC) was also a binding site for RyR1. Our results suggest that the intraluminal loop II of RyR could participate in the RyR-mediated Ca$\^$2+/ release process by offering a direct binding site to luminal triadin.

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